• Title/Summary/Keyword: Mixed effects model

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An empirical bracketed duration relation for stable continental regions of North America

  • Lee, Jongwon;Green, Russell A.
    • Earthquakes and Structures
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    • v.3 no.1
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    • pp.1-15
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    • 2012
  • An empirical predictive relationship correlating bracketed duration to earthquake magnitude, site-to-source distance, and local site conditions (i.e. rock vs. stiff soil) for stable continental regions of North America is presented herein. The correlation was developed from data from 620 horizontal motions for central and eastern North America (CENA), consisting of 28 recorded motions and 592 scaled motions. The bracketed duration data was comprised of nonzero and zero durations. The non-linear mixed-effects regression technique was used to fit a predictive model to the nonzero duration data. To account for the zero duration data, logistic regression was conducted to model the probability of zero duration occurrences. Then, the probability models were applied as weighting functions to the NLME regression results. Comparing the bracketed durations for CENA motions with those from active shallow crustal regions (e.g. western North America: WNA), the motions in CENA have longer bracketed durations than those in the WNA. Especially for larger magnitudes at far distances, the bracketed durations in CENA tend to be significantly longer than those in WNA.

Dynamic response of post-tensioned rocking wall-moment frames under near-fault ground excitation

  • Feng, Ruoyu;Chen, Ying;Cui, Guozhi
    • Earthquakes and Structures
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    • v.15 no.3
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    • pp.243-251
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    • 2018
  • The dynamic responses of a rocking wall-moment frame (RWMF) with a post-tensioned cable are investigated. The nonlinear equations of motions are developed, which can be categorized as a single-degree-of-freedom (SDOF) model. The model is validated through comparison of the rocking response of the rigid rocking wall (RRW) and displacement of the moment frame (MF) against that obtained from Finite Element analysis when subjected ground motion excitation. A comprehensive parametric analysis is carried out to determine the seismic performance factors of the RWMF systems under near-fault trigonometric pulse excitation. The horizontal displacement of the RWMF system is compared with that of MF structures without RRW, revealing the damping effect of the RRW. Frame displacement spectra excited by trigonometric pulses and recorded earthquake ground motions are constructed. The effects of pulse type, mass ratio, frame stiffness, and wall slenderness variations on the displacement spectra are presented. The paper shows that the coupling with a RRW has mixed results on suppressing the maximum displacement response of the frame.

Modeling of the Parathyroid Hormone Response after Calcium Intake in Healthy Subjects

  • Ahn, Jae Eun;Jeon, Sangil;Lee, Jongtae;Han, Seunghoon;Yim, Dong-Seok
    • The Korean Journal of Physiology and Pharmacology
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    • v.18 no.3
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    • pp.217-223
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    • 2014
  • Plasma ionized calcium ($Ca^{2+}$) concentrations are tightly regulated in the body and maintained within a narrow range; thus it is challenging to quantify calcium absorption under normal physiologic conditions. This study aimed to develop a mechanistic model for the parathyroid hormone (PTH) response after calcium intake and indirectly compare the difference in oral calcium absorption from PTH responses. PTH and $Ca^{2+}$ concentrations were collected from 24 subjects from a clinical trial performed to evaluate the safety and calcium absorption of Geumjin Thermal Water in comparison with calcium carbonate tablets in healthy subjects. Indirect response models (NONMEM Ver. 7.2.0) were fitted to observed $Ca^{2+}$ and PTH data, respectively, in a manner that absorbed but unobserved $Ca^{2+}$ inhibits the secretion of PTH. Without notable changes in $Ca^{2+}$ levels, PTH responses were modeled and used as a marker for the extent of calcium absorption.

A STUDY ON DIMENSIONAL STABILITY OF THE RUBBER IMPRESSION MATERIALS FOLLOWING IMMERSION WITH CHEMICAL DISINFECTANTS (수종의 화학소독제에 침적시킨 고무인상체의 크기안정성에 관한 연구)

