• 제목/요약/키워드: Moderate Effect

검색결과 1,698건 처리시간 0.026초

The effect of L-carnosine on the rheological characteristics of erythrocytes incubated in glucose media

  • Nam, Jeong-Hun;Kim, Chang-Beom;Shin, Se-Hyun
    • Korea-Australia Rheology Journal
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    • 제21권2호
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    • pp.103-108
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    • 2009
  • Hemorheological properties are easily modified by glucose-induced oxidation and glycation. Carnosine, a naturally occurring dipeptide ($\beta$-alanyl-LFull-size image-histidine), has been recently proposed to act as an antioxidant as well as a free-radical scavenger. In the present study, we investigate its protective and rejuvenating effects in erythrocytes that are exposed to glucose-rich plasma. Erythrocytes that were incubated in glucose solutions were treated with different concentrations of carnosine and for different incubation times. Their hemorheological alterations were examined. The results reveal that the presence of carnosine effectively prevented these rheological alterations in a concentration-dependent manner in glucose-rich media. It is proposed that moderate concentrations of carnosine might be further explored as potential therapeutic agents for pathologies that involve hemorheological modification.

간호사의 공감피로와 소진과의 관계에서 공감만족과 사회적 지지의 효과 (Effects of Compassion Satisfaction and Social Support in the Relationship between Compassion Fatigue and Burnout in Hospital Nurses)

  • 염영희;김현정
    • 대한간호학회지
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    • 제42권6호
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    • pp.870-878
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    • 2012
  • Purpose: The purpose of this study was to identify the effects of compassion satisfaction and social support in the relationship between compassion fatigue and burnout among hospital nurses. Methods: The participants were 430 nurses working in general hospitals. Data were collected with self-administrated questionnaires and analyzed by hierarchical multiple regression. Results: (a) Compassion fatigue had a significant positive effect on burnout; (b) social support and compassion satisfaction had negative effects on burnout, and (c) social support and compassion satisfaction did not moderate the effects of compassion fatigue on burnout. Conclusion: These findings provide strong empirical evidence for the importance of compassion fatigue, compassion satisfaction and social support in explaining burnout of nurses. Also, it would be of great value to further define compassion fatigue and compassion satisfaction even though these concepts are not accepted in the realities of health care.

벽식 APT의 반응수정계수 추정에 관한 연구 (Evaluation of Response Modification Factors for Shear Wall Apartment Building)

  • 송정원;송진규;이수곤
    • 한국콘크리트학회:학술대회논문집
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    • 한국콘크리트학회 2001년도 봄 학술발표회 논문집
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    • pp.859-864
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    • 2001
  • For earthquake resistance design, a response modification factor is used to reduce the design strength and it reflects ductility, reserve strength, redundancy and damping effect. But this factor has not theoretical basis. In this study, two response modification factors are compared and analyzed for shear wall apartment building.; the one is introduced by ATC-19 Procedures, the other is suggested FEMA-273 and ATC-40 through nonlinear static analysis. For the results, ATC-19 procedure gives a reasonable estimation to R factor. But $R_{u}$ by using FEAM-273 and ATC-40 methods is estimated so small in case of a minor or moderate earthquake region. Due to this fact, response modification factor is smaller than suggested load criterion 3.0. So, it needs to decrease wall volume and reduce the global strength and system stiffness for proper ductile behavior matching to domestic load criterion.

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근린구매시설환경과 가정생산방식, 가정생산지지도와의 관계에 관한 연구 (A Study on the Relationship of the Neighborhood Facility Environment with the Way of Homeproduction and Homeproduction Supportability)

  • 차성란
    • 한국주거학회논문집
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    • 제6권1호
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    • pp.19-29
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    • 1995
  • This study is to analyze the effect of neighborhood commercial facilities on the homeproduction activities and the family expenditure(or household work time). For this purpose. data are collected by using questionnaires distributed to 522 housewives in Seoul. The results shows that in the highly goods-intensive environment. the way of homeproduction is goods-intensive. Market dependence of the family is affected by homeproduction predisposition. income. and husband's job. Household work dependence of the .family is affected by neighborhood facility environment. family type. income. and house value. Low home production supportability is apparent in the high family income. full-time housewives and low job status of housewife. On the other hand. high homeproduction supportability is apparent in the moderate income and high job status of housewife. As a result. housewives have much time and money resourses are not well supported by the neighborhood facility environment.

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Dr. Speech Science의 음성합성프로그램을 이용하여 합성한 정상음성과 병적음성(Pathologic Voice)의 음향학적 분석 (Acoustic Analysis of Normal and Pathologic Voice Synthesized with Voice Synthesis Program of Dr. Speech Science)

  • 최홍식;김성수
    • 대한후두음성언어의학회지
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    • 제12권2호
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    • pp.115-120
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    • 2001
  • In this paper, we synthesized vowel /ae/ with voice synthesis program of Dr. Speech Science, and we also synthesized pathologic vowel /ae/ by some parameters such as high frequency gain (HFG), low frequency gain(LFG), pitch flutter(PF) which represents jitter value and flutter of amplitude(FA) which represents shimmer value, and grade ranked as mild, moderate and severe respectively. And then we analysed all pathologic voice by analysis program of Dr. Speech Science. We expect that this synthesized pathologic voices are useful for understanding the parameter such as noise, jitter and shimmer and feedback effect to patient with voice disorder.

