• Title/Summary/Keyword: Mood change

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Imunohistochemical study on the inhibition of cell mediated immunity in spleen of mouse by chronic alcohol administration : Based on the change of T lymphocytes, IL-2 receptors, and NK cells (장기간 알콜투여가 생쥐 비장의 세포성 면역 저해에 미치는 면역조직화학적 연구 : T 림프구, IL-2 수용기 및 NK세포의 변화를 중심으로)

  • Kim, Jin Taek;Park, In Sick;Ahn, Sang Hyun
    • The Journal of Dong Guk Oriental Medicine
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    • v.5
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    • pp.197-207
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    • 1996
  • As a mood-altering drug, long-term alcohol consumption have significant harmful effects on the human body and people's mental functioning. This study observed that the suppression of cell mediated immunity induced in spleen of ICR mouse by long-term alcohol administration. After 8% alcohol voluntary administered for 120 days, the splenic tissue irnmunohistochemically stained by following ABC method that used monoclonal antibody including L3T4(CD4), Ly-2(CD8), IL-2 receptor(CD25R) and NK-1.1(CD56) after embedding with paraffin. The results were as follows. 1. The size of marginal zone in splenic white pulp was diminished and the number of macrophage in marginal zone was decreased in test group than control group. 2. After alcohol administration, the number of Helper T lymphocyte, cytotoxic T lymphocyte, and IL-2 receptor were decreased in periarterial lymphatic sheaths of white pulp and penicilla artery of red pulp and the degree of CD4, CD8, and CD25R positive reaction were soften. 3. In test group, the number of NK cell were decreased. These results indicated that the secretion of lymphokine as IL-2 was inhibited by long-term alcohol administration and subsequently prevent to activate and proliferate splenic T lymphocytes and NK cells as cell mediated immunity component.

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A Qualitative Study on the Psychological Meanings of Wearing Female High-Heeled Shoes (하이힐 착용 심리에 대한 질적 연구)

  • Cho, Sun-Myoung;Kim, Hee-Sun;Koh, Ae-Ran
    • Journal of the Korean Society of Clothing and Textiles
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    • v.33 no.9
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    • pp.1361-1373
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    • 2009
  • This study analyzed female motives and psychological experiences related with high-heeled shoes. Data was collected through in-depth interviews with seven females having more than forty pairs of high-heeled shoes. Exploratory data are classified into physical aspects and mental aspects, and the meaning of wearing high-heeled shoes were derived and discussed. First, with high-heeled shoes, the participants tried to make an ideal physical appearance, 1) to make an aesthetic illusion of a longer, more slender body 2) to make a more glamorous bodyline and toned legs. Second, the psychological experiences were as follows: 1) Wearing high-heeled shoes, they felt self-confidence in appearance and had feelings of satisfaction, fulfillment, and superiority. 2) High-heeled shoes gave wearers an increased sexual appearance in addition to a feminine attitude and independent mind. Accordingly, wearers thought they could make males compliant with a better sexual look in private and public life. 3) Through buying or putting on high-heeled shoes, women could change their mood, have mental stability, and channel sexual desires. 4) Some women made the secret self with the collected high-heeled shoes for sexual fantasies. 5) They thought that painful bodies or feet were not cumbersome. In addition, some wearers thought high-heeled shoes were a natural extension of their bodies.

Effects of Vagus Nerve Stimulation on Adults and Children with Refractory Epilepsy (소아와 성인의 난치성 간질 환자에서 미주신경 자극술의 효과)

