• Journal of Chest Surgery
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• v.21 no.6
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• pp.1124-1136
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• 1988

Massive hemoptysis, usually rapid flooding of tracheobronchial tree and asphyxia, is associated with high mortality. We have controlled massive hemoptysis in two cases with use of bronchial artery angiography & selective bronchial artery embolization with Gelfoam particle. One case was inoperable case that was confirmed as TOF c severe pulmonary artery hypoplasia with massive hemoptysis due to hypertrophied bronchial artery and its collaterals. Another case was congenital ASD with pulmonary Aspergillosis, postop. empyema and BPF associated with massive bleeding due to erosion of hypervascular bronchial artery. We experienced dramatic improvement of general condition and cessation of massive hemoptysis for above two cases. No other problems and complication were noted during postop. hospitalization and follow-up period.

• Journal of Chest Surgery
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• v.18 no.2
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• pp.320-326
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• 1985

Pulmonary sequestration occurs when some disturbance produces a cystic mass of nonfunctioning lung tissue which lacks normal communication with the tracheobronchial tree. Between 1971 and 1985, pulmonary sequestration was diagnosed in 11 patients, ranging age from 3 to 29 years. All sequestration were intralobar type. Definitive diagnosis can only be obtained by aortography and/or surgical exploration in 10 cases. The other one was confirmed by pathologic examination postoperatively. The presenting complaints were mostly recurrent local pulmonary infection, but in 2 cases mediastinal mass with respiratory symptoms was presented, and cardiac murmur was only finding in one case. Preoperative diagnostic procedure revealed 3 associated anomalies which were funnel chest, right aortic arch, and pulmonic stenosis with vascular ring. Operative treatment for sequestration was lobectomy in 10 cases, and a segmentectomy in one. There was no operative mortality, but 3 complications [empyema, B-P fistula, post-op bleeding] which were controlled by subsequent operations or conservative measure. Aortography is strongly advocated not only for its diagnostic value, but for its preoperative localization of the aberrant vessels that are the major concern to the surgeon.

• Proceedings of the Korea Information Processing Society Conference
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• 2022.05a
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• pp.452-455
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• 2022

4차 산업혁명의 확산으로 의학계에서도 딥러닝 기술을 이용한 질병의 치료결과 예측 연구가 활발하다. 이와 관련, 일부 연구에서 국소적인 환자 데이터의 활용으로 인해 도출된 연구 결과의 일반화가 어려웠으며 예측률 제고를 위해 특정 딥러닝 알고리즘을 중심으로 한 실험이 추진되어 다양한 알고리즘별 예측률의 비교·분석 결과를 제시하는 연구도 미흡하였다. 이에, 건강보험심사평가원의 대규모 진료 정보와 다종의 알고리즘을 제공하는 AutoML을 이용, 사망률이 높은 80대·90대 노령자 대상 폐암 진단 후 84개월간의 사망률을 예측하는 Decision Tree 등 5개 알고리즘별 모델을 생성하고 이를 활용, 사망률의 예측 성능을 비교하고 사망률에 영향을 미치는 요인에 대한 분석 결과를 도출하였다.

• Proceedings of the Korean Information Science Society Conference
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• 2012.06c
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• pp.139-141
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• 2012

이 논문에서는 한국인 급성심근경색증 환자에 대한 KAMIR 데이터를 기반으로 ST분절상승 심근경색이 처음 발병한 환자의 사망에 영향을 미치는 위험요소들을 찾고, 이를 기반으로 ST분절상승 급성심근경색환자의 1년 이내 사망을 예측하는 모델을 제시한다. 총 22개의 속성 중에서 속성 선택 알고리즘을 적용한 결과 나이, 심장박출계수, 크레아티닌, 고감도 C-반응성 단백질 등 4개의 속성이 선택되었고, 이 속성들을 이용하여 더욱 정확한 예측 모델을 구축할 수 있었다. 제시된 모델을 통해서 고위험군 환자의 위험성을 평가하고 예후를 추정할 수 있을 것으로 기대한다.