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아출(莪朮)의 Sesquiterpene 성분의 약물활성 (Pharmacological Activities of Sesquiterpenes from the Rhizomes of Curcuma zedoaria)

  • 신국현;윤기영;조태순
    • 생약학회지
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    • 제25권3호
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    • pp.221-225
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    • 1994
  • Pharmacological activities of two sesquiterpenes, curzerenone(I), and curcumenol(II) isolated from the rhizomes of Curcuma zedoaria being used as an aromatic stomachic in Chinese medicines were evaluated in rats and mice. Curzerenone (I), at 100mg/kg, p.o. showed a potent protective effect against HCl-ethanol induced gastric lesion in rats, and curcumenol(II), at the same dose level showed a CNS depressant action characterized by a potentiation of hexobarbital(HB)-induced narcosis. Both compounds showed a moderate analgesic action but did not exhibit a hypothermic action even at 200mg/kg dose level.

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Misalignment가 있는 유한한 선접촉 EHL 문제의 수치해석 (Numerical Analysis of Misaligned Finite Line Contacts EHL Problem)

  • 박태조
    • Tribology and Lubricants
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    • 제26권5호
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    • pp.263-271
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    • 2010
  • The rollers of cylindrical roller bearing are axially profiled to relieve high edge stress concentration caused by mainly their finite length and by misalignment. In this paper, a numerical analysis is carried to study the EHL of misaligned (tilted) rollers with axially profiled ends. Using a finite difference method with non-uniform grids and the Newton-Raphson method, the highly nonlinear EHL problems are systematically solved. Physically consistent solutions are obtained for moderate load, material parameters and very small misalignment. For different misalignment angles, contours and sectional plots of pressure and film shape near both edge regions are compared. The asymmetric pressure distributions and film shapes show that the EHL results of finite line contacts are highly dependent upon very small amounts of roller misalignment. Especially, the effect of misalignment on the EHL pressure distribution is much higher than the film shapes.

DELTA OPIOID ANALGESICS

  • Burks, Thomas F.
    • 한국응용약물학회:학술대회논문집
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    • 한국응용약물학회 1994년도 춘계학술대회 and 제3회 신약개발 연구발표회
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    • pp.50-62
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    • 1994
  • Opium, morphine and rotated natural and synthetic opiates have been used since antiquity, and to the present, for the relief of moderate and severe pain. Morphine and pharmacologically related drugs, however, produced an array of undesired or dangerous side effect that limit their use as analgesics. Prominent among the limiting side effects are constipation, respiratory depression, release of prolactin, and liability for the production of drug dependence. It was our aim to develop, if possible, a drug or class of drugs with analgesic activity similar to that of morphine, but without the serious side effects associated with morphine. Our overall strategy was to take advantage of advancing knowledge concerning multiple types of opioid receptors, to develop ligands selective for the delta type receptors, to determine whether delta receptor agonists offer advantages over mu agonists, then to design compounds with pharmacokinetic properties compatible with practical therapeutic application. All but the last of these objectives have been realized.

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초음파 관찰을 통한 비알콜성 지방간 환자 치험 1례 (A Case Study on A Patient with Non-Alcoholic Fatty Liver Disease (NAFLD) by Using Ultrasound)

  • 백태현
    • 대한한의학회지
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    • 제37권1호
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    • pp.151-157
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    • 2016
  • Objectives: The purpose of this study is to report the clinical effect of Shihosogan-tang extract on NAFLD through ultrasound. Methods: The patient was treated with Shihosogan-tang extract. We observed the changes in symptoms and ultrasound imaging on a patient with NAFLD. Results: After treatment, the symptoms of the patient with NAFLD were decreased and ultrasound imaging were improved from moderate to mild grade. Conclusion: The patient of NAFLD was improved in symptoms and ultrasound imaging.

The Effect of Eccentricity on Aerated Oil in High-Speed Journal Bearing

  • Chun, Sang Myung
    • KSTLE International Journal
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    • 제2권1호
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    • pp.1-11
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    • 2001
  • The influence of aerated oil on a high-speed journal bearing is examined by classical thermohydrodynamic lubrication theory coupled with analytical models for viscosity and density of air-oil mixture in fluid-film bearing. Convection to the walls and mixing with supply oil and re-circulating oil are considered. With changing eccentricity ratio, it is investigated the effects of air bubbles on the performance of a high-speed plain journal bearing. Just at the moderate eccentricity ratios, even if the involved aeration levels are not so severe and the entrained air bubble sizes are not so small, it is found that the bearing load and friction force may be changed so visibly for the high speed bearing operation.

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