• Journal of Advanced Navigation Technology
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• v.13 no.3
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• pp.311-318
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• 2009

This paper shows the research about the development of software receiving platform processing GPS/Galileo L1/E1/E5a signal. Various researches for new GNSS signal character are possible using software receiving platform by facile program code modification. In addition, the program that processes GPS and Galileo signal integration is expected to help developing integration of receiver algorithm that deal with new various GNSS signal. In this paper, it is introduced the structure of GPS/Galileo receiving platform using sampled IF data as a program input. The function of the software platform embodied using MATLAB tool is tested by live data from Galileo test satellites. The software platform is modulated according to their roll and function. Each module is able to use selective function on GNSS signal.

• Journal of the Economic Geographical Society of Korea
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• v.7 no.2
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• pp.261-281
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• 2004

The location of auto industry in Jeon-buk is due to the strategies for secure a low-priced industrial site of the auto assembly companies, which attained to quantitative growth stage in the early part 1990's, and the regional balanced development policy by the location of leader enterprise of the government. As a consequence of the reversal development pattern that is located the auto parts firm after locating the auto assembly companies, the Jeon-buk auto industry has many structural vulnerability. First, because of the lack development of auto parts industries, the auto assembly companies located in Jeon-buk are dependent many auto parts at a external region. Second, most of auto parts firm belongs to the singular assembly company exclusively. And the majority of auto parts industries are the low value-added products that are necessary a simple labor power. Third, the agglomeration undeveloped of associated industries with automobile caused a low competitiveness of invitation a manufacturing company as against other provinces. For a regional economic development by the auto industry, it is necessary a flexible regional structure of production through an agglomeration of associated industries. The geographical proximity between an assembly company and a parts firms is an important locational factor with the induction of Just-in-Time production system and a modularization in the auto industry. And a modularization applies to more new factory than the existing factories. So that, Jeon-buk self-government has to create an amicable industrial environment, try to attract an auto parts enterprises and plan an agglomerated industrial complex that is able to supply a parts modulated to assembly company.

• Korean Journal of Biological Psychiatry
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• v.19 no.2
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• pp.71-76
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• 2012

Objectives : Novelty seeking (NS) represents a dopaminergically modulated tendency toward frequent exploratory activity. Considering the reports showing the relationship between exploratory activity and amygdalar function and structure, and the fact that amygdala is one of the key structures that constitute the dopaminergic pathway in the brain, amygdala might be closely related to NS tendencies. Amygdalar subregional analysis method, which has the enhanced sensitivity compared to the volumteric approach would be appropriate in investigating the subtle differences of amygdalar structures among healthy individuals. The aim of the current study was to examine whether amygdalar subregional morphometric characteristics are associated with the NS tendencies in healthy adults using the amygdalar subregional analysis method. Methods : Twenty-six healthy adults (12 males, 14 females ; mean age $29.8{\pm}6.2$ years) were screened for eligibility. All subjects completed the Korean version of the Temperament and Character Inventory (TCI) and underwent high-resolution brain magnetic resonance imaging. Individuals were divided into 2 groups according to NS scores of the TCI. Results : Individuals of the high NS group had significantly larger laterobasal subregions in right amygdala, after adjustment with the brain parenchymal volumes. Sensitivity analyses for each potential confounding factor such as age, education years and Hamilton Depression Rating Scale (HDRS) scores demonstrated consistent results. Conclusions : This study suggests that NS differences are associated with the laterobasal subregion of the amygdala.

• Molecules and Cells
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• v.39 no.8
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• pp.594-602
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• 2016

Alkyl hydroperoxide reductase subunit C from Pseudomonas aeruginosa PAO1 (PaAhpC) is a member of the 2-Cys peroxiredoxin family. Here, we examined the peroxidase and molecular chaperone functions of PaAhpC using a site-directed mutagenesis approach by substitution of Ser and Thr residues with Cys at positions 78 and 105 located between two catalytic cysteines. Substitution of Ser with Cys at position 78 enhanced the chaperone activity of the mutant (S78C-PaAhpC) by approximately 9-fold compared with that of the wild-type protein (WT-PaAhpC). This increased activity may have been associated with the proportionate increase in the high-molecular-weight (HMW) fraction and enhanced hydrophobicity of S78C-PaAhpC. Homology modeling revealed that mutation of $Ser^{78}$ to $Cys^{78}$ resulted in a more compact decameric structure than that observed in WT-PaAhpC and decreased the atomic distance between the two neighboring sulfur atoms of $Cys^{78}$ in the dimer-dimer interface of S78C-PaAhpC, which could be responsible for the enhanced hydrophobic interaction at the dimer-dimer interface. Furthermore, complementation assays showed that S78C-PaAhpC exhibited greatly improved the heat tolerance, resulting in enhanced1 survival under thermal stress. Thus, addition of Cys at position 78 in PaAhpC modulated the functional shifting of this protein from a peroxidase to a chaperone.

