• 통합자연과학논문집
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• 제1권1호
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• pp.19-23
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• 2008

Morus alba has been well known for its tonic effect or preventing of hypertension, aging, or diabetes mellitus in Asian countries. To evaluate the its effect on hair growth promotion, we performed the hair regrowth experiment with leaf, branch, root and fruit extract of Morus alba on animal model of C57BL/6 mouse. The hair regrowth effect was remarkable in the mouse treated branch and root extract (with what %), however, little effect on hair regrowth appeared on the mouse treated with leaf extract. Morus alba extract displayed antibacterial effects on Bacillus subtilis, Staphylococcus aureus, Pseudomonas and Candida albicans. These results indicated that branch and root extract of Morus alba could be applicable for hair regrowth or prevention of hair loss in human.

• 한국식품영양과학회지
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• 제39권9호
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• pp.1263-1269
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• 2010

상백피의 기능성식품 소재로서의 이용 가능성을 조사하기 위하여 상백피 물 추출물의 항산화 활성 및 in vitro에서의 항천식 효과를 확인하였다. 항산화 측정 결과는 총 페놀함량은 35.2 mg/g로 나타났으며, DPPH radical 소거능은 35.3~59.8%, hydroxyl radical 소거능은 62.1~78.8% 범위로 높은 항산화 효능을 나타내었다. DNP-IgE와 HSA로 활성화된 RBL-2H3 세포에서의 항천식 효과는 농도가 증가할수록 유의적으로 $\beta$-hexosaminidase를 감소시켰으며, 염증성 cytokine인 IL-4, TNF-$\alpha$ 사이토카인 분비량 또한 유의적(p<0.05)으로 감소시켰다. 결과적으로 상백피는 높은 항산화력을 가지며, 항천식과 관련된 지표들을 유의적으로 감소시킴으로써 천식 예방 및 개선을 위한 기능성 소재로서 이용가치가 높을 것으로 사료된다.

• 한국잠사곤충학회지
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• 제6권
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• pp.1-8
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• 1966

각종 조건이 상수의 조장 1,000m당 엽량과 어떠한 관계가 있는가를 조사하였다. 1. 품종과의 관계 각 계통별 평균치에서는 106~109kg로 거의 차가 없으며 엽량의 계층별 분포상황은 Morus bombycis koidz. 계통이 가장 그 폭이 좁아서 60~160kg의 범위내에 있고 Morus Lhou(Ser.) koidz. 계통은 50~170kg, Morus alba L. 계통은 50~180kg의 범위내에 있다. 그러나 전품종의 79%는 80~140kg의 범위내에 있고 특히 Morus Lhou(Ser.) koidz. 계통은 그 85%가 이 범위내에 있다. 그리고 각 계통마다 1~2개의 Peak가 있으니 즉 Morus bombycis koidz.는 80~90kg와 120~140kg의 계층에 가장 많이 분포해 있고, Morus alba L. 계통은 90~100kg, Morus Lhou(Ser.) koidz. 계통은 100~110kg의 계층에 가장 많이 분포해 있다. 2. 정지법과의 관계 근예정지의 85kg에 대해서 다한식정지는 149kg로 근예정지에 비해서 75%가 더 많다. 3. 지조의 벌채정도와의 관계 무벌채구의 140kg에 대해 조장의 1/3벌채구는 166kg, $\frac{1}{2}$벌채구는 188kg로 무벌채구에 비해 각각 19%와 34%가 많았다. 그러나 이와같은 엽량의 증가는 주로 신소엽량중의 신소량의 증가에 기인하였다. 4. 지조의 세태와의 관계 동일 주내에 있어서 세조는 66kg, 중조는 80kg이었으나 유의차는 없었고, 태조는 150kg로 중조에 비해 88%나 더 많았다. 또 조경과의 관계에 있어서도 조경 10cm당 엽량에 있어서 세조는 811g, 중조는 875g이었으나 유의차는 없었고, 태조는 1,461g로 중조에 비해 67%나 더 많았다. 그리고 전지조의 평균은 1,201g이었다.

• 한국식품위생안전성학회지
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• 제10권3호
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• pp.139-145
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• 1995

In order to develop a natural food preservative, the root bark of Morus alba was extracted with several solvents, and then antimicrobial activity was investigated. The optimum extracting condition for the antimicrobial substance from the sample, minimum inhibitory concentration (MIC) of the extracted substance against microorganisms were also examined. The antimicrobial activity of the ethanol extract form the sample was stronger than those of the extracts by the other solvents such as water, methanol. ethyl acetate and acetone. The optimum extracting condition for antimicrobial substance from the sample was shaking extraction twice for 5 hours at room temperature in case of 7 times of absolute ethanol added to the crushed root bark of Morus alba. The ethanol extract from the root bark of Morus alba had strong B. cereus, L. monocytogenes and S. aureus. Especially, Bacillus species was the most susceptible to the extracted substance. The ethanol extract showed antimicrobial activity against Gram negative bacteria(MIC, 160~1600 ug/ml) and yeasts(MIC, 1600 ug/ml) such as C. albicans and S. acidifaeciens. The extract also showed growth inhibition against molds such as A. niger, A. parasiticus, A versicolar and T. viride.