• Korean journal of applied entomology
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• v.48 no.3
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• pp.319-325
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• 2009

Woolly apple aphid, Eriosoma lanigerum, overwintered as adult or nymph stage on rootstocks, and crown- and root sucker in the soil. In an un sprayed apple orchard, the number of E. lanigerum colony started to increase from mid-April, showed the 1st peak between late June and early July, thereafter decreased followed by the 2nd peak in late July, and then again peaked in late September as the size in the 1st peak. In this orchard, the number of E. lanigerum colonies per tree did not exceed 3.5 colonies during the peak occurrence period, and was maintained around 2 colonies throughout seasons. In all seasons, parasitism of Aphelinus mali on E. lanigerum was much lower on root colonies than on aerial colonies that located on shoots and tree trunks above the ground. The parasitism of E. lanigerum was high in most orchards examined, showing parasitism of > 70% in maximum in most cases. In the laboratory bioassay for the mortality effects of several insecticides on E. lanigerum, fenitrothion, dichlorphos, machine oil, methidathion, thiacloprid, and imidacloprid showed 97.8, 96.8, 95.4, 91.5, 26.7, and 7.8% morality, respectively. Also, the adult emergence rates from A. mali mummies were 51.2, 72.6, 14.2, 3.5, 72.2, and 85.4% in the treatment of the above insecticides, respectively. Insecticides belong to neonicotinoid, which are newly developed to control aphids, showed low mortality against E. lanigerum. Fenitrothion and dichlorphos were effective on E. lanigerum control and had a low toxic to A. mali. Consequently, the insecticides should be useful in integrated pest management system for E. lanigerum in apple orchards.

• Korean Journal of Environment and Ecology
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• v.26 no.5
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• pp.675-681
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• 2012

In this experiment, I investigated toxicity evaluation of chemicals using domestic frog embryos, along FETAX (Frog Embryo Teratogenesis Assay-Xenopus) protocol. I investigated $Cu^{2+}$ and Tebuconazole effect on the tree frog, Hyla japonica, embryos by probit analysis. Mortality and malformation rates increased and larval body length decreased depending on the concentrations of $Cu^{2+}$ and Tebuconazole. The teratogenic concentration ($EC_{50}$) of $Cu^{2+}$ and Tebuconazole were 0.05, 5.0mg/${\ell}$, respectively and the embryo lethal concentration ($LC_{50}$) of $Cu^{2+}$ and Tebuconazole were 0.16, 38.5, respectively. The teratogenic index (TI) appeared 3.0 in $Cu^{2+}$ and 7.7 in Tebuconazole, which showed teratogenicity in embryonic development of Hyla japonica. These results reveal that $Cu^{2+}$ and Tebuconazole in this experiment suppressed the development of embryos at relatively low concentration. Much of Hyla japonica embryos can be secured, and easy to incubate. In addition, mortality, malformation ratios, malformation patterns and growth rates are similar to the results from the other assay systems. Therefore, the Hyla japonica embryo teratogenesis assay system could be a useful tool to evaluate toxicity of pollutants in environment.

• Neurospine
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• v.15 no.4
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• pp.329-337
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• 2018

Objective: Machine learning algorithms excel at leveraging big data to identify complex patterns that can be used to aid in clinical decision-making. The objective of this study is to demonstrate the performance of machine learning models in predicting postoperative complications following anterior cervical discectomy and fusion (ACDF). Methods: Artificial neural network (ANN), logistic regression (LR), support vector machine (SVM), and random forest decision tree (RF) models were trained on a multicenter data set of patients undergoing ACDF to predict surgical complications based on readily available patient data. Following training, these models were compared to the predictive capability of American Society of Anesthesiologists (ASA) physical status classification. Results: A total of 20,879 patients were identified as having undergone ACDF. Following exclusion criteria, patients were divided into 14,615 patients for training and 6,264 for testing data sets. ANN and LR consistently outperformed ASA physical status classification in predicting every complication (p < 0.05). The ANN outperformed LR in predicting venous thromboembolism, wound complication, and mortality (p < 0.05). The SVM and RF models were no better than random chance at predicting any of the postoperative complications (p < 0.05). Conclusion: ANN and LR algorithms outperform ASA physical status classification for predicting individual postoperative complications. Additionally, neural networks have greater sensitivity than LR when predicting mortality and wound complications. With the growing size of medical data, the training of machine learning on these large datasets promises to improve risk prognostication, with the ability of continuously learning making them excellent tools in complex clinical scenarios.

