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A partially hydrolyzed whey formula provides adequate nutrition in high-risk infants for allergy

  • Yang, Jiyeon;Yang, Song I;Jeong, Kyunguk;Kim, Kyung Won;Kim, Yoon Hee;Min, Taek Ki;Pyun, Bok Yang;Lee, Jeongmin;Jung, Ji A;Kim, Jeong Hee;Lee, Sooyoung
    • Nutrition Research and Practice
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    • v.16 no.3
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    • pp.344-353
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    • 2022
  • BACKGROUND/OBJECTIVES: Hydrolyzed formula is often fed to infants with gastrointestinal or immune issues, such as malabsorption or cow's milk allergy, because enzymatic treatment has rendered it more digestible and less allergenic than standard cow's milk formula (SF). Partially hydrolyzed formula (PHF) should be considered for those infants who are intolerant to extensively hydrolyzed formula. However, there are concerns about the nutritional insufficiencies of PHF. We aimed to evaluate the effects of PHF on the growth and health indicators in infants who were at high-risk of allergic disease and potential candidates for consuming PHF. SUBJECTS/METHODS: A total of 83 infants aged 0-2 mon with a family history of allergies were assigned to consume either PHF or SF until 24 weeks of age. Anthropometric measures were obtained at baseline, 12 weeks, and 24 weeks; blood samples were drawn and evaluated at the end of the study. RESULTS: No significant differences were observed in weight, height, and weight-for-height at any time point in each sex between the PHF and SF groups. At 24 weeks of age, the weight-for-age and height-for-age z-scores of the SF group were higher than those of the PHF group, but there was no significant difference in the weight-for-height z-score. There were no significant differences in levels of white blood cells, hemoglobin, ferritin, protein, albumin, aspartate aminotransferase, alanine aminotransferase, eosinophil cationic protein, and immunoglobulin E. CONCLUSIONS: In this study, there were no differences in growth and blood panels between the infants consuming PHF or SF. Therefore, infants who are unable to tolerate SF can be fed PHF without nutritional concerns about growth.

2020 Dietary Reference Intakes for Koreans: zinc (2020 한국인 영양소 섭취기준: 아연)

  • Lee, Mi-Kyung;Kim, Eun-Mee;Kwun, In-Sook
    • Journal of Nutrition and Health
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    • v.55 no.4
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    • pp.441-449
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    • 2022
  • This review is focused on analyzing the limits and shortage of zinc (Zn) for the 2020 Dietary Reference Intakes for Koreans (KDRIs), and provides suggestions for the future establishment of the 2025 KDRIs for Zn. The 2020 KDRIs for Zn have been established to estimate the adequate requirement (EAR), recommended nutrient intakes (RNI), adequate intake (for only 0-5 mon) and tolerable upper intake level (UL). EAR was estimated in 2-stages: the first stage was to construct of the frame of analysis for Zn requirement and the second stage involved a factorial approach by considering the various factors which affect Zn requirement, such as intestinal and urine Zn loss, Zn requirement for growth and development, and Zn absorption rate. For a more precise and accurate establishment of the Zn requirement, we suggest for the following to be considered: 1) considering that Zn is present in minuscule amounts as a trace element in our body, the present values for Zn EAR (as 6-9 mg/d) should be expressed as a decimal point for more accurate DRIs; 2) the frame of analysis for Zn requirement has to be more specifically and should includes the factors which affect Zn requirement; 3) both, the factorial approach and extrapolation method need to be well reviewed and thoroughly understood for establishing precise Zn requirement; 4) currently, human clinical study and balance study (Zn intake, excretion and absorption rate) are limited and more human Zn subject studies are required. All these suggestions are provided to better establish the Zn requirement in the 2025 KDRIs.

Breeding and characterization of 'Creamy', a new interspecific hybrid between Pleurotus ferulae and P. tuoliensis (아위느타리와 백령느타리의 종간교잡 품종 '크리미'의 육성 및 특성)

  • Oh, Min-Ji;Shin, Pyung-Gyun;Lim, Ji-Hoon;Oh, Youn-Lee;Jang, Kab-Yeul;Kong, Won-Sik
    • Journal of Mushroom
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    • v.17 no.4
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    • pp.224-229
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    • 2019
  • The two most common mushroom species grown in Korea are pearl oyster mushroom (Pleurotus ostreatus) and king oyster mushroom (P. eryngii). In recent years, the production of king oyster mushroom greatly increased due to the automation of the cultivation facilities, and it became a major export mushroom owing to its excellent shelf life. However, the increase in the production of king oyster mushroom led to a decline in its market price; thus, necessitating the development of new mushroom species that could replace king oyster mushroom, to diversify the mushroom market for the benefit of both, the producers and the consumers. The Mushroom division at the National Institute of Horticultural & Herbal Science (NIHHS) reported the development of a new interspecific hybrid between P. ferulae and P. tuoliensis, referred to as 'Creamy.' Two parental strains KMCC00430 (Bisan2ho, P. ferulae) and KMCC00461 (P. tuoliensis) were selected based on the results of genetic resource analysis, and their monokaryons were collected. About 1,000 Mon-Mon crosses were performed and 73 of them were selected. Following repeated cultivation tests and strain analyses, we selected strain 7773, which had a bright creamy pileus and a thick straight stipe, and named it 'Creamy.' Optimum temperature for mycelial growth of Creamy was 25-30℃, and that for fruiting body growth was 16℃. The pileus, which had a brighter creamy color, was small in size with a diameter of 61.2 mm. Although it was cultivated in suboptimal conditions, such as low temperature and high CO2 concentration, Creamy was characterized by its straight and smooth stipe. Field production tests and further analyses indicated that the yield of Creamy was 5% higher than that of Baekhwang. It is expected that Creamy, the new interspecific hybrid with a bright creamy pileus and a pleasant flavor, will help create new opportunities for mushroom farmers and diversify the mushroom market.

