• Asian Pacific Journal of Cancer Prevention
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• v.17 no.7
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• pp.3611-3614
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• 2016

Background: Propolis based preparations have a wide range of applications in various specialties of dentistry. The aim of this clinical trial was to test the efficacy of propolis as a mouthwash in the reduction of chemotherapy induced oral mucositis (OM) in a single center. Materials and Methods: In this randomised, controlled study patients undergoing chemotherapy were included consecutively and randomised to an experimental group receiving propolis mouthwash (n = 20) and a control group receiving diluted water (n=20). Oral mucositis, erythema and eating and drink ability were assessed at baseline and after 3 and 7 days using the World Health Organization (WHO) scale and the oral mucositis assessment scale (OMAS). Results: There were significant differences in OM, wound and erythema in propolis group compared to placebo, but no significant difference in eating and drink ability. However, it was interesting that 65% of the patients in the propolis group were completely healed at day 7 of the trial. No significant adverse events were reported by the patients. Conclusions: This study found that oral care with propolis as mouthwash for patients undergoing chemotherapy is an effective intervention to improve oral health. Our findings shouldlencourage health practitioners to apply propolis mouth rinse for the oral care of patients under chemotherapy.

• The Journal of the Korean dental association
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• v.48 no.5
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• pp.371-378
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• 2010

The objective of this study was to compare the effectiveness of essential oil mouthrinse and interdental brush for oral hygiene in orthodontic patient. 90 patients, with fixed orthodontic appliances, were divided into 3 groups(Group 1: patients who had only used toothbrush, group 2: toothbrush + essential oil mouthrinse, group 3: toothbrush + interdental brush). Then, plaque index(PI) and gingival index(GI) were evaluated at before(T0), 3 weeks after(Tl) and 6 weeks after(T2) the experiment. The present study revealed the following conclusions: (1) There was statistically significant decrease in PI and GI of groups 2 and 3 comparing to those of group 1 during 6 weeks.(p<0.05) (2) There was no significant difference in the level of decrease in PI and GI between group 2 and group 3.(p<0.05) The present study thus implied that use of mechanical or chemical aid such as interdental brush and mouth rinse in addition to toothbrushing may help maintaining oral hygiene in patients undergoing fixed orthodontic treatment for prolonged duration.

• The Journal of the Korean dental association
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• v.55 no.2
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• pp.180-188
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• 2017

Introduction : Inadequate oral health control is a major risk of oral diseases. Regular home-based care is essential to maintain good oral hygiene. In particular, mouthrinses can support conventional tooth brushing in reducing accumulation of oral plaque. Effect : Antimicrobial mouthrinses are used as part of daily oral care to reduce plaque and gingivitis. Mouthrinses contains fluoride could help remineralization of enamel and dentin. The most common molecules contained in mouthrinses are chlorhexidine, essential oils, cetyl pyridinium chloride, triclosan, hyaluronic acid. Currently, chlorhexidine is the most efficacious compound, with both antiplaque and antibacterial activities. Similar results are reported for essential oils and cetyl pyridinium chloride, although with a somewhat reduced efficacy. Considering the adverse effects of chlorhexidine and its time-related characteristics, this molecule may best be indicated for acute/short term use, while essential oils and cetyl pyridinium chloride may be appropriate for long-term, maintenance treatment. Conclusion and suggestion : Antimicrobial mouthrinses are safe and effective, and when used in conjunction with brushing and flossing, they are an important method of reducing plaque and gingivitis. To improve compliance, dental health care professionals should adapt oral health care recommendations to fit patients' specific needs.

• International Journal of Oral Biology
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• v.39 no.1
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• pp.35-40
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• 2014

