• Bulletin of the Korean Chemical Society
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• 제35권12호
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• pp.3489-3494
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• 2014

In search of new antileukopenia agents, twenty dithiolopyrrolone derivatives were synthesized and evaluated for their leukocyte-increasing activities in normal mice. Among the synthesized compounds 4-23, compounds 5 and 6 showed significant leukocyte-increasing activity ( p < 0.01), and compounds 4, 9 and 16 had a moderate effect ( p < 0.05). Compound 5 also displayed stronger leukocyte-increasing activity than that of the positive recombinant human granulocyte colony stimulating factor (rhG-CSF). Above all, compound 5 would be a potential antileukopenia agent which deserved further research.

• 국제초고층학회논문집
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• 제1권3호
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• pp.221-228
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• 2012

Shanghai Tower is a super high-rise building of 632 m height with 'mega frame-core- outrigger truss' structure system. Due to the complexity and irregularity of structure, shaking table test was carried out to investigate its seismic performance. A 1/40 scaled test model was designed, built and tested on shaking table under earthquake of small, moderate and large levels. The experimental results showed that the structure can meet the requirements of Chinese codes and reach scheduled performance objectives. Elastic and plastic time-history analysis on the structure were carried out and the results were compared to experimental results. Based on the research results some suggestions were proposed to contribute favorable effect on the seismic capacity of the structure.

• 한방안이비인후피부과학회지
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• 제17권1호
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• pp.126-130
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• 2004

Objectives; Bioassay-directed fractionation of the dried roots of Salvia miltiorrhiza led to the isolation of abietane tanshinones, crptotanshinone and dihydrotanshinone. Methods: Their structures were elucidated using 1H-and 13C-NMR, UV, IR and mass spectral analysis. Result and Conclusions : These compounds exhibited a moderate antimicrobial activities against Staphylococcus epidemidis, Staphylococcus aureus, Staphylococcus pyogene. Actinobacillus actinomycetemcomitans, Escherichia coil, Enterbacter cloacae, Pseudomonas aeruginosa, Citrobacter freundii, and Samonella typhimurium.

• 디지털산업정보학회논문지
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• 제8권1호
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• pp.231-244
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• 2012

Consumer dissatisfaction and complaints make it difficult for online shopping mall to maintain existing customers and attract new customers, which may result in a direct profit loss. The primary purpose of this study is to investigate the relationship between customer dissatisfaction in terms of product-complaints and website complaints and complaint behaviors in terms of individual, public, and 3rd party complaint behaviors. Th results indicate that product-dissatisfaction is significantly related to the public and 3rd party complaint behaviors, but not the individual complaint behavior. Website dissatisfaction was not found to be significantly related to any complaint behavior. The moderate effect of sex and individual attitude on the relationship between customer dissatisfaction and complaint behaviors was also not considerable.

• Biomolecules & Therapeutics
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• 제1권1호
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• pp.109-120
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• 1993

Mechanisms for the hypocholesterolemic effetcs of $\beta$-glucan remain unclear. Rats were divided into 3 groups; normal control group, atherogenic group(oral administration of cholesterol 40 mg/kg/day and vitamin $D_2$320,000 IU/kg/day),${\beta}$-glucan treatment group(oral administration of atherogenic treatment and ${\beta}$-glucan 0.135 g/kg/day). The ${\beta}$-glucan treatment group showed moderate increases of serum lipids concentration compared with atherogenic group. In histopathological examination, aortas showed no critical lesions. The total fecal neutral sterols and bile acids excreted for 6 days was increased compared with both normal and atherogenic group. These result\ulcorner suggest that mechanisms for the hypocholesterolemic effect of ${\beta}$-glucan on rats were due to the inhibition of cholesterol absorption in the intestinal lumen and acceleration of cholesterol catabolism in the liver.

