• Title/Summary/Keyword: MoCA-22

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Factors Influencing on the Cognitive Function in Type 2 Diabetics (2형 당뇨병 환자의 인지 기능에 영향 미치는 인자)

  • Goh, Dong Hwan;Cheon, Jin Sook;Choi, Young Sik;Kim, Ho Chan;Oh, Byoung Hoon
    • Korean Journal of Psychosomatic Medicine
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    • v.26 no.1
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    • pp.59-67
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    • 2018
  • Objectives : The aims of this study were to know the frequency and the nature of cognitive dysfunction in type 2 diabetics, and to reveal influencing variables on it. Methods : From eighty type 2 diabetics (42 males and 38 females), demographic and clinical data were obtained by structured interviews. Cognitive functions were measured using the MMSE-K (Korean Version of the Mini-Mental State Examination) and the Korean Version of the Montreal Cognitive Assessment (MoCA-K) tests. Severity of depression was evaluated by the Korean Version of the Hamilton Depression Rating Scale (K-HDRS). Results : 1) Among eighty type 2 diabetics, 13.75% were below 24 on the MMSE-K, while 38.8% were below 22 on the MoCA-K. 2) The total scores and subtest scores of the MoCA-K including visuospatial/ executive, attention, language, delayed recall and orientation were significantly lower in type 2 diabetics with cognitive dysfunction (N=31) than those without cognitive dysfunction (N=49) (p<0.001, respectively). 3) There were significant difference between type 2 diabetics with and those without cognitive dysfunction in age, education, economic status, body mass index, duration of diabetes, total scores of the K-HDRS, the MMSE-K and the MoCA-K (p<0.05, respectively). 4) The total scores of the MoCA-K had significant correlation with age, education, body mass index, family history of diabetes, duration of diabetes, total scores of the K-HDRS (p<0.05, respectively). 5) The risks of cognitive dysfunction in type 2 diabetics were significantly influenced by sex, education, fasting plasma glucose and depression. Conclusions : The cognitive dysfunction in type 2 diabetics seemed to be related to multiple factors. Therefore, more comprehensive biopsychosocial approaches needed for diagnosis and management of type 2 diabetes.

Normative Data of the Yonsei Dual Task Cognitive Screening Test (Y-DuCog) for Korean Older Adults and Characteristics of Cognitive Function (국내 고령자의 Y-DuCog 표준치, 인지기능에 관한 연구)

  • Kwak, Hosoung
    • Journal of The Korean Society of Integrative Medicine
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    • v.8 no.4
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    • pp.59-66
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    • 2020
  • Purpose : This study aimed to present normative data for older Korean adults completing the Yonsei dual task cognitive screening test (Y-DuCog) and identify changes in cognitive function on the Montreal Cognitive Assessment - Korean (MoCA-K) with age. Methods : From May 2019 to August 2019, 195 healthy adults aged ≥60 years participated in this study. All participants completed the Y-DuCog to assess their dual-task performance and the MoCA-K to assess their cognitive function. Participants were divided into three groups based on their age: 60~69 years, 70~79 years, and ≥80 years. Results : The results of the Y-DuCog showed that dual-task performance time, effect, and correct response rate decreased significantly with age (p<.001). Scores from the three groups showed differences on all items (p<.001). Cognitive function on the MoCA-K also decreased significantly with age (mean score ± standard deviation [SD]; 27.33 ± 2.61 in subjects aged 60~69 years; 24.82 ± 3.20 in subjects aged 70~79 years; and 22.10 ± 4.91 in subjects aged ≥80 years; p<.001). Conclusions : Occupational therapists should be aware of the decline in cognitive function and dual-task performance time, effect, and correct response rate in older adults and consider interventions to treat this decline. Further studies are needed with larger groups of participants to examine factors, such as sex and education, that may impact dual-task performance and cognitive function.

