• Biomolecules & Therapeutics
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• v.26 no.4
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• pp.368-373
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• 2018

Rapid eye movement (REM) sleep has an essential role in the process of learning and memory in the hippocampus. It has been reported that linalool, a major component of Lavandula angustifolia, has antioxidant, anti-inflammatory, and neuroprotective effects, along with other effects. However, the effect of linalool on the cognitive impairment and behavioral alterations that are induced by REM-sleep deprivation has not yet been elucidated. Several studies have reported that REM-sleep deprivation-induced memory deficits provide a well-known model of behavioral alterations. In the present study, we examined whether linalool elicited an anti-stress effect, reversing the behavioral alterations observed following REM-sleep deprivation in mice. Furthermore, we investigated the underlying mechanism of the effect of linalool. Spatial memory and learning memory were assessed through Y maze and passive avoidance tests, respectively, and the forced swimming test was used to evaluate anti-stress activity. The mechanisms through which linalool improves memory loss and behavioral alterations in sleep-deprived mice appeared to be through an increase in the serotonin levels. Linalool significantly ameliorated the spatial and learning memory deficits, and stress activity observed in sleep-deprived animals. Moreover, linalool led to serotonin release, and cortisol level reduction. Our findings suggest that linalool has beneficial effects on the memory loss and behavioral alterations induced by REM-sleep deprivation through the regulation of serotonin levels.

• Journal of the Korean Society for Precision Engineering
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• v.16 no.2 s.95
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• pp.218-224
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• 1999

In the feed drive systems of machine tools that consist of many mechanical components such as motor, coupling, ballscrew, nut or table, a torsional vibration is often generated because of its elastic elements in torque transmission. Generally, the accuracy of motion control system is strongly influenced by the dynamic behavior of coupled transmission components. Especially, a torsional vibration caused by the elasticity of mechanical elements might deteriorate the quick movement of system and lead to shorten the life time of the mechanical transmission elements. So, it is necessary to analyze the electromechanical system mathematically to optimize the dynamic characteristics of the feed system. In this paper, the mathematical model of a feed drive system was developed and its mechanical characteristics were analyzed on the basis of the proposed model. The design concepts of speed control loop to stabilize a feed drive system were also proposed.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.27 no.1
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• pp.109-118
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• 2003

The recent trend towards miniaturization causes an increased demand for parts with very small dimensions. Milli-structure components are classified as a component group whose size is between macro- and micro-scale. The manufacturing process of these components of thin sheet metal forming has a microscopic properties in addition to a typical phenomenon of bulk deformation because of the forming size. Also, the material properties and the deformation behavior change with miniaturization, which means that, a coarse grained materials show a higher resistance against deformation, when the grain size is in the range of the sheet thickness. In this study, a new numerical approach is proposed to simulate intergranular milli-structure in forming by the finite element method. The grain element and grain boundary element are introduced to simulate the milli-structure in the bending. The grain element is used to analyze the deformation of individual grain while the grain boundary element is for the investigation on the movement of the grain boundary. Also, the result of the finite element analysis is confirmed by a series of milli-sized forming experiments.

• Journal of Internet Computing and Services
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• v.5 no.5
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• pp.49-60
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• 2004

Information Warfare(IW), a new aspect of war, is the field centralized the concern and research in the information security and national security, Both the defense and the offensive are important in the next generation IW, and so we need to do the various research to secure the network and system for gaining the superiority of IW. This paper proposes a model for IW based on software cruise to prepare the IW that is changing the offensive aspect. Software cruise is defined as a behavior of computer programs that travel toward specific destination from a source through the network. The proposed model have the cruise property and uses the cybermap to cruise toward the destination chosen in advance. Also, while self-movement, the model can function the predefined task.

• Advances in materials Research
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• v.4 no.3
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• pp.165-178
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• 2015

Friction coefficient of epoxy metal matrix composites were investigated. The main objective was to increase the friction coefficient through rubber sole sliding against the epoxy floor coating providing appropriate level of resistance. This was to avoid the excessive movement and slip accidents. Epoxy metal matrix composites were reinforced by different copper wire diameters. The epoxy metal matrix composites were experimentally conducted at different conditions namely dry, water and detergent wetted sliding, were the friction coefficient increased as the number of wires increased. When the wires were closer to the sliding surface, the friction coefficient was found to increase. The friction coefficient was found to increase with the increase of the copper wire diameter in epoxy metal matrix composites. This behavior was attributed to the fact that as the diameter and the number of wires increased, the intensity of the electric field, generated from electric static charge increased causing an adhesion increase between the two sliding surfaces. At water wetted sliding conditions, the effect of changing number of wires on friction coefficient was less than the effect of wire diameter. The presence of water and detergent on the sliding surfaces decreased friction coefficient compared to the dry sliding. When the surfaces were detergent wetted, the friction coefficient values were found to be lower than that observed when sliding in water or dry condition.

