• Asian Pacific Journal of Cancer Prevention
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• v.16 no.7
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• pp.2883-2887
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• 2015

Background: The calcium-binding S100A4 protein is involved in epithelial to mesenchymal transition, oncogenic transformation, angiogenesis, cytoskeletal integrity, mobility and metastasis of cancer cells. This study aimed to clarify the roles of S100A4 in genesis and progression of glioma. Materials and Methods: S100A4 expression was examined by real-time RT-CPR and Western blot in glioma and paired normal brain tissue (n=69), and compared with clinicopathological parameters of tumors. In addition, glioma U251 cells transfected with an S100A4-expressing plasmid were examined for proliferation by MTT, apoptosis by Annexin V-FITC, and migration and invasion with Transwell chambers. Results: Increased S100A4 mRNA expression was found in gliomas, compared with paired non-tumor tissue (p<0.001). Gradual elevation of overexpression of S100A4 was observed with increasing glioma grade (p<0.001). Astrocytoma showed lower S100A4 mRNA expression than oligodendrogliomas, with glioblastomas having highest values (p<0.001). Similar results were obtained for S100A4 protein, a positive link being found between mRNA and protein expression in gliomas (p<0.001). There was higher growth, lower apoptosis, stronger migration and invasion of S100A4 transfectants than control and mock transfected cells (p<0.001). Conclusions: These findings indicate that up-regulated S100A4 expression is positively linked to pathogenesis, progression and histogenesis of glioma by modulating proliferation, apoptosis, migration and invasion.

• Journal of the Institute of Electronics and Information Engineers
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• v.50 no.7
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• pp.191-201
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• 2013

In this paper, we propose a location based multicast routing protocol, called Geomulticast, in mobile ad-hoc wireless networks. The main features and contributions of the proposed geomulticast are as follows. First, support data transmission to only the specific mobile nodes within a target area. Second, establish stable routing route by using mobility information of nodes. Third, reduce control overhead, power for construction of routing route by using geomulticast guided line information. Fourth, present a theoretical model for establishing stable route. The performance evaluation of the proposed geomulticast is executed by using OPNET simulation and theoretical analysis, and the results of simulation and theoretical analysis have similar patterns. And we can see that data packets are efficiently transmitted to specific user groups within a specific area.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.29 no.12A
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• pp.1380-1386
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• 2004

Future communication networks would consist of wired and wireless access networks where there would be various types of traffic services. To meet the QoS requirements of those various traffic services simultaneously, new QoS control schemes are required. Since they are simple to deploy, cheep to manage, and easy to support subscriber mobility, wireless access networks are considered here. In this paper, a wireless joint buffer management and scheduling (W-JoBS) scheme, which is a modified version of the original JoBS algorithm at error-prone wireless access networks, is proposed. W-JoBS scheme is for providing service fairness among traffic classes with service compensation and channel-state dependent packet scheduling schemes. With computer simulation, this proposed W-JoBS scheme is evaluated and the performance of W-JoBS is compared with that of the original JoBS.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.33 no.4A
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• pp.377-386
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• 2008

In this paper, a new handover management scheme has been proposed to reduce handover latency and to support fast handover without packet losses, so that it may be applicable to the wireless mobile Internet system such as IPv6-based WiBro system. To minimize the handover latency in processing of movement detection, we propose the handover management scheme which simplifies the handover message exchanging procedure between mobile subscriber station (MSS) and network by integrating layer 2 and layer 3 handovers efficiently based on the layer2 information. To reduce the processing delay from new care-of-address (NCoA) configuration during handover, we propose that NCoA is created, distributed and managed by new access control router (NACR). In addition, in order to minimize the packet transmission delay and eliminate the packet losses, the proposed scheme employs a crossover router (CR) which is upper network located over PACR and NACR and employs the packet buffering for MSS. The simulation study shows that the proposed scheme achieves loss-free packet delivery and low latency in the environment of narrow overlapped cell area or high velocity of the MSS, comparing the performance with the conventional schemes.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.25 no.7
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• pp.531-536
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• 2012

We herein present results of flat and uniform polymer-blended small molecular semiconductor thin films. Which were produced for organic thin film transistors (OTFTs), using a simple pre-metered horizontal dipping process. The organic semiconducting thin films were composed of 6,13-bis(triisopropylsilylethynyl)-pentacene (TIPS-PEN) composite blended with a polymer binder of poly(${\alpha}$-methylstyrene) (PaMS). We show that the pre-metered horizontal-dip-coating(H-dip-coating) process allowed the critical control of the thickness of the blended TIPS-PEN:PaMs thin film. The fabricated OTFTs using the TIPS-PEN:PaMs films exhibited maximum field-effect mobility of $0.22\;cm^2\;V^{-1}\;s^{-1}$. These results demonstrated that H-dip-coated TIPS-PEN:PaMS films show considerable promise for the production of reliable, reproducible, and high-performance OTFTs.