Results of Korean Medicine Treatment in Community Dwelling Elderly with Mild Cognitive Impairment: Focusing on the Change in Cognitive Ability (지역사회 거주 경도인지장애 노인들을 대상으로 시행한 한의치료의 보고: 인지기능을 중심으로)

  • Kim, Yun-Na;Bae, Joon-Sang;Eom, Yoon-Ji;Lee, Kyung-Seok;Yoon, Hyun-Min;Cho, Seung-Hun
    • Journal of Oriental Neuropsychiatry
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    • v.30 no.3
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    • pp.185-198
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    • 2019
  • Objectives: The purpose of this study was to identify the effectiveness of Korean medicine treatment in mild cognitive impairment (MCI) among a group of community dwelling elderly. Methods: Two-hundred and twenty-nine elderly living in a community and diagnosed with MCI were recruited. Participants were evaluated with various instruments such as the Korean version of Mini-Mental State Examination for Dementia Screening (MMSE-DS) and the Korean version of Montreal Cognitive Assessment (MoCA-K). Korean medicine treatment consisted of herbal medicine, acupuncture, and pharmacoacupuncture. The change in cognitive ability was assessed by using the MMSE-DS and the MoCA-K. Data were analyzed by SPSS/WIN 22.0 using the paired t-test, and the ANOVA. Results: The MMSE-DS and the MoCA-K score generally increased after six months of Korean medicine treatment and the differences in both instruments were statistically significant. Additionally, some consecutive participants maintained long-term cognitive improvement. When analyzed specifically by herbal medicine group based on syndrome differentiation and pharmacoacupuncture group, most showed improvement in the MMSE-DS and the MoCA-K but not all data were statistically significant. The satisfaction score was mostly high and most participants were willing to re-participate in the program. Conclusions: Korean medicine treatment may contribute to the improvement and prevention of cognitive decline in the elderly. However, further systematic research based on large scale sample data and standardized protocols is needed to uplift the welfare and mental health of the elderly.

Mo,Cu-doped CeO2 as Anode Material of Solid Oxide Fuel Cells (SOFCs) using Syngas as Fuel

  • Diaz-Aburto, Isaac;Hidalgo, Jacqueline;Fuentes-Mendoza, Eliana;Gonzalez-Poggini, Sergio;Estay, Humberto;Colet-Lagrille, Melanie
    • Journal of Electrochemical Science and Technology
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    • v.12 no.2
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    • pp.246-256
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    • 2021
  • Mo,Cu-doped CeO2 (CMCuO) nanopowders were synthesized by the nitrate-fuel combustion method aiming to improve the electrical and electrochemical properties of its Mo-doped CeO2 (CMO) parent by the addition of copper. An electrical conductivity of ca. 1.22·10-2 S cm-1 was measured in air at 800℃ for CMCuO, which is nearly 10 times higher than that reported for CMO. This increase was associated with the inclusion of copper into the crystal lattice of ceria and the presence of Cu and Cu2O as secondary phases in the CMCuO structure, which also could explain the increase in the charge transfer activities of the CMCuO based anode for the hydrogen and carbon monoxide electro-oxidation processes compared to the CMO based anode. A maximum power density of ca. 120 mW cm-2 was measured using a CMCuO based anode in a solid oxide fuel cell (SOFC) with YSZ electrolyte and LSM-YSZ cathode operating at 800℃ with humidified syngas as fuel, which is comparable to the power output reported for other SOFCs with anodes containing copper. An increase in the area specific resistance of the SOFC was observed after ca. 10 hours of operation under cycling open circuit voltage and polarization conditions, which was attributed to the anode delamination caused by the reduction of the Cu2O secondary phase contained in its microstructure. Therefore, the addition of a more electroactive phase for hydrogen oxidation is suggested to confer long-term stability to the CMCuO based anode.

Association of Cognitive Dysfunction with Thyroid Autoantibody (갑상선 자가항체와 인지기능 저하의 연관성)

  • Han, Dong Kyun;Cheon, Jin Sook;Choi, Young Sik;Kim, Ho Chan;Oh, Byoung Hoon
    • Korean Journal of Psychosomatic Medicine
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    • v.24 no.2
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    • pp.227-235
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    • 2016
  • Objectives : The aims of this study were to know the frequency of cognitive dysfunction among patients with autoimmune thyroid disorders, and to reveal influencing factors on it, especially to clarify association with autoimmune thyroid antibodies. Methods : From sixty-five female patients with autoimmune thyroid disorders, demographic data were obtained by structured interview. Their cognitive funtions were measured using the MMSE-K and the MoCA-K tests. Depression was evaluated by the K-HDRS. Results : 1) Among patients with autoimmune thyroid disorders, 7.69% of them were below 24 on the MMSE-K, while 10.77% were below 22 on the MoCA-K. The frequency of cognitive deficit was not significantly different according to having positivity to antimicrosomal antibodies or not. 2) The antimicrosomal antibody-positive patients had significantly higher antithyroglobulin antibody titers, antimicrosomal antibody titers, and TSH concentration, while had significantly lower free T4 levels(p<0.05, respectively). 3) The total scores of the MMSE-K and the MoCA-K had significant correlation with age, marital status, antithyroglobulin antibody titers and K-HDRS(p<0.05, respectively). 4) The regression analysis revealed that variables such as age, education, autoimmune thyroid antibodies, thyroid function and depression did not influence on cognitive function of patients with autoimmune thyroid disorders. Conclusions : Our results could not support that cognitive function of patients with autoimmune thyroid disorders had correlation with autoimmune thyroid antibodies.

