• Title/Summary/Keyword: Morphologic

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Corrected transposition of the great arteries: surgical treatment of associated anomalies (교정형 대혈관전위증동반된 심혈관기형의 수술요)

  • Kim, Gi-Bong;No, Jun-Ryang;Seo, Gyeong-Pil
    • Journal of Chest Surgery
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    • v.17 no.3
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    • pp.371-380
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    • 1984
  • Corrected transposition of the great arteries [C-TGA] is one of the rare congenital heart disease in which there is both a discordant atrioventricular relationship and transposition of the great vessels. With this arrangement, systemic venous blood passes through the right atrium into the morphologic left ventricle and out the pulmonary artery. Pulmonary venous blood returns to the left atrium, flows into the morphologic right ventricle and out the aorta. Thus, in the rare case when no additional cardiac anomaly is present, a hemodynamically normal heart exists. But more often they are symptomatic as a result of one or several of the commonly associated defects. This paper describes 13 patients who underwent repair of one or more cardiac anomalies associated with corrected transposition at SN UH, from June 1976 through June 1984. 1.8 were males and 5 females, with ages ranging from 3 years to 27 years. 2. Segmental anatomy was {S,L,L} in 12, or {I,D,D} in 1. 3.Associated anomalies were ventricular septal defect in 10, pulmonary outflow tract obstruction in 6, tricuspid insufficiency in. 4, atrial septal defect in 3, subaortic stenosis in 1, mitral insufficiency in 1, and patent ductus arteriosus in 1. 4.None had complete heart block preoperatively, and 3 developed complete heart block intraoperatively. But one of them recovered sinus rhythm on the postoperative 7th day spontaneously. 5.There were 3 cases of hospital morality. But there was no morality since Dec. 1980. 6.Patients with single ventricle, hypoplastic ventricle or those who had palliative surgery alone are not included in this review.

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Morphologic Change of Rat Liver Induced by Repeated Administration of Carbon Tetrachloride and Dimethylnitrosamine (사염화탄소와 Dimethylnitrosamine의 반복투여가 백서간의 형태학적 변화에 미치는 영향)

  • Lee, Tae-Sook
    • Journal of Yeungnam Medical Science
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    • v.4 no.1
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    • pp.89-96
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    • 1987
  • Carbon tetrachloride and Dimethylnitrosamine, both potent hepatotoxic agents, affect the hepatic lobules with fatty changes and central necrosis, and hemorrhagic necrosis. To study the effects on morphologic changes of the hepatic lobules in cases of single and repeated treatment of both hepatotoxins, sublethal doses of carbon tetrachloride, 0.4ml/kg, and dimethylnitrosamine, 40mg/kg of rats were given intraperitoneally single, twice and triple. With interval of 3 days, and the results were as follows : 1. The fatty changes and central necrosis of the hepatic lobules were milder and more quickly disappeared in the rats with twice or triple treatment than single administration of carbon tetrachloride, and regenerative changes of hepatic and sinusoidal cells achieved fater in the rats with repeated administration of carbon tetrachloride than those with single treatment. 2. The hemorrhagic necrosis of the hepatic lobules was not significantly influenced by the times of DMN treatment, but the hyperplastic changes showed more active to animals, with multiple administration of DMN.

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The Comparison of Triladyl and LEY for Cryosurvival Improvement of Sperm Separated by Percoll in Miniature Pig (Percoll 분리된 미니돼지 정액에서 LEY와 Triladyl을 이용한 동결융해후의 정자 성상 비교)

