• Title/Summary/Keyword: Molecular Characteristics

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Experimental Models for SARS-CoV-2 Infection

  • Kim, Taewoo;Lee, Jeong Seok;Ju, Young Seok
    • Molecules and Cells
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    • v.44 no.6
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    • pp.377-383
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    • 2021
  • Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) is a novel virus that causes coronavirus disease 2019 (COVID-19). To understand the identity, functional characteristics and therapeutic targets of the virus and the diseases, appropriate infection models that recapitulate the in vivo pathophysiology of the viral infection are necessary. This article reviews the various infection models, including Vero cells, human cell lines, organoids, and animal models, and discusses their advantages and disadvantages. This knowledge will be helpful for establishing an efficient system for defense against emerging infectious diseases.

What is Epigenomics and how it will be applied to the food industry? (Epigenomics는 무엇이며 식품산업에 어떻게 응용될 것인가?)

  • Yoo, Jin Young;Han, Ga Eun;Lee, Jong Hun
    • Food Science and Industry
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    • v.50 no.1
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    • pp.11-15
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    • 2017
  • Epigenomics is a study that analyzes and quantifies various epigenetic alterations that affect gene expressions in cells from the viewpoint of collective characteristics on biological molecular pools. DNA methylation and histone modification in cells can induce the epigenetic alterations. Especially, epigenetic alterations influenced by external factors as ingested foods and other environmental factors have been examined in the whole genome regions, which provide accumulated data of altered regions or patterns of global genome, Statistical analyses of these regions or patterns enables us to correlate epigenomic changes with human diseases in the whole genome region. Finding meaningful regulators is a major concern of epigenomic research in recent years, and these results will give the food industry an important clue to future food

Plasticity of Amorphous Alloys: 1. Homogeneous Deformation (비정질 합금의 소성 1: 균일변형)

  • Park, Kyoung-Won;Lee, Chang-Myeon;Lee, Jae-Chul
    • Korean Journal of Metals and Materials
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    • v.47 no.11
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    • pp.759-772
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    • 2009
  • Amorphous alloys, in addition to being promising materials for a variety of practical applications, provide an excellent test bed for evaluating our understanding of the underlying physics on deformation in amorphous solids. Like many amorphous materials, amorphous alloys can exhibit either homogeneous or inhomogeneous deformation depending on the stress level. The mode of deformation has a strong influence on whether the material behavior is classified as ductile or brittle. It was observed that the characteristics of these deformations are largely dependent on the atomic-scale structures of the alloys and determine the amount of the plastic deformation prior to failure. In this study, the structural features that control the homogeneous deformation of amorphous alloys are outlined on the basis on experiments and molecular dynamics simulations.

First Report on Plum Pocket Caused by Taphrina deformans in South Korea

  • Oh, Nam Kwon;Hassan, Oliul;Chang, Taehyun
    • Mycobiology
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    • v.48 no.6
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    • pp.522-527
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    • 2020
  • Plum pocket caused by the dimorphic ascomycetous fungi, Taphrina spp., results in unsightly malformations and crop loss. In 2016, Japanese plums (Prunus salicina Lindl.) with plum pocket symptoms were found in Gimcheon. Three isolates were collected from symptomatic P. salicina fruits and identified as Taphrina deformans based on morphological characteristics and molecular sequence analysis of including internal transcribed space (ITS) and the mitochondrial small ribosomal subunit (SSU) regions of the three isolates. Pathogenicity test on plum fruits confirmed that, the present T. deformans isolates are causal agent of plum pocket. To the best of our knowledge, this is the first report of plum pocket caused by T. deformans in South Korea.

Macruropyxis fraxini on Fraxinus rhynchophylla: Confirmation in the Korean Peninsula after 82 Years and the First Record in South Korea

  • Jung, Bok-Nam;Choi, Young-Joon;Shin, Hyeon-Dong;Park, Ji-Hyun
    • Mycobiology
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    • v.48 no.6
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    • pp.518-521
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    • 2020
  • Macruropyxis fraxini has been recorded on several species of Fraxinus in China, Japan, Russia (Far East), and North Korea since its first recorded observation as a rust fungus on F. rhynchophylla in Jilin, China, in 1899. In the Korean Peninsula, the rust fungus was first recorded on F. rhynchophylla in 1935, based on four specimens collected at Mt. Kumgangsan, Gangwondo Province, in the North Korean territory. We confirmed this rust in the Korean Peninsula after 82 years. The rust fungus was identified based on morphological characteristics and a molecular phylogenetic analysis. This is the first record of M. fraxini in South Korea.

