Objectives: The aim of this study was to investigate levels of matrix metalloproteinase-8 (MMP-8) and substance P (SP) in root canal exudates during root canal treatment (RCT) of nonvital, painful teeth. Materials and Methods: Patients scheduled for nonsurgical RCT were prospectively selected; the study was performed after obtaining informed consent from the patients and was approved by the Institutional Review Board for Clinical Research of Gangnam Severance Hospital, Yonsei University (3-2008-0118). Canal exudates samples were collected using sterilized paper points from teeth scheduled for RCT across three different time periods. MMP-8 and SP levels were measured using enzyme-linked immunosorbent assay (ELISA). Data were analyzed using a mixed model analysis and the Pearson correlation analysis (p < 0.05). Results: MMP-8 and SP levels in GCF were decreased during RCT (p < 0.0001), and they showed a weak positive correlation to each other (p < 0.05). Patients' subjective pain levels and the response from percussion test were significantly related to SP level. Conclusions: This study demonstrated that periradicular inflammation endodontic origin can elevate SP and MMP-8 levels in root canal exudates. Interestingly, SP level of canal exudates showed a possibility of being used as an indicator of pain due to periapical pathosis.
Objective: This study was realized to evaluate the nutritional value of rice grains as a replacement for corn grains in the diet of growing Hanwoo steers. Methods: Two experimental diets were prepared: i) Corn total mixed ration (TMR) consisting of 20% corn grains and ii) Rice TMR consisting of 20% rice grains, in a dry matter (DM) basis. These treatments were used for in vitro rumen fermentation and in vivo growth trials. In the rumen fermentation experiment, the in vitro DM digestibility (IVDMD), in vitro crude protein digestibility (IVCPD), in vitro neutral detergent fiber digestibility, pH, ammonia nitrogen, and volatile fatty acids (VFA) were estimated at 48 h, and the gas production was measured at 3, 6, 12, 24, and 48 h. Twenty four growing Hanwoo steers (9 months old; body weight [BW]: 259±13 kg) were randomly divided into two treatment groups and the BW, dry matter intake (DMI), average daily gain (ADG), and feed conversion ratio (FCR) were measured. Results: The in vitro experiment showed that the IVDMD, IVCPD, and VFA production of the Rice TMR were higher than those of the Corn TMR (p<0.05). The growth trial showed no differences (p>0.05) in the final BW, ADG, DMI, and FCR between the two TMRs. Conclusion: The use of rice grains instead of corn grains did not exhibit any negative effects on the rumen fermentation or growth performance, thereby rice grains with a DM of less than 20% could be used as a starch source in the diet of growing steers.
The purpose of this study was to estimate primiparas' perceptions of their newborns and compare the changes of their perceptions related to feeding methods between the time I (post-partum 2nd-3rd day) and the time ll (post-partum 1st month). At the time Ⅰ, bottle-feeding method was 100% because mothers were separated from their babies. At the time Ⅱ, the methods of feeding were breast-feeding(29.7%), bottle-feeding(30.7%), mixed feeding(39.6%) .The subjects of this study were 101 primiparas. Data were collected between May to October 1994, using the Neonatal Perception Inventory devised by Broussard(1963) and added by Lee Ja Hyurg(1986) .The results of this study are as follows : 1. There was no significant difference of primiparas' perceptions of their newborns according to general characteristics. 1) The younger tended to estimate that newborns were less capable, and perceived that it would be more difficult for them to take care of babies. 2) There was no difference of mothers' perceptions of their babies according to having a job or not. 3) The lower educated tended to estimate that newborns were less capable, and perceived that it would be more difficult for them to take care of babies. 2. There were some changes of primiparas' perceptions of their babies related to feeding methods between the time I (post-partum 2nd-3rd day) and the time Ⅱ (post-partum 1st month).1) At the time Ⅰ, Breast-feeding mothers estimated that newborns were less capable, and perceived that it would be more difficult for them to take care of babies. But they showed positive perceptions at the time Ⅱ (P<0.05, p<0.1) 2) At the time Ⅰ, Bottle-feeding mothers tended to estimate that newborns were more capable, and perceived that it would be more easy for them to take care of babies. But they showed negative perceptions at the time Ⅱ 3) For breast-feeding mothers, positive-positive group was 53%, positive-negative group was 20%, negative-positive group was 10%, negative-negative group was 17%. For bottle-feeding mothers, positive-positive group was 55%, positive-negative group was 32%, negative-positive group was 10%, negative-negative group was 3%.
