• Title/Summary/Keyword: Morphological instability

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Lateral Migration Features of the Alluvial Channels in Hapyeong Intake Station, Nakdong River (해평취수장 부근에서 충적하천의 저수로 이동 특성)

  • Jang, Chang-Lae;Lee, Gang-Man;Kim, Gye-Hyun
    • Journal of Korea Water Resources Association
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    • v.41 no.4
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    • pp.395-404
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    • 2008
  • It is important to understand the complex, various migration features of the alluvial channels for river engineering. In this study, the morphological changes and migration features of alluvial channels were investigated by analyzing the aerial photographs of active channels between 1972 and 2004 in Hapyeong Intake Station, Nakdong river. The lower channels were migrated from left bank to right bank and showed the features of braided channel in 2004. The instability of lower channels was increased due to the increased channel slope and width. The sinuosity of lower channels was decreased with time. As time increased, the increasing rate of lower channel and lateral migration rate were decreased. As a result of meso-scale regime analysis by using bankfull discharge, multiple row bars were developed, and suspended sediment load was governed in the flow as a sand bed channel.

Snapping Knee due to Impingement between Atypical Wrisberg Ligament and Expanded Anterior Cruciate Ligament - Report of One Case - (비전형적 리스버그인대와 비후된 전방십자인대의 충돌에 의한 탄발음 -1례 보고-)

  • Kang, Jae Do;Kim, Hyung Chun;Lee, Gi Jun
    • Journal of the Korean Arthroscopy Society
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    • v.2 no.2
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    • pp.168-172
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    • 1998
  • Discoid lateral menisci were common morphological anomaly and several classifications were proposed. Watanabe et al classified all discoid menisci, as seen arthroscopically, into three types 1) complete 2) incomplete and 3) Wrisberg ligament type. The purpose of this study is to report a rare case of both painful snapping knee joints in 6 year-old female. On arthroscopic examination, complete lateral discoid meniscus which consisted of taut Wrisberg ligament and intact tibial insertion of posterior horn was found, and abnormal anterior cruciate ligament(ACL) which has expanded femoral origin over the posterior articular surface of lateral femoral condyle was also found. At the time of arthroscopic surgery, hypertrophied high-riding Wrisberg ligament was resected, and expanded femoral origin of the anterior cruciate ligament was partially resected nearly to normal margin, and discoid lateral meniscus was saucerized. After these procedures, abnormal snapping sound was disappeared in full range of motion. On the follow-up examination after 1 year, pain and snapping sound were disappeared and any instability and limping were not found.

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Apoptosis-inducing Effect of Fructus Trichosanthis in HL-60 Leukemic Cells (백혈병 세포주 HL-60에서 과루실 세포고사 유도 효과)

  • Kwon Kang Beom;Kim Eun Kyung;Han Mi Jeong;Ryu Do Gon
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.19 no.4
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    • pp.903-907
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    • 2005
  • Many naturally occurring plant extracts are studied for their beneficial effects for health and particularly on cancer. Apoptosis, or programmed cell death, occurs in both normal and pathological conditions, including cancer Dysregulation of apoptosis allows transformed cells to continually and uninhibitedly enter the cell cycle, thus perpetuating the sequence of mutation, genomic instability and, finally, oncogenesis. To investigate the apoptosis-inducing effect of the extract of Fructus Trichosanthis (EFT) on leukemic HL-60 cells and its mechanism, HL-60 cells in vitro in culture medium were given different doses of the extract. The inhibitory rate of cells were measured by microculture tetrazolium assay, cell apoptotic rate was detected by flow cytometry, morphology of cell apoptosis was observed by DAPI fluorescence staining, and the activations of caspases and PARP were detected using Western blotting analysis. The extract could activate the caspase-3 and caspase-8, induce PARP cleavage, inhibit growth of HL-60 cells, and cause apoptosis significantly The suppression was in dose-dependent manner. Marked morphological changes of cell apoptosis including condensation of chromatin and nuclear fragmentation were observed clearly by DAPI fluorescence staining especially. These results will provide strong laboratory evidence of EFT for clinical treatment of acute leukemia.