  • Kim, Cheon-Sik;Ro, Yeong-Joo;Choi, Sang-Yong;Kim, Dae-Sik
    • Korean Journal of Clinical Laboratory Science
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    • v.38 no.2
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    • pp.141-146
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    • 2006
  • Vagal nerve stimulation (VNS) has been proposed as a possible way to improve the control of refractory epilepsy. We report the effects following VNS treatment in patients with refractory epilepsy. Seventeen patients with a mean age of 12.8 years, ranging from 5 to 29 years, underwent the implantation of vagal nerve stimulation (Cyberonics, Houston, TX). We reviewed the clinical findings before and after VNS in seizure frequency, number of antiepileptic drugs (AED), and quality of life (QOL). All of the patients had intractable seizures, eleven of the patients had additional medical complications, three had hippocampus atrophy, one had encephalomalacia, five had encephalitis, one had pachygyria, and one had schizencephaly. Thirteen patients had symptomatic partial epilepsies, three patients had Lennox-Gastaut syndrome and one had cryptogenic partial epilepsy. The mean follow up duration was 35 months. The mean reduction of seizure frequency compared with baseline before VNS was 26.1% after 3 months (p<0.005), 41.9% after 6 months (p<0.001), 46.9% after 1 year (p<0.001), and 53% at the latest follow-up (p<0.001). Twelve patients showed an improvement of QOL such as mood, language, alertness, expression, and motor function. The most common side effects were transient hoarseness or voice change or cough, which was detected in six patients (35%) and wound infection in one patient (5%). This study has shown a good anti-seizure effect of VNS, decrease in seizure frequency and improvements in QOL. We concluded that VNS is a beneficial therapy in refractory epilepsy with a non-resectable epileptic focus. Further studies should be focused on the prediction of unresponsiveness and the adjustment of VNS parameters for maximum efficacy in patients with various medical histories.

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Treatment Response and Symptomatic Changes after Eye Movement Desensitization and Reprocessing in Psychiatric Disorders Other than Posttraumatic Stress Disorder (외상후 스트레스 장애 이외의 정신 장애에 대한 EMDR 전후의 치료 반응 및 증상 변화)

  • Lee, Hae-Won;Kim, Dae-Ho;Bae, Hwal-Lip;Choi, Joon-Ho;Oh, Dong-Hoon;Park, Yong-Chon
    • Anxiety and mood
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    • v.4 no.1
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    • pp.55-61
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    • 2008
  • Objective : Eye movement desensitization and reprocessing (EMDR) has been established as an effective treatment for patients with posttraumatic stress disorder (PTSD). However, the literature is unclear as to whether EMDR is effective in the treatment of other psychiatric disorders. The purpose of this study was to evaluate the potential use of EMDR in the treatment of psychiatric disorders other than PTSD by using a clinician's impression of patient response and a subjective symptom evaluation. Methods : Seventeen diagnostically heterogenous patients without PTSD underwent an average of 4.3 sessions of EMDR. Symptom severity was assessed by the Clinical Global Impression-Change Scale (CGIC), Beck Depression Inventory (BDI), State-Trait Anxiety Inventory (STAI), and Symptom Checklist-90- Revised (SCL-90-R) before and after EMDR. Those whose CGI-C scores were 'very much improved' and 'much improved' after EMDR were classified as 'responders.' The patients' before and after treatment scores of symptom severity and group differences were compared. Results : Twelve of the 17 participants (12/17, 71%) were classified as 'responders.' The patients' scores on all of the scales, with the exception of the trait anxiety scale and obsession-compulsion scale of the SCL- 90-R, significantly decreased after treatment. There was no difference in sociodemographic and clinical variables between the responders and non-responders. Conclusion : The results of our study suggest that EMDR can be a promising candidate for the treatment of patients with psychiatric disorders other than PTSD, and thus further controlled studies are needed to determine whether EMDR can be applied to various psychiatric populations.