  • Lee, Sang-Hee;Yoo, Han-Jun;Lee, Yong-Seung;Cheong, Hee-Tae;Yang, Boo-Keun;Kim, Dae-Young;Park, Choon-Keun
    • Reproductive and Developmental Biology
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    • v.34 no.1
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    • pp.41-46
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    • 2010
  • The objective of this study was to evaluated the efficiency of sperm cryosurvival using each extenders Triladyl and LEY containing egg yolk to the cryopreservation of separated sperm by percoll in miniature pig. The ejaculated semen from miniature pig was separated by 65% percoll and un-separated sperm as a control before freezing. The freezing of diluted semen added with Triladyl containing egg yolk and LEY solution (solution I: 11% Lactose or Triladyl + egg yolk; solution II: solution I + glycerol + OEP). Analysis of sperm ability was estimated by viability, capacitation acrosome reaction using chlortetracycline (CIC) the morphologic abnormality and hypoosmotic swelling test(HOST). The groups were designed that as separated sperm by Percoll with Triladyl(ST) or LEY(SL) for cryopreservation. And unseparated sperm with Triladyl(UT) or LEY(UL). As a results, the viability was higher significantly(p<0.05) in ST, SL, UT than UL extender. The morphologic abnormality was measured significantly (p<0.05) lower in ST than other extenders. The AR-patterned in CTC analysis was measured significantly(p<0.05) lower in SL and UL than other extenders. In conclusion, using Triladyl extender resulted in viability and morphology of separated sperm by percoll that were effective than using LEY extender, but it resulted in capacitation acrosome reaction was lower than using LEY extender.

A Study on the Facial Morphologic Characteristics of Mongolian according to Sasangin : Pilot Study (몽골인의 사상체질별 안면부 특징 : 예비 연구)

  • Lee, Jun-Hee;Kim, Kyung-Su;Lee, Gab-Su;Yoo, Jung-Hee;Moon, Young-Sik;Bazargarid, Luvsannyam;Tumurbaatar, N.;Oldokh, S.;Sukhbaatar, Tubdengiin;Kim, Jong-Yoel;Lee, Si-Woo;Kim, Hyo-Jung;Hwang, Min-Woo;Koh, Byung-Hee;Lee, Eui-Ju
    • Journal of Sasang Constitutional Medicine
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    • v.19 no.3
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    • pp.62-74
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    • 2007
  • 1. Objectives This study is a pilot study to investigate the Mongolian's morphologic characteristics of face according to Sasang Constitution. 2. Methods We had collected 100 cases of Mongolian and took pictures their frontal view, lateral view of face and measured height, breaths and projected length of face with Face Features Measurement Program(FFMP) and analyzed shape differences of face according to Sasang constitution. 3. Results and Conclusions (1) In the frontal view of female, there were 11 items(total 322 items) significantly different among three constitutions, and in lateral view 13 items(total 191 items). (2) In the frontal view of male, there were 88 items(total 322 items) significantly different among three constitutions, and in lateral view 46 items(total 191 items).

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Analysis of the Postaxial Polydactyly of the Foot (족부 축후성 다지증의 분석)

  • Lee, Ho-Seung;Yoon, Jun-O;Won, Choong-Hee;Kim, Yong-Min;Choi, Eu-Sung;Kim, Jong-Pil
    • Journal of Korean Foot and Ankle Society
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    • v.6 no.1
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    • pp.7-14
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    • 2002
  • Purpose: We investigate the characteristic morphologic features and suggest proper treatment of postaxial polydactyly of the foot Materials and Methods: We analysed 37 cases of postaxial polydactyly. Mean post operative follow up period was 2 years 10 months. We analysed them according to morphological, radiological and operative findings. Patients were classified into extra 5th toe polydactyly and extra 6th toe polydactyly based on the abnormal extradigit, and subdivided into joint origin type, bone origin type and floating type based on duplication pattern. Results: 23 cases were extra 5th toe polydactyly and 14 cases were extra 6th toe polydactyly. Most common types were metatarsophalangeal joint origin type of extra 6th toe polydactyly. Compared with extra 5th toe polydactyly, extra 6th toe polydactyly originated from more proximal part and had not syndactylism. Conclusion: As the duplication level was more distal, degree of syndactylism and nail union was more severe. In case of syndactyly between 5th and 6th toe, abnormal extradigit was 5th toe.

