• 한국식품저장유통학회지
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• 제9권2호
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• pp.228-233
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• 2002

뽕나무 어린줄기를 이용하여 새로운 기능성 추출 음료개발을 위한 목적으로 뽕나무 줄기의 화학성분, 항산화 및 항균활성을 조사하였다. 일반성분은 조섬유 51.12%, 회분 13.46%, 총당 10.38%, 조지방 9.10% 및 조단백 5.01% 순으로 나타났다 뽕나무 어린줄기에 가장 많은 무기성분으로는 P(295.9 mg%)으로 나타났으며, 그 외 Ca 289.6 mg%, K 209.6 mg%, Na 58.3 mg%, Mg 45.0 mg% and Fe 4.6 mg% 순으로 나타났다. 유리당은 총 4종이 분리, 동정되었으며, 그 중 glucose가 1.08%로 높게 나타났고, galactose 0.22%, sucrose 0.20% 및 fructose 0.16%로 함유되어 있었다. 지방산은 8종이 분리되었으며, 주된 지방산으로는 linoleic acid, palmitic acid 및 linolenic acid로 나타났다. 분리된 18종의 총 아미노산 중 proline이 313.7mg%로 가장 높은 함량을 차지하였으며, 총 아미노산함량은2,450.5 mg%로 나타났다. 항산화 효과는 용매별 추출물에서는 methanol 추출물이 77.24%, 용매분획별 추출물에서는 ethyl acetate 분획층에서 80.08%로 각각 높게 나타났다. 뽕나무 어린 줄기의 메탄올 추출물은 Bacillus subtilis와 Bacillu scereus에 대하여 강한 항균활성을 나타내었다. 메탄을 추출물의 chloroform 분획층과 ethyl acetate분획층에서 병원성 미생물에 대하여 9.0~l9.0 mm의 저해활성을 나타내었다.

• Nutrition Research and Practice
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• 제16권6호
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• pp.716-728
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• 2022

BACKGROUND/OBJECTIVES: An imbalanced adipokine profile in obesity increases the susceptibility to obesity-related cardiometabolic alterations, including type 2 diabetes, hypertension, dyslipidemia, and non-alcoholic fatty liver disease. The mulberry plant has been reported to have health benefits, such as hypolipidemic and hepatoprotective effects. This study examined the effects of a mulberry (Morus alba L.) fruit ethanol extract (MBEE) on dyslipidemia, liver steatosis, and adipokine imbalance in response to a high-fat diet. MATERIALS/METHODS: Male Sprague-Dawley rats were assigned to one of 4 groups containing 6 rats each and fed either a control diet (CON), a high-fat diet (HFD), or a high-fat diet with MBEE of 150 mg/kg/day (LMB) or 300 mg/kg/day (HMB). The triglyceride (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), alanine aminotransferase (ALT), and aspartate aminotransferase (AST) activities were measured spectrophotometrically. The leptin, adiponectin, and plasminogen activator inhibitor-1 (PAI-1) levels were determined by an enzyme-linked immunosorbent assay. RESULTS: The plasma TG levels were similar in the 4 groups. Plasma cholesterol and low-density lipoprotein cholesterol (LDL-C) levels and TC/HDL-C ratio increased in the HFD group compared with the CON group, whereas those values decreased in the LMB group (P < 0.05), indicating that MBEE had a plasma lipid-lowering effect. HDL-C decreased in the HFD group, but MBEE did not affect the HDL-C level. The HFD rats significantly increased hepatic TG and cholesterol levels and plasma ALT and AST activities compared to the CON group. The hepatic TG level and ALT and AST activities were reduced markedly by the MBEE treatment. The HFD group showed a higher PAI-1 level, whereas MBEE treatment, especially in the HMB group, significantly reduced leptin level, and leptin/adiponectin and PAI-1/ adiponectin ratios. These findings suggest that MBEE altered the imbalance between the pro-and anti-inflammatory adipokines to a more anti-inflammatory state. CONCLUSIONS: MBEE could protect against abnormal lipid metabolism and hepatic steatosis induced by a high-fat diet, lowering plasma cholesterol, LDL-C and TC/HDL-C, and hepatic TG. These findings are associated with the regulating effect of MBEE on the leptin/adiponectin and PAI-1/adiponectin ratios.

• International Journal of Industrial Entomology and Biomaterials
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• 제42권2호
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• pp.25-32
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• 2021

Mulberry fruit (Morus alba L.) contains phytochemicals, including 1-deoxynojirimycin, quercetin-glucoside, kaempferol-glucoside, and anthocyanins, which have antioxidant effects. In this study, mulberry fruit extract was prepared at various temperatures (25-100℃) and water/ethanol solvent concentrations (0%-100% ethanol). Fourier-transform infrared spectroscopy (FT-IR) and circular dichroism (CD) data indicated that the content of bioactive compounds such as polyphenols and flavonoids was lower in 100% ethanolic extracts than in 30%-50% ethanolic extracts. Radical scavenging activity determined using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-di-3-ethylbenzthiazoline sulfonic acid (ABTS) assays was highly correlated with polyphenol and flavonoid content. In conclusion, 30%-50% ethanolic extracts contained the highest contents of bioactive compounds and exhibited high levels of radical scavenging activity. These findings may inform the use of mulberry fruit extract as a functional food.