A Study of Age Rating Criteria for Outdoor Augmented Reality Game (실외형 증강현실 게임의 등급분류기준에 관한 연구)

  • Kang, Ju-young;Lee, Hwan-soo
    • Journal of Digital Convergence
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    • v.14 no.10
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    • pp.439-447
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    • 2016
  • Interest in Augmented Reality (AR) game $Pok{\acute{e}}mon$ GO is getting heightened. However, based on its characteristic, various direct and indirect problems are highlighted, thus increasing concerns. Although the game is not formally released domestically, there are limits in national game classification to apply on such outdoor Augmented Reality game. This paper will examine the problematic cases regarding Pokemon GO and analyze internal and external game classification system to discuss safe gaming measures for domestic users. In result of examining cases, need for adding 'physical danger' in current game classification system for user's safety was shown. As the government's game regulation is being eased, appearance of a variety of games using Augmented Reality technology in near future is predicable. Therefore it is important to prepare improvement of game classification system as a pre-safety measure, and it is expected to bring positive effect on game usage and industrial growth through safe game usage.

An Investigation into Perceptions of Potential Customers in Busan towards Well-being Apartments (웰빙 아파트에 대한 부산지역 잠재 수요자의 인식 조사)

  • Kim Ju-Hyung;Bin Ju-Yeong;Oh Seung-Moon
    • Korean Journal of Construction Engineering and Management
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    • v.5 no.6 s.22
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    • pp.154-161
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    • 2004
  • The term 'well-being' which becomes a popular trend in various industries has been introduced in the housing market as well. This trend could be understood as an emerging trend rooted to customers' preference for apartment enabling residents to live comfortably and healthy in 2000s. The housing industry has attempted to meet customers' requirements by presenting' well-being apartments' emphasizing healthy and natural-friendly aspects. For instance, suppliers in the industry has adopted master plans and unit plans to support well-being residence. In addition, they introduced less-toxic-emission materials to interior However, it has been unknown that customers in the housing market also agree to well-being functions presented by suppliers and, if then, which aspects they consider mon important In order to answer questions stated above, a research to investigate perceptions of potential customers in Busan towards well-being apartments is designed and this paper is a summarized result. Based on the real-world investigations, the important functions or concepts relevant to well-being apartments perceived by customers are defined and suppliers' approach to meet these Is presented.

Establishment of Quantitative Analysis Method for Genetically Modified Maize Using a Reference Plasmid and Novel Primers

  • Moon, Gi-Seong;Shin, Weon-Sun
    • Preventive Nutrition and Food Science
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    • v.17 no.4
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    • pp.274-279
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    • 2012
  • For the quantitative analysis of genetically modified (GM) maize in processed foods, primer sets and probes based on the 35S promoter (p35S), nopaline synthase terminator (tNOS), p35S-hsp70 intron, and zSSIIb gene encoding starch synthase II for intrinsic control were designed. Polymerase chain reaction (PCR) products (80~101 bp) were specifically amplified and the primer sets targeting the smaller regions (80 or 81 bp) were more sensitive than those targeting the larger regions (94 or 101 bp). Particularly, the primer set 35F1-R1 for p35S targeting 81 bp of sequence was even more sensitive than that targeting 101 bp of sequence by a 3-log scale. The target DNA fragments were also specifically amplified from all GM labeled food samples except for one item we tested when 35F1-R1 primer set was applied. A reference plasmid pGMmaize (3 kb) including the smaller PCR products for p35S, tNOS, p35S-hsp70 intron, and the zSSIIb gene was constructed for real-time PCR (RT-PCR). The linearity of standard curves was confirmed by using diluents ranging from $2{\times}10^1{\sim}10^5$ copies of pGMmaize and the $R^2$ values ranged from 0.999~1.000. In the RT-PCR, the detection limit using the novel primer/probe sets was 5 pg of genomic DNA from MON810 line indicating that the primer sets targeting the smaller regions (80 or 81 bp) could be used for highly sensitive detection of foreign DNA fragments from GM maize in processed foods.