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TISSUE-ENGINEERED RECONSTITUTION OF ORAL MUCOSA USING POLYDIOXANONE MESH (Polydioxanone mesh를 이용한 구강점막의 조직 공학적 재건)

  • Moon, Seon-Jae;Joo, So-Yeon;Kim, Jin;Kim, Hak-Yong;Park, Jung-Keug;Cha, In-Ho
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.29 no.4
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    • pp.249-256
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    • 2003
  • The lack of sufficient oral mucosa available for intra-oral reconstruction has been dealt with by the use of skin or oral mucosa grafts harvested from donor sites but grafts requires more than one surgical procedures and could cause donor site morbidity. Many investigators have attempted to increase available soft tissue by tissue engineered skin or oral mucosa replacements for clinical applications. But, reconstructed mucosa by several methods have low physical properties such as rolling and contraction. The aims of this study were to develope an in vitro experimental model that maintains an epithelial-mesenchymal interaction by organotypic raft culture, and to characterize biologic properties of three-dimensionally cultured oral mucosa embedded with Polydioxanone mesh by histological and immunohistochemical analysis. The results were as follows; 1. Oral mucosa reconstructed by three-dimensional organotypic culture revealed similar morphologic characteristics to equvalent normal oral mucosa in the point that they show stratification and differentiation. 2. The expression of cytokeratin 10/13 and involucrin in the cultured tissue showed the same pattern with normal oral mucosa suggesting that organotypic co-culture condition is able to induce cellular differentiation. 3. After insertion of polydioxanone mesh, increased tensile strength were observed. These results suggest that three-dimensional organotypic co-culture of the oral mucosa cell lines with the dermal equvalent consisting type I collagen and fibroblasts reproduce the morphologic and immunohistochemical characteristics similar to those in vivo condition. And increased physical properties by use of polydioxanone mesh will helpful for clinical applications.

Morphologic and Genetic Identification of Taenia Tapeworms in Tanzania and DNA Genotyping of Taenia solium

  • Eom, Kee-Seon S.;Chai, Jong-Yil;Yong, Tai-Soon;Min, Duk-Young;Rim, Han-Jong;Kihamia, Charles;Jeon, Hyeong-Kyu
    • Parasites, Hosts and Diseases
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    • v.49 no.4
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    • pp.399-403
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    • 2011
  • Species identification of Taenia tapeworms was performed using morphologic observations and multiplex PCR and DNA sequencing of the mitochondrial cox1 gene. In 2008 and 2009, a total of 1,057 fecal samples were collected from residents of Kongwa district of Dodoma region, Tanzania, and examined microscopically for helminth eggs and proglottids. Of these, 4 Taenia egg positive cases were identified, and the eggs were subjected to DNA analysis. Several proglottids of Taenia solium were recovered from 1 of the 4 cases. This established that the species were T. solium (n=1) and T. saginata (n=3). One further T. solium specimen was found among 128 fecal samples collected from Mbulu district in Arusha, and this had an intact strobila with the scolex. Phylegenetic analysis of the mtDNA cox1 gene sequences of these 5 isolates showed that T. saginata was basal to the T. solium clade. The mitochondrial cox1 gene sequences of 3 of these Tanzanian isolates showed 99% similarity to T. saginata, and the other 2 isolates showed 100% similarity to T. solium. The present study has shown that Taenia tapeworms are endemic in Kongwa district of Tanzania, as well as in a Previously identified Mbulu district. Both T. solium isolates were found to have an "African/Latin American" genotype (cox1).

Relationship between morphological characteristics and hand emotional quotient of hands (손의 형태학적 특성과 손감성지수와의 상관관계)

  • Jeong, Eun-Young;Ryu, Hee-Wook
    • Science of Emotion and Sensibility
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    • v.13 no.4
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    • pp.769-776
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    • 2010
  • The relationship between morphological characteristics and sensibility of hands for beautiful hands were investigated for college woman in early twenties. Hand Emotional Quotient (HEQ) which is classified as 10 grades was newly suggested as one of the sensibility evaluation methods for the beautiful hands and was applied to assess the qualitative and quantitative relationships between morphological characteristics and HEQ. The factors influenced on the HEQ were in order as width-length ratio of hands, finger length-hand length and finger width-hand length ratios. Otherwise the influences of hand length-nail length and finger length-nail length ratios on HEQ were insignificant. The longer length of hand, finger, and nail and the narrower width of hand and finger, the higher HEQ hands get. In conclusion, it is found that all morphologic characteristics of hands influenced on the sensitivity synthetically. The data constructed on the hand's sensibility is very useful for various beauty products and service areas related to hands.