• Korean journal of applied entomology
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• v.60 no.4
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• pp.463-471
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• 2021

As a tropical plant, the neem tree (Azadirachta indica) has been used for a long time for disease and pest control and medical purposes. In this paper, we reviewed for the active ingredient of neem, the mode of action of azadirachtin in terms of insect growth regulation, repellent, feeding inhibition and oviposition against plant pests. And also we reviewed the current status of practical use in Korea. Among 57 products of neem-based eco-friendly organic agricultural materials distributed in Korea, seven products were certified for their efficacy. The average azadirachtin content of the seven products was 0.38%, which was 5.5 times less than the average content of 2.1% distributed worldwide. In the control effect on neem products in Korea, it showed some variation on aphids, but most showed a control effect of more than 90%. The treatment effects of Lycorma delicatula nymphs were 73-77%, and the control effects for thrips were obtained in the range of 50-72% mortality. The mortality effects against bug and moth species were generally low. It is expected that this review would provide important information necessary for the understanding of distributed neem products and the interpretation of experimental data.

• Asian Journal of Turfgrass Science
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• v.18 no.4
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• pp.193-200
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• 2004

Environmentally sound control of fall webworm, Hyphanria cunea (Drury) with entomopathogenic nematode, Sreinernema carpocapsae Pocheon strain was evaluated in the laboratory and pot. Pathogenicity of 5. carpocapsae Pocheon strain was different depending on larval stage, i.e., mortality of the 2nd instar and the $3\~4th$ instar was $100\%$ with >20 infective juveniles (Ijs)/larva in 3 days, but the 5th instar was $34\%$ with (Ijs)/larva in 3 days. Pathogenicity of 5. carpocapsae Pocheon strain was higher with increasing nematode concentration. Mortality of Hyphanria cunea larva by 5. carpocapsae Pocheon strain was not significantly different (more than $70\%$) between nematode concentration on treated trees (Malus alba and Platanus orientalis) and in pot.

• Korean Journal of Poultry Science
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• v.46 no.4
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• pp.263-269
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• 2019

Infectious bronchitis virus (IBV) is an acute respiratory disease, causing economic losses in poultry production. IBV commonly manifests respiratory disease symptoms and poor egg quality in poultry, affecting overall performance of both broilers and layers. IBV infection further predisposes poultry to secondary opportunistic bacterial infections. IBV undergoes rapid genetic evolution resulting in various new strains. There is no cross protection among IBV serotypes which makes full protection against wild-type IBV virtually impossible. In this study, recently isolated IBVs (K24/18, K29/18, K183/18) from Korean broiler farms were genetically analyzed based on S1 gene. According to the results, IBV isolates showed highest homology with QX-IBV. However, phylogenetic tree analysis revealed that isolates were divided into distinct sub-clusters within QX-IBV. To determine pathogenicity of IBV, day-old chicks were challenged with IBV through ocular route. After challenging the chicks, we executed microscopic examination, virus detection in their organs, and observation of clinical signs and mortality. We found that the K24/18, K29/18, K183/18 challenge groups showed 28%, 57%, and 42% mortality, respectively, with high microscopic trachea lesion scores, indicating that these QX-IBV-like strains are pathogenic to chicks and can therefore be a threat to poultry production.