• 제목/요약/키워드: Morphological and Mechanical Characteristics

검색결과 81건 처리시간 0.021초

전신진동이 골다공증이 유발된 쥐 해면골에 미치는 영향 - 골다공증 치료제 효과와 비교 (Effect of Whole Body Vibration on Osteoporotic Trabecular Bone of Rats - Compared with the Effect of Actonel)

  • 고창용;이태우;우대곤;김효선;김한성;이법이;임도형
    • 한국정밀공학회지
    • /
    • 제25권5호
    • /
    • pp.148-154
    • /
    • 2008
  • Pharmacotherapy was mainly used to treat osteoporosis. However, some researches showed that pharmacotherapy could induce unexpected adverse effects. Some studies showed that whole body vibration affected beneficially osteoporosis. This paper studied the effect of whole body vibration fur osteoporosis compared with the effect of pharmacotherapy. 10 female rats were used and allocated into 4 group, CON, SHAM, DRUG, and WBV. Rats except SHAM group were ovariectomised to induce osteoporosis. Rats in WBV group were stimulated in whole body vibration at magnitude of $1mm_{peak-peak}$ and frequency 45Hz, for 8 weeks (30 min/day, 5 days/week). Rat in DRGU group was orally administered the Actonel (0.58mg/Kg), for 8 weeks (5days/week). The $4^{th}$ lumbar in rats were scanned at a resolution of $35{\mu}m$ at baseline, before stimulation, and 8 weeks after stimulation by In-vivo micro computed tomography. For detecting and tracking changes of biomechanical characteristics (morphological and mechanical characteristics) in lumbar trabecuar bone of rats, structural parameters were measured and calculated from acquiring images and finite element analysis was performed. In the results, loss of quantity and change of structure of trabecular bone in WBV group were smaller than those in both CON and SHAM groups. In addition, mechanical strength in WBV group was stronger than that in both CON and SHAM groups. In contrast, biomechanical characteristics in WBV group were similar with those in DRUG group. These results showed that reasonable whole body vibration was likely to treat osteoporosis and be substituted partly for drug treatment.

Classification and visualization of primary trabecular bone in lumbar vertebrae

  • Basaruddin, Khairul Salleh;Omori, Junya;Takano, Naoki;Nakano, Takayoshi
    • Advances in biomechanics and applications
    • /
    • 제1권2호
    • /
    • pp.111-126
    • /
    • 2014
  • The microarchitecture of trabecular bone plays a significant role in mechanical strength due to its load-bearing capability. However, the complexity of trabecular microarchitecture hinders the evaluation of its morphological characteristics. We therefore propose a new classification method based on static multiscale theory and dynamic finite element method (FEM) analysis to visualize a three-dimensional (3D) trabecular network for investigating the influence of trabecular microarchitecture on load-bearing capability. This method is applied to human vertebral trabecular bone images obtained by micro-computed tomography (micro-CT) through which primary trabecular bone is successfully visualized and extracted from a highly complicated microarchitecture. The morphological features were then analyzed by viewing the percolation of load pathways in the primary trabecular bone by using the stress wave propagation method analyzed under impact loading. We demonstrate that the present method is effective for describing the morphology of trabecular bone and has the potential for morphometric measurement applications.

프랙탈 파라미터에 의한 마멸분 형태특징 분석 (Analysis of Shape Characteristics of Wear Particles with Fractal Parameters)

  • 조연상;김영희;박흥식
    • 한국기계가공학회지
    • /
    • 제7권4호
    • /
    • pp.109-114
    • /
    • 2008
  • The fractal dimension aims to quantitatively define the irregular characteristics of the shape in nature. It can be useful in describing morphological characteristics of various wear particles. This paper was undertaken to diagnose failure condition for sliding members in lubrication using fractal dimension. The experiments were undertaken to analyze the shape of wear particles and to diagnose failure condition for sliding members in lubrication using the image processing and the fractal parameters. It was possible to diagnose wear mechanism, friction, and damage state of machines through analysis of shape characteristics for wear particle in driven condition using fractal parameters.