Mineral Contents in Bottled Natural Water and Estimation of Their Intake by Korean Adults (일부 무기질의 생수 중 함량 분석과 생수를 통한 섭취량 평가)

  • Kim, Moo-Kyung;Sim, Jin-Ah;Eom, Hee-Jung;Kim, Myung-Hee;Choi, Mi-Kyeong
    • Journal of the Korean Dietetic Association
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    • v.16 no.2
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    • pp.116-121
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    • 2010
  • Minerals play an important role in the body as essential nutrients. However, it is not easy to meet DRIs because food sources of minerals are limited. Recently, consumption of bottled natural water has been increasing in Korea due to water pollution and distrust of tap water. The present study was conducted to investigate mineral contents in bottled natural water and their intakes among Korean adults. We analyzed eight minerals in seven kinds of bottled natural water by ICP-spectrometry and conducted a survey on the intake status of water and bottled natural water with 400 Korean young adults. The mean contents of Ca, Mg, Fe, Zn, Cu, Mn, Se, and Mo in bottled natural water were 22.45${\pm}$22.48 mg/L, 10.59${\pm}$9.97 mg/L, 0.27${\pm}$0.18 ${\mu}g/L$, 2.06${\pm}$1.48 ${\mu}g/L$, 5.47${\pm}$0.70 ${\mu}g/L$, 1.43${\pm}$0.37 ${\mu}g/L$, 1.90${\pm}$0.96 ${\mu}g/L$, and 3.34${\pm}$0.79 ${\mu}g/L$, respectively. The mean age, height, weight, and BMI were 22.76 years, 174.94 cm, 68.64 kg, and 22.41 $kg/m^2$ for males (n=150) and 21.25 years, 162.04 cm, 51.05 kg, and 19.46 $kg/m^2$ for females (n=250), respectively. The respective daily intakes of total water and bottled natural water as water itself were 670.30 ml and 212.20 ml for males and 488.04 ml and 132.72 ml for females. The daily intakes of Ca, Mg, Fe, Zn, Cu, Mn, Se, and Mo from bottled natural water were 4.76 mg, 2.25 mg, 0.06 ${\mu}g$, 0.44 ${\mu}g$, 1.16 ${\mu}g$, 0.30 ${\mu}g$, 0.40 ${\mu}g$, and 0.71 ${\mu}g$ for males and 2.98 ${\mu}g$, 1.41 mg, 0.04 ${\mu}g$, 0.27 ${\mu}g$,0.73 ${\mu}g$, 0.19 ${\mu}g$,0.25 ${\mu}g$, and 0.44 ${\mu}g$ for females, respectively. Overall, the contents of Ca, Mg, and Se in bottled natural water were relatively high and the daily intakes of these minerals were 0.4~1.0% of the DRIs.

Mo-Mn Metallizing on Sintered Alumina and It합s Bond Strength (소결 알루미나의 금속접합 및 접합강도에 관한 연구)

  • Lee, Joon;Kim, Young-Tai;Jang, Sung-Do;Son, Yong-Bae
    • Journal of the Korean Ceramic Society
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    • v.22 no.6
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    • pp.58-70
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    • 1985
  • The bond strength of metal to ceramic sealing in Mo-Mn metallizing was investigated by examining the effects of flux composition in alumina ceramics particle size of molybdenum metal powder wet hydrogen atmosphere and temperature in metallizing. The maximum bond strength was obtained when the glass phase filled almost all the microstructural cavities around the interfacial area with few micropores. Such a favorable microstrcutre waas formed and maximum bond strength was observed between 130$0^{\circ}C$. Also the metal to ceramic bond strength was increased using finer molybdenum metal powder than coarse powder. When content of $SiO_2$ in the flux of alumina ceramics was constant metal to ceramic bond strength was improved with increasing the ratio of CaO to MgO in the flux.

