• 제목/요약/키워드: Molecular Communication

검색결과 231건 처리시간 0.033초

로진변성 페놀수지의 Varnish 제조조건에 따른 물성 변화에 관한 연구 (A Study on the Physical Properties according to Varnish Cooking Conditions of Phenolic Modified Rosin Ester)

  • 정순기;김성빈
    • 한국인쇄학회지
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    • 제24권2호
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    • pp.11-24
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    • 2006
  • The Lithographic ink is composed of pigment, vehicle and additives. In especially, the vehicle is the most important element and consist of vegetable oils, mineral oils and resins. Varnishes have to resist certain forms of chemical and physical attack during ink manufacturing process and printing process So this varnish cooking is very important. In this paper, effects of cooking conditions of varnish using phenolic modified rosin ester on physical properties of the vehicle were studied. The varnish cooked according to temperature and time were compared in order of average molecular weight by the GPC method. and the rheological properties were found by rotational rheometer. And the emulsion behavior were compared by high speed emulsification tester which were set on 1200 rpm and $40^{\circ}C$ temperature (Novomatics Lithotronic). We displayed viscosity against tack(Inkometer Thwing-Albert M-106) by diagram.

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Synapses in neurodegenerative diseases

  • Bae, Jae Ryul;Kim, Sung Hyun
    • BMB Reports
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    • 제50권5호
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    • pp.237-246
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    • 2017
  • Synapse is the basic structural and functional component for neural communication in the brain. The presynaptic terminal is the structural and functionally essential area that initiates communication and maintains the continuous functional neural information flow. It contains synaptic vesicles (SV) filled with neurotransmitters, an active zone for release, and numerous proteins for SV fusion and retrieval. The structural and functional synaptic plasticity is a representative characteristic; however, it is highly vulnerable to various pathological conditions. In fact, synaptic alteration is thought to be central to neural disease processes. In particular, the alteration of the structural and functional phenotype of the presynaptic terminal is a highly significant evidence for neural diseases. In this review, we specifically describe structural and functional alteration of nerve terminals in several neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Amyotrophic lateral sclerosis (ALS), and Huntington's disease (HD).

Bacterial Outer Membrane Vesicles as a Delivery System for Virulence Regulation

  • Yoon, Hyunjin
    • Journal of Microbiology and Biotechnology
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    • 제26권8호
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    • pp.1343-1347
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    • 2016
  • Outer membrane vesicles (OMVs) are spherical nanostructures that are ubiquitously shed from gram-negative bacteria both in vitro and in vivo. Recent findings revealed that OMVs, which contain diverse components derived from the parent bacterium, play an important role in communication with neighboring bacteria and the environment. Furthermore, nanoscale proteoliposomes decorated with pathogen-associated molecules attract considerable attention as a non-replicative carrier for vaccines and drug materials. This review introduces recent advances in OMV biogenesis and discusses the roles of OMVs in the context of bacterial communication and virulence regulation. It also describes the remarkable accomplishments in OMV engineering for diverse therapeutic applications.

e-Organ Simulator 를 위한 Kepler 기반 협업 시스템 (Kepler based Collaborative System for e-Organ Simulator)

  • 박상수;한영주;김동현;윤찬현;심은보;노경태;남기엽
    • 한국정보처리학회:학술대회논문집
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    • 한국정보처리학회 2010년도 춘계학술발표대회
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    • pp.255-258
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    • 2010
  • 계산 집약적인 다양한 응용 프로그램들이 서로 유기적으로 통합되어 결과를 도출하는 컴퓨팅 환경에서는 응용들을 관리하기 위한 효과적인 워크플로우 기법과 컴퓨팅 자원관리 기술이 필요하다. 본 논문에서는 인체 생리기능 단위들을 모사한 신약개발 시뮬레이션을 지원하기 위한 OSICC (e-Organ Simulator-Integrated Cyber Computing) 시스템의 협업 기능을 평가한다. 제안하는 시스템은 워크플로우 관리자를 이용하여 시뮬레이션의 객체간 자원관리를 최적화하고 있으며, 프로토타입으로 구현되어 협업 컴퓨팅을 지원하는 OSICC 시스템에서 효율성을 확인하였다.

PD184352 Releases the Regular Hypoxic Reversible DNA Replication Arrest in T24 Cells

  • Martin, Leenus
    • BMB Reports
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    • 제40권6호
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    • pp.895-898
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    • 2007
  • The oxygen dependent regulation of DNA replication is an essential property of proliferating mammalian cells. In human T24 bladder cancer cells, several hours of hypoxia leads to reversible DNA replication arrest and re-entry of oxygen induces a burst of replication initiation. This short communication provides strong evidence that PD184352 initiates DNA replication in living hypoxic cells without elevating the oxygen level. PD184352 releases the regular hypoxic replicon arrest, however, at a low intensity compared to the effect of reoxygenation. Moreover, PD184352 shows no effect on normoxically incubated as well as reoxygenated T24 cells.

