• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.11 no.1
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• pp.21-27
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• 2008

Purpose: The aim of this survey was to analyze the choice of sedative drugs and their side effects during pediatric endoscopic sedation in Korea. We also evaluated doctors, caretakers and patient satisfaction with the procedures. Methods: Between June 2006 and July 2006, a 16-item survey regarding current sedation practices, during one month, was mailed to 28 hospitals in Korea. The results of the survey responses were then analyzed. Results: Endoscopy performed under conscious sedation was reported in 89.0% of the responders and endoscopy under general anesthesia in 0.9% of 465 endoscopic procedures. Endoscopy under conscious sedation was performed in 89.1% for upper gastrointestinal endoscopy (GFS) and 88.1% for lower GFS. Midazolam was used for conscious sedation during the endoscopy in 84.5% of cases and propofol was used in two cases (0.5%). In addition, a bezodiazepine/opioid combination was used iin 84.6% (44 cases) for lower GFS. Patients were monitored with pulse oxymetry, EKG (91.4%) as well as automatic BP (5.1%). Transient hypoxia was the only side effect noted and was treated with supplemental oxygen (4.6%). Flumazenil was used in 2.71% of cases. The choice of sedation was made by the endoscopist (84%). The satisfaction rate for endoscopists was 68%, and for the patients and caretakers was 84% (as reported by the endoscopists). Conclusion: Midazolam was used only for the upper GFS and benzodiazepine/opioid combination was used for the lower GFS in Korea. The rate of satisfaction was relatively high and there were no significant side effects noted during the endoscopy under conscious sedation.

• Journal of Korean Society of Environmental Engineers
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• v.33 no.3
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• pp.174-182
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• 2011

The present study evaluated the major lead sources in a steel metallurgy industrialized city by measuring lead isotopes/lead concentrations of ambient air and potential sources in an industrial area and residential areas according to relative distance. The quality control program obtained during the measurement procedure for lead isotopes and concentrations exhibited $0.5ng/m^3$ for method detection limit, more than 90% for recoveries of standard particulate matters, and lower than 0.2% for reproducibility errors of four lead isotopes ($^{204}Pb$, $^{206}Pb$, $^{207}Pb$, $^{208}Pb$). For all three lead isotope ratios ($^{206}Pb/^{204}Pb$, $^{207}Pb/^{206}Pb$, $^{208}Pb/^{206}Pb$), the ratios were obtained in the industrial area were closer to nearby residential area than those of a residential area far away from the industrial area, thereby suggesting that lead sources were more similar each other in the industrial and nearby residential area. Furthermore, for both summer and winter seasons ambient lead concentrations were more than four times higher in the industrial area than in the residential areas and in turn, they were higher in the nearby residential area compared with the far-away residential area. As a result, it was suggested that lead emitted from the industrial area would influence more the ambient lead in the nearby residential area than the far-away residential area. Both slag and traffic emissions are likely to be major lead sources in the industrial and nearby residential areas, since their three lead isotope ratios ($^{206}Pb/^{204}Pb$, $^{207}Pb/^{206}Pb$, $^{208}Pb/^{206}Pb$) were similar to the ratios obtained from ambient air of these two areas. In addition, the lead isotope ratios revealed different pattern between seasons, and the ambient lead concentrations were higher for winter than for summer.

• Journal of Korean Society of Environmental Engineers
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• v.39 no.8
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• pp.449-455
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• 2017

Process input data including material and energy, process output data including product, co-product and its environmental emissions of the reference and target processes were collected and analyzed to evaluate the process performance. Environmentally problematic input/environmental emissions of the manufacturing processes were identified using these data. Significant process inputs contributing to each of the environmental emissions were identified using multiple regression analysis between the process inputs and environmental emissions. Optimum combination of the end-of-pipe technologies for treating the environmental emissions considering economic aspects was made using the linear programming technique. The cement manufacturing processes in Korea and the EU producing same type of cement were chosen for the case study. Environmentally problematic input/environmental emissions of the domestic cement manufacturing processes include coal, dust, and $SO_x$. Multiple regression analysis among the process inputs and environmental emissions revealed that $CO_2$ emission was influenced most by coal, followed by the input raw materials and gypsum. $SO_x$ emission was influenced by coal, and dust emission by gypsum followed by raw material. Optimization of the end-of-pipe technologies treating dust showed that a combination of 100% of the electro precipitator and 2.4% of the fiber filter gives the lowest cost. The $SO_x$ case showed that a combination of 100% of the dry addition process and 25.88% of the wet scrubber gives the lowest cost. Salient feature of this research is that it proposed a method for identifying environmentally problematic input/environmental emissions of the manufacturing processes, in particular, cement manufacturing process. Another feature is that it showed a method for selecting the optimum combination of the end-of-pipe treatment technologies.

