• Fibers and Polymers
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• 제7권4호
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• pp.424-431
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• 2006

Roll drafting, a mechanical operation attenuating fiber bundles to an appropriate thickness, is an important operation unit for manufacturing staple yams. It influences not only the linear density regularity of the slivers or staple yams that are produced, but also the quality of the textile product and the efficiency of the thereafter processes. In this research, the dynamic states of the fiber bundle in the roll drafting zone were analyzed by simulation, based on the mathematical model that describes the dynamic behavior of the flowing bundle. The state variables are the linear density and velocity of the fiber bundles and we simulated the dynamics states of the bundle flow, e.g., the profiles of the linear density and velocity in the draft zone for various values of the model parameters and boundary conditions, including the initial conditions to obtain their influence on the dynamic state. Results showed that the mean velocity profile of the fiber bundle was strongly influenced by draft ratio and process speed, while the input sliver linear density has hardly affected the process dynamics. Velocity variance of individual fibers that could be supposed to be a disturbing factor in drafting was also influenced by the process speed. But the major disturbance occurred due to the velocity slope discontinuity at the front roll, which was strongly influenced by the process speed. Thickness of input sliver didn't play any important role in the process dynamics.

• IMMUNE NETWORK
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• 제20권4호
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• pp.33.1-33.19
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• 2020

We tested how adjuvants effect in a cancer vaccine model using an epitope derived from an autoactivation loop of membrane-type protease serine protease 14 (PRSS14; loop metavaccine) in mouse mammary tumor virus (MMTV)-polyoma middle tumor-antigen (PyMT) system and in 2 other orthotopic mouse systems. Earlier, we reported that loop metavaccine effectively prevented progression and metastasis regardless of adjuvant types and TH types of hosts in tail-vein injection systems. However, the loop metavaccine with Freund's complete adjuvant (CFA) reduced cancer progression and metastasis while that with alum, to our surprise, were adversely affected in 3 tumor bearing mouse models. The amounts of loop peptide specific antibodies inversely correlated with tumor burden and metastasis, meanwhile both T_H1 and T_H2 isotypes were present regardless of host type and adjuvant. Tumor infiltrating myeloid cells such as eosinophil, monocyte, and neutrophil were asymmetrically distributed among 2 adjuvant groups with loop metavaccine. Systemic expression profiling using the lymph nodes of the differentially immunized MMTV-PyMT mouse revealed that adjuvant types, as well as loop metavaccine can change the immune signatures. Specifically, loop metavaccine itself induces T_H2 and T_H17 responses but reduces T_H1 and T_reg responses regardless of adjuvant type, whereas CFA but not alum increased follicular T_H response. Among the myeloid signatures, eosinophil was most distinct between CFA and alum. Survival analysis of breast cancer patients showed that eosinophil chemokines can be useful prognostic factors in PRSS14 positive patients. Based on these observations, we concluded that multiple immune parameters are to be considered when applying a vaccine strategy to cancer patients.

• 한국자동차공학회논문집
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• 제25권1호
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• pp.11-18
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• 2017

In the present study, the low speed (4 km/h) crash behaviour of an aluminium bumper system was characterised by FE analyses based on the FMVSS 581, which regulates automotive bumpers. Two types of cross-sectional designs, i.e., Model 1, which contains a single rib and Model 2, double ribs, have been considered along with Al7021, 6082 and 6060 for the aluminium bumper back beam. Variations in thickness starting from 2 to 4 mm of the bumper system cross-section in the FE model was implemented in order to investigate the thickness effect on the bumper's crash behaviour.. Three kinds of design variables, namely, number of ribs, material and thickness, are considered. The FE analysis results are summarised with the maximum load and the Specific Energy Absorption (SEA) since they are the key factors in determining the crashworthiness of automotive structures. The results may also be able to indicate how to achieve lightweight structure of the automotive bumper system either directly or indirectly.