NEW POLYIMIDES: SYNTHESIS, PROPERTIES AND POTENTIAL APPLICATION

  • Kravtsova, V.D.;Zhubanov, B.A.;Bekmagambetova, K.H.
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 1998년도 춘계학술대회 논문집
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    • pp.481-483
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    • 1998
  • The problem of production of new materials based on polyheteroarylenes and other polymers combining good mechanical and dielectric properties. radiation and chemical stability with heat- and thermal stability is related with the development of efficient synthesis technique of starting low-molecular compounds. Alicyclic dianhydrides are believed to be the promising monomers to synthesize various polymers.

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분자동역학과 확률회전동역학을 결합한 멀티스케일 모델링 기법 개발 (Development of Multiscale Modeling Methods Coupling Molecular Dynamics and Stochastic Rotation Dynamics)

  • 차광호;정영균
    • 정보과학회 컴퓨팅의 실제 논문지
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    • 제20권10호
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    • pp.534-542
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    • 2014
  • 멀티스케일 모델링은 시공간적으로 서로 다른 규모의 시스템을 다룰 수 있는 시뮬레이션 기법이다. 본 연구에서는 멀티스케일 모델링 연구의 일환으로 서로 다른 시뮬레이션 기법인 분자동역학과 확률회전동역학을 결합할 수 있는 방법을 제안한다. 분자동역학 프로그램 중 잘 알려진 오픈 소스인 LAMMPS를 기반으로 멀티스케일링 모델링을 구현하였으며 LAMMPS에서 정의한 제3자를 위한 표준 확장 방법을 따랐다. 제안된 방법에서는 확률회전동역학 모델을 기본으로 경계 영역은 분자동역학으로 해석 가능하게 하였고 심리스한 해석을 보장하기 위하여 중첩 영역과 정보 교환 영역을 함께 구현하였다. 예비실험을 수행한 결과, 제안된 멀티스케일 방법론이 기존 분자동역학 시뮬레이션 결과와 일치된 해석 결과를 보여주었으며 실행 시간 또한 단축시킬 수 있음을 확인하였다.

PC Network Cluster를 사용한 대규모 재료 시뮬레이션에 관한 연구 (A Study on a large-scale materials simulation using a PC networked cluster)

  • 최덕기;류한규
    • 한국항공우주학회지
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    • 제30권5호
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    • pp.15-23
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    • 2002
  • 분자 동역학 기법을 사용한 재료 파괴 시뮬레이션은 계산량의 방대함으로 인하여 극히 최근까지 활발한 연구가 진행되지 못하였으나 최근 컴퓨터의 성능향상으로 인하여 새로운 연구분야로 떠오르고 있다. 분자 동역학은 그 특성상 계산 집약적인 환경을 요구함으로 대규모의 연산을 위해서는 슈퍼컴퓨터나 클러스터(cluster)의 사용이 필수적이나 고가의 장비와 사용료로 인하여 많은 제한을 받아왔다. 본 연구에서는 PC를 사용하여 클러스터를 제작하고, 균열이 있는 시편을 사용하여 파괴현상에 대한 분자 수준의 거동을 시뮬레이션 하였으며, 클러스터의 노드(node) 수, 효율, 분자 수, 노드간의 통신시간 등의 상호관계를 파악하여 최적의 성능을 가진 클러스터를 구성하는 데 필요한 요소들을 분석하였다. 제작된 PC 클러스터를 사용하여 약 50,000개의 분자를 사용한 재료 파괴 시뮬레이션을 수행하였다.

Fabrication and Characterization of Dye-sensitized Solar Cells based on Anodic Titanium Oxide Nanotube Arrays Sensitized with Heteroleptic Ruthenium Dyes

  • Shen, Chien-Hung;Chang, Yu-Cheng;Wu, Po-Ting;Diau, Eric Wei-Guang
    • Rapid Communication in Photoscience
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    • 제3권1호
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    • pp.16-19
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    • 2014
  • Anodic self-organized titania nanotube (TNT) arrays have a great potential as efficient electron-transport materials for dye-sensitized solar cells (DSSC). Herewith we report the photovoltaic and kinetic investigations for a series of heteroleptic ruthenium complexes (RD16-RD18) sensitized on TNT films for DSSC applications. We found that the RD16 device had an enhanced short-circuit current density ($J_{SC}/mAcm^{-2}=15.0$) and an efficiency of power conversion (${\eta}=7.2%$) greater than that of a N719 device (${\eta}=7.1%$) due to the increasing light-harvesting and the broadened spectral features with thiophene-based ligands. However, the device made of RD17 (adding one more hexyl chain) showed smaller $J_{SC}(14.1mAcm^{-2})$ and poorer ${\eta}(6.8%)$ compare to those of RD16 due to smaller amount of dye-loading and less efficient electron injection for the RD17 device than for the RD16 device. For the RD18 dye (adding one more thiophene unit and one more hexyl chain), we found that the device showed even lower $J_{SC}(13.2mAcm^{-2}) $ that led to a poorest device performance (${\eta}=6.2%$) for the RD18 device. These results are against to those obtained from the same dyes sensitized on $TiO_2$ nanoparticle films and they can be rationalized according to the electron transport kinetics measured using the methods of charge extraction and transient photovoltage decays.