• Bulletin of the Korean Chemical Society
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• v.32 no.4
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• pp.1221-1227
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• 2011

Ethyl pyruvate (EP) is known as a scavenger of reactive oxygen species (ROS) in the body through its role in the donation of diketone groups to metals to form an EP-metal complex. In order to develop a method for the quantification of EP in biological media, a sensitive and specific, high-performance liquid chromatographyelectrospray ionization-mass spectrometry (HPLC-ESI/MS) method is used to determine the EP-alkali metal ion binding species. The analyte was separated on a ZORBOX SB-C8 ($3.5{\mu}m$, $30mm{\times}2.1mm$ I.D.) column and analyzed in selected ion monitoring (SIM) mode with a positive ESI interface using the m/z 255 $[2M + Na]^+$ ion. The method was validated over the concentration range of $0.5-60.0\;{\mu}g$/mL under 1/9 (v/v) of acetonitrile/methanol solvent system with flow rate 0.05 mL/min. The limit of quantification (LOQ) was $0.5{\mu}g$/mL.

• Proceedings of the KSME Conference
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• 2003.11a
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• pp.816-821
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• 2003

The pumping characteristics of a disk-type drag pump (DTDP) from free molecular flow region to the slip flow region are calculated by the direct simulation Monte Carlo (DSMC) method. In this study, the pumping performance is studied numerically for several channel depths. The interaction between molecules is modeled by variable hard-sphere (VHS). The no time counter method is used as a collision sampling technique. The clearance between rotor and stator is considered an effect on performance. Spiral channels are cut on both upper and lower sides of rotating disks, and stationary disks are planar. A three-dimensional DSMC method for the analysis of steady rarefied flows in a single-stage DTDP has been developed. Velocity and density fields were obtained by the DSMC simulation in the rotor. The present experimental data in the outlet pressure range of $7.5{\times}10^{-3}{\sim}4$ Torr were compared with the DSMC results in the single-stage DTDP. Comparison between the experimental data and DSMC results showed good agreement.

• Applied Chemistry for Engineering
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• v.9 no.7
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• pp.950-955
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• 1998

The objective of this study was to investigate the effect of running time, operating pressure, feed concentration and circulation rate on the permeation flux and the rejection rate in cross-flow ultrafiltration of polyethylene glycol(PEG) solution of molecular weight($M_w$) 8000 and 20000. The membranes used for this study were MWCO(Molecular Weight Cut-off) of 6 K and 20 K. The experiments were performed at the operating pressures of 7, 14 and 28 psi, the circulation rates of 1000 mL/min and 2000 mL/min, and the feed concentration of 100 mg/L and 1000 mg/L. At a constant pressure, the permeation flux and the observed rejection($R_o$) appeared to be approximately constant within the range of running time, 0~480 min. The permeation flux increased with increasing the operating pressure, and it increased with decreasing the feed concentration and decreasing Mw of PEG at a given pressure. On the other hand, $R_o$ decreased slightly with increasing the operating pressure. However, $R_o$ increased with increasing the feed concentration and increasing of $M_w$ of PEG at a given pressure. The variation in circulation rates did not cause any significant influence on the permeation flux. Increasing of circulation rate caused the increase of $R_o$, and $\alpha$ was increased substantially with the decrease of $M_w$ of PEG. The dimensionless parameter. permeability ratio($\alpha$), which was used to investigate flux-pressure behavior, was increased with the increase in circulation rate and operating presure. The value of $\alpha$ was less than 1 in all cases. The estimated intrinsic rejection(R). which was obtained from mass transfer coefficient, was decreased with the increase of operating pressure. However R increased with the increase of linear velocity of feed and $M_w$ of PEG.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2008.11a
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• pp.241-242
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• 2008

The Velocity Autocorrelation Function (VAF) of the sodium ions is calculated for a range of temperature from 250K to 1000K and converted into the linear ac-conductivity and ac-susceptibility response via Fourier transformation. A peak is found in the conductivity around $6\times10^{12}$ Hz that has some of the character of a Poley absorption. Here it is shown to be due to an harmonically coupled site vibrations of the sodium atoms, which extend only over a limited range. At frequencies below the peak the conductivity tends towards a constant i.e. dc value corresponding to a constant flow of ions through the simulation cell. At high temperatures the conductivity due to this ion transport process behaves like a metal with an insulator to metal transition occurring around a specific temperature.

• Proceedings of the KIEE Conference
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• 2008.07a
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• pp.2299-2300
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• 2008

The Velocity Autocorrelation Function (VAF) of the sodium ions is calculated for a range of temperature from 250K to 1000K and converted into the linear ac-conductivity and ac-susceptibility response via Fourier transformation. A peak is found in the conductivity around $6{\times}10^{12}$ Hz that has some of the character of a Poley absorption. Here it is shown to be due to an harmonically coupled site vibrations of the sodium atoms, which extend only over a limited range. At frequencies below the peak the conductivity tends towards a constant i.e. dc value corresponding to a constant flow of ions through the simulation cell. At high temperatures the conductivity due to this ion transport process behaves like a metal with an insulator to metal transition occurring around a specific temperature.