• International Journal of Automotive Technology
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• v.7 no.5
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• pp.555-564
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• 2006

The aim of this paper is to contribute to the efficient design of traffic light poles involved in vehicle frontal collisions by developing a computer-based, finite-element model capable of capturing the impact characteristics. This is achieved by using the available non-linear dynamic analysis software "LS-DYNA3D", which can accurately predict the dynamic response of both the vehicle and the traffic light pole. The fiber reinforced polymer(FRP) as a new pole's material is proposed in this paper to increase energy absorption capabilities in the case of a traffic pole involved in a vehicle head-on collision. Numerical analyses are conducted to evaluate the effects of key parameters on the response of the pole embedded in soil when impacted by vehicles, including: soil type(clay and sand) and pole material type(FRP and steel). It is demonstrated from the numerical analysis that the FRP pole-soil system has favorable advantages over steel poles, where the FRP pole absorbed vehicle impact energy in a smoother behavior, which leads to smoother acceleration pulse and less deformation of the vehicle than those encountered with steel poles. Also, it was observed that clayey soil brings a slightly more resistance than sandy soil which helps reducing pole movement at ground level. Finally, FRP pole system provides more energy absorbing leading to protection during minor impacts and under service loading, and remain flexible enough to avoid influencing vehicle occupants, thus reducing fatalities and injuries resulting from the crash.

• Korean Journal of Psychosomatic Medicine
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• v.4 no.1
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• pp.44-53
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• 1996

The present experiment was designed to investigate the effects of behavioral, response to immune function in response to electric footshock in mice. Mice were subjected to electric footshock for 3 days(two sessions a day, 11 times of shock for about 31 minutes a session). The humoral immune response was measured using mice immunized with rat RBC. The cell-mediated immune responses were evaluated by contact hypersensitivity to 2, 4-dinitrofluorobenzene(DNFB) and by phytohemagglutin(PHA)-stimulated splenocytes proliferation assay. In stressed group, electric footshock suppressed significantly anti-rat RBC antibody production(p<0.05), but enhanced significantly $T_{48}$ relative to $T_{24}$ in contact hypersenstivry (P<.01) and T-cell proliferation response(P<.05) by PHA stimulation elative to control group. T-cell proliferation response by PHA stimulation was significantly correlated to the movement than the sensitivity and coping behavior in the mouse, in response to the electric footshock. These data supper the importance of behavioral response in stress-induced changes of immune functions.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.7 no.4
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• pp.697-703
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• 2006

In this research, model tests for in-situ Top-Base Foundation are carried out in other to investigate the load delivering mechanism and the incremental effect of bearing capacity. According to the result of model tests, the load-settlement curves of both in-situ Top-Base(In-situ TBF) and Precast Top-Base Foundation(PC-TBF) showed similar results in term of the ground movement and effect of bearing capacity. Also, the range of vertical stresses delivered into ground was decreased with Top-Base method regarding other types foundations.

• The Korean Journal of Physiology and Pharmacology
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• v.13 no.6
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• pp.469-473
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• 2009

Induced activation of the gamma-aminobutyric $acid_A$ ($GABA_A$) receptor in the retina of goldfish caused the fish to rotate in the opposite direction to that of the spinning pattern during an optomotor response (OMR) measurement. Muscimol, a $GABA_A$ receptor agonist, modified OMR in a concentration-dependent manner. The $GABA_B$ receptor agonist baclofen and $GABA_C$ receptor agonist CACA did not affect OMR. The observed modifications in OMR included decreased anterograde rotation $(0.01\sim0.03\;{\mu}M)$, coexistence of retrograde rotation and decreased anterograde rotation $(0.1\sim30\;{\mu}M)$ and only retrograde rotation $(100\;{\mu}M\sim1\;mM)$. In contrast, the $GABA_A$ receptor antagonist bicuculline blocked muscimol-induced retrograde rotation. Based on these results, we inferred that the coding inducing retrograde movement of the goldfish retina is essentially associated with the GABAA receptor-related visual pathway. Furthermore, from our novel approach using observations of goldfish behavior the induced discrete snapshot duration was approximately 573 ms when the fish were under the influence of muscimol.

• The KIPS Transactions:PartB
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• v.9B no.1
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• pp.35-46
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• 2002

The EEG is a time series of electrical potentials representing the sum of a very large number of neuronal dendrite potentials in the brain. The collective dynamic behavior of neural mass of different brain structures can be assessed from EEG with depth electrodes measurements at regular time intervals. In recent years, the theory of nonlinear dynamics has developed methods for quantitative analysis of brain function. In this paper, we considered it is reasonable or not for ICA apply to EEG analysis. Then we applied ICA to EEG for big toe movement and separated the independent components for 15 samples. The strength of each independent component can be represented on the topological map. We represented ICA can be applied for time and spatial analysis of EEG.