  • PDF

브러싱 자극 토마토 공정묘의 지상부와 지하부 생육 변화 (Changes in Shoot and Root Growth of Tomato Seedlings Stimulated by Brushing)

  • 정현우;황희성;황승재
    • 생물환경조절학회지
    • /
    • 제32권3호
    • /
    • pp.205-209
    • /
    • 2023
  • 기계적 자극은 식물체의 형태적 변화를 유도하는 것으로 알려져 있다. 본 연구에서는 기계적 자극을 적용한 토마토의 육묘기 동안의 생육 변화를 확인하기 위해 수행되었다. 브러싱 처리가 기계적 자극으로 이용되었으며, 아크릴이 부착된 이송장치를 이용하여 2시간 간격으로 파종 후 10일 이후부터 처리를 진행하였다. 브러싱 처리 동안 생육 변화를 확인하기 위해 3일 간격으로 생육을 조사하였다. 초장과 엽면적은 브러싱 처리에서 대조구에 비해 감소하는 결과를 보였으며 지상부의 생체중과 건물중은 대조구와 유사한 값을 보였다. 총 근장과 지하부 표면적은 브러싱 처리에서 대조구에 비해 증가하였으며, 지하부 부피는 대조구와 브러싱 처리가 유사한 값을 보였다. 결론적으로 토마토 공정묘에 브러싱 처리는 지상부의 생육 감소를 유도하였으며 지하부의 형태적 발달을 증가시키는 것으로 판단된다.

윤활유 중지 마멸입자의 프랙탈 형상특징 추출 방법 (Extraction of Fractal Shape Characteristics of Wear Particles in Lubricant)

  • 박흥식;우규성;조연상;김동호;예규현
    • Tribology and Lubricants
    • /
    • 제22권5호
    • /
    • pp.276-281
    • /
    • 2006
  • The fractal dimension is quantitatively to define the irregular characteristic of the shape in natural. It can be useful in describing morphological characteristics of various wear particles. This paper was undertaken to diagnose failure condition for sliding members in lubrication by fractal dimension. It will be possible to diagnose wear mechanism, friction and damage state of machines through analysis of shape characteristics for wear particle on driving condition by fractal parameters. In this study, the calculating and analyzing methods of fractal dimensions were constructed for the condition monitoring and wear particle analysis in lubricant condition. So, we carried out the Friction and wear test with the ball on disk type tester, and the fractal parameters of wear particle in lubricated conditions were calculated. Fractal parameters were defined as texture fractal dimension ($D_{t}$), structure fractal dimension ($D_{s}$) and total fractal dimension (D).

Characterization of the complete mitochondrial genome of Mauritian sardinella, Sardinella jussieu (Lacepède, 1803), collected in the Banten Bay, Indonesia

  • Sektiana, Sinar Pagi;Andriyono, Sapto;Kim, Hyun-Woo
    • Fisheries and Aquatic Sciences
    • /
    • 제20권10호
    • /
    • pp.26.1-26.9
    • /
    • 2017
  • Fishes in genus Sardinella are small pelagic species, which plays an important role in marine ecosystem as the first consumer. Those species are also commercially important, whose total catch reaches 278,600 tons in 2011 in Indonesia, but their identification has been difficult for their morphological similarity. In this study, we reported Sardinella jussieu for the first time in Indonesian coastal area (Banten Bay, Indonesia, $6^{\circ}\;0^{\prime}\;50.00^{{\prime}{\prime}}\;S-106^{\circ}\;10^{\prime}\;21.00^{{\prime}{\prime}}\;E$). We were able to confirm the species by both its morphological characteristics including the black spot at dorsal fin origin, the dusky pigmentation at caudal fin, 31 total scute numbers, and DNA sequence identity in the GenBank database by the molecular analysis. Its total mitochondrial genome was determined by the combination of next-generation sequencing and typical PCR strategy. The total mitochondrial genome of Sardinella jussieu (16,695 bp) encoded 13 proteins, 2 ribosomal RNAs, 22 transfer RNAs, and the putative control region. All protein-coding genes started with ATG and typical stop codon and ended with TAA or TAG except for ND4 in which AGA is used. Phylogenetic analyses of both COI region and full mitochondrial genome showed that S. jussieu is most closely related to Sardinella albella and Sardinella gibbosa

Structure -Properties Relations of Polypropylene/ Liquid Crystalline Polymer Blends

  • Sahoo, N.G.;Das, C.K.;Jeong, Hye-Won;Ha, Chang-Sik
    • Macromolecular Research
    • /
    • 제11권4호
    • /
    • pp.224-230
    • /
    • 2003
  • The blends of polypropylene (PP) with glass filled thermotropic liquid crystalline polymer (LCP-g) have been prepared by melt mixing techniques at different blend ratios. The thermal, dynamic mechanical, crystalline and morphological characteristics of these blends were investigated. Higher percent crystallinity was observed for 10% level of LCP-g in the blend in comparison to that of other blend ratios. The thermal stability increased with LCP-g concentration in the blend with PP. The variation of storage modulus, stiffness and loss modulus as a function of blend ratios suggested the phase inversion at the 50% level of LCP-g in the blend. The scanning electron microscopy (SEM) photographs showed the creation of voids and destruction of the fiber structures during the dynamic mechanical measurements. Processing behavior of the blends depended on the fiber forming characteristics of LCP-g, which again varied with the molding temperatures.