Kang, Min Woo;Oh, Sejin;Kim, Sung-Chul;Lee, Sang Soo
Korean Journal of Environmental Agriculture
/
v.38
no.1
/
pp.17-22
/
2019
BACKGROUND: Soil contamination of As is a very sensitive environmental issue due to its adverse impact on human health and different characteristics with other heavy metals. With public awareness of As poisoning, there has been growing interest in developing guideline and remediation technologies for As-contaminated soil. The objective of this research was to evaluate the effectiveness of stabilizing amendments and soil dressing methods on the mobility of As in the contaminated rice paddy soils nearby mining area. METHODS AND RESULTS: Different amendments were mixed with surface and subsurface contaminated soils at a ratio of 3% (w/w) and monitored for five months. Three different extractants including 0.01M $CaCl_2$, TCLP, and PBET were used to examine As bioavailability in the soil and the concentration of As in rice grain was also measured with an inductively coupled plasma (ICP) spectroscopy. The results showed that all amendment treatments decreased As concentration compared to the control. Especially, coal mine drainage sludge (CMDS) treatment showed the highest efficiency of decreasing As concentration in the soil and rice grain. The values of Pearson correlation (r) between As concentrations in the soil and rice grain were 0.782, 0.753, and 0.678 for $CaCl_2$, TCLP, and PBET methods, respectively. Especially, $CaCl_2$ method was highly correlated between As concentrations of the soil and soil solution (r=0.719), followed by TCLP (r=0.706), PBET (r=0.561) methods. CONCLUSION: Stabilizing amendments can effectively reduce available As concentration in the soils as well as soil solution, and thereby potentially mitigating risks of crop contamination by As.
One approach to improved image restoration methods has been the incorporation of additional source information via Gibbs priors that assume a source that is piecewise smooth. A natural Gibbs prior for expressing such constraints is an energy function defined on binary valued line processes as well as source intensities. However, the estimation of both continuous variables and binary variables is known to be a difficult problem. In this work, we consider the application of the deterministic annealing method. Unlike other methods, the deterministic annealing method offers a principled and efficient means of handling the problems associated with mixed continuous and binary variable objectives. The application of the deterministic annealing method results in a sequence of objective functions (defined only on the continuous variables) whose sequence of solutions approaches that of the original mixed variable objective function. The sequence is indexed by a control parameter (the temperature). The energy functions at high temperatures are smooth approximations of the energy functions at lower temperatures. Consequently, it is easier to minimize the energy functions at high temperatures and then track the minimum through the variation of the temperature. This is the essence of a continuation method. We show experimental results, which demonstrate the efficacy of the continuation method applied to a Bayesian restoration model.
Pharmaceuticals and personal care products (PPCPs) are emerging contaminants in the aquatic environment. Many pharmaceuticals are not completely removed during wastewater treatment, leading to their presence in wastewater treatment effluents, rivers, lakes, and ground water. Here, we developed analytical methods for monitoring ten pharmaceuticals from surface water by LC/ESI-MS/MS. For sample clean-up and extraction, MCX (mixed cation exchange) and HLB (hydrophilic-lipophilic balance) solid-phase extraction (SPE) cartridges were used. The limits of detection (LOD) in distilled water and the blank surface water were in the range of 0.006 - 0.65 and 1.66 - 45.05 pg/mL, respectively. The limits of quantitation (LOQ) for the distilled water and the blank surface water were in the range of 0.02 - 2.17 and 5.52 - 150.15 pg/mL, respectively. The absolute recoveries for fortified water samples were between 62.1% and 125.4%. Intra-day precision and accuracy for the blank surface water were 2.9% - 24.1% (R.S.D.) and -16.3% - 16.3% (bias), respectively. In surface wastewater near rivers, chlortetracycline and acetylsalicylic acid were detected frequently in the range of 0.017 - 5.404 and 0.029 - 0.269 ng/mL, respectively. Surface water near rivers had higher levels than surface water of domestic treatment plants.