A study on the implementation of digital fisheries information network using PSK31 on MH/HF radio Band (PSK31 통신방식을 활용한 MF/HF대역 무선 디지털 어업정보통신망 구현에 관한 연구)

  • Lee, Dae-Ryung;Park, Keun-Seong;Kim, Ki-Mon
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.14 no.6
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    • pp.1365-1374
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    • 2010
  • The maritime traffic is more complex these days. It is more hard for the small fishing ships to navigated in shores. The requirements for the navigate information system to protect the sea environments and support the small fishing ships are more increased. However, the Inmarsat communication system is too burden to the fishermen with the expensive terminal and call fees. We propose the wireless digital fishing information network which use the existing MF/HF SSB communications system by connecting I-PHONE, PDA, NetBook, Notebook, PC, etc with the PSK31 method and AIS(Automatic Identification System) on the MF/HF radio Band.

Transmission of Bovine $\beta-Casein/Human$ Lactoferrin Fusion Gene in Transgenic Cattle

  • Han Yong-Mahn;Koo Deog-Bon;Park Jung-Sun;Kim Young-Hun;Lee Kea-Joung;Lee Kyung-Kwang
    • Reproductive and Developmental Biology
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    • v.29 no.4
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    • pp.235-239
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    • 2005
  • This study was conducted to test whether the transgenic cattle pass the transgene to their progeny through germ cells, and whether the transgene is expressed in the mammary gland of ransgenic cows. Two male ransgenic calves were born from IVF-derived embryos injected with bovine $\beta-casein/human$ lactoferrin fusion gene and then grew up to be reproducible. Semen was collected from a transgenic bull after 18 mon of age and then frozen. Bovine oocytes matured in vitro were fertilized with spermatozoa of the transgenic bull and cultured in $50\;{\mu}L$ drops of CRlaa medium supplemented with 3 mg/mL BSA. After 48 h of culture, cleaved embryos were determined for the presence of transgenes by DNA polymerase chain reaction (PCR). Proportion of transgene positives among bovine embryos fertilized with sperm of the transgenic bull was $20.9\%$ (28/134). One of transgenic bulls did not produce transgenic sperm. Out of 34 calves produced from recipient heifers inseminated with semen of the other bull, 3 $(8.8\%)$ were transgenic animals (2 females and 1 male). Thus, one transgenic bull showed a low transmission frequency below Mendelian levels in both the IVF-derived embryos and his progeny. It was demonstrated by Southern blot that copy numbers of the transgene in the transgenic progeny enhanced about 1.8 times as compared to those of the founder bull The results demonstrate that the transgenic bull carrying human lactoferrin gene could pass his transgene to the progeny through germ cells, although he is a germ-line mosaic.

Mechanical Properties of Aminosilane-Treated Wood Flour/PVC/Nanoclay Composites (아미노실란으로 개질된 목분/PVC/나노점토 복합재의 기계적 특성)

  • Park, Sol-Mon;Kim, Dae-Su
    • Polymer(Korea)
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    • v.36 no.5
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    • pp.573-578
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    • 2012
  • In general, most physical properties of wood/polyvinyl chloride (PVC) composites are lower than those of corresponding neat PVC resin because of poor interfacial adhesion between the hydrophilic wood flour and hydrophobic PVC. Therefore, in this study, we treated wood flour with three aminosilanes to improve wood/PVC interfacial adhesion strength, and eco-friendly wood/PVC/nanoclay composites were prepared by melt blending the aminosilane-treated wood flour, a heavy metal free PVC compound, and a type of nanoclay. The effects of treating wood flour with the aminosilanes and adding the nanoclay on the mechanical properties of the composites were investigated. Mechanical properties of the composites were investigated by universal testing machine (UTM), izod impact tester, dynamic mechanical analyzer (DMA), and thermomechanical analyzer (TMA). The tensile properties of the composites with the aminosilane-treated wood flour were considerably higher than those of the composites with neat wood flour. Furthermore, a small amount of the nanoclay improved mechanical properties of the composites. The performance of the wood/PVC composites was considerably improved by using the aminosilane-treated wood flour and the nanoclay.

A Study on the Relation between Taxonomy of Nominal Expressions and OWL Ontologies (체언표현 개념분류체계와 OWL 온톨로지의 상관관계 연구)

  • Song Do-Gyu
    • Journal of the Korea Society of Computer and Information
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    • v.11 no.2 s.40
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    • pp.93-99
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    • 2006
  • Ontology is an indispensable component in intelligent and semantic processing of knowledge and information, such as in semantic web. Ontology is considered to be constructed generally on the basis of taxonomy of human concepts about the world. However. as human concepts are unstructured and obscure, ontology construction based on the taxonomy of human concepts cannot be realized systematically furthermore automatically. So, we try to do this from the relation among linguistic symbols regarded representing human concepts, in short, words. We show the similarity between taxonomy of human concepts and relation among words. And we propose a methodology to construct and generate automatically ontologies from these relations mon words and a series of algorithm to convert these relations into ontologies. This paper presents the process and concrete application of this methodology.

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