• Title/Summary/Keyword: Missouri Study

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Comparison of polymerase chain reaction for antigen receptor gene rearrangement and flow cytometric analysis for the diagnosis of canine lymphoma

  • Song, Ru-Hui;Yu, Do-Hyeon;Kim, Jun-Hwan;Lee, Hyun-Seok;Lee, Da-Mi;Park, Chul;Yu, Il-Jung;Park, Jin-Ho
    • Korean Journal of Veterinary Service
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    • v.34 no.3
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    • pp.265-271
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    • 2011
  • Lymphoma is the most common hematopoietic malignancy in dogs. Diagnosis of lymphoma is classically performed by morphological assessment and immunohistochemistry. But some cases in the early stage are difficult to distinguish and need more objective and accurate methods. So, Polymerase chain reaction (PCR) for antigen receptor rearrangements (PARR) and flow cytometric immunophenotype of lymphoma have been developed continuously. In this study, we performed these two methods to classify lymphoma type in 3 cases. According to PARR analysis, B cell origin lymphoma was diagnosed in two of three cases by testing PBMC and lymph node. All fine needle aspiration (FNA) samples of lymph nodes had high expression of CD21 on >88% of total cell population and PBMC samples also showed high expression of CD21 on >30% of total lymphocytes in those two cases, while the expression of CD3, CD4 and CD8 was absent. These results suggest that concurrent use of PARR and flow cytometric immunophenotype is more effective and valuable tool for the diagnosis and monitoring of canine lymphoma patients.

Environmental Restoration of Water System in Golf Courses (골프장내 수계의 환경친화적 복원)

  • Choi, Kyung-Young;Joo, Young-Kyoo;Kim, Su-Jung
    • Asian Journal of Turfgrass Science
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    • v.20 no.2
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    • pp.253-264
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    • 2006
  • It is a general trend that golf courses have been developed on mountain areas or in valleys due to economical or legal reasons in Korea. Therefore, most of golf courses have special landscape characteristics of brooks and ridge lines as well as peaks. Development of golf courses in the regions of intermediate valley significantly influences ecological factors such as biodiversity, hydrology, and biogeochemical cycles due to changes in original ecosystems of valleys, ridges, and peaks. This study developed a comprehensive framework to incorporate ecological principles and examples into the landscape planning and design process. The restoration system fur water environment may significantly minimize the ecological impacts from developing golf courses. Biotops and artificial damps have been applied to a golf course construction site in southern part of Korea, requiring a restoration of existing water ecosystem by the local EPA. The detailed drawings and water restoration plans were presented in this paper.

Crocin Improves Oxidative Stress by Potentiating Intrinsic Anti-Oxidant Defense Systems in Pancreatic Cells During Uncontrolled Hyperglycemia

  • Yaribeygi, Habib;Noroozadeh, Ali;Mohammadi, Mohammad Taghi;Johnston, Thomas P.;Sahebkar, Amirhossein
    • Journal of Pharmacopuncture
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    • v.22 no.2
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    • pp.83-89
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    • 2019
  • Introduction: Oxidative stress (OS) during uncontrolled hyperglycemia has a pivotal role in pancreatic dysfunction. Our study aimed to demonstrate that crocin can potentiate anti-oxidant defense systems of pancreatic cells to improve oxidative stress. Methods: Male Wistar rats were divided randomly into four groups: a normal group, a normal-treated group, a diabetic group and a diabetic-treated group (n = 6 rats per group). Diabetes was induced by a single dose of streptozotocin (45 mg/kg/IV). The treated groups received crocin daily for 8 weeks (40 mg/kg/IP). At the end of the experiment, rats were sacrificed and pancreas tissue was obtained. Subsequently, the concentrations of malondialdehyde (MDA), nitrate and glutathione as well as the enzymatic activities of catalase and superoxide dismutase (SOD) were determined in all animals. Data were analyzed by two-way ANOVA with appropriate post hoc testing and a probability value of P < 0.05 was considered to represent a statistically significant difference in mean values. Results: Uncontrolled hyperglycemia weakened the anti-oxidant system by decreasing SOD and catalase enzyme activity in pancreatic tissues and induced OS by increasing the MDA content in diabetic non-treated animals. Crocin potentiated the anti-oxidant defense system by increasing the activity of both SOD and catalase, and improved OS by diminishing MDA production in pancreatic cells of rats contained in the diabetic-treated group. Conclusion: Based on our results, it is concluded that uncontrolled hyperglycemia can weaken the anti-oxidant defense system and cause the development of OS. Also, crocin can improve OS in pancreatic cells by potentiating the anti-oxidant defense system.