• 보건교육건강증진학회지
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• 제22권2호
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• pp.97-110
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• 2005

Objectives: Recent studies have shown that tailored messages for cancer screening to the beliefs and stage of cancer screening behavior of individual women increases the take-up probability. Many studies on cancer screening have used the Transtheoretical Model (TTM) to identify variables associated with cancer screening behavior. This study was carried out to identify the cognitive-behavioral factors associated with stomach cancer screening among women aged 40 years and over, and to develop and evaluate a tailored educational program for stomach cancer screening by stages of change. Methods: Building on the TTM constructs, we conducted a quasi-experimental study(N=283) to test the effectiveness of a tailored educational program for endoscopic stomach cancer screening. We carried out pre and post tests in the experimental group(N=162) and the control group(N=121), and the experimental group was subdivided into an on-line group(N=81) and an off-line group(N=81) by educational methodology using e-mail and the postal service. We used the chi-square test, trend test, and paired t-test to test the effectiveness of the program for stomach cancer using a tailored stage-matched messages. Results: To examine the effectiveness of the program for stomach cancer screening by the tailored stage-matched messages, the stage-matched materials were offered to the experimental group(N=162) four times for 4 weeks. The stage-matched materials consisted of the four types for stomach cancer. The tailored message was effective in changing the cognitive-behavioral factors, such as experience process, behavior process, con opinion for stomach cancer, self-efficacy, and the behavioral stages for stomach cancer screening. The stomach cancer screening adherence was higher for the stage-matched materials using postal mail than for those using e-mail. Conclusion: To improve the stomach cancer screening rate, the use of tailored messages for stomach cancer screening will be generated using an expert system. Therefore the implementation of tailored educational program will be supported a partnership between public and private health organizations and increasing awareness of the necessity of community-based interventions.

• Journal of Electrical Engineering and Technology
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• 제4권1호
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• pp.98-105
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• 2009

This paper presents the characteristics of soil ionization for different water contents, and the parameters associated with the dynamic properties of a simple model grounding system subject to lightning impulse currents. The laboratory experiments for this study were carried out based on factors affecting the soil resistivities. The soil resistivities are adjusted with water contents in the range from 2 to 8% by weight. A test cell with a spherical electrode buried in the middle of the hemispherical container was used. As a result, the electric field intensity $E_c$ initiating ionization is decreased with the reduction of soil resistivities. Also, as the water content increased, the pre-ionization resistance $R_1$ and the post-ionization resistance $R_2$ became lower with increasing current amplitude. The time-lag to ionization $t_1$ and the time-lag to the second current peak $t_2$ at high applied voltages were significantly shorter than those of low applied voltages. It was found that the soil ionization behaviors are highly dependent on the water content and the applied voltage amplitude.

• 한국농업기계학회:학술대회논문집
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• 한국농업기계학회 2000년도 THE THIRD INTERNATIONAL CONFERENCE ON AGRICULTURAL MACHINERY ENGINEERING. V.II
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• pp.139-145
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• 2000

The mechanism of the inner resistance in a rubber crawler system has been investigated to reduce the power requirement (Kitano et al. 1994). The rolling resistance of the track roller, which is one of the major inner resistances, was measured for seven different vertical loads. The rolling resistance changed periodically and could be classified into three types. In case of the vertical load less than 500N, the rolling resistance was almost constant. For the vertical load greater than 500N, the maximum value of the rolling resistance increased. Further more in case of the vertical load greater than 1200N, negative resistance appeared. Analytical simulation of the travel resistance based on experimental results and static equilibrium equations derived from three-dimension mechanical model for the rubber crawler system. It was found that the simulation method was carried out to evaluate the travel resistance occurred by the rolling resistance of the track roller. The rolling resistance for each track roller arrangement and effects of the lug phase in the right and left rubber crawler could be estimated quantitatively.

• Asian-Australasian Journal of Animal Sciences
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• 제28권5호
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• pp.703-715
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• 2015

One of the challenges to increase milk production in a large pasture-based herd with an automatic milking system (AMS) is to grow forages within a 1- km radius, as increases in walking distance increases milking interval and reduces yield. The main objective of this study was to explore sustainable forage option technologies that can supply high amount of grazeable forages for AMS herds using the Agricultural Production Systems Simulator (APSIM) model. Three different basic simulation scenarios (with irrigation) were carried out using forage crops (namely maize, soybean and sorghum) for the spring-summer period. Subsequent crops in the three scenarios were forage rape over-sown with ryegrass. Each individual simulation was run using actual climatic records for the period from 1900 to 2010. Simulated highest forage yields in maize, soybean and sorghum- (each followed by forage rape-ryegrass) based rotations were 28.2, 22.9, and 19.3 t dry matter/ha, respectively. The simulations suggested that the irrigation requirement could increase by up to 18%, 16%, and 17% respectively in those rotations in El-Nino years compared to neutral years. On the other hand, irrigation requirement could increase by up to 25%, 23%, and 32% in maize, soybean and sorghum based rotations in El-Nino years compared to La-Nina years. However, irrigation requirement could decrease by up to 8%, 7%, and 13% in maize, soybean and sorghum based rotations in La-Nina years compared to neutral years. The major implication of this study is that APSIM models have potentials in devising preferred forage options to maximise grazeable forage yield which may create the opportunity to grow more forage in small areas around the AMS which in turn will minimise walking distance and milking interval and thus increase milk production. Our analyses also suggest that simulation analysis may provide decision support during climatic uncertainty.