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The Effects of Anxiety and Depression on Treatment Outcome of Social Skills Training in Adolescents with Autism Spectrum Disorder (청소년 자폐스펙트럼장애에서 사회기술훈련의 효과에 미치는 우울, 불안 증상의 영향)

  • Hong, Jung Kyung;Noh, Dong-Hyun;Oh, Miae;Kim, Ju-Hyun;Bong, Guiyoung;Yoo, Hee Jeong
    • Anxiety and mood
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    • v.14 no.2
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    • pp.99-105
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    • 2018
  • Objective : The purpose of this study was to investigate effects of depression and anxiety on treatment response of social skills training in adolescents with autism spectrum disorders (ASD). Methods : A total of 107 teenagers that participated in the Program for the Education and Enrichment of Relational Skills (PEERS$^{(R)}$) between 2011 and 2015 were analyzed using linear regression. Outcome measures used were the Korean version of Social Responsiveness Scale (SRS), the Test of Adolescent Social Skills Knowledge-Revised (TASSK-R), and the Korean version of Autism Diagnostic Observation Schedule (K-ADOS). Depression and anxiety were assessed by the Korean version of Child Depression Inventory (CDI), the Korean version of State and Trait Anxiety Inventory for Children (STAIC), and the Korean version of Child Behavior Checklist (K-CBCL). Results : As a result, depressive symptoms measured by CDI (p<0.05) and anxiety symptoms measured by STAIC (p<0.05) had significant influence on score change of social interaction domain of ADOS. It remained significant even after the baseline score was adjusted as covariates (p<0.05). Conclusion : We observed that pre-treatment anxiety and depressive symptoms of teenagers had significant effects on the treatment outcome of PEERS$^{(R)}$, especially in terms of face-to-face social interaction.

Analyzing Correlations between Movie Characters Based on Deep Learning

  • Jin, Kyo Jun;Kim, Jong Wook
    • Journal of the Korea Society of Computer and Information
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    • v.26 no.10
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    • pp.9-17
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    • 2021
  • Humans are social animals that have gained information or social interaction through dialogue. In conversation, the mood of the word can change depending on the sensibility of one person to another. Relationships between characters in films are essential for understanding stories and lines between characters, but methods to extract this information from films have not been investigated. Therefore, we need a model that automatically analyzes the relationship aspects in the movie. In this paper, we propose a method to analyze the relationship between characters in the movie by utilizing deep learning techniques to measure the emotion of each character pair. The proposed method first extracts main characters from the movie script and finds the dialogue between the main characters. Then, to analyze the relationship between the main characters, it performs a sentiment analysis, weights them according to the positions of the metabolites in the entire time intervals and gathers their scores. Experimental results with real data sets demonstrate that the proposed scheme is able to effectively measure the emotional relationship between the main characters.

The Effect of Parenting Stress and Depression and Fatigue on Quality of life in Early Postpartum Mothers (산욕기 산모의 양육스트레스, 산후우울, 피로가 삶의 질에 미치는 영향)

  • Kim, Jeong-Suk
    • Journal of Convergence for Information Technology
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    • v.8 no.6
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    • pp.1-7
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    • 2018
  • The study was investigate the effect of quality of life of mothers in the postpartum period. This study was a descriptive research study of 113 women who lived in D metropolitan area within 6-8 weeks after birth, Data were analyzed using SPSS 21.0 program ANOVA, t-test, Pearson's correlation analysis and multiple random analysis. Data collection was from August 2018 to September 2018. The results were as follows. The most influential factors on quality of life were parenting stress(${\beta}=-.646$, p =.000), fatigue(${\beta}=-.329$, p =.009). It is necessary to develop a nursing intervention program related to physical and mental health because maternal quality of life leads to lower quality of life when feeling emotional mood change such as emptiness and depression.

A Study on Wellbeing Support System for the Elderly using AI (고령자를 위한 AI 기반의 Wellbeing 지원 시스템의 연구)

  • Cho, Myeon-Gyun
    • Journal of Convergence for Information Technology
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    • v.11 no.2
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    • pp.16-24
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    • 2021
  • This paper introduces a smart aging service that helps the elderly lead a happy old age by actively utilizing IoT and AI technologies for the elderly who are increasing rapidly as they enter the aging society. In particular, we propose a future-oriented, age-friendly well-being support system that breaks away from the existing welfare concept to solve the aging problem but leads to a paradigm shift toward building a vibrant aging society by protecting from emergency and satisfying emotions. By introducing IoT and AI, it judges the life situation and emotional state from the living information of the elderly can respond to emergencies and suggest meetings as a change of mood and give an emotional comfort. Since the proposed system uses artificial intelligence techniques to determine the degree of depression when inputting information such as pulse-rate, dangerous word usage, and external communication, I think it showed the feasibility of the new concept of wellbeing support system that is totally different from conventional wellbeing concept of health-care.