Two Clinical Cases of Feline Hemoplasmosis in Korea

  • Kim, Young Ju;Bae, Hyeona;Shin, Sun Woo;Cho, ARom;Jeon, Yeseul;Hwang, Tae-Sung;Jung, Dong-In;Kim, Dae Young;Kang, Jun-Gu;Yu, DoHyeon
    • Parasites, Hosts and Diseases
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    • v.60 no.2
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    • pp.127-131
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    • 2022
  • Feline hemotropic mycoplasmosis (hemoplasmosis) is an infection of the red blood cells caused by the Mycoplasma haemofelis (Mhf), Candidatus Mycoplasma haemominutum (CMhm), and Candidatus Mycoplasma turicensis (CMt). The existence of Mhf, CMhm, and CMt has been demonstrated in feral cats in Korea using molecular methods, but no clinical cases have yet been reported. This study reports 2 clinical cases of hemotropic mycoplasmosis caused by CMhm and CMt in 2 anemic cats. The first case was a client-owned intact female domestic shorthair cat that presented with fever, pale mucous membranes, and normocytic normochromic non-regenerative anemia. Prior to referral, an immunosuppressive prednisolone dose was administered at the local veterinary clinic for 1 month. The cat was diagnosed with high-grade alimentary lymphoma. Organisms were found on the surface of the red blood cells on blood smear examination. The second case was of a rescued cat that presented with dehydration and fever. The cat had normocytic normochromic non-regenerative anemia. Necropsy revealed concurrent feline infectious peritonitis. Polymerase chain reaction assay targeting 16S rRNA revealed CMhm infection in case 1 and dual infection of CMhm and CMt in case 2. Normocytic normochromic non-regenerative anemia was observed in both cats before and during the management of the systemic inflammation. This is the first clinical case report in Korea to demonstrate CMhm and CMt infections in symptomatic cats.

Ensemble-based deep learning for autonomous bridge component and damage segmentation leveraging Nested Reg-UNet

  • Abhishek Subedi;Wen Tang;Tarutal Ghosh Mondal;Rih-Teng Wu;Mohammad R. Jahanshahi
    • Smart Structures and Systems
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    • v.31 no.4
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    • pp.335-349
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    • 2023
  • Bridges constantly undergo deterioration and damage, the most common ones being concrete damage and exposed rebar. Periodic inspection of bridges to identify damages can aid in their quick remediation. Likewise, identifying components can provide context for damage assessment and help gauge a bridge's state of interaction with its surroundings. Current inspection techniques rely on manual site visits, which can be time-consuming and costly. More recently, robotic inspection assisted by autonomous data analytics based on Computer Vision (CV) and Artificial Intelligence (AI) has been viewed as a suitable alternative to manual inspection because of its efficiency and accuracy. To aid research in this avenue, this study performs a comparative assessment of different architectures, loss functions, and ensembling strategies for the autonomous segmentation of bridge components and damages. The experiments lead to several interesting discoveries. Nested Reg-UNet architecture is found to outperform five other state-of-the-art architectures in both damage and component segmentation tasks. The architecture is built by combining a Nested UNet style dense configuration with a pretrained RegNet encoder. In terms of the mean Intersection over Union (mIoU) metric, the Nested Reg-UNet architecture provides an improvement of 2.86% on the damage segmentation task and 1.66% on the component segmentation task compared to the state-of-the-art UNet architecture. Furthermore, it is demonstrated that incorporating the Lovasz-Softmax loss function to counter class imbalance can boost performance by 3.44% in the component segmentation task over the most employed alternative, weighted Cross Entropy (wCE). Finally, weighted softmax ensembling is found to be quite effective when used synchronously with the Nested Reg-UNet architecture by providing mIoU improvement of 0.74% in the component segmentation task and 1.14% in the damage segmentation task over a single-architecture baseline. Overall, the best mIoU of 92.50% for the component segmentation task and 84.19% for the damage segmentation task validate the feasibility of these techniques for autonomous bridge component and damage segmentation using RGB images.