New Approach to Investigate the Dynamic Relaxaton Process of Complex Peak in Mechanical and dielectric Characteristics of Anelastic Solids

  • Kim, Bong-Heup
    • E2M - 전기 전자와 첨단 소재
    • /
    • 제11권10호
    • /
    • pp.1-5
    • /
    • 1998
  • Complex dynamic relaxation processes of mechanical as well as dielectric character in polymeric anelastic solids are closely related through the movement of molecular chain segment in morphological structure, and the morphology can easily be modified by the treatments such as mechanical drawing or irradiation, those of which result, in turn, the complicated change on the appearance of the observed complex relaxation peak. In order to extract any meaningful understanding from the modified appearance of the peak, the relaxation peak must be resolved into the sum of the dynamic single relaxation peaks, each of which can be characterized respectively by three factors such as activation energy, magnitude of peak height and peak point temperature on the temperature dependent characteristics.

  • PDF

An Evaluation Method for Three-Dimensional Morphologies of Discontinuities considering the Shear Direction

  • Zhang, Qingzhao;Luo, Zejun;Pan, Qing;Shi, Zhenming;Jang, Bo-An
    • 지질공학
    • /
    • 제32권1호
    • /
    • pp.85-99
    • /
    • 2022
  • Rock discontinuities, as weak interfaces in rock, control mechanical properties of rock mass. Presence of discontinuities complicates the engineering properties of rock, which is the root of anisotropy and heterogeneity that have nonnegligible influences on the rock engineering. Morphological characteristics of discontinuities in natural rock are an important factor influencing the mechanical properties, particularly roughness, of discontinuities. Therefore, the accurate measurement and characterization of morphologies of discontinuities are preconditions for studying mechanical properties of discontinuities. Taking discontinuities in red sandstone as research objects, the research obtained three-dimensional (3D) morphologies of discontinuities in natural rock by carrying out 3D morphological scanning tests. The waviness and roughness were separated from 3D morphologies of rock discontinuities through wavelet transform. In addition, the calculation method for the overall slope root mean square (RMS) as well as slope RMSs of waviness and roughness of 3D morphologies of discontinuities considering the shear direction was proposed. The research finally determined an evaluation method for 3D morphologies of discontinuities by quantitatively characterizing 3D morphologies with the mean value of the three slope RMSs.

Primary Culture of Human Hepatocytes from Small Size Sample

  • Oh, Goo-Taeg;Ahn, Chang-Joon;Ahn, Byung-Min;Hyun, Byung-Hwa;Choi, Jae-Yoon;Kim, Hwan-Mook
    • Toxicological Research
    • /
    • 제8권2호
    • /
    • pp.285-302
    • /
    • 1992
  • Human and rat hepatocytes were isolated by nonperfusion method and cultured for longer than 5 days. Human liver biopsy sample and rat liver were used as hepatocyte source. Several physical and chemical factors which were influencing on hepatocyte isolation procedure were examined and a batch isolation procedure was established for small size sample of rat liver. Isolated hepatocytes showed normal morphlologica characteristics in microscopy and electron microscopical examinations and a morphologica response to phalloidin. Isolated cells were cultured as a monolayer and proven to have intact morphological characteristics for longer than 15 days. Because human liver sample is harder and tighter compared with rat liver, a standard procedure for rat hepatocytes was slightly modified to reduce mechanical damage. Similarly with rat hepatocytes, isolated human hepatocytes showed a normal morphological characteristics and could be cultured for longer than 15days. Human and rat hepatocytes were examined on their functional integrities including cytochrome-P450 related enzyme activity and it's inducibility, hormonal inducibility of AIB uptake and TAT activity, albumin synthesis, DNA synthesis, cellular protein maintenance. In all parameters used in the present study, human and rat hepatocytes showed normal functional characteristics.

  • PDF