• 대한한방내과학회지
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• 제40권3호
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• pp.557-565
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• 2019

Objectives: This study investigated the effect of local acupuncture point stimulation and the application of a topical herbal mixed heating cream in a chronic cough patient who had not responded to various medications for more than a few months. Methods: An 81 year-old female patient who was suspected to be suffered from Upper Airway Cough Syndrome (UACS) was examined. The patient was treated with local acupuncture point stimulation and the application of a topical herbal mixed heating cream. We used the Leicester Cough Questionnaire, Cough-Specific Quality-of-Life Questionnaire, and Verbal Numerical Rating Scale to assess the patient's respiratory symptoms. Results: Local acupuncture point stimulation and the application of a topical herbal mixed heating cream resulted in the improvement of cough symptoms. The quality of life due to the alleviation of symptoms also significantly improved. Adverse effects were not observed. Conclusions: This study suggests that local acupuncture point stimulation and the application of a topical herbal mixed heating cream may be an effective therapy for the treatment of chronic cough in patients with UACS.

• 한방안이비인후피부과학회지
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• 제34권4호
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• pp.171-180
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• 2021

Objectives: The purpose of this study is to report the clinical course of a patient with mixed hemorrhoids treated with Korean medicine alone. Methods: A patient visited for an mixed hemorrhoids was treated with Korean herbal medicine. The effects of the treatment were evaluated via photography of hemorrhoids and symptoms of pain, bleeding, prolapse, itching, discharge and Total Symptom Score(TSS). Results: After treatment, in photography before and after, the size of hemorrhoids was reduced and lost. Scores of Pain (4→0), bleeding (3→0), prolapse (3→2), itching (0→0), discharge (1→0) and TSS (11.5->3) were observed. Conclusion: In light of the reduced size of hemorrhoids and scores of symptoms, herbal medicine might be a possible treatment method on mixed hemorrhoids.

• 응용통계연구
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• 제30권3호
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• pp.377-390
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• 2017

설문조사를 실시할 때 응답자가 설문조사의 일부 문항에 대하여 응답하지 않는 경우 항목무응답이 발생한다. 무응답이 발생한 자료를 제외하고 완전하게 응답된 자료 만에 근거한 분석은 분석 결과에 편의가 발생할 수 있으므로, 이를 채워 넣어 완전한 형태의 자료로 분석하기 위해서 무응답 대체가 흔히 사용되고 있으며 여러 가지 무응답 대체 기법들을 비교하는 연구들도 많이 존재한다. 패널조사 연구는 연구 대상 패널에 대하여 정해진 시간에 따라 반복적으로 동일한 설문 문항에 대하여 응답을 조사하여 시간에 따른 변화를 살펴보는 조사 방법을 나타낸다. 패널조사 자료의 항목 무응답을 대체할 때 이전 시점의 응답 자료가 존재한다면 이를 포함하여 대체를 실시하는 것이 바람직한 것으로 여겨져 왔으나 이에 관한 직접적인 연구는 찾기 힘들다. 따라서 본 연구에서는 패널자료에서 이전 시점의 정보를 고려하지 않고 대체를 실시하는 방법과 이전 시점의 정보를 활용하여 대체하는 방법들 중에서 어느 대체 방법이 보다 적절한 대체를 제공하는지 살펴보았다. 특히 이전 시점의 응답 정보를 이용하는 방법인 비대체, 선형혼합모형을 이용한 대체와 선형혼합모형에 근거한 베이지안 대체 방법을 고려하였고, 이를 이전 시점의 정보를 고려하지 않는 대체 방법들 중 흔히 사용되는 평균대체, 핫덱대체 방법과 비교하였다. 모의실험 결과 선형혼합모형에 근거한 베이지 안 대체 방법이 다른 대체 방법에 비해 무응답 비율이 높아지더라도 편의도 작으며 평균에 관한 95% 신뢰구간의 포함률도 높게 나타나서 가장 좋은 대체 방법으로 확인되었다.

• 품질경영학회지
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• 제46권1호
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• pp.27-38
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• 2018

Purpose: A large number of attributes with mixed levels are often considered in the conjoint analysis. In the cases where attributes have two or three levels, we research on the efficient design of survey questionnaire to estimate all the main effect and two factor interaction effects with a reasonable size of it. Methods: To reduce the number of questions in a questionnaire, the balanced incomplete block mixed level factorial design with minimum aberration was proposed by Lim and Chung (2016). Based on the number of questions and that of the respondents in that design, D-optimality criterion is adopted to find efficient designs where the main effect and two factor interaction effects are estimated. Results: The list of the number of questions and that of the respondents in efficient designs for survey questionnaire are recommended based on the D-efficiency of each design and the proposed selection criteria for the number of both questions and the respondents. By analyzing all the respondents survey data generated by the simulation study, we find the proper model. Conclusion: The proposed methods of designing survey questionnaires seem to perform well in the sense that how often the proper model is found in a simulation study where all the respondents survey data are generated by the simulation model.