  • Kim, Hyung-Sik;Kim, Chang-Whe
    • The Journal of Korean Academy of Prosthodontics
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    • v.27 no.2
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    • pp.249-259
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    • 1989
  • Dental impression materials often become contaminated with patients' saliva and blood which creates the potential for cross-infection. It was the purpose of this study to investigate the effects of disinfection of three different rubber impression materials with four different disinfecting solutions. Polysulfide, vinyl polysiloxane and polyether impression materials were mixed according to the manufacturer's directions and samples were formed on a stainless steel model. On removal from the standard model, impressions were immersed in a disinfectant (acid-potentiated glutaraldehyde, phenollic compound, chlorine compound, iodophor) at room tempera tures for ten minutes. After disinfection, the distance between reference points(linear dimension) was measured using the non-contact automatic cordinate measuring projector(MZ-1, Nikon). Through statistical analyses on the data from this study,. the following conclusions were obtained. 1. Polysulfide, vinyl polysiloxane impressions were disinfected without dimensional change.(p>0.05) 2. Polyether impressions which were immersed in acid-potentiated glutaraldehyde were statistically different from control group.(p<0.05) But the amount of shrinkage(0.04%) would not be clinically significant. 3. By immersion of polysulfide, vinyl polysiloxane, polyether impressions in Banicide, Biocide, Multicide plus, sodium hypochlorite for ten minutes, clinically accurate impressions were obtained without dimensional change.

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The Use of Joint Hierarchical Generalized Linear Models: Application to Multivariate Longitudinal Data (결합 다단계 일반화 선형모형을 이용한 다변량 경시적 자료 분석)

  • Lee, Donghwan;Yoo, Jae Keun
    • The Korean Journal of Applied Statistics
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    • v.28 no.2
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    • pp.335-342
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    • 2015
  • Joint hierarchical generalized linear models proposed by Molas et al. (2013) extend the simple longitudinal model into multiple models fitted jointly. It can easily handle the correlation of multivariate longitudinal data. In this paper, we apply this method to analyze KoGES cohort dataset. Fixed unknown parameters, random effects and variance components are estimated based on a standard framework of h-likelihood theory. Furthermore, based on the conditional Akaike information criterion the correlated covariance structure of random-effect model is selected rather than an independent structure.

The Antecedents Of Brand Love Toward Natural Products: An Approach of S.O.R Theory

  • NGUYEN, Le Thai Hoa;NGUYEN, Hoang Anh
    • Asian Journal of Business Environment
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    • v.12 no.2
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    • pp.13-28
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    • 2022
  • Purpose: Natural products are becoming gradually popular because of their health - related benefits and consumers' environmental awareness. However, research in this field remains limited, the present study attempts to address this research gap by measuring the influencing levels of the antecedents on natural product brand love. Research design, data and methodology: The study employs S-O-R (Stimulus - Organism - Response) framework together with Innovation Resistance Theory and Dual-Factor Theory to propose the research model, in which health and environmental stimuli influence both of facilitators and inhibitors of internal states or organism, and then shape purchase intention and brand love as consumers' responses. The mixed research method is designed with the application of structural equation model (SEM) to analyze 530 consumers collected by convenience sampling. Results: The results revealed that two chosen stimuli, including health awareness and environmental concern were positively related to both facilitators (natural content and regional products) and inhibitors (image barrier and usage barrier) and these four factors were significantly associated to purchase intention and brand love. Furthermore, purchase intention played the mediating role on the relationship between the four organisms and brand love. Conclusions: The originality of this paper is extend S-O-R theory into natural product context with mediating effects in an emerging economy. The findings make theoretical contribution on consumer behavior and managerial implication.

Enhancing the ability of strain energy release rate criterion for fracture assessment of orthotropic materials under mixed-mode I/II loading considering the effect of crack tip damage zone

  • Khaji, Zahra;Fakoor, Mahdi
    • Steel and Composite Structures
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    • v.44 no.6
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    • pp.817-828
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    • 2022
  • In this study, considering dissipated energy in fracture process zone (FPZ), a novel criterion based on maximum strain energy release rate (SER) for orthotropic materials is presented. General case of in-plane loading for cracks along the fibers is assumed. According to the experimental observations, crack propagation is supposed along the fibers and the reinforcement isotropic solid (RIS) concept is employed as a superior model for orthotropic materials. SER in crack initiation and propagation phases is investigated. Elastic properties of FPZ are extracted as a function of undamaged matrix media and micro-crack density. This criterion meaningfully links between dissipated energy due to toughening mechanisms of FPZ and the macroscopic fracture by defining stress intensity factors of the damaged zone. These coefficients are used in equations of maximum SER criterion. The effect of crack initiation angle and the damaged zone is considered simultaneously in this criterion and mode II stress intensity factor is extracted in terms of stress intensity factors of damage zone and crack initiation angle. This criterion can evaluate the effects of FPZ on the fracture behavior of orthotropic material. Good agreement between extracted fracture limit curves (FLC's) and available experimental data proves the ability of the new proposed criterion.