• Journal of Photoscience
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• 제6권2호
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• pp.61-65
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• 1999

The fluorescence properties and photoisomerization behavior of 1-(9-anthryl)-2-(n-quinolinyl)ethene (n-AQE, n=2-4) have been investigated in various solvents. t-3-AQE is strongly fluorescent, but does not accomplish photoisomerization, similar to parent hydrocarbon compound, t-1-(9-anthryl)-2-phenylethene (t-9-APE) or t-1-(9-anthryl)-2-(1-naphthyl)ethene (t-1-ANE). Fluorescence and photoisomerization oft-2-AQE and t-4-AQE are strongly affected by solvent polarity. Dependence of fluorescence quantum yield on the solvent polarity is moderate for t-2-AQE and large for t-4-AQE. In nonpolar solvent (in n-hexane), they exhibit relatively strong fluorescence, but do not isomerize to cis isomer on irradiation, even if inefficient isomerization is observed for t-4-AQE. However, as solvent polarity increases, their fluorescences become weak with efficient photoisomerization to corresponding cis isomer. Intramolecular charge-transfer excited state is presumed to contribute to photoisomerization. The S$_1$ decay parameters were found to be solvent-dependent due to the charge-transfer character of lowest S$_1$ state. In polar solvents, the activation barrier to twisting is reduced enhancing the isomerization of r-2-AQE and t-4-AQE in the singlet manifold.

• Journal of Chest Surgery
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• 제23권4호
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• pp.622-639
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• 1990

The use of aortic valve homograft has been developed since 1962 when Ross and Barratt - Boyes independently replaced a diseased aortic valve with an orthotopically inserted homograft valve. And also surgical treatment of complex congenital cardiac malformations utilizing homograft extracardiac conduit has been tried with better result than any other prosthetic material. The present study was undertaken to clarify the safety tissue viability, sterility, after following our protocol of procurement of heart, dissection of aortic and pulmonic homograft, sterilization, cryopreservation, thawing and dilution, and transplantation on experimental animal, sheep. Tissue viability of valve and great artery was assessed by tissue culture. Sterility was evaluated by bacterial and fungal culture. The method used was proven no deleterious effect on the integrity of the valve. Tissue culture of valve tissue before, and after cryopreservation process resulted that active fibroblast growth was observed from homograft sterilized with antibiotics. And culture of the transplanted homograft from sacrificed animal showed active fibroblast growth. Pathologic examination of implanted valve tissue from sacrificed sheep showed mild calcification and minor change, but there were moderate and severe calcification of wall of great arteries.

• Journal of Dental Anesthesia and Pain Medicine
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• 제18권4호
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• pp.261-265
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• 2018

Rett syndrome (RS) is a neurodevelopmental disorder characterized by loss of cognitive, motor, and social skills, epilepsy, autistic behavior, abnormal airway patterns, gastroesophageal reflux, nutritional problems, and severe scoliosis. Although girls with RS show normal or near-normal growth until 6-8 months, they lose their skills after that. The anesthetic management of these patients requires care because of all these clinical features. Especially in the postoperative period, prolonged apnea is common and extubation is delayed. In this case report, the effect of using sugammadex was presented in a 16-year-old girl with RS. The patient's all bimaxillary teeth and 4 wisdom teeth were extracted under general anesthesia in one session with minimal surgical trauma and moderate bleeding. Sugammadex can be a rapid and reliable agent for the reversal of the neuromuscular block in neurodegenerative patients.

• Asian-Australasian Journal of Animal Sciences
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• 제14권8호
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• pp.1062-1066
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• 2001

Studies were carried out on forty young bulls of the Hariana breed (around 18 months of age) selected on the basis of their dam's milk yield at the animal farm of CCS HAU, Hisar during the period 1993-1999. Since animals showed variation in capacity to work over prolonged periods, they were subjected to regimes of carting without load and with 8 qtls. of load for three hours. The study revealed that maximum change took place in the pulse rate, followed by respiration rate and rectal temperature. The mean fatigue score for pulling an empty cart ranged between 1.66 to 2.20 after two hours work, and 2.36 to 2.73 after three hours work. For a cart loaded with 8 qtls., the corresponding ranges were 2.90 to 3.36 and 3.40 to 4.10, respectively. These results indicated that the animals under experiment had the capacity to pull moderate load (8 qtls.) for about two hours without showing any serious effect on the ability to recover and soon to work again.

• 한국경영과학회지
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• 제22권1호
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• pp.159-182
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• 1997

This study is to establish the validity of EDI adoption model Korean Companies. The research model is hypothesized in the external factors of company directly affect on EDI adoaption and the internal factors of company moderately affect on the direct effect. The external factors of company consists of economic factors, organizational power factors, and technological factor. The internal factors of company consists of the size of the company, innovative tendency of the top management, and maturity of the information technology. In the result of data analysis-the data were collected from a total of 81 companies in 6 industries adopted variables are the existence of EDI standard, transaction frequency, inter-organizational bargaining power, and pressure from industry association. Also size of the company and innovative tendency of the top management in a company's internal factors were adopted as moderate variables.