Fabrication and Characterization of Polycrystalline Mereuric Iodide Films using Particle-in-Binder Methods (Particle-in-Binder(PIB) 법을 이용한 다결정 $HgI_2$ 필름 제작 및 특성 연구)

  • Cha, Byung-Youl;Cho, Sung-Ho;Kim, So-Yeong;Woon, Min-Seuk;Nam, Sang-Hee
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2007.06a
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    • pp.330-330
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    • 2007
  • Polycrystalline mercuric iodide $HgI_2$) films are being developed as a new detector technology for digital x-ray imaging. The $HgI_2$ is generally vacuum deposited by physical vapor deposition (PVD) process. But the PVD thick deposition has been caused any instability in the biasing due to any defects or cracks. In this work we present a new particle-in-binder (PIB) methodologies used for the $HgI_2$ thick films. These growth techniques can be easily extended to produce much larger film areas. This paper, for the first time, presents results and comparison of polycrystalline $HgI_2$ films derived by various PIB methods. We investigated the structural and morphological properties of the films using X-ray diffraction (XRD) and scanning electron microscopy (SEM) analysis. The films were characterized with respect to their electrical properties and in response to x-ray photons. Physical and electrical results were also compared between conventional polycrystalline PVD and our detectors. Leakage current as low as $350\;pA/cm^2$ at the bias voltage of ~ 200 V has been observed. And high sensitivity and good linearity in the response to x-rays was obtained in the film derived by PIB sedimentation method. Our future efforts will concentrate on optimization of film growth techniques for uniform large area deposition on image readout arrays.

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Apoptosis-inducing Effect of Fructus Trichosanthis in HL-60 Leukemic Cells (백혈병 세포주 HL-60에서 과루실(瓜蔞實)의 세포고사 유도 효과)

  • Kwon, Kang-Beom;Kim, Eun-Kyung;Han, Mi-Jeong;Ryu, Do-Gon
    • The Journal of Traditional Korean Medicine
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    • v.15 no.1
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    • pp.83-89
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    • 2006
  • Many naturally occurring plant extracts are studied for their beneficial effects for health and particularly on cancer. Apoptosis, or programmed cell death, occurs in both normal and pathological conditions, including cancer. Dysregulation of apoptosis allows transformed cells to continually and uninhibitedly enter the cell cycle, thus perpetuating the sequence of mutation, genomic instability and, finally, oncogenesis. To investigate the apoptosis-Inducing effect of the extract of Fructus Trichosanthis (EFT) on leukemic HL-60 cells and its mechanism, HL-60 cells in vitro in culture medium were given different doses of the extract. The inhibitory rate of cells were measured by microculture tetrazolium assay, cell apoptotic rate was detected by flow cytometry, morphology of cell apoptosis was observed by DAPI fluorescence staining, and the activations of caspases and PARP were detected using Western blotting analysis. The extract could activate the caspase-3 and caspase-8, induce PARP cleavage, inhibit growth of HL-60 cells, and cause apoptosis significantly. The suppression was in dose-dependent manner. Marked morphological changes of cell apoptosis including condensation of chromatin and nuclear fragmentation were observed clearly by DAPI fluorescence staining especially. These results will provide strong laboratory evidence of EFT for clinical treatment of acute leukemia.

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HI gas kinematics of paired galaxies in the cluster environment from ASKAP pilot observations

  • Kim, Shin-Jeong;Oh, Se-Heon;Kim, Minsu;Park, Hye-Jin;Kim, Shinna
    • The Bulletin of The Korean Astronomical Society
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    • v.46 no.2
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    • pp.70.1-70.1
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    • 2021
  • We examine the HI gas kinematics and distributions of galaxy pairs in group or cluster environments from high-resolution Australian Square Kilometer Array Pathfinder (ASKAP) WALLABY pilot observations. We use 32 well-resolved close pair galaxies from the Hydra, Norma, and NGC 4636, two clusters and a group of which are identified by their spectroscopy information and additional visual inspection. We perform profile decomposition of HI velocity profiles of the galaxies using a new tool, BAYGAUD which allows us to separate a line-of-sight velocity profile into an optimal number of Gaussian components based on Bayesian MCMC techniques. Then, we construct super profiles via stacking of individual HI velocity profiles after aligning their central velocities. We fit a model which consists of double Gaussian components to the super profiles, and classify them as kinematically cold and warm HI gas components with respect to their velocity dispersions, narrower or wider 𝜎, respectively. The kinematically cold HI gas reservoir (M_cold/M_HI) of the paired galaxies is found to be relatively higher than that of unpaired control samples in the clusters and the group, showing a positive correlation with the HI mass in general. Additionally, we quantify the gravitational instability of the HI gas disk of the sample galaxies using their Toomre Q parameters and HI morphological disturbances. While no significant difference is found for the Q parameter values between the paired and unpaired galaxies, the paired galaxies tend to have larger HI asymmetry values which are derived using their moment0 map compared to those of the non-paired control sample galaxies in the distribution.