Halitosis is caused by consumption of certain foods or drinks and production of volatile sulfur compounds (VSCs) by periodontopathogens. VSCs-related halitosis is not easily removed using mechanical or chemical therapies such as dental floss, plaque control and mouth rinse. Lactobacillus are known to be probiotics and stimulate immune systems of human. Furthermore, L. casei ATCC 334 and L. rhamnosus GG have an effect on protection of dental caries in vitro studies. The aim of this study was to investigate effect of Lactobacillus on halitosis by Fusobacterium nucleatum- and Porphyromonas gingivalis-producing VSCs and to analyze inhibitory mechanism. The periodontopathogens were cultivated in the presence or the absence Lactobacillus, and the level of VSCs was measured by gas chromatograph. For analysis of inhibitory mechanisms, the susceptibility assay of the spent culture medium of Lactobacillus against F. nucleatum and P. gingivalis was investigated. Also, the spent culture medium of Lactobacillus and periodontopathogens were mixed, and the emission of VSCs from the spent culture medium was measured by gas chromatograph. L. casei and L. rhamnosus significantly reduced production of VSCs. L. casei and L. rhamnosus exhibited strong antibacterial activity against F. nucleatum and P. gingivalis. The spent culture medium of L. casei inhibited to emit gaseous hydrogen sulfide, methyl mercaptan and dimethyl sulfide from the spent culture medium of periodontopathogens. However, the spent medium of L. rhamnosus repressed only dimethyl sulfide. L. casei ATCC 334 may improve halitosis by growth inhibition of periodontopathogens and reduction of VSCs emission.

• Journal of Korean society of Dental Hygiene
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• v.19 no.1
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• pp.151-159
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• 2019

Objective: This study aimed to investigate the relation between rinsing time and the change in enamel surface after fluoride application on the enamel surface. Methods: We recruited two sample groups with different mouth rinsing times. While one group rinsed the teeth immediately after applying acidulated phosphate fluoride (APF) gel, the other group rinsed the teeth 30 minutes after APF gel application. In each group, we performed the following four-step experiment: (i) apply APF gel on the teeth, (ii) rinse the teeth, (iii) immerse the teeth in orange juice, and (iv) measure enamel surface microhardness and scan enamel surfaces. Results: The group that rinsed 30 minutes after treatment exhibited greater microhardness than the group that rinsed immediately after fluoride treatment. The former also showed smooth and regular crystallization, whereas the latter showed rough and damaged crystallization and irregular surfaces. Conclusions: Based on these observations, we conclude that delaying the rinsing time improves the dental caries preventive effect of fluoride.

• Journal of the korean academy of Pediatric Dentistry
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• v.26 no.2
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• pp.262-274
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• 1999

Several alternatives for increasing the fluoride concentration in the mouth, such as water fluoridation, ingestion of fluoride supplements, fluoride paste, fluoride mouthrinse, application of fluoride gel are available. There is an impressive body of evidence that the topically deliverd fluorides are clinically effective in inhibiting the progression of dental caries. Recent studies on the cariostatic action of fluoride have indicated the importance of fluoride in the fluid environment of the teeth. The fluoride levels in unstimulated whole saliva can be considered indicative of F in the aqueous phase available for interaction with the tooth surface at a given time. The retention of F in the mouth after topical fluoride treatment is considered to be an important factor in the clinical efficacy of F. The aim of this study was to determine the elevation and clearance of fluoride in whole saliv after the following topical flouride treatments using HMDS-diffusion technique and fluoride ion electrode. The obtained results were as follow: 1. Average salivary fluoride concentration in the unstimulated whole saliva was $0.0152ppm{\pm}0.0091ppm$. Unstimulated salivary flow rate was between 0.34-0.36ml/min and there was no statistically significant difference among the groups(p>0.05). 2. Except for the immediate time after treatment, fluoride levels followed as APF gel>neutral gel>F-rinse>F-paste. There was no statistical difference between the salivary F concentration of F-paste group and that of control group after 2 hours. In case of F-rinse group, after 3 hours the concentration had dropped to baseline value. But there was statistically significant difference among the F concentraion of F gel groups and that of control group(p<0.05). 3. The mean $AUC_{0-120min}$ values were followed as neutral gel>APF gel>F-rinse>F-paste, and the values of the two former groups were significantly higher than those of the two latter groups(p<0.05).

• Journal of Oral Medicine and Pain
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• v.32 no.2
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• pp.151-156
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• 2007

Antimicrobial action of phytoncide in the mouth decrease odor-producing microorganisms. Also phytoncide has malodor effect by reaction with volatile sulfur compounds. Phytoncide has excellent malodor effect in microbiologically and chemically. This study prove the malodor effect of phytoncide by use ferrous sulfate. So I try to make new treatment method for halitosis. I get the results as follows. 1. The difference of mean value of absorbancy was 0.849 between the mean absorbancy of deposition by add phytoncide to saliva and the saliva only. 2. The difference of mean value of absorbancy was 0.701 between the mean absorbancy of deposition by add phytoncide to distilled water and the distilled water only. 3. The difference of mean value(0.849) in saliva by existence of phytoncide was larger than in double distilled water(0.701) by existence of phytoncide. Therefore, phytoncide make more deposition in saliva than double distilled water by reaction with sulfur compounds. As the results, phytoncide reaction with sulfur compounds in saliva. It take malodor action in liquid state effectively. It is thought, only the toothpaste it knows from in the limit which does not have a side effect by the human body it adds in the oral cavity of the mouth rinse and with the fact that it will be able to use positively in clinic.