• Journal of Life Science
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• v.26 no.12
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• pp.1367-1375
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• 2016

Cilostazol is known to be a selective inhibitor of phosphodiesterase III and is generally used to treat stroke. Our previous findings showed that cilostazol enhanced capillary density through angiogenesis after focal cerebral ischemia. Angiogenesis is an important physiological process for promoting revascularization to overcome tissue ischemia. It is a multistep process consisting of endothelial cell proliferation, migration, and tubular structure formation. Here, we examined the modulatory effect of cilostazol at each step of the angiogenic mechanism by using human brain microvascular endothelial cells (HBMECs). We found that cilostazol increased the migration of HBMECs in a dose-dependent manner. However, it did not enhance HBMEC proliferation and capillary-like tube formation. We used a cDNA microarray to analyze the mechanisms of cilostazol in cell migration. We picked five candidate genes that were potentially related to cell migration, and we confirmed the gene expression levels by real-time PCR. The genes phosphoserine aminotransferase 1 (PSAT1) and CCAAT/enhancer binding protein ${\beta}$ ($C/EBP{\beta}$) were up-regulated. The genes tissue factor pathway inhibitor 2 (TFPI2), retinoic acid receptor responder 1 (RARRES1), and RARRES3 were down-regulated. Our observations suggest that cilostazol can promote angiogenesis by promoting endothelial migration. Understanding the cilostazol-modulated regulatory mechanisms in brain endothelial cells may help stimulate blood vessel formation for the treatment of ischemic diseases.

• Smart Media Journal
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• v.7 no.1
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• pp.37-44
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• 2018

Utilizing sequence control and numerical computing, embedded devices are used in a variety of automated systems, including those at industrial sites, in accordance with their control program. Since embedded devices are used as a control system in corporate industrial complexes, nuclear power plants and public transport infrastructure nowadays, deliberate attacks on them can cause significant economic and social damages. Most attacks aimed at embedded devices are data-coded, code-modulated, and control-programmed. The control programs for industry-automated embedded devices are designed to represent circuit structures, unlike common programming languages, and most industrial automation control programs are designed with a graphical language, LAD, which is difficult to process static analysis. Because of these characteristics, the vulnerability analysis and security related studies for industry automation control programs have only progressed up to the formal verification, real-time monitoring levels. Furthermore, the static analysis of industrial automation control programs, which can detect vulnerabilities in advance and prepare for attacks, stays poorly researched. Therefore, this study suggests a method to present a discussion on an industry automation control program designed to represent the circuit structure to increase the efficiency of static analysis of embedded industrial automation programs. It also proposes a medium term translation technology exploiting LLVM IR to comprehensively analyze the industrial automation control programs of various manufacturers. By using LLVM IR, it is possible to perform integrated analysis on dynamic analysis. In this study, a prototype program that converts to a logical expression type of medium language was developed with regards to the S company's control program in order to verify our method.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.13 no.10
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• pp.1089-1097
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• 2002

In this paper, the novel shipboard Active Phased Array Antenna(APAA) system for maritime mobile satellite communications is introduced. The antenna uses novel technologies like wide range hybrid tracking, single antenna elements with both of Rx and Tx, asymmetrical array structure, interference isolation between Rx and Tx, and error correction method from frequency scan effect. The antenna has single aperture for both of Rx and Tx with 32 $\times$ 4 two-dimensional array. The antenna has two beams. Its frequencies are 7.25 ~ 7.75 GHz for Rx and 7.9 ~ 8.4 GHz for Tx. The antenna gains are 35.4 dBi for Rx and 35.7 dBi for Tx, those are 54 % of efficiency. The electrically steering ranges are $\pm$35$^{\circ}$ of elevation direction and $\pm$4$^{\circ}$ of azimuth direction. The mechanical control ranges at hybrid tracking capability are continuous 360$^{\circ}$ of azimuth direction and $\pm$10$^{\circ}$ of elevation direction. The antenna has 2.2$^{\circ}$ of 3 dB beamwidth, -14 dB of sidelobe level, and 21 dB of cross-pol suppression. The antenna performance was measured by near field measurement set. Its system performance was tested on the ship motion simulator and with the satellite transponder simulator. The test result showed that its tracking error was within -3 dB from its peak gain under motion condition. The antenna system was tested by real modulated Direct Broadcasting Satellite(DBS) signals to check its communication processing function.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.44 no.7 s.361
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• pp.17-22
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• 2007