• Reproductive and Developmental Biology
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• v.36 no.3
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• pp.147-154
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• 2012

This study was designed to determine whether low-density lipoproteins (LDL) from egg yolk and taurine, hypotaurine and trehalose as antioxidant in extender improve the freezability and fertility of Korean Jeju Black Bull semen. The semen was cryopreserved with tris egg yolk extenders containing 7% glycerol and treated 4% LDL, 20 mM taurine, hypotaurine and trehalose. Frozen-thawed sperm were evaluated motility, viability, membrane, and acrosome integrity and sperm penetration ability. The results were compared to semen cryopreserved in tris egg yolk extender only as control. Frozen-thawed semen evaluation cleary indicated that the addition of LDL and LDL-antioxidants (taurine, hypotaurine and trehalose) combination were significantly improved (p<0.05) the viability (%; with staining test using eosin-Y) compared to control spermatozoa. Also, in membrane integrity (%; with supravital hypo-osmotic swelling test), not only LDL-antioxiants combination but also LDL were significantly increased (p<0.05) the swelled sperm using HOST compared to control. Sperm acrosome integrity state was classified by CTC (chlortetracycline) staining test. F pattern was significantly increased in LDL-antioxidant combination than control (p<0.05) and B pattern was not significantly differences among all treatments and control. However, AR pattern was significantly decreased in LDL-antioxidants combination than control (p<0.05). Pronucleus formation and sperm penetration index (SFI) were significantly increased in LDL and LDL-antioxidants combination than control (p<0.05). Especially, LDL-taurine significantly improved pronucleus fomation and SFI than LDL (p<0.05). It was concluded that LDL and LDL-antioxidants in extender improved the freezability and fertility of Korean Jeju Black bull spermatozoa.

• Journal of Korean Society of Environmental Engineers
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• v.33 no.9
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• pp.662-669
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• 2011

This study was conducted to biologically convert methane into methanol. Methane contained in biogas was bio-catalytically oxidized by methane monooxygenase (MMO) of methanotrophs, while methanol conversion was observed by inhibiting methanol dehydrogenase (MDH) using MDH activity inhibitors such as phosphate, NaCl, $NH_4Cl$, and EDTA. The degree of methane oxidation by methanotrophs was the most highly accomplished as 0.56 mmol for the condition at $35^{\circ}C$ and pH 7 under 0.4 (v/v%) of biogas ($CH_4$ 50%, $CO_2$ 50%) / Air ratio. By the inhibition of 40 mM of phosphate, 50 mM of NaCl, 40 mM of $NH_4Cl$ and $150{\mu}m$ of EDTA, methane oxidation rate could achieve more than 80% regardless of type of inhibitors. In the meantime, addition of 40 mM of phosphate, 100 mM of NaCl, 40 mM of $NH_4Cl$ and $50{\mu}m$ of EDTA each led to generating the highest amount of methanol, i.e, 0.71, 0.60, 0.66, and 0.66 mmol when 1.3, 0.67, 0.74, and 1.3 mmol of methane was each concurrently consumed. At that time, methanol conversion rate was 54.7, 89.9, 89.6, and 47.8% respectively, and maximum methanol production rate was $7.4{\mu}mol/mg{\cdot}h$. From this, it was decided that the methanol production could be maximized as 89.9% when MDH activity was specifically inhibited into the typical level of 35% for the inhibitor of concern.