• Korean Journal of Radiology
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• 제24권8호
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• pp.772-783
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• 2023

Objective: Imaging-based survival stratification of patients with gliomas is important for their management, and the 2021 WHO classification system must be clinically tested. The aim of this study was to compare integrative imaging- and pathology-based methods for survival stratification of patients with diffuse glioma. Materials and Methods: This study included diffuse glioma cases from The Cancer Genome Atlas (training set: 141 patients) and Asan Medical Center (validation set: 131 patients). Two neuroradiologists analyzed presurgical CT and MRI to assign gliomas to five imaging-based risk subgroups (1 to 5) according to well-known imaging phenotypes (e.g., T2/FLAIR mismatch) and recategorized them into three imaging-based risk groups, according to the 2021 WHO classification: group 1 (corresponding to risk subgroup 1, indicating oligodendroglioma, isocitrate dehydrogenase [IDH]-mutant, and 1p19q-codeleted), group 2 (risk subgroups 2 and 3, indicating astrocytoma, IDH-mutant), and group 3 (risk subgroups 4 and 5, indicating glioblastoma, IDHwt). The progression-free survival (PFS) and overall survival (OS) were estimated for each imaging risk group, subgroup, and pathological diagnosis. Time-dependent area-under-the receiver operating characteristic analysis (AUC) was used to compare the performance between imaging-based and pathology-based survival model. Results: Both OS and PFS were stratified according to the five imaging-based risk subgroups (P < 0.001) and three imaging-based risk groups (P < 0.001). The three imaging-based groups showed high performance in predicting PFS at one-year (AUC, 0.787) and five-years (AUC, 0.823), which was similar to that of the pathology-based prediction of PFS (AUC of 0.785 and 0.837). Combined with clinical predictors, the performance of the imaging-based survival model for 1- and 3-year PFS (AUC 0.813 and 0.921) was similar to that of the pathology-based survival model (AUC 0.839 and 0.889). Conclusion: Imaging-based survival stratification according to the 2021 WHO classification demonstrated a performance similar to that of pathology-based survival stratification, especially in predicting PFS.

• Journal of Power Electronics
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• 제16권1호
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• pp.351-361
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• 2016

Power quality is a critical issue in distribution systems, where a dynamic voltage restorer (DVR) is commonly used to mitigate the voltage disturbances for loads. This paper deals with a nonlinear control for the three-phase four-wire (3P-4W) DVR under a grid voltage unbalance and nonlinear loads in the distribution system, where a novel control scheme based on the feedback linearization technique is proposed. Through feedback linearization, a nonlinear model of a DVR with a PWM voltage-source inverter (VSI) and LC filters is linearized. Then, the controller design of the linearized model is performed by applying the linear control theory, where the load voltages are kept constant by controlling the d-q-0 axis components of the DVR output voltages. To keep the load voltage unchanged, an in-phase compensation strategy is employed, where the load voltages are recovered to be the same as the previous voltage without a change in the magnitude. With this strategy, the performance of the DVR becomes faster and more stable even under unbalanced source voltages and nonlinear loads. The validity of the proposed control strategy has been verified by simulation and experimental results.

• 한국유체기계학회 논문집
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• 제17권5호
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• pp.43-53
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• 2014

This paper presents a the study on air curtain system of top and bottom bi-directional jet air discharge for blocking the spread of smoke in case of tunnel fire. The five kinds different air curtains of A, B, C, D, and E of models for various performance tested after manufactured. A results of the various performance test obtained the best efficiency from E model air curtain. And optimize the injection angle of the air curtain nozzle through the three-dimensional computational fluid dynamics (CFD) analysis and analyzed the effects of external pressure of tunnel. and also single factor design have been applied. At present, our attention is focused on the velocity distribution(flow width and flow position) of 1.5m on the ground in tunnel. Also, analyzed the influence of draft in the tunnel. Detailed effects of discharge angle of air curtain and velocity at nozzle exit are discussed.