• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2004년도 추계학술대회 논문집
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• pp.774-777
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• 2004

A rheology casting technology has some advantages compared with conventional forming processes such as die casting, squeeze casting and hot/cold forming. The liquid segregation is important on mechanical properties of materials using rheology casting. In this study, so, molecular dynamics simulations were performed for the control of liquid segregation. Because the dynamics of fluid flow about nano-scaled materials is completely different from continuum, molecular dynamics simulations were used. The behavior of particles was far from the truth according to boundary conditions in simple flow. But various movement of particles appear at two or more molecular simulations.

• Korea-Australia Rheology Journal
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• 제14권4호
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• pp.161-174
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• 2002

A new technique for numerical calculation of viscoelastic flow based on the combination of Neural Net-works (NN) and Brownian Dynamics simulation or Stochastic Simulation Technique (SST) is presented in this paper. This method uses a "universal approximator" based on neural network methodology in combination with the kinetic theory of polymeric liquid in which the stress is computed from the molecular configuration rather than from closed form constitutive equations. Thus the new method obviates not only the need for a rheological constitutive equation to describe the fluid (as in the original Calculation Of Non-Newtonian Flows: Finite Elements St Stochastic Simulation Techniques (CONNFFESSIT) idea) but also any kind of finite element-type discretisation of the domain and its boundary for numerical solution of the governing PDE's. As an illustration of the method, the time development of the planar Couette flow is studied for two molecular kinetic models with finite extensibility, namely the Finitely Extensible Nonlinear Elastic (FENE) and FENE-Peterlin (FENE-P) models.P) models.

• 대한기계학회논문집B
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• 제41권6호
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• pp.429-434
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• 2017

분자-연속체 하이브리드 기법은 연속체 유체역학으로 예측하기 어려운 마이크로/나노 스케일 유동에 대해 개발되고 발전해 왔다. 분자동역학은 고체표면 주변 영역에서 사용되고, 나머지 영역에서는 나비아스톡스 방정식이 사용된다. 본 연구에서는 나노채널에서 고체-액체 상호작용과 표면 거칠기의 영향을 연구하기 위해 분자-연속체 하이브리드 기법을 이용하여 쿠에트 유동을 해석하였다. 우리는 고체-액체 상호작용 힘인 표면 에너지와 표면 거칠기가 유동의 표면 경계조건에 영향을 주는 것을 발견하였다. 표면 에너지가 낮을 때에는 유동이 고체 표면에서 미끄러짐이 발생하였고, 표면 에너지가 증가함에 따라 미끄러짐의 크기가 감소하였다. 표면 에너지가 높을 때에는 로킹(locking) 경계조건이 형성되었다. 또한 표면 거칠기는 유동이 고체 표면에서 미끄러지는 것을 방해하여 로킹 경계조건이 잘 형성되도록 영향을 주었다.

• Journal of the Korean Wood Science and Technology
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• 제49권1호
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• pp.1-13
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• 2021

This study was conducted to investigate the effects of the synthesis method, melamine content, and GPC parameters (such as flow rate, column-detector temperature, and sample injection temperature) on the molecular weight of melamine-urea-formaldehyde (MUF) resins. Two different synthesis methods were employed. In the first method, MUF-A resins were synthesized by simultaneously reacting urea, formaldehyde, and melamine (5%, 10%, and 20%) using the reaction of alkaline-acid-alkaline steps under controlled temperature and viscosity. In the second method, MUF-B resins were synthesized by first reacting melamine at the same levels with formaldehyde and then by adding urea. The highest weight average molecular weight (Mw) of MUF-A resins was found at 10% melamine content when the flow rate was 0.3 and 0.8 ml/min; Mw decreased slightly at 20% melamine content. The results showed that Mw increased with an increase in the melamine content when the flow rate was 0.5 and 1.0 ml/min. In addition, Mw was the highest when the flow rate, column-detector temperature, and injection temperature were 0.3 ml/min, 50℃, and 25℃, respectively. On the contrary, MUF-B resins had greater Mw and number average molecular weight (Mn) than MUF-A resins. Overall, Mw and Mn increased as the melamine content increased. The optimal GPC parameter for MUF resins was determined as follows: a flow rate of 0.5 ml/min, a column-detector temperature of 50℃, and a sample injection temperature of 50℃.

• Biotechnology and Bioprocess Engineering:BBE
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• 제8권2호
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• pp.64-75
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• 2003

Aptamers are functional nucleic acids that can specially bind to proteins, peptides, amino acids. nucleotides, drugs, vitamins and other organic and inorganic compounds. The aptamers are identified from random DNA or RNA libraries by a SELEX (systematic evolution of ligands by exponential amplification) process. As aptamers have the advantage, and potential ability to be released from the limitations of antibodies, they are attractive to a wide range of therapeutic and diagnostic applications. Aptamers, with a high-affinity and specificity, could fulfil molecular the recognition needs of various fields in biotechnology. In this work, we reviewed some aptamer Selection techniques, properties, medical applications of their molecules and their biotechnological applications, such as ELONA (enzyme linked oligonucleotide assay), flow cytometry, biosensors, electrophoresis, chromatography and microarrays.