Taxonomical Study of Noteworthy Species of Botryosphaeria in Japan

  • Hattori, Yukako;Ando, Yuho;Sasaki, Atsuko;Uechi, Nami;Nakashima, Chiharu
    • Mycobiology
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    • v.49 no.2
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    • pp.122-132
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    • 2021
  • The reexamination of the fungal genus Botryosphaeria on 12 plant species of 10 families was carried out based on molecular phylogenetic analyses using the regions of translation elongation factor 1-α, β-tubulin, DNA-directed RNA polymerase II subunit, and internal transcribed spacer region of rDNA and morphological characteristics. Japanese isolates were divided into five clades and include Botryosphaeria dothidea, B. qingyuanensis, B. sinensis, and Botryosphaeria spp. Two species, B. qingyuanensis and B. sinensis have been newly added to the Japanese mycoflora, but their host plants are not specified. Botryosphaeria tenuispora isolated from Leucothoe fontanesiana and insect galls on fruits of Aucuba japonica has been proposed as a new species.

Report on a New Truffle Species, Tuber koreanum sp. nov., from Korea

  • Park, Hyeok;Gwon, Ju-Hui;Lee, Jong-Chul;Eom, Ahn-Heum
    • Mycobiology
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    • v.49 no.6
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    • pp.527-533
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    • 2021
  • The truffle and ectomycorrhizal roots formed by Tuber sp. were collected from the rhizosphere of Quercus aliena in Korea. The morphological characteristics of the ascoma, and molecular phylogenetic analysis using sequences from the internal transcribed spacer (ITS) and large subunit (LSU) of ribosomal DNA, translation elongation factor 1-alpha (TEF), and RNA polymerase second largest subunit (RPB2) regions confirmed the distinct morphology of the truffle. This truffle belongs to a monophyletic clade among the other Tuber species in the phylogeny. This study describes the truffle, Tuber koreanum, as a new species reported from Korea.

A New Record of Aphid Parasitoid Wasp Ephedrus lacertosus (Hymenoptera: Braconidae: Aphidiinae) from South Korea

  • Kim, Sangjin;Kim, Yeongmo;Kim, Hyojoong
    • Animal Systematics, Evolution and Diversity
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    • v.38 no.4
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    • pp.263-266
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    • 2022
  • The genus Ephedrus Haliday, 1833 is a large taxon of Aphidiinae, consisting of 48 valid species in the world. This genus is considered to be important as a biological control agency, which includes solitary koinobiont parasitoids on aphids. One of its interesting characteristics is both male and female have 11-segmented antennae. In previous study, this genus was subdivided into three subgenus, Breviephedrus, Ephedrus and Fovephedrus, based on molecular and morphological characters. In this study, one Ephedrus species is firstly recorded from South Korea. Since it has been collected from Geumsan-gun in 2005 and deposited as dried specimen at Naturalis Biodiversity Center in Netherland, we recently confirmed it. Description and illustrations of the E. lacertosus are provided.

New Record of Chlorophthalmus nigromarginatus (Aulopiformes: Chlorophthalmidae) from Korea (한국산 파랑눈매퉁이과(홍메치목) 어류 1 미기록종, Chlorophthalmus nigromarginatus)

  • Jang, Jae-hoon;Lee, Yu-Jin;Kim, Jin-Koo
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.55 no.5
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    • pp.730-735
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    • 2022
  • Two specimens of Chlorophthalmus nigromarginatus Kamohara, 1953 (51.02 mm, 66.04 mm in standard length) belonging to the family Chlorophthalmidae were collected on February 8, 2022 in the eastern Jeju-do Island, Korea using a bottom trawl. The species has the following morphological characteristics: snout length almost the same as orbit diameter, bump absent on predorsal, caudal fin with posterior black margin. C. nigromarginatus is morphologically very similar to C. acutifrons but can be distinguished by caudal fin with black margin (C. acutifrons has no black margin). Molecular analyses showed that our specimens almost matched with C. nigromarginatus according to mtDNA 16S rRNA sequences (99.8%). Therefore, we propose a new Korean name for C. nigromarginatus, "Geom-eun-kko-ri-pa-rang-nun-mae-tung-i".

New Record of Chinook Salmon, Oncorhynchus tshawytscha (Walbaum, 1792) (Salmoniformes: Salmonidae) from Sokcho, Korea (한국산 연어과(Salmonidae) 어류 1미기록종, Oncorhynchus tshawytscha(Walbaum, 1792))

  • Lee, Yu-Jin;Kim, Jin-Koo
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.55 no.5
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    • pp.736-741
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    • 2022
  • A single specimen (91.5 cm standard length) of the salmonid species, Oncorhynchus tshawytscha (Walbaum, 1792) was collected on April 19, 2022 in Sokcho-si, Gangwon-do, Korea. O. tshawytscha has the following morphological characteristics: base of lower jaw teeth is black, black spots are scattered on the dorsal section of body, and the edge of caudal fin is black. Although the species is morphologically similar to Oncorhynchus kisutch, O. tshawytscha differs from it in having black spots on the caudal fin. Molecular analysis results based on mitochondrial cytochrome c oxidase subunit I (COI) sequences showed that our specimen perfectly matched with the COI sequences of O. tshawytscha registered at the NCBI. Therefore, we suggest the new Korean name 'Wang-yeon-eo' for O. tshawytscha.