• 한국약용작물학회지
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• 제13권4호
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• pp.146-149
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• 2005

국내에서 재배되고 있는 뽕나무의 resveratrol 및 oxyresveratrol 함유량을 측정한 결과 부위로는 뿌리껍질, 품종으로는 신일 및 수원품종이 가장 많은 resveratrol 및 oxyresveratrol를 함유하는 것으로 나타났다. 따라서 뽕나무로부터 resveratrol 및 oxyresveratrol을 유효성분으로 얻고자 할 때는 신일 및 수원품종의 근피를 사용하는 것이 가장 효과적일 것으로 판단된다.

• 생약학회지
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• 제50권1호
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• pp.53-58
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• 2019

Morus alba fruit contains several anthocyanins and flavonoids like cyanidin-3-O-rutinoside and quercetin-3-O-rutinoside. Extractions from Morus alba fruit were performed with five different compositions of ethanol/water [v/v]. High-Performance Liquid Chromatography (HPLC) was used for the validation and content determination of cyanidin-3-O-rutinoside and quercetin-3-O-rutinoside. The contents of cyanidin-3-O-rutinoside in ethanol extracts (100%, 70%, 40%, 20% and 0%, ethanol/water [v/v]) were 1.150%, 0.822%, 0.749%, 0.663% and 0.597%, respectively. Quercetin-3-O-rutinoside contents of ethanol extracts (100%, 70%, 40%, 20% and 0%, ethanol/water [v/v]) were 0.167%, 0.161%, 0.159%, 0.155% and 0.096%, respectively. The highest contents of cyanidin-3-O-rutinoside and quercetin-3-O-rutinoside were in the ethanol extract with 100% ethanol/water [v/v]. These HPLC analysis method could be used as basic data for standardization of functional food from Morus alba fruit.

• 대한약침학회지
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• 제4권3호
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• pp.93-99
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• 2001

Objective : This study was performed to examine the Herbal Acupuncture decrease the side effect of Bee Venom. Methods: We treated Bee Venom and various Herbal Acupuncture mixed Bee Venom using double blind test to 70th health youth, and checked pain, edema size, CBC, Serum biochemistry and Thermography. Results: 1. Herbal Acupuncture made by Morus bombycis Koidzumi showed good results to decrease the side effect of Bee Venom than any other Herbal Acupuncture. 2. We examined CBC, ESR and Serum biochemistry before and after treated. Special change was not showed. 3. We observed the pain and edema after treated Bee Venom and Morus bombycis Koidzumi Herbal Acupuncture mixed Bee Venom. We knew that Morus bombycis Koidzumi Herbal Acupuncture was decrease the pain and edema due to Bee Venom. 4. According to these clinical studies, Morns bombycis Koidzumi Herbal Acupuncture has a possibility to be a good partner of Bee Venom.

• 펄프종이기술
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• 제38권3호
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• pp.38-46
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• 2006

This study was carried out to investigate the sheet properties of Morus Hanji, made by different pulping methods, such as alkali, alkali-peroxide and sulfomethylated pulping, and different stocks composed to bast and whole stalk fibers. Two species of Morus, M. alba and M. lhou, were used. Pulp yield of the whole stalk parts, its brightness and opacity were higher than those of bast part. In particular sulfomethylated pulp has higher brightness of $62{\sim}63%$, than other pulps(average brightness $30{\sim}40%$). In mechanical properties, paper made of bast fiber has higher strength than those of the whole stalks. Hanji made from M. lhou, whole stalk, and sulfomethylated pulp gave better sheet formation and higher strength than those of the others. Hanji from M. alba bast fiber and whole stalk pulps were not so good sheet properties.

• 한국식품위생안전성학회지
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• 제10권4호
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• pp.225.1-230
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• 1995

The ethanol extract from the root bark of Morus alba showed the strongest antimicrobial activity on the growth of almost all the tested microorganisms which were food-borne pathogens and food-related microorganisms. 1) In order to isolate and purify of antimicrobial substance extracted from the root bark of Morus alba, the antimicrobial substance from the ethanol extract which exhibited a strong antimicrobial activity was purified by solvent fractionation, silica gel column chromatography, TLC and HPLC. Among the fractions fractionated by 4 kind of solvents from the ethanol extract, the antimicrobial activity of ethyl acetate fraction had the strongest antimicrobial activity against B. subtilis. Unknown compound were isolated from the ethyl acetate fraction by silica gel column chromatography, TLC and HPLC and the compounds showed strong absorbance at 207, 217 and 285 nm, therefore, it was supposed to be a kinds of aromatic compound.

• 한국자원식물학회지
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• 제26권3호
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• pp.397-402
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• 2013

Morus Folium (Sang-yeop in Korean) is one of the most important Oriental medicinal plants. In Korea, both M. alba and M. cathayana are regarded as the botanical sources for Morus Folium. In order to discriminate M. alba and M. cathayana from their adulterant, M. tricuspidata, mitochondrial NADH dehydrogenase subunit 7 (nad7) intron 2 region was targeted for molecular analysis with universal primers. DNA polymorphisms, including SNP sites, insertions, and deletions, were detected among these three species sequencing data. Based on these DNA polymorphisms, specific primers were designed for the three species respectively. Multiplex PCR was conducted for molecular authentication of M. alba, M. cathayana, and M. tricuspidata with specific primers. The present results indicate that it is possible to identify Morus Folium from its adulterant using mitochondrial nad7 intron 2 region. The established multiplex-PCR system was proved to be effective for identification of Morus Folium. The results indicate that mitochondrial introns can be used for inter-specific polymorphic study, and the described method can be applied for molecular identification of medicinal materials.