• Title/Summary/Keyword: Motor unit number estimation

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Reproducibility of Statistical Motor Unit Number Estimate in Amyotrophic Lateral Sclerosis: Comparisons between Size-and Number-Weighted Modifications (근위축성 측삭 경화증에서의 Statistical Motor Unit Number Estimate 재연성: Size-and Number-Weighted Modifications간의 비교)

  • Kwon, Oh Yun;Lee, Kwang-Woo
    • Annals of Clinical Neurophysiology
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    • v.5 no.1
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    • pp.27-33
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    • 2003
  • Background: Motor unit number estimation (MUNE) can directly assess motor neuron populations in muscle and quantify the degree of physiologic and/or pathologic motor neuron degeneration. A high degree of reproducibility and reliability is required from a good quantitative tool. MUNE, in various ways, is being increasingly applied clinically and statistical MUNE has several advantages over alternative techniques. Nevertheless, the optimal method of applying statistical MUNE to improve reproducibility has not been established. Methods: We performed statistical MUNE by selecting the most compensated compound muscle action potential (CMAP) area as a test area and modified the results obtained by weighted mean surface-recorded motor unit potential (SMUP). Results: MUNE measures in amyotrophic lateral sclerosis (ALS) patients showed better reproducibility with sizeweighted modification. Conclusions: We suggest size-weighted MUNE testing of "neurogenically compensated"CMAP areas present an optimal method for statistical MUNE in ALS patients.

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Categorization of Motor Operated Valve Safety Significance for Its Periodic Safety Verification (모터구동 밸브 주기적 안전성 확인을 위한 중요도 분류)

  • Sung, Tae-Young;Kim, Kil-Yoo;Kang, Dae-Il
    • Journal of the Korean Society of Safety
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    • v.17 no.2
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    • pp.92-99
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    • 2002
  • Safety-related motor operated valve(MOV) safety significance for Ulchin Unit 3 was categorized. The safety evaluation of MOV of domestic nuclear power plants affects the generic data used for the quantification of MOV common cause failure(CCF) events in Ulchin Units 3&4 PSA. Therefore, in this paper, MGL(multiple greek letter)parameter ${\beta}$, used for the evaluation of MOV CCF probabilities in Ulchin Units 3&4 probabilistic safety assessment(PSA), was re-estimated and the MOV safety significance was categorized. The re-estimation results of MGL parameter show that the value of(is decreased by 30% compared with the current value used in Ulchin Unit 3&4 PSA. The categorization results of MOV safety significance using the changed value of MGL parameter(show that the number of HSSCs(high safety significant components) is decreased by 54.5% compared with those using the current value of it used in Ulchin Units 3&4 PSA.

A Study on Estimation of Numbers of Motor Unit related to the Widths and Distribution of Endplate in Neuromuscular Junction (신경근육 접합부의 종판 폭과 분포에 따른 운동단위 수의 추정에 관한 연구)

  • Lee, Ho-Yong;Kim, Duck-Young;Park, Jung-Ho;Jung, Chul-Ki;Kim, Sung-Hwan
    • Journal of the Institute of Electronics Engineers of Korea SC
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    • v.48 no.5
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    • pp.81-92
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    • 2011
  • In this paper, a new method to estimate the number of MU (motor unit) related to the widths and distribution of end plate in NMJ (neuromuscular junction) of biceps brachii is proposed by varying muscle parameter statistically in EMG model. This work is done by designing MU-simulator and EPZ-simulator. The proposed method was compared with the results of previous researchers. The proposed MU-simulator generates SMUAP (single motor unit action potential) and CMAP (compound muscle action potential) signal similar to detected SMUAP and CMAP signal obtained from muscle. The EPZ-simulator estimate the numbers of MU by varying the widths and distribution of end plate in neuromuscular junction of muscle. The results shows that the numbers of MU was estimated about 450 ea. and muscle fibers was about 340 ea., end plate widths was about 6 mm, and end plate was randomly distributed. The proposed method may be comparable with the method of anatomical studies.

A Study on the Low Force Estimation of Skeletal Muscle by using ICA and Neuro-transmission Model (독립성분 분석과 신전달 모델을 이용한 근육의 미세한 힘의 추정에 관한 연구)

  • Yoo, Sae-Keun;Youm, Doo-Ho;Lee, Ho-Yong;Kim, Sung-Hwan
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.56 no.3
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    • pp.632-640
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    • 2007
  • The low force estimation method of skeletal muscle was proposed by using ICA(independent component analysis) and neuro-transmission model. An EMG decomposition is the procedure by which the signal is classified into its constituent MUAP(motor unit action potential). The force index of electromyography was due to the generation of MUAP. To estimate low force, current analysis technique, such as RMS(root mean square) and MAV(mean absolute value), have not been shown to provide direct measures of the number and timing of motoneurons firing or their firing frequencies, but are used due to lack of other options. In this paper, the method based on ICA and chemical signal transmission mechanism from neuron to muscle was proposed. The force generation model consists of two linear, first-order low pass filters separated by a static non-linearity. The model takes a modulated IPI(inter pulse interval) as input and produces isometric force as output. Both the step and random train were applied to the neuro-transmission model. As a results, the ICA has shown remarkable enhancement by finding a hidden MAUP from the original superimposed EMG signal and estimating accurate IPI. And the proposed estimation technique shows good agreements with the low force measured comparing with RMS and MAV method to the input patterns.

A Study on Greenhouse Gas Emissions Estimation based on Mileage Through Accumulation of Activity Databases (활동자료 구축을 통한 주행거리 기반의 온실가스 배출량산정방법에 관한 연구)

  • Bae, Bo Ram;Kim, Gyeong Seok
    • Journal of Korean Society of Transportation
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    • v.32 no.1
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    • pp.1-12
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    • 2014
  • The tier 3 methodology used in estimation of greenhouse gas emissions from road sectors is based on mileage data. However, such data can neither accurately represent the mileage of regional unit nor have sufficient integrated data reflecting the characteristics by region, vehicle type, fuel type and road type. Such estimation of greenhouse gas emissions is not reliable. Accordingly, the purpose of this study is, firstly to accumulate activity data based on distance traveled which enables us to accurately estimate the amount of green gas emitted by regional unit(emission point), and secondly, to develop a methodology for estimation of greenhouse gas emissions using these data. To do this, the study utilizes the mileage data of Korea Transportation Safety Authority(TS), statistics of registered motor vehicles, statistical yearbook of traffic volume from the Ministry of Land, Infrastructure and Transport(MLIT), the Korea Transport Database of the Korea Transport Institute(KOTI), and average road speed by local government. Methodology for estimation by local government level(emission point) is meaningful, because it reflects traffic pattern data including flow in and out and internal traffics. Finally, to verify the methodology presented in this study, it is applied to Seoul. Both greenhouse gas estimates, one by multiplying the average mileage and the number of registered vehicles and the other by multiplying traffic volume and road extension, are less than the amount estimated by the methodology presented in this study.