• Korean Journal of Psychosomatic Medicine
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• v.25 no.2
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• pp.200-209
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• 2017

Objectives : The aim of this study was to analyze the relationship between depressive symptoms and sociodemographic factors associated with geriatric depression and insomnia and to examine the effects of these factors on depression. Methods : The severities of insomnia and depression in elderly aged 60 and older lived in Gwangmyeong city were evaluated and the related sociodemographic factors were investigated. From April 20, 2016 to December 1, 2016, Gwangmyeong city Mental Health Sevices consignment by department of psychiatry of a university-affiliated general hospital conducted surveys and interviews for total 837 elderly peoples lived in Gwangmyeong city by visiting welfare center and wards located in the city. Structured interviews were conducted using Insomnia Severity Index(ISI) and Short form-Geriatric Depression Scale(S-GDS) to examine the relationship between sociodemographic factors and the severities of insomnia and depression. Results : There were significant differences in S-GDS mean scores and age(below 70 years old, 70s, 80s, above 90 years old), type of health care(health insurance, medical aid), type of residency(own, not own) and marital status(single, married, divorced or widowed).There was a significant difference in education level, especially between not educated(and/or) elementary graduates and college graduate(F=3.227, p=0.012). Also, there were significant differences in age, type of health care, type of residency, number of household on divided S-GDS score above and below 10 scores(p<0.05). Insomnia measured by ISI was not significantly associated with sociodemographic factors(p>0.05), but was significantly associated with depressive symptoms(p<0.05). These findings suggest more severe insomnia symptom indicated the higher probability of depression and elderly with depressive symptoms had more severe insomnia. Conclusions : Geriatric depression has significant relationships with age, type of health care, type of residency, marital status, education and number of households. In addition, insomnia which is main symptom of depression in elderly, has important role in predicting the severity and diagnosis of depression.

• The Korean Journal of Pesticide Science
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• v.2 no.2
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• pp.102-107
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• 1998

The objective was to know if seed potato farmers in Kangwon alpine area control weeds effectively and use herbicides properly to control weeds. Seed potato farmers in Pyongcbang, Hoengsong, and Kangnung have noxious weeds, such as marsh pepper, lambsquarters, barnyard grass, mugwort, asiatic dayflower, hairy carbgrass, ladysthumb, common chickweed, field horsetail, and common purslain, in their farmyard. These are controlled by a combination of physical and chemical weed control methods. However, several weeds such as marsh pepper, field horsetail and, mugwort are poorly controlled by 2-fold amount of several herbicides, including paraquat, pendimethalin, and metribuzin (58% of the answered). Herbicides are not selected and used in a proper manner by seed potato farmers: most of farmers selected herbicides by their experience (51% of the answered) and dealers recommendation (34% of the answered), while only a few farmers of the answered took advantage of the Farmers Handbook for Herbicide Application. In addition, the selected herbicides, including non-registered ones such as paraquat and fluazifop-butyl, are applying three to five years in a succession. With these improper selection and usage of herbicides, sixty-seven percent of the answered farmers have experienced crop damage and seventy-five percent have poisoning. We conclude that a systemic educational program for the proper selection and use of herbicides is needed for seed potato farmers in Kangwon alpine area.

• The Korean Journal of Pesticide Science
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• v.3 no.3
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• pp.54-59
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• 1999

The objective was to know if corn growers at Hongchcel County, Kangwon-do, where corn is the major agricultural product, control weeds effectively and use herbicides properly to control weeds. Sixty-eight corn growers at Hongchon were participated in this survey. Corn growers have noxious weeds, such as hairy carbgrass, common purslane, lambsquarters, Asiatic dayflower, mugwort and barnyard grass in their corn fields. Forty-four percents of the answered corn growers control weeds by hand weeding, and the others by a combination of physical and chemical methods. Corn growers have a preference of paraquat and alachlor for a pre-emergence treatment (94% of the answered) and of paraquat, glufosinate, glyphosate and fluazifop-P-butyl for a post-emergence treatment (87% of the answered). Corn growers did not select and use herbicides in a proper manner. fifty-four percent of the answered corn fevers selected herbicides by their own experience and 18 percent by neighbors recommendation. Herbicides were not selected and used in a proper manner by corn growers: 54 percent of the answered selected herbicides by the experience of growers and 18 percent by the recommendation of neighbors. In addition, a half of the answered applied over two-fold higher amounts of herbicides than the recommended rate. With these improper- selection and use of herbicides, 37 percent of the answered have experienced the crop damage and 42 percent the herbicide poisoning. We conclude that the development of the educational program for the proper selection and use of herbicides is needed for corn growers in Kangwon-do.