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Dynamic Morphologic Study of the Ulnar Nerve Around the Elbow Using Ultrasonography (초음파를 이용한 주관절 주위 척골 신경의 동적 형태학적 연구)

  • Jeon, In-Ho;Lee, Seong-Man;Choi, Jin-Won;Kim, Poong-Tak
    • Clinics in Shoulder and Elbow
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    • v.10 no.1
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    • pp.99-105
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    • 2007
  • Purpose: The morphological study and dynamic stability of the ulnar nerve around the elbow joint was investigated in asymptomatic normal population using ultrasonography. The purpose of this study is to provide fundamental data for ultrasonographic diagnosis of ulnar neuropathy in cubital tunnel syndrome. Materials and Methods: Fifty cases of 25 healthy male volunteers, aged between 20 to 30 years, included in this study. High resolution 7.5 MHz linear probe was used to examine the ulnar nerve in axial and longitudinal views. In a longitudinal view, the course, position and the thickness of nerve were monitored, the diameter of ulnar nerve and dynamic stability at elbow flexion and extension were measured in an axial view at four different points; 1cm proximal to medial epicondyle, behind the medial epicondyle, entrance to Osborne ligament, and 1cm distal to Osborne ligament. Results: The short diameters of ulnar nerve at elbow extension at four anatomic points were 2.66 mm, 2.97 mm, 2.64 mm, and 2.69 mm and the long diameters were 4.61 mm, 4.56 mm, 4.36 mm, and 4.37 mm, which showed no significant change at each point. However, at elbow flexion, the short diameters were changed to 2.72 mm, 2.34 mm, 2.65 mm, and 2.41 mm and the long diameters into 4.49 mm, 5.40 mm, 4.16 mm, and 4.66 mm. At elbow flexion, significant morphologic change was observed in the medial epicondyle area, and the diameter of the ulnar nerve was shortest at the entrance of Osborne ligament both at flexion and extension. In terms of dynamic stability, nine subluxations and seven dislocations were observed. Conclusion: This study shows dynamic instability and a morphological change of long and short diameters of ulnar nerve at flexion and extension in a normal person, which should be considered in the ultrasonographic diagnosis of ulnar neuropathy.

Preparation of $PES-TiO_2$ Hybrid Membranes and Evaluation of Membrane Properties ($PES-TiO_2$ 복합막의 제조 및 막 특성 평가)

  • Youm, Kyung-Ho;Lee, Mi-Sheon
    • Membrane Journal
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    • v.17 no.3
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    • pp.219-232
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    • 2007
  • The polyethersulfone(PES)-titanium oxide($TiO_2$) hybrid membranes were prepared by immersion precipitation phase inversion method. The casting solution for the preparation of $PES-TiO_2$ hybrid membrane was provided by adding $TiO_2$ nano particles into the basis polymer solution of 14 wt% and 20 wt% PES/N-methyl-2-pyrrolidone(NMP). The $TiO_2$ loading [wt% ($TiO_2/NMP$)] in eating solution was varied from 0 to 60 wt%. Membrane performance and morphological change of the resulting $PES-TiO_2$ hybrid membranes were discussed in aspect of $TiO_2$ loading, by viscosity, coagulation value and light transmittance of the casting solution, measurement of tensile strength, pore size and contact angle, surface and cross sectional SEM images of the hybrid membrane, and ultrafiltration experiments using the hybrid membrane. According as increase of $TiO_2$ loading in the casting solution, viscosity is increased and coagulation value becomes lower, therefore the thermodynamic instability of the casting solution is increased. It is found that when $TiO_2$ loading is increased, 1) precipitation rate becomes faster while instantaneous demixing is maintained, 2) pure water flux, membrane pore size and compaction stability of the resulting membranes are increased, 3) tensile strength and contact angle are decreased. Dead-end ultrafiltration of bovine serum albumin(BSA) solution using the hybrid membrane shows that membrane performance(flux of BSA solution) enhanced up to 7 times compared with the results obtained using the pure PES membrane(not containing $TiO_2$ particle), due to the increase of hydrophilicity.