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Mapping of Inundation Vulnerability Using Geomorphic Characteristics of Flood-damaged Farmlands - A Case Study of Jinju City - (침수피해 정보를 이용한 농경지의 지형학적 침수취약지도 작성 - 진주시를 사례로 -)

  • Kim, Soo-Jin;Suh, Kyo;Kim, Sang-Min;Lee, Kyung-Do;Jang, Min-Won
    • Journal of Korean Society of Rural Planning
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    • v.19 no.3
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    • pp.51-59
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    • 2013
  • The objective of this study was to make a map of farmland vulnerability to flood inundation based on morphologic characteristics from the flood-damaged areas. Vulnerability mapping based on the records of flood damages has been conducted in four successive steps; data preparation and preprocessing, identification of morphologic criteria, calculation of inundation vulnerability index using a fuzzy membership function, and evaluation of inundation vulnerability. At the first step, three primary digital data at 30-m resolution were produced as follows: digital elevation model, hill slopes map, and distance from water body map. Secondly zonal statistics were conducted from such three raster data to identify geomorphic features in common. Thirdly inundation vulnerability index was defined as the value of 0 to 1 by applying a fuzzy linear membership function to the accumulation of raster data reclassified as 1 for cells satisfying each geomorphic condition. Lastly inundation vulnerability was suggested to be divided into five stages by 0.25 interval i.e. extremely vulnerable, highly vulnerable, normally vulnerable, less vulnerable, and resilient. For a case study of the Jinju, farmlands of $138.6km^2$, about 18% of the whole area of Jinju, were classified as vulnerable to inundation, and about $6.6km^2$ of farmlands with elevation of below 19 m at sea water level, slope of below 3.5 degrees, and within 115 m distance from water body were exposed to extremely vulnerable to inundation. Comparatively Geumsan-myeon and Sabong-myeon were revealed as the most vulnerable to farmland inundation in the Jinju.

Ultrasonographic Features of Triple-Negative Breast Cancer: a Comparison with Other Breast Cancer Subtypes

  • Yang, Qi;Liu, Hong-Yan;Liu, Dan;Song, Yan-Qiu
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.8
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    • pp.3229-3232
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    • 2015
  • Background: Triple-negative breast cancer (TNBC) is known to be associated with aggressive biologic features and a poor clinical outcome. Therefore, early detection of TNBC without missed diagnosis is a requirement to improve prognosis. Preoperative ultrasound features of TNBC may potentially assist in early diagnosis as characteristics of disease. Purpose: To retrospectively evaluate the sonographic features of TNBC compared to ER (+) cancers which include HER(-) and HER2 (+), and HER2 (+) cancers which are ER (-). Materials and Methods: From June 2012 through June 2014, sonographic features of 321 surgically confirmed ER (+) cancers (n=214), HER2 (+) cancers (n=66), and TNBC (n=41) were retrospectively reviewed by two ultrasound specialists in consensus. The preoperative ultrasound and clinicopathological features were compared between the three subtypes. In addition, all cases were analyzed using morphologic criteria of the ACR BI-RADS lexicon. Results: Ultrasonographically, TNBC presented as microlobulated nodules without microcalcification (p=0.034). A lower incidence of ductal carcinoma in situ (p<0.001), invasive tumor size that is>2 cm (p=0.011) and BI-RADS category 4 (p<0.001) were significantly associated with TNBC. With regard to morphologic features of 41 TNBC cases, ultrasonographically were most likely to be masses with irregular (70.7%) microlobulated shape (48.8%), be circumscribed (17.1%) or have indistinct margins (17.1%) and parallel orientation (68.9%). Especially TNBC microlobulated mass margins were more more frequent than with ER (+) (2.0%) and HER2 (+) (4.8%) cancers. Conclusions: TNBC have specific characteristic in sonograms. Ultrasonography may be useful to avoid missed diagnosis and false-negative cases of TNBC.