• Journal of Nutrition and Health
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• v.39 no.7
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• pp.624-640
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• 2006

Dialysis patients are at risk of malnutrition not only because of losses of nutrients during peritoneal dialysis but also because of anorexia that results in inadequate nutrient intakes. The aim of this study was to estimate the nutritional status of 154 patients receiving continuous ambulatory peritoneal dialysis (CAPD), especially focused on protein-energy malnutrition and vitamin and mineral status. The mean age of the subjects was $5.12\;{\pm}\;12.4\;y$ with educational years of $12.3\;{\pm}\;0.4\;y$ for male and $9.6\;{\pm}\;0.4\;y$ for female. The mean duration of dialysis was $22.7\;{\pm}\;21.7\;mo$. The causes of renal failure included diabetes (32.7), chronic glomerulonephritis (15.0%), and hypertension (8.5%). The main complications associated with chronic renal failure were hypertension (86.1%), diabetes (35.4%) and liver disease (9.0%). The mean daily energy intake was $1216.8\;{\pm}\;457.3\;kcal$ and increased to $1509.2\;{\pm}\;457.2\;kcal$ when added with the energy from dextrose in dialysate. The latter was still much lower than estimated energy requirement but energy intake per kg of body weight (28.1 kcal/1 g) was within the range of that recommended for CAPD patients' diet therapy (25 - 30 kcal/kg). The average daily intake of protein was $49.2\;{\pm}\;25.1\;g$ with 37.6% of the patients showing their intakes less than Estimated Average Requirement. The average protein intake per kg of weight was 0.9 g/kg, which is less than that recommended for CAPD patients (1.2-1.5g/kg) with mean serum albumin level $3.2\;{\pm}\;0.5\;g/dl$. The proportion of the patients with dietary calcium intake less than EAR was 90.9%, but when added with supplementary calcium (phosphorus binder), most patients showed their total calcium intake between EAR and UL. Fifty percent of the patients were observed with dietary iron intake less than EAR, however most patients revealed their total iron intake with supplementation above UL. The addition of folic acid with supplementation increased mean total folic intake to $1126.0\;{\pm}\;152.4\;{\mu}g$ and ninety eight percent of the subjects showed their total folic acid intake above UL. The prevalence of anemia was 83.1 % assessed with hemoglobin level, even with high intakes of iron with supplementation. Thirty four percent of the patients showed their fasting blood glucose was not under control $(\geq\;126\;mg/dl)$ even with medication or insulin probably due to dextrose from dialysate. The mean blood lipid levels were within the reference levels of hyperlipidemia, but with 72.1 % of the patients showing lower HDL-C. In conclusion, Fairly large proportion of the patients were observed with protein malnutrition with low intake of protein and serum albumin level. Few patients showed their vitamins and minerals intake less than EAR with supplementation. For iron and folic acid, their intakes were increased to above UL for large proportion of he patients. However, more than eighty percent of the patients were still anemic associated with decreased renal function. The serum blood glucose and lipid level were not under control for some patients with medication. It seems that supplementation and medications that patients are taking should be considered for dietary consulting of CAPD patients.

• Journal of Soil and Groundwater Environment
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• v.13 no.4
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• pp.8-21
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• 2008

A series of three-dimensional numerical simulations using a hydrodynamic dispersion numerical model is performed to analyze quantitatively impacts of layered heterogeneity of geologic media and groundwater pumping schemes on groundwater flow and salt transport in coastal aquifer systems. A two-layer heterogeneous coastal aquifer system composed of a lower sand layer (aquifer) and an upper clay layer (aquitard) and a corresponding single-layer homogeneous coastal aquifer system composed of an equivalent lumped material are simulated to evaluate impacts of layered heterogeneity on seawater intrusion. In addition, a continuous groundwater pumping scheme and two different periodical groundwater pumping schemes, which withdraw the same amount of groundwater during the total simulation time, are applied to the above two coastal aquifer systems to evaluate impacts of groundwater pumping schemes on seawater intrusion. The results of the numerical simulations show that the periodical groundwater pumping schemes have more significant adverse influences on groundwater flow and salt transport not only in the lower sand layer but also in the upper clay layer, and groundwater salinization becomes more intensified spatially and temporally as the pumping intensity is higher under the periodical groundwater pumping schemes. These imply that the continuous groundwater pumping scheme may be more suitable to minimize groundwater salinization due to seawater intrusion. The results of the numerical simulations also show that groundwater salinization in the upper clay layer occurs significantly different from that in the lower sand layer under the periodical groundwater pumping schemes. Such differences in groundwater salinization between the two adjacent layers may result from layered heterogeneity of the layered coastal aquifer system.