• 대한약학회:학술대회논문집
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• 대한약학회 2000년도 춘계총회 및 학술대회
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• pp.129.2-129.2
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• 2000

• 대한약학회:학술대회논문집
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• 대한약학회 2001년도 Proceedings of the Pharmaceutical Society of Korea
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• pp.149.1-149.1
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• 2001

• 한국콘텐츠학회:학술대회논문집
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• 한국콘텐츠학회 2009년도 춘계 종합학술대회 논문집
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• pp.235-238
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• 2009

캐릭터는 문화적 콘텐츠이며 이를 시각화하여 자국의 문화를 보여주고 그 문화를 전달하는 매개체적인 잠재력이 점점 커지는 영역이다. 캐릭터들을 살펴보면 고전에 나타난 인물들로 제작된 캐릭터를 많이 찾아 볼 수 있다. 고전은 하나의 국가 혹은 민족의 문화에서 그 원형을 찾아볼 수 있다. 본고에서는 고전신화소설 [서유기]를 모델로 하여 제작된 만화 한국의 [미스터 손(날아라! 슈퍼보드)], 중국의 [大鬧天宮 제천대성 손오공 (제천대성 손오공)], 일본의 [ぼくの孫悟空(나의 손오공)]에 등장하는 손오공캐릭터를 중심으로 한국 중국 일본 캐릭터디자인을 비교 분석하였다. 분석한 결과 한국은 퓨전 적이며 글로벌 적인 경향을 나타내고 있고, 반면 중국은 전통문화에 대한 부각에 치중하고 있으며, 일본은 디테일한 부분에 자신의 전통적인 문화요소를 부여하여 보다 대중적인 수용성을 추구하려는 경향을 보이고 있으며 이는 캐릭터디자인이 각 나라별로 문화와 밀접한 관계가 있음을 시사하고 있다.

• Molecular & Cellular Toxicology
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• 제4권4호
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• pp.323-330
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• 2008

Surrogate tissue analysis incorporating -omics technologies has emerged as a potential alternative method for evaluating toxic effect of the tissues which are not accessible for sampling. Among the recent applications, blood including whole blood, peripheral blood lymphocytes and peripheral blood mononuclear cells (PBMCs) was suggested as a suitable surrogate tissue in determining toxicant exposure and effect at the pre- or early clinical stage. In this application, we investigated transcriptomic profiles in astemizole treated Cynomolgus monkey's PBMCs. PBMCs were isolated from 4-6 years old male monkeys at 24 hr after administration45 Helvetica Light (10 mg/kg, 30 mg/kg). Gene expression profiles of astemizole treated monkey's PBMCs were determined using Affymetrix $GeneChip^{(R)}$ Human Genome U133 plus 2.0 arrays. The expression levels of 724 probe sets were significantly altered in PBMCs at 10 or 30 mg/kg after astemizole administration following determination of paired t-test using statistical criteria of ${\geq}$$1.5-fold changes at P<0.05. Gene expression patterns in PBMCs showed a considerable difference between astemizole 10 and 30 mg/kg administration groups in spite of an administration of the same chemical. However, close examination using Ingenuity Pathway Analysis (IPA) software revealed that several gene sets related to cardiotoxicity were deregulated at astemizole 10 and 30 mg/kg administration groups. The deregulation of cardiac hypertrophy related genes such as TXN, GNAQ, and MAP3K5 was observed at 10 mg/kg group. In astemizole 30 mg/kg group, genes involved in cardiotoxicity including cardiac necrosis/cell death, dilation, fibrosis, and hypertrophy were also identified. These results suggest that toxicogenomic approach using PBMCs as surrogate tissues will contribute to assess toxicant exposures and identify biomarkers at the pre-clinical stage.