• Journal of the Institute of Electronics Engineers of Korea CI
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• v.48 no.6
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• pp.25-34
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• 2011

In this paper, In this paper, we propose a Cooperative Routing Protocol (CooRP) for supporting network convergence and transmission services efficiently in mobile ad-hoc wireless sensor networks with Rayleigh fading environments. The main contributions and features of this paper are as follows. First, the routing routes are decided on route stability based on entropy concepts using mobility of nodes within the direction guided line region to increase the operational lifetime of routes as well as reduce control overhead for route construction. Second, a cooperative data transmission strategy based on the constructed stable routing route is used to increase packet delivery ratio with advanced SNR. Third, a theoretical analysis for cooperative data transmission of the proposed CooRP with outage probability is presented. The performance evaluation of the proposed CooRP is performed via simulation using OPNET and analysis. The results of performance evaluation show that the proposed CooRP by using stable routing routes and cooperative transmission can increase packet delivery ratio efficiently.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.44 no.4
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• pp.40-48
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• 2007

MANET constructs a network that is free and independent between sensor nodes without infrastructure. Also, there are a lot of difficulties to manage data process, control etc.. back efficiently from change of topology by transfer of sensor node that compose network. Especially, because each sensor node must consider mobility certainly, problem about energy use happens. To solve these problem, mechanisms that compose cluster of cluster header and hierarchic structure between member were suggested. However, accompanies inefficient energy consumption because sensing power level of sensor node is fixed and brings energy imbalance of sensor network and shortening of survival time. In this paper, I suggested intelligent clustering mechanism for efficient energy management to solve these problem of existent Clustering mechanism. Proposed mechanism corresponds fast in network topology change by transfer of sensor node, and compares in existent mechanism in circumstance that require serial sensing and brings elevation survival time of sensor node.Please put the abstract of paper here.

• Journal of Dental Rehabilitation and Applied Science
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• v.26 no.1
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• pp.33-38
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• 2010

Maxillectomy is a treatment option for maxillary cancer, which leaves the patient with a palatal defect. It may cause problems with facial deformation, swallowing, mastication, and speech. These functional problems and changes in appearance may result in psychological problems. To control these deficits after maxillectomy, surgical reconstruction or prosthodontic treatment can be chosen as a treatment option. Obturator prosthesis has been used as a preferred method of rehabilitation for most maxillectomy patients. This case is a patient who was classified Aramany classification II hemi-maxillectomy patient with residual teeth from #11-25, whose teeth had substantial labioversion and clinically lengthened from alveolar bone involution, thus making it hard to select proper framework design and resist to the rotational dislodging force of the obturator. Therefore we selected swing-lock attachment design to remain pre-existing crown and bridges and obtain retention and stability of obturator. The swing-lock RPD is economical than the conventional RPD because we can remain pre-existing crown and bridges. And residual teeth which have mobility and poor prognosis can be successfully retained through properly designed swing-lock RPD as it is functioning as a removable splint on the teeth.

• Journal of the Korean Institute of Telematics and Electronics
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• v.26 no.6
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• pp.38-47
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• 1989

A purely analytical model for HEMT's based on a two dimensional charge control simul-ation[4] is proposed. In this model proper treatment of diffusion effect of electron transport along a 2-DEG (two dimensional electron gas) channel is perfoemed. This diffusion effect is shown to effectively increase the bulk mibility and threshold voltage of the I-V curves compared to the existing models. The channel thickness and gate capacitance are expressed as functions of gate voltages covering subthreshold characteristics of HEMT's analytically. By introducing the finite channel opening and an effiective channel-length modulation, the solpe of the saturation region of the I-V curves ws modeled. The smooth transition of the I-V curves at linear-to-saturation regions of the I-V curves was possible using the continuous Troffimenkoff-type of field dependent mobility. Furthermore, a correction factor f was introduced to account for the finite transition section forming between a GCA and a saturated section. This factor removes large discrepancies in the saturation region of the I-V curve predicted by existing l-dimensional models.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.43 no.9 s.351
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• pp.88-98
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• 2006

VANET has several different characteristics from MANET such as high mobility of nodes and frequent change of node density and network topology. Due to these characteristics, the network topology based protocol, often used in MANET, can not be applied to VANET. In this paper, we propose an emergency warning message broadcast protocol using range based relay node selecting algorithm which determines the minimal waiting time spent by a given node before rebroadcasting the received warning message. Because the time is randomly calculated based on the distance between sender node and receiver node, a node chosen as a relay node is assured to have a minimal waiting time, even though it is not located at the border of radio transmission range. The proposed emergency warning message broadcast protocol has low network traffic because it does not need to exchange control messages for message broadcasting. In addition, it can reduce End-to-End delay under circumstances of low node density and short transmission range in VANET.