• The Korean Journal of Ceramics
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• v.6 no.3
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• pp.318-321
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• 2000

Most compressive strengths commonly used in the construction field are in a range of 240 to 300 kgf/$\textrm{cm}^2$ at 28 days. To get this rage of strengths, however, high-flowing concrete requires cementitious binders more than 400 to 450 kg/$\textrm{cm}^2$ for preventing segregation and sedimentation of aggregates. This amount of cementitious binder generates a large emission of excessive hydration heat, which may consequently induce harmful cracks in concrete structure. In order to reduce excessive hydration heat, thus, this paper aims at fabricating a high-flowing concrete under the condition that cement content is kept as low as 350kg/$\textrm{cm}^3$ by using viscose agents. In a parametric study, effects of cement types such as a ternary blended cement and Type V on he physical characteristics of high-flowing concrete were evaluated. In addition, the influence of viscosity was also investigated by applying two different viscose agents, one in a range of 6,000 to 10,000 cps and the others of 10,000 to 14,000 cps. In terms of chemical admixtures used in concrete mixture, the superplasticizer was Sulfonated Melamine-Formaldehyde Condensate with about 30,000 of molecular weight, and main component of viscose agent was HPMC (Hydroxy Propyl Methyl Cellulose). Slump flow was fixed at 50cm with different dosages of superplasticizer in weight.

• Proceedings of the KSME Conference
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• 2002.08a
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• pp.577-580
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• 2002

In this paper, the pumping performance of the disk-type drag pump which works in the outlet pressure range from 4 to 0.001 Torr is studied experimentally. The pumping characteristics of various drag pumps are performed. The inlet pressures are measured for various outlet pressures of the test pump. The flow-meter method is adopted to calculate the pumping speed. Compression ratios and pumping speeds for the nitrogen gas are measured. The present experimental data show the leak-limited value of the compression ratio in the molecular transition region. The rotational speed of the pump is 24,000rpm. The inlet pressures are measured for various outlet pressures of the test pump. The ultimate Pressures for zero throughput are measured for three-stage, two-stage and single-stage disk-type, respectively.

• Korean Journal of Food Science and Technology
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• v.19 no.3
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• pp.225-230
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• 1987

The foam separation of bovine serum proteins was investigated and the protein fractionation by foam separation was analyzed by PAG electrophoresis. The protein concentration for the surface excess formation of bovine serum was in the range of $20-800\;{\mu}g/ml$. At pH 5, the foamate volume was maximum, but the enrichment ratio minimum. As the temperature was elevated, the foamate volume decreased and the enrichment ratio increase. As the gas flow rate increased from 25 to 100 ml/min, the foamate volume decreased and the enrichment ratio increased. The enrichment ration became maximum when the added ionic strength of serum solution was in the range of 1-3 by the addition of different types of salts, and this was related to the reduction of surface tension of the solution. In general, BSA, ${\alpha}_1$, and ${\alpha}_2-globulins$, which have relatively small molecular weight and high hydrophobicity, moved easily to the foam, and the separation of protein fractions in the serum varied with the changes in pH, temperature, gas flow rate and ionic strength of the solution.

• Aerospace Engineering and Technology
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• v.8 no.1
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• pp.144-153
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• 2009

To study the plume effects in the rarefied region, the Direct Simulation Monte Carlo(DSMC) method is usually adopted because the plume field usually contains the entire range of flow regime from the near-continuum in the vicinity of nozzle exit through transitional state to free molecular at far field region from the nozzle. The objective of this study is to investigate the behaviors of a small monopropellant thruster plume in the rarefied region numerically using DSMC method. To deduce accurate results efficiently, the preconditioned scheme is introduced to calculate continuum flow fields inside thruster to predict nozzle exit properties used for inlet conditions of DSMC method. By combining these two methods, the rarefied flow characteristics of plume such as strong nonequilibrium near nozzle exit, large back flow region, etc, can be investigated.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.37 no.9
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• pp.906-915
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• 2009

To study the plume effects in the vacuum area, the Direct Simulation Monte Carlo(DSMC) method is usually adopted because the plume field usually contains the entire range of flow regime from the near-continuum in the vicinity of nozzle exit through transitional state to free molecular at far field region from the nozzle. The objective of this study is to investigate the behaviors of a small monopropellant thruster plume in the vacuum area numerically using DSMC method. To deduce accurate results efficiently, the preconditioned scheme is introduced to calculate continuum flow fields inside thruster to predict nozzle exit properties used for inlet conditions of DSMC method. By combining these two methods, the vacuum flow characteristics of plume such as strong nonequilibrium near nozzle exit, large back flow area, etc, can be investigated.