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Comparison study of the wear metal analysis in oil sample by portable and bench-top XRF (휴대용 및 Bench-Top X-선 형광 분석기를 이용한 오일 시료 중 마찰 금속의 비교 분석)

  • Choi, Soo-Jung;Kim, Chong-Hyeak;Lee, Sueg-Geun;Kim, Dong-Pyo
    • Analytical Science and Technology
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    • v.22 no.5
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    • pp.422-431
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    • 2009
  • The analytical results of wear metals such as Na, Mg, Al, Si, P, Ca, Ti, V, Cr, Mn, Fe, Ni, Cu, Zn, Mo, Ag, Cd, Sn, Ba, Pb in oil samples are compared by portable and bench-top XRF methods as a basic study for the development of portable X-ray fluorescence spectrometer. The instrumental parameters such as measurement time of portable and bench-top XRF were optimized using certified reference materials of hydrocarbon oil with 20 wear metals in concentration range from 10 to 900 mg/kg. The analytical results of 20 wear metals in certified reference materials and new/used engine oil samples were compared by empirical and fundamental parameter methods.

SHRIMP U-Pb Age Determination for the Gneissic Country Rocks Around the Hongcheon Iron-REE Depsosit (홍천 철-희토류 광상의 편마암질 주변암에 대한 SHRIMP U-Pb 연령측정)

  • Kim, Myoung-Jung;Park, Kye-Hun;Koh, Sang Mo;Yi, Keewook
    • The Journal of the Petrological Society of Korea
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    • v.22 no.4
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    • pp.299-305
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    • 2013
  • It is well known that the Hongcheon iron-rare earth deposit is composed of carbonatite-phoscorite complex. We conducted zircon U-Pb age determination for the gneissic country rocks of this deposit. As the result we obtained ca. 1830 Ma, which is somewhat younger than igneous and metamorphic ages of ca. 1870 Ma generally reported from the Gyeonggi massif, suggesting further investigations for the timing and evolution of the Paleoproterozoic activities of the Gyeonggi massif.

Processing of Leaflike and Powder Tea Using Sea Tangle (다시마를 이용한 엽상 및 분말차 개발)

  • 배태진;곽지만;김해섭;김귀식
    • Journal of Life Science
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    • v.12 no.1
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    • pp.16-25
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    • 2002
  • To summarize our interpretation of the results, we can explain shown below. Optimum con dictions in order to soften of sea tangle leafs were treated in the solutions of 0.05% $CH_3$COOH at 9$0^{\circ}C$ for 0.5 hour, 0.2% $K_2$HPO$_4$at 10$0^{\circ}C$ for 0.5 hour and 0.3% NaHCO$_3$at 10$0^{\circ}C$ for 0.5 hour. After sea tangle leafs were treated in the solutions of 0.05% $CH_3$COOH at 9$0^{\circ}C$ for 0.5 hour and added 10% seasoning agent of 0.5% glutamic acid, 3% glycine, 5% sorbitol and 1.5% soy sauce. Contents of free amino acid in the leaflike tea were a large amount as alanine of 707.2 $\mu$mo1/100$m\ell$ and glutamic acid of 343.6 $\mu$mo1/100 $m\ell$. And contents of mineral were order Na of 49.38 ppm, Mg of 10.72 ppm, K of 10.56 ppm and Ca of 6.55 ppm. Powder tea was added 0.05% glutamic acid, 5% glycine, 5% glucose and 4% sodium chloride in sea tangle powder, and then pressure treatment at 11$0^{\circ}C$ for 1.5 hours. Contents of free amino acid in the powder tea were a large amount as glycine of 222.04 $\mu$mo1/100$m\ell$ and glutamic arid of 208.58 $\mu$mol/100$m\ell$. And contents of mineral were order Na of 104.24 ppm, Mg of 14.31 ppm, K of 9.68 ppm, Fe of 2.36 ppm, Ca of 2.00 ppm, Zn of 0.13 ppm, Cu of 0.10 ppm and Mn of 0.01 ppm.