• Structural Engineering and Mechanics
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• 제75권5호
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• pp.633-642
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• 2020

Artificial neural networks (ANNs) are known as intelligent methods for modeling the behavior of physical phenomena because of it is a soft computing technique and takes data samples rather than entire data sets to arrive at solutions, which saves both time and money. ANN is successfully used in the civil engineering applications which are suitable examining the complicated relations between variables. Functionally graded materials (FGMs) are advanced composites that successfully used in various engineering design. The FGMs are nonhomogeneous materials and made of two different type of materials. In the present study, the bending analysis of functionally graded material (FGM) beams presents on theoretical based on combination of mixed-finite element method, Gâteaux differential and Timoshenko beam theory. The main idea in this study is to build a model using ANN with four parameters that are: Young's modulus ratio (E_t/E_b), a shear correction factor (k_s), power-law exponent (n) and length to thickness ratio (L/h). The output data is the maximum displacement (w). In the experiments: 252 different data are used. The proposed ANN model is evaluated by the correlation of the coefficient (R), MAE and MSE statistical methods. The ANN model is very good and the maximum displacement can be predicted in ANN without attempting any experiments.

• Communications for Statistical Applications and Methods
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• 제13권3호
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• pp.701-718
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• 2006

In cancer microarray experiments, the experimenter or patient which is nested in each experimenter often shows quite heterogeneous error variability, which should be estimated for identifying a source of variation. Our study describes a Bayesian method which utilizes clinical information for identifying a set of DE genes for the class of subtypes as well as assesses and examines the experimenter effect and patient effect which is nested in each experimenter as a source of variation. We propose a Bayesian multilevel mixed effect model based on analysis of covariance (ANACOVA). The Bayesian multilevel mixed effect model is a combination of the multilevel mixed effect model and the Bayesian hierarchical model, which provides a flexible way of defining a suitable correlation structure among genes.

• Journal of Mechanical Science and Technology
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• 제19권11호
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• pp.2016-2024
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• 2005

In this work, a mixed beam approach that combines both the stiffness and the flexibility methods has been performed to analyze the coupled composite blades with closed, two-cell cross-sections. The Reissner's semi-complementary energy functional is used to derive the beam force-displacement relations. Only the membrane part of the shell wall is taken into account to make the analysis simple and also to deliver a clear picture of the mixed method. All the cross section stiffness coefficients as well as the distribution of shear across the section are evaluated in a closed-form through the beam formulation. The theory is validated against experimental test data, detailed finite element analysis results, and other analytical results for coupled composite blades with a two-cell airfoil section. Despite the simple kinematic model adopted in the theory, an accuracy comparable to that of two-dimensional finite element analysis has been obtained for cases considered in this study.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2000년도 제15차 학술회의논문집
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• pp.30-30
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• 2000

In the three axis control of satellite by using reaction wheel and gyro, a Gyro carries out measuring of the attitude angie and the attitude angular velocity. The Gyro is operated by the electronic part and the mechanic actuator. The digital part of the electronic part is consisted of the FPGA (Field Programmable Gate Array), which is one of the methods for designing VLSI (Very Large Scale Integrated Circuit), and the mechanic actuator processes the input/output data by the dynamic model. In the research of the mixed mode of Gyro, the simulation is accomplished by SABER of the mixed mode simulator and the results for the practical implementation of the satellite ACS (Attitude Control System) interfaced with the data processing are proposed.

• Communications for Statistical Applications and Methods
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• 제29권3호
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• pp.373-391
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• 2022

The distribution of observations in most econometric studies with spatial heterogeneity is skewed. Usually, a single transformation of the data is used to approximate normality and to model the transformed data with a normal assumption. This assumption is however not always appropriate due to the fact that panel data often exhibit non-normal characteristics. In this work, the normality assumption is relaxed in spatial mixed models, allowing for spatial heterogeneity. An inference procedure based on Bayesian mixed modeling is carried out with a multivariate skew-elliptical distribution, which includes the skew-t, skew-normal, student-t, and normal distributions as special cases. The methodology is illustrated through a simulation study and according to the empirical literature, we fit our models to non-life insurance consumption observed between 1998 and 2002 across a spatial panel of 103 Italian provinces in order to determine its determinants. Analyzing the posterior distribution of some parameters and comparing various model comparison criteria indicate the proposed model to be superior to conventional ones.

• 유체기계공업학회:학술대회논문집
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• 유체기계공업학회 2002년도 유체기계 연구개발 발표회 논문집
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• pp.47-53
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• 2002

The hydraulic design optimization and performance analysis of mixed-flow pumps for waterjet marine vehicle propulsion has been carried out using mean streamline analysis and three-dimensional computational fluid dynamics (CFD) code. In the present study the conceptual design optimization has been formulated with a non-linear objective function to minimize the fluid dynamic losses and then the commercial CFD code was incorporated to allow for detailed flow dynamic phenomena in the pump system. New designed mixed-flow model pump has been tested in the laboratory. Predicted performance curves by the CFD code agree very well with experimental data for a newly designed mixed-flow pump over the normal operating conditions. The design and prediction methods presented herein can be used efficiently as a unified hydraulic design process of mixed-flow pumps for waterjet marine vehicle propulsion.