Cotyledon and Leaf Development Associated with Seeding Vigor of Six Forage Lerumes (여섯가지 두과목초의 유식물 활력과 관련된 자엽과 엽의 발달)

  • Hur, S.N.;Nelson, C.J.
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.15 no.1
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    • pp.19-23
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    • 1995
  • Cotyledon and leaf development of six important forage legums were compared to study their contribution to the seedling growth, Cotyledons of forage legumes expanded their size rapidly during one week maximum size was reached and entered senescence. Larger seeds produced greater colyledon area, and speed of colyledon expansion was closely associated with seedling growth. Earlier onset leaf production and earlier leaf development were major determinant factor initial seedling growth. Alfalfa and red clover which have larger seeds were good in seedling vigor with larger photosynthetic area. Alsike clover and white clover with small seeds showed also good seedling vigor, as they developed leaves early with relatively high photosynthetic rate. On the other hand, though lespedeza has heavy seeds, its seedling vigor was very poor with slow photosynthetic area development and low photosynthetic rate.

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Cost-effectiveness dynamics and vibration of soft magnetoelastic plate near rectangular current-carrying conductors

  • AliAsghar Moslemi Beirami;Vadim V. Ponkratov;Amir Ebrahim Akbari Baghal;Barno Abdullaeva;Mohammadali Nasrabadi
    • Structural Engineering and Mechanics
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    • v.88 no.2
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    • pp.159-168
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    • 2023
  • Cost-effective high precision hybrid elements are presented in a hierarchical form for dynamic analysis of plates. The costs associated with controlling the vibrations of ferromagnetic plates can be minimized by adequate determination of the amount of electric current and magnetic field. In the present study, the effect of magnetic field and electric current on nonlinear vibrations of ferromagnetic plates is investigated. The general form of Lorentz forces and Maxwell's equations have been considered for the first time to present new relationships for electromagnetic interaction forces with ferromagnetic plates. In order to derive the governing nonlinear differential equations, the theory of third-order shear deformations of three-dimensional plates has been applied along with the von Kármán large deformation strain-displacement relations. Afterward, the nonlinear equations are discretized using the Galerkin method, and the effect of various parameters is investigated. According to the results, electric current and magnetic field have different effects on the equivalent stiffness of ferromagnetic plates. As the electric current increases and the magnetic field decreases, the equivalent stiffness of the plate decreases. This is a phenomenon reported here for the first time. Furthermore, the magnetic field has a more significant effect on the steady-state deflection of the plate compared to the electric current. Increasing the magnetic field and electric current by 10-times results in a reduction of about 350% and an increase of 3.8% in the maximum steady-state deflection, respectively. Furthermore, the nonlinear frequency decreases as time passes, and these changes become more intense as the magnetic field increases.