• Journal of dental hygiene science
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• v.11 no.5
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• pp.397-404
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• 2011

The aims of this study were to evaluate the effect of native acidity upon dental hard tissues by measuring pH in mouth-rinse, which is on the market, and to evaluate even influence of dental stain caused by mouse-rinse given using for a long time. The experimental group was used Garglin, Nextcare, Listerine, and Hexamedin. The control group was used sterile distilled water. As a result, pH was indicated to be low in Nextcare(4.70) and Listerine(4.16). In a change of color tone, $b^*$ value of indicating Yellow-blue showed the lower value than the early color tone in all groups. There was statistical significance in Nextcare and Listerine. ${\Delta}L^*$ value of indicating light -dark gets darker after using Nextcare, Listerine and Hexamedine. A change(VHN) in surface hardness of enamel showed reduction in surface hardness after 14 days in Nexcare and Listerine. As a result of confirming a change in enamel surface by using Scanning Electron Microscopy, the erosion aspect on the enamel surface could be confirmed in groups of Nexcare and Listerine. Ra value in surface roughness of enamel could be observed the enamel surface, which got rougher compared to other experimental groups.

• Journal of dental hygiene science
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• v.19 no.4
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• pp.288-293
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• 2019

Background: Dental caries is one of several prevalent oral diseases caused by dental plaque biofilms. This study evaluated the anti-cariogenic effects of a bamboo salt (BS) and sodium fluoride (NaF) mixture on oral bacteria. Methods: The effects of several mixtures of NaF and BS on acid production, growth, and adhesion to glass beads of Streptococcus mutans, and their anti-cariogenic properties were investigated. The growth of S. mutans was measured according to optical density at 3, 6, 9, 12, 15, 18, and 24 hours after treatment using spectrophotometry at a wavelength of 600 nm, while pH was measured using a pH meter. Adhesion of S. mutans was measured according to the weight of glass beads from each group before and after incubation. Gene expression was measured using real-time polymerase chain reaction. Acid production and growth patterns of S. mutans were compared using repeated measures analysis of variance, followed by Scheffe's post-hoc test. The Kruskal-Wallis test was used to compare adhesion, followed by the Mann-Whitney test. Gene expression in the experimental and control samples was compared using the Student's t-test. Results: Growth, acid production, and adhesion of S. mutans were inhibited in all experimental groups. Expression of gft and fructosyltransferase in S. mutans was inhibited in all groups. A mixture of NaF and BS significantly reduced growth, acid production, adhesion, and gene expression of S. mutans compared with the other groups. Conclusion: Results of the present study demonstrated that a mixture of NaF and BS was useful as a mouth rinse in preventing dental caries.

• Journal of the Korean Society of School Health
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• v.14 no.1
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• pp.107-114
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• 2001

The purpose of this study was to collect basic data for the development of oral health education program of parents and to encourage their actual interest and participation in school oral health program. The authors surveyed parents' awareness and behaviors about the oral health of their children. The subjects in this study were 193 parents of elementary school children in Seoul. The collected data were analyzed, the obtained results were as follows: 1. Thirty-five percent of the parents investigated paid a regular visit to a dental clinic. The most common tooth brushing time among them was after dinner, the second was after breakfast, and this was followed by before bedtime and before breakfast 2. Ninety-four percent of the parents responded that prevention is necessary, 92.2% had a plan to visit a dental clinic to prevent dental caries, and 60.1% experienced receiving pit and fissure sealants. Ninety-seven percent responded that they did check their children's dental caries. 54.9% checked their children's oral status after tooth brushing. The parents who visit a dental clinic on a regular basis were more likely to check their children's teeth after tooth brushing than those who don't(P<0.05). 3. Eighty eight percent of respondents wanted to keep the fluoride mouth rinse program. 4. It is recommended that an oral health education program be developed for parents to visit dental clinics on a regular basis, to educate as to the right tooth brushing time, and to check out their children's oral status after tooth brushing.