• 한국식생활문화학회지
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• 제12권5호
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• pp.567-572
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• 1997

This reserch was carried out to investigate the nitrite scavenging abilities (NSA) of 7 kinds of tea extracts. Nitrites are used as additives of cured meat preperation and exist in plants, foods, and medicines, so we intake it very often easily. Nitrites can act with amines to produce nitrosamine which is known to be a carcinogen. It is known that the pH, concentration of amines, and amounts of nitrite are three important conditions of nitrosamine occurence. 7 kinds of tea used in this experiment were Persimmon tree (Diospyroo kaki Thiunb, Per.), Mulberry tree (Morus alba Linne, Mul.), Rubber tree (eucommia ulmoi-des Oliver, Rub.), Solomon's-seal (Bolygonatu Morr, Som.), Chicory (Cichorrium intybus L, Chi.), Sumach (Rhus javanica L., Sum.), Docwood (Cornus officinale Sieb, Doc.) and they were extracted with methanol (MeOH), ethyl ether (EtEt), ethyl acetate (EtAc), and also the extract existed in the aqueous layer II (Aq L. II) was used.

• 대한화장품학회:학술대회논문집
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• 대한화장품학회 2003년도 IFSCC Conference Proceeding Book II
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• pp.110-116
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• 2003

We have developed a high performance powder, which has a quenching efficacy not only for short-chain fatty acids and amines, but also for vinyl ketones (l-octen-3-one, cis-l,5-octadien-3-one), newly found as other key compounds in axillary malodor. By investigating various powders known to have a quenching efficacy, we finally developed a highly porous silica bead containing magnesium oxide. We found that the superior deodorant effect performed by this powder was the result of multiple effects due to both an excellent physical adsorption capability from its high porosity and a specific adsorption of vinyl ketones by magnesium in the powder. An antiperspirant formulation containing both this powder and a Morus alba extract showed good efficacy as a deodorant.

• 한국생명과학회:학술대회논문집
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• 한국생명과학회 2000년도 제29회 국제학술심포지움 및 추계학술대회
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• pp.99-99
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• 2000

• 한국생명과학회:학술대회논문집
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• 한국생명과학회 2000년도 제29회 국제학술심포지움 및 추계학술대회
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• pp.100-100
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• 2000

• 한국생명과학회:학술대회논문집
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• 한국생명과학회 2000년도 제29회 국제학술심포지움 및 추계학술대회
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• pp.101-101
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• 2000

• 한국생명과학회:학술대회논문집
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• 한국생명과학회 2000년도 제29회 국제학술심포지움 및 추계학술대회
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• pp.98-98
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• 2000

• 대한화장품학회지
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• 제32권3호
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• pp.181-191
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• 2006

본 연구에서는 제주도에서 자생하는 36종의 식물 추출물에 대한 항산화, 미백 그리고 주름억제 효능을 조사하였다. 항산화 효능은 DPPH (1,1-diphenyl-2-picrylhydrazyl radical)을 이용한 free radical 소거 활성 측정, luminol-의존성 화학발광법을 이용한 $Fe^{3+}-EDTA/H_2O_2$ 계에서 생성된 활성산소종(ROS)의 소거활성 측정, rose-bengal로 증감된 사람 적혈구의 광용혈법을 이용한 세포보호 효과를 측정하였다. 미백 효능 검색으로 tyrosinase 저해활성 측정과 주름개선 효능검색으로 elastase의 저해 활성을 측정하였다. 그 결과 DPPH의 free radical 소거활성은 소리쟁이 전초(Rumex crispus $FSC_{50};\;10{\mu}g/mL$)에서 높게 나타났고, 활성산소 소거활성은 질경이 전초(Plantago asiatica, $OSC_{50};\;0.006{\mu}g/mL$), 소리쟁이 전초($0.04{\mu}g/mL$), 세포보호활성은 $50{\mu}g/mL$ 농도에서 소리쟁이 전초($\tau_{50};\;1,140 min $, 후박나무 잎(Machilus thunbergii, 216 min) 및 노박덩굴 잎/줄기/꽃(Celastrus orbiculatus, 200 min)에서 크게 나타났다. $200{\mu}g/mL$ 농도에서 tyrosinase 저해활성은 뽕나무 줄기(Morus alba, 94.8%), elastase의 저해 작용은 소리쟁이 전초(81.8%), 뽕나무 줄기(74.6%), 노박덩굴 잎/줄기/꽃(63.1%)에서 큰 활성이 나타났다. 결론적으로 소리쟁이, 질경이, 후박나무 잎, 뽕나무 줄기 및 노박덩굴 잎/줄기/꽃 추출물은 기능성 화장품 제조를 위한 원료로 사용하기에 충분한 가능성이 있음을 확인할 수 있었다. 향후 제품화를 위하여 좀더 다양한 연구들이 필요하다고 사료된다.