• Journal of Korean Neurosurgical Society
• /
• 제46권4호
• /
• pp.322-327
• /
• 2009

Objective : Posterior lumbar interbody fusion (PLIF) is considered to have the best theoretical potential in promoting bony fusion of unstable vertebral segments by way of a load sharing effect of the anterior column. This study was undertaken to investigate the efficacy of PLIF with cages in chronic degenerative disc disease with Modic degeneration (changes of vertebral end plate). Methods : A total of 597 patients underwent a PLIF with threaded fusion cages (TFC) from 1993 to 2000. Three-hundred-fifty-one patients, who could be followed for more than 3 years, were enrolled in this study. Patients were grouped into 4 categories according to Modic classification (no degeneration : 259, type 1 : 26, type 2 : 55, type 3 : 11). Clinical and radiographic data were evaluated retrospectively. Results : The clinical success rate according to the Prolo's functional and economic outcome scale was 86% in patients without degeneration and 83% in patients with Modic degeneration. The clinical outcomes in each group were 88% in type 1, 84% in type 2, and 73% in type 3. The bony fusion rate was 97% in patients without degeneration and 83% in patients with Modic degeneration. The bony fusion rate in each group was 81% in type 1, 84% in type 2, and 55% in type 3. The clinical success and fusion rates were significantly lower in patients with type 3 degeneration. Conclusion : The PLIF with TFC has been found to be an effective procedure for lumbar spine fusion. But, the clinical outcome and bony fusion rates were significantly low in the patients with Modic type 3. The authors suggest that PLIF combined with pedicle screw fixation would be the better for them.

• Journal of Acupuncture Research
• /
• 제32권4호
• /
• pp.187-194
• /
• 2015

Objectives : The purpose of this study was to observe the correlation between modic type changes 2 and facet joint arthrosis. Methods : We randomly selected the 93 patients with Lumbar MRI films who had been admitted to Haeundae Jaseng Korean Medicine Hospital from January to June 2015. Modic type changes 2 and facet joint arthrosis data were collected and statistically analyzed. Results : In this study, if the findings of the MRI showed modic type changes 2, the cases of facet joint arthrosis increased. Conclusions : There was a significant correlation between modic type changes 2 and facet joint arthrosis.

• 대한정형외과학회지
• /
• 제56권4호
• /
• pp.283-293
• /
• 2021

퇴행성 추간판 질환은 전통적으로 수핵과 섬유륜의 변화에 따른 요통으로 생각되어 왔으나, 최근 연구들에서 추간판을 이루고 있는 상·하 종판의 변화가 추간판의 퇴행을 유발하고, 그 결과로 기계적 압박과 염증 반응에 의해 요통이 유발된다고 한다. 또한 최근에는 추체 골수-종판-수핵과 섬유륜을 하나의 단위로 생각하고, 그 연관성을 설명하고 있다. 종판이 손상되면 결국 추체, 수핵과 섬유륜의 퇴행성 변화를 가중시킨다. 이 과정에서 섬유륜에 가해지는 압박력이 증가하고, 염증성 매개 물질들에 의한 염증 반응이 일어나서, 동척추 신경(sinuvertebral nerve)과 기저추 신경(basivertebral nerve)이 자극을 받으면서 요통을 발생시킨다. 이런 변화가 만성화되면, 추체 내 골수에도 Modic 변화 같은 퇴행성 변화가 발생하게 된다. 결국, 퇴행성 추간판 질환은 추체 골수-종판-수핵과 섬유륜을 하나의 단위로 연관지어서 생각해야 할 필요가 있다. 그러므로 만성 요통 환자 진료 시에는 수핵과 섬유륜의 변화 소견뿐 아니라, 종판의 병변에 관심을 가질 필요가 있다고 생각된다.