Journal of the Korean Society of Clothing and Textiles
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v.42
no.5
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pp.753-768
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2018
This study reveals the aesthetic characteristics and formative characteristics of the converged images of romantic sportism by analyzing how sportism fashion and romantic images fuse together. As for research methods, this study examines the aesthetic and formative characteristics of sportism fashion and the aesthetic and formative characteristics of romantic styles after grasping the basic concept and background based on a literature study of romantic and sportism fashion. As for an empirical study, the styles of sportism fashion pictures of romantic images collected from 2010 S/S to 2016 S/S from www.vogue.com were analyzed. The study results showed that there are 4 aesthetic characteristics of romantic sportism in modern fashion that included 'non-oriented form visibility', 'non-boundary sensibility', 'multi-sense blend', and 'non-formal mixed usage'. The formative characteristics based on these aesthetic characteristics are also derived in accordance with design factors as well as analyzed through representative pictures.
Purpose: This article provides an update and overview of a nursing research program focused on understanding the pathophysiology and management of irritable bowel syndrome (IBS). Methods: This review includes English language papers from the United States, Europe, and Asia (e.g., South Korea) from 1999 to 2013. We addressed IBS as a health problem, emerging etiologies, diagnostic and treatment approaches and the importance of a biopsychosocial model. Results: IBS is a chronic, functional gastrointestinal disorder characterized by recurrent episodes of abdominal pain and alterations in bowel habit (diarrhea, constipation, mixed). It is a condition for which adults, particularly women ages 20-45, seek health care services in both the United States and South Korea. Clinically, nurses play key roles in symptom prevention and management including designing and implementing approaches to enhance the patients' self-management strategies. Multiple mechanisms are believed to participate in the development and maintenance of IBS symptoms including autonomic nervous system dysregulation, intestinal inflammation, intestinal dysbiosis, dietary intolerances, alterations in emotion regulation, heightened visceral pain sensitivity, hypothalamic-pituitary-adrenal dysregulation, and dysmotility. Because IBS tends to occur in families, genetic factors may also contribute to the pathophysiology. Patients with IBS often report a number of co-morbid disorders and/or symptoms including poor sleep. Conclusion: The key to planning effective management strategies is to understand the heterogeneity of this disorder. Interventions for IBS include non-pharmacological strategies such as cognitive behavior therapy, relaxation strategies, and exclusion diets.
Journal of Korean Institute of Industrial Engineers
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v.21
no.1
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pp.85-101
/
1995
Automated Guided Vehicles(AGVs) are widely used in computer integrated manufacturing(CIM) systems for material handling purposes. Although automated guided vehicles provide higher levels of flexibility and computer integrability, the installations are limited in number and one of the critical reasons lies in the complexity involved in the operation. The main objective of this research is to alleviate this problem by proposing efficient integrated operational control methods for AGV-based CIM systems. Particularly, this research is concerned with the mixed problem of dispatching automated guided vehicles and scheduling machines operation. The proposed dynamic heuristic algorithm uses various priority schemes and relevant information concerning the load of the system, the status of queues, and the position of AGVs in the scheduling process. The scheduling decision process is hierarchical in the sense that different decision criteria are applied sequentially to identify the most appropriate part to be served. This algorithm consists of two sections, the section of part selection by AGVs for the next service whenever an AGV completes the current assignment, and the section of part selection by machines for next service whenever a machine completes the current operation. The proposed algorithm has been compared with other scheduling schemes using the performance measure of mean flow-time and mean tardiness. Simulation results indicate that the proposed algorithm can reduce the mean flow-time and mean tardiness significantly.
Proceedings of the Korean Institute of Building Construction Conference
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2010.05a
/
pp.115-118
/
2010
The concept of construction information systems (IS) is very comprehensive and subjective. Acronyms in relation to the construction IS may include BIM, CIC, IT, nD-CAD, ERP, CALS, KM and so on. These terminologies are used in a somewhat mixed way causing possible misunderstandings in research and practice of construction information systems. Moreover, ever-changing construction business environment has widely affected the roles and methods of utilizing construction IS. Examples of these changes are dissemination of alternative project delivery systems, global standardization under highly competitive overseas market, and advancement of information and communication technologies. In this context, the purpose of this paper is to propose a high-level framework for information systems in the construction industry. Several different concepts in the area of construction IS were investigated first in order to identify the major variables of the framework. Trends of research and real-world implementations were then analyzed to support the rationale of the variables. Finally, a framework was proposed by re-arranging the relevant issues. Findings of this paper indicate that different acronyms commonly share many similar concepts in their definitions, however, in each acronym, the motivations and approaches to implementing construction IS are very different. Different approach can provide maximum effectiveness, while overlaps may happen causing practical inefficiency.
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