• Bulletin of the Korean Chemical Society
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• 제27권9호
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• pp.1433-1438
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• 2006

An AsFlFFF channel was designed and built, and then tested for analysis of pullulans and proteins. Pullulans and proteins having various nominal molecular weights were injected at various conditions of the cross-flow rate ($F_c$) and the channel-out flow rate ($F_{out}$). The retention (measured by the retention ratio R) and the zone broadening (measured by the plate height H) were measured, and then compared with theory. When the incoming flow rate, $f_{in}$ (and thus $F_{out}$) was varied with $F_c$ fixed at 2.5 mL/min, the plate height measured for the pullulan with nominal molecular weight (M) of about 100,000 showed the trend expected by the longitudinal diffusion theory (H decreases with increasing flow rate). In contrast, when $F_{out}$ was varied with the flow rate ratio, $F_c/F_{out}$, fixed constant at 5, the plate height measured for the same sample showed the trend expected from the non-equilibrium theory (H increases with increasing flow rate). Calibration plots (log D vs. log M) obtained with pullulans and proteins were not coincide, probably due to the difference in molecular conformation, suggesting the analysis of pullulans and proteins using AsFlFFF requires independent calibration. It was found that the linearity of the protein-calibration plot was improved by using a buffer solution as the carrier.

• Korea-Australia Rheology Journal
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• 제20권2호
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• pp.89-94
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• 2008

To satisfy good mechanical and optical properties of polymer-coated film products, it will be indispensable to elucidate the molecular orientation of polymer chains within coating liquids in coating flows. Using hybridized numerical method between computational fluid dynamics (CFD) and Brownian dynamics (BD) simulations can provide the useful information for the better quality control of coated films. Flexible polymer chains, e.g., ${\lambda}$-DNA molecules here, change their conformation according to the flow strength and the flow type. The molecular conformation within the coated film on the web or substrate is quite different, because the polymer chains experience the complicated flow strength and flow types in flow field. Especially in the slot coating flow, these chains are more extended by the extension-like flow field generated in the free surface curvature just beyond the downstream die region. Also, the polymer chain extension beneath the free surface can be affected by the die geometry, e.g., the coating gap, changing flow field.

• 한국소성가공학회:학술대회논문집
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• 한국소성가공학회 2003년도 추계학술대회논문집
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• pp.347-354
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• 2003

The dynamics of fluid flow through nanomachines is completely different from that of continuum. In this study, molecular dynamics simulations were performed for the flow of helium, neon, argon inside carbon(graphite) nanotubes of several sizes. The fluid was introduced into the nanotube at a given initial velocity according to given temperature. Diffusion coefficients were evaluated by Green-Kubo equation derived from Einstein relationship. The behaviour of the fluid was strongly dependent on the density of fluid and tube diameter, not on the tube length. It was found that the diffusion Coefficients increased With decreasing the density of molecules and increasing the diameter and temperature.

• 한국고분자학회:학술대회논문집
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• 한국고분자학회 2006년도 IUPAC International Symposium on Advanced Polymers for Emerging Technologies
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• pp.206-206
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• 2006

Polymer induced turbulent drag reduction achieved by adding minute amounts of high molecular weight DNAs in aqueous solution was investigated using a rotating disk apparatus. The DNAs in this study include ${\lambda}-DNA$ and calf-thymus (CT) DNA. By putting emphasis on effect of CT-DNA concentration, its DR characteristics were compared with that of ${\lambda}-DNA$ possessing monodisperse molecular weight characteristics based on both DR efficiency and a mechanical degradation under turbulence. The DNA chains having much higher molecular size than that of ${\lambda}-DNA$ are observed to be more susceptible to mechanical degradation in a turbulent flow. This result was verified via electrophoresis. Furthermore, the coil to globule phase transition of DNA was also investigated under a turbulent flow.

• Applied Science and Convergence Technology
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• 제25권4호
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• pp.67-72
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• 2016

This article describes an electrical network analysis (ENA) method to calculate the pressure distribution of a vacuum system in a molecular flow regime. The vacuum system was modeled using electrical components. For an accurate analysis, a complexly combined pipe model, excluding entrance conductance, was employed and the pressure distribution was simulated using ENA. A vacuum system comprising three vacuum pumps was used for simplicity. In addition, the ENA results were compared with results from finite element analysis (FEA) and experimental measurements. The pressure distribution profiles estimated from ENA, performed using the LTSpice IV software, were in agreement with FEA and experimental results.