An Empirical Analysis of the Bilateral Linkages between Foreign Direct Investment and Global Value Chains (해외직접투자와 글로벌 가치사슬의 양자간 연계성 실증 분석)

  • Hyun-Jung Choi;Hyun-Hoon Lee
    • Korea Trade Review
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    • v.47 no.4
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    • pp.233-254
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    • 2022
  • Although there is growing literature evidence of linkages between global value chains (GVCs) and foreign direct investment (FDI), the results are mixed and ambiguous by geographic dimension, time period and sectoral scope. Moreover, bilateral approaches on these connections have been rarely analyzed. In this context, we investigate the effect of bilateral greenfield FDI and cross-border M&A on GVC linkages between host countries and source countries. We match three-year averages of bilateral FDI and UNCTAD-Eora GVC value-added data from 2005 to 2019 between 37 OECD sources and 176 host countries (37 OECD versus 139 non-OECD countries). In the structural gravity model, the empirical specification includes bilateral and country-period fixed effects and uses a Poisson Pseudo-Maximum Likelihood (PPML) estimator. We find that greenfield and M&A FDI promote forward and backward GVC linkage for all sectors between OECD countries, whereas greenfield FDI promotes backward GVC linkage between OECD and non-OECD countries. In addition, the results indicate that the degree of influence of GVCs by FDI flows is greater for forward GVC than backward GVC among OECD countries.

The Injection Characteristics and Environmental Effects for Grouting Materials Based on Cement (시멘트계 주입재 종류별 주입 특성 및 환경적 영향 연구)

  • 천병식;이재영;서덕동
    • Journal of the Korean Geotechnical Society
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    • v.19 no.2
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    • pp.159-170
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    • 2003
  • In this study, the mixed design of grout with hish strength.high permeation.high durability and environmental stability as the state of the art in material field was performed. Also, the subjects of grouting, grouting effects for ground conditions, and environmental effects were analyzed. According to these results, the fundamental data will be suggested as a design of grouting in the field application. The physical, mechanical and chemical characteristics with particle shape of the grouts were analyzed. Then, the gel-time of grouts, which is essential for workability and permeation range, were controlled. Also, the laboratory model grouting tests were performed to find the characteristics of solidification, permeation and durability with grouts. The ordinary portland, slag and microcement which have been used in the construction field were evaluated fur the environmental effects. To find the leaching of $Cr^{6+}$characteristics in cement grouts, $Cr^{6+}$ leaching tests were performed for the raw materials. Also, the results of leaching test were shorn by surrounding environment. Then, the unconfined compression strength tests were performed with the homo-gel samples, and the amount of changed $Cr^{6+}$ was measured by curing solution.

Flow Characteristics Analysis of the Decontamination Device with Mixing and Diffusion Using Radio-Isotopes Tracer (방사성 동위원소를 이용한 제염제 혼합확산장치의 유동특성분석)

  • Oh, Daemin;Kang, Sungwon;Kim, Youngsug;Jung, Sunghee;Moon, Jinho;Park, Jangguen
    • Journal of Korean Society of Environmental Engineers
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    • v.39 no.5
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    • pp.282-287
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    • 2017
  • The purpose of this study was predicted the effects of mixing and diffusion due to the operation of the apparatus before the development of the mixed diffusion device for the decontamination absorbent to minimize the influence of contaminant inflow due to radiation accident. The tracer used for the flow characteristics was $^{68}Ga$, $^{99m}Tc$, which is a radioactive isotope, and 2 inch NaI radiation detector was used to detect it. The impeller of the decontamination mixed diffusion system applied to this study was made into three types and the mixing diffusion effect was compared. As a result of analyzing the flow characteristics of the radio-isotope with decontamination mixed diffusion device, mixing, diffusion and flow pattern were obtained. The radial mixing type impeller was able to diffuse to the water surface by the upflow flow, and the fin structure was adjusted for finding optimal conditions. The model 3 type consists of a fin guiding part and an auxiliary fin so that the diffusion speed is higher than that of other types of impellers. It also showed a short time to reach complete mixing.