Impact of coronavirus disease 2019 on patients with chronic pain: multicenter study in Korea

  • John, Hyunji;Lim, Yun Hee;Hong, Sung Jun;Jeong, Jae Hun;Choi, Hey Ran;Park, Sun Kyung;Kim, Jung Eun;Kim, Byung-soo;Kim, Jae Hun
    • The Korean Journal of Pain
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    • v.35 no.2
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    • pp.209-223
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    • 2022
  • Background: The coronavirus disease 2019 (COVID-19) pandemic has caused significant changes. This study aimed to investigate the impact of COVID-19 on patients with chronic pain. Methods: Patients with chronic pain from 23 university hospitals in South Korea participated in this study. The anonymous survey questionnaire consisted of 25 questions regarding the following: demographic data, diagnosis, hospital visit frequency, exercise duration, time outside, sleep duration, weight change, nervousness and anxiety, depression, interest or pleasure, fatigue, daily life difficulties, and self-harm thoughts. Depression severity was evaluated using the Patient Health Questionnaire-9 (PHQ-9). Logistic regression analysis was used to investigate the relationship between increased pain and patient factors. Results: A total of 914 patients completed the survey, 35.9% of whom had decreased their number of visits to the hospital, mostly due to COVID-19. The pain level of 200 patients has worsened since the COVID-19 outbreak, which was more prominent in complex regional pain syndrome (CRPS). Noticeable post-COVID-19 changes such as exercise duration, time spent outside, sleep patterns, mood, and weight affected patients with chronic pain. Depression severity was more significant in patients with CRPS. The total PHQ-9 average score of patients with CRPS was 15.5, corresponding to major depressive orders. The patients' decreased exercise duration, decreased sleep duration, and increased depression were significantly associated with increased pain. Conclusions: COVID-19 has caused several changes in patients with chronic pain. During the pandemic, decreased exercise and sleep duration and increased depression were associated with patients' increasing pain.

Service Pursuit Benefits and Revisit Intent Based on Nail Shop Customers' Self-Confidence and Self-Respect (네일숍 고객의 자신감과 자아존중감에 따른 서비스 추구 혜택 및 재방문 의도에 관한 연구)

  • Kim, Minhee;Park, Hanhim
    • Journal of Fashion Business
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    • v.26 no.1
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    • pp.92-104
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    • 2022
  • The nail service field, which has emerged as a new trend in the beauty industry, is showing rapid growth compared to other beauty fields. As nail beauty services become more common and popular, studies on related fields are also actively progressing, but most of the research has been focused on changes on self-esteem. In addition, most of the preceding studies are centered on female customers, thus, there is little data on male customers that are increasing recently. This research aims to provide customized marketing data to the nail beauty service industry by analyzing the psychological characteristics of the customers and their motives by selecting self-esteem and confidence as factors. First, the customers' confidence and self-esteem were classified into a group with high and low confidence and self-esteem, and as a result of analyzing the difference in service pursuit benefits and revisit intentions, there were significant differences in mood change, professionalism, health hygiene, aesthetics, and revisit. Second, as a result of analyzing the effect of the service pursuit benefits of male and female customers on the revisit intention, it was found that only health and hygiene had a significant effect on the revisit intention. Female customers also had a significant influence on their revisit intention, which is judged to have a significant effect on male customers' revisit intention because most of the main management is cuticle cleaning, callus management, and problematic nails.