• 동의생리병리학회지
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• 제26권1호
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• pp.1-9
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• 2012

Five mimic-animal boxing(五禽戱, FAB) is physical fitness exercises conducted by imitating the motions of tiger, deer, bear, monkey, and bird, devised by the famous doctor Hwa-Ta(華陀) in the Three Kingdoms of China. FAB is one of bionic-physical and breathing exercises(傍生導引) by combined automassage as a practice for health care. Although FAB have effects of health control and medical treatment, but interrelationship of five animals(五禽) of FAB and five viscera(五臟) of five elements(五行) is complicated. So, the present was designed to investigate the progress of FAB, movement-feature of FAB, and the interrelationship of five animals and five viscera. further I will develop value by sports-treatment medicine in oriental medicine. The results were as follows ; FAB is physical exercises of dynamic exercises and new-dynamic exercises. Feature of China-FAB have each movement by imitating the motions of each animals, movements of Formosa-FAB were mixed. In philosophical viewpoint, Five animals (tiger, deer, bear, monkey, bird) were attached to metal, wood, water, earth, fire of five elements, and lung, liver, kidney, spleen, heart of five viscera. In viewpoint of breathing exercises, Five animals (tiger, deer, bear, monkey, bird) were attached to water, wood, earth, fire, metal of five elements, and kidney, liver, spleen, heart, lung of five viscera. Although FAB have effects of health control and medical treatment, FAB have indication and contraindication. Therefore, I think that mechanism of treatment should reason with Oriental medicine doctor in FAB.

• 대한수의사회지
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• 제20권12호
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• pp.762-764
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• 1984

Cytoplasmic inclusion bodies are observed by light microscopy in the epithelial cells of three livers and one corpus luteum from among the six rhesus monkeys available for this study. The various-sized inclusions are homogeneous, acidophilic, round to ova

• 한국환경독성학회:학술대회논문집
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• 한국환경독성학회 2000년도 추계심포지움 및 학술발표회:바이오모니터링 기법을 이용한 환경위해성 평가
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• pp.79-79
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• 2000

• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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• pp.167.1-167.1
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• 2002

• Journal of Life Science
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• 제10권1호
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• pp.37-39
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• 2000

Testis-specific protein Y(TSPY) is thought to play an important role during spermatogenesis in primates. The Arg and Lys-rich region of TSPY was implicated as a potential DNA binding site in the human and Japanese monkey. In the study, we investigated this further through looking at the putative amino acid sequences of Arg and Lys-rich region of TSPY gene from seven species of gibbons, five species of Old World monkeys and five species of New World monkeys. A comparison with those of the human and Japanese monkey revealed that the Arg and Lys-rich motif was hightly conserved in various primates. This finding suggests that a possible role for the Arg and Lys-rich motif in primate TSPY is DNA recognition. The functional implications for TSPY are discussed in the light of this and previous findings.

• Animal cells and systems
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• 제7권4호
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• pp.317-325
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• 2003

Corticostriatal connections of auditory areas within the rostral and caudal portions of the superior temporal gyrus (STG) and in the supratemporal plane(STP) of pigtail macaque (Macacca nemestrina) were studied with particular emphasis on specific projections to the ventral striatum. Retrograde tracers were Injected into five different regions of the ventral striatum such as the ventromedial caudate nucleus, ventral shell, central shell, dorsal core of the nucleus accumbens (NA), and ventrolateral putamen to Identify the cells of origin. There were only few projections from the auditory areas in the STP to the ventral striatum. However, the association (or belt) areas of the STG collectively had widespread corticostriatal projections characterized by differential topographic distributions. The rostral parts of the STG strongly projected to the ventromedial caudate nucleus. The midportion of the STG also projected to the same ventral striatal regions, but the connections were relatively less extensive. Interestingly, the caudal portion of the STG had no connection to all subregions of the ventral striatum. These differential patterns of corticostriatal connectivity suggest that the ventromedial caudate nucleus would be a major auditory convergence area and mainly involved in sound recognition rather than spatial localization of sound sources.