OFDM (Orthogonal Frequency Division Multiplexing) is a special case of multicarrier transmission, where a single data stream is transmitted over a number of lower-rate subcarrier. One of the main reasons to use OFDM is to increase robustness against frequency-selective fading or narrowband interference. Unfortunately, an OFDM signal consists of a number of independently modulated subcarriers, which can give a large PAPR (Peak-to-Average Power Ratio) when added up coherently. In this paper, we investigate the performance of a simple PAPR reduction scheme, which requires no change of a receiver structure or no additional information transmission. The approach we employed is clipping in the time and frequency domains. The time-domain clipping is carried out with a predetermined clipping level while the frequency-domain clipping is done within EVM (Error Vector Magnitude). This approach is suboptimal with lower computational complexity compared to the optimal method. This evaluation is carried out on the OFDM system with an nonlinear amplifier. The simulation results demonstrated that the PAPR reduction algorithm is one of ways to reduce the effects of the nonlinear distortion of an HPA (High Power Amplifier).

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.45 no.12
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• pp.42-48
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• 2008

Next generation wireless communication systems require RF transceivers that enable multiband/multimode operations. Polar transmitters are known as good candidates for high data rate systems such as EDGE (Enhanced Data Rates for GSM Evolution), WCDMA (Wideband Code Division Multiple Access), and WLAN (Wireless Local Area Network) because they can obtain high efficiency by using efficient switched-mode RF power amplifiers. In this paper, we investigate the performance of a simple peak windowing scheme for the OFDM (Orthogonal frequency Division Multiplexing) polar transmitter, which requires no change of a receiver structure or no additional information transmission. The approach we employed is to apply the peak windowing scheme to the amplitude modulated signals of the polar transmitter to reduce the PAPR (Peak-to-Average Power Ratio). The BER (Bit Error Rate) and EVM (Error Vector Magnitude) performances are measured for various window types and lengths. The simulation results demonstrate that the proposed algorithm mitigates out-of-band distortion introduced by clipping along with PAPR reduction.

• Proceedings of the Ginseng society Conference
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• 2002.10a
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• pp.96-112
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• 2002

In the present study, we have investigated the effects of centrally administered ginsenoside Rc or Rgl on the modulation of NMDA receptor and $GABA_A$ receptor binding in rat brain. The NMDA receptor binding was analyzed by quantitative autoradiography using $[^3H]MK-801$ binding, and $GABA_A$ receptor bindings were analyzed by using $[^3H]muscimol\;and\;[^3H]flunitrazepam$ in rat brain slices. Rats were infused with ginsenoside Rc or Rg1 ($10\;{\mu}g/10{\mu}l/hr$, i.c.v.) for 7 days, through pre-implanted cannula by osmotic minipumps (Alzet, model 2ML), The levels of $[^3H]MK-801$ binding were highly decreased in part of cortex and cingulated by ginsenoside Rc and Rgl. The levels of $[^3H]muscimol$ binding were strongly elevated in almost all regions of frontal cortex by the treatment of ginseoside Rc but decreased by ginsenoside Rg 1. However, the $[^3H]flunitrazepam$ binding was not modulated by ginsenoside Rc or ginsenoside Rgl infusion. These results suggest that prolonged infusion of ginsenoside could differentially modulate $[^3H]MK-801\;and\;[^3H]muscimol$ binding in a region-specific manner. Also, we investigated the influence of centrally administered ginsenoside on the regulation of mRNA levels of the family of NMDA receptor subtypes (NR1, NR2A, NR2B, NR2C) by in situ hybridization histochemistry in the rat brain. The level of NR1 mRNA is significantly increased in temporal cortex, caudate putamen, hippocampus, and granule layer of cerebellum in Rgl-infused rats as compared to control group. The level of NR2A mRNA is elevated in the frontal cortex. In contrast, it was decreased in CAI area of hippocampus in Rgl-infused rats. However, there was no significant change of NR1 and NR2A mRNA levels in Rc-infused rats. The level of NR2B mRNA is elevated in cortex, caudate putamen, and thalamus in both Rc- and Rg-infused rats. In contrast, NR2B level is decreased in CA3 in Rgl-infused rats. The level of NR2C mRNA is increased in the granule layer of cerebellum in only Rg1 but not Rc infused rats. These results show that structure difference of ginsenoside may diversely affect the modulation of expression of NMDA receptor subunit mRNA after infusion into cerebroventricle in rats.