Increasing trend of endoscopic drainage utilization for the management of pancreatic pseudocyst: insights from a nationwide database

  • Khaled Elfert;Salomon Chamay;Lamin Dos Santos;Mouhand Mohamed;Azizullah Beran;Fouad Jaber;Hazem Abosheaishaa;Suresh Nayudu;Sammy Ho
    • Clinical Endoscopy
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    • v.57 no.1
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    • pp.105-111
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    • 2024
  • Background/Aims: The pancreatic pseudocyst (PP) is a type of fluid collection that typically develops as a delayed complication of acute pancreatitis. Drainage is indicated for symptomatic patients and/or associated complications, such as infection and bleeding. Drainage modalities include percutaneous, endoscopic, laparoscopic, and open drainage. This study aimed to assess trends in the utilization of different drainage modalities for treating PP from 2016 to 2020. The trends in mortality, mean length of hospital stay, and mean hospitalization costs were also assessed. Methods: The National Inpatient Sample database was used to obtain data. The variables were generated using International Classification of Diseases-10 diagnostic and procedural codes. Results: Endoscopic drainage was the most commonly used drainage modality in 2018-2020, with an increasing trend over time (385 procedures in 2018 to 515 in 2020; p=0.003). This is associated with a decrease in the use of other drainage modalities. A decrease in the hospitalization cost for PP requiring drainage was also noted (29,318 United States dollar [USD] in 2016 to 18,087 USD in 2020, p<0.001). Conclusions: Endoscopic drainage is becoming the most commonly used modality for the treatment of PP in hospitals located in the US. This new trend is associated with decreasing hospitalization costs.

A Study on the Features of Entrepreneurship Education in Overseas Universities : Case of Five Universities in the United States (해외 대학의 창업교육 현황과 특징에 관한 연구 : 미국 5개 대학 사례를 중심으로)

  • Lee, Woo Jin;Kim, Yong Tae;HwangBo, Yun
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.8 no.1
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    • pp.99-110
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    • 2013
  • This study analyzed universities's entrepreneurship education curriculum and variety programs through visiting to five entrepreneurship centers. Through these analyzes, the study presents a basic frame work for prosperous entrepreneurship education in Korea. We have selected for visiting research universities in the middle east of the United states; University of Iowa, University of Missouri(Kansas City), Saint Louis University, University of Louisville and George Washington University. We visited entrepreneurship center of each university in order to have in-depth interview with professor who is responsible for building entrepreneurship curriculum and administrative director of entrepreneurial programs so that we research how university progresses entrepreneurship education at undergraduate level. The study, at the time of 61 universities selected for LINC project by the Korea Ministry of Education who expects Industrial-Academia cooperative effects just installed each entrepreneurship center, analyzed case study of operational practice and entrepreneurship education curriculum for the effective operation of entrepreneurship centers in universities. We believe that the study will be able to provide a richer and more accurate information and ideas since the all the analysis is based on the firsthand interview by visiting.

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The Relationship among Early Childhood Teachers' Perception on the Purpose of Multicultural Education, Multicultural Sensitivity and Multicultural Teaching Efficacy (유아교사의 다문화교육목표 관점 및 다문화감수성과 다문화교수효능감 간의 관계 분석)

  • Kim, Mi Jin;Kim, Hye Jin;Son, You Jin
    • Korean Journal of Childcare and Education
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    • v.11 no.3
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    • pp.63-83
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    • 2015
  • The purpose of this study was to examine the multicultural sensitivity of early childhood teachers, their perception on the purpose of multicultural education and any possible differences in those regards according to their background variables in an effort to determine the influence of the multicultural sensitivity of early childhood teachers and their perception on the purpose of multiculitural education on multicultural sensitivity, as the two variables were closely bound up with multicultural teaching efficacy. The subjects in this study were 283 selected early childhood teachers. The findings of the study were as follows: First, as for perception on the purpose of multicultural education, caring-centered perception was most common among the early childhood teachers, and their scores in multicultural sensitivity were a little above average. Second, there were significant differences among the teachers in multicultural sensitivity and perception on the purpose of multicultural education according to career, age and academic credential. Third, multicultural sensitivity and four perceptions on the purpose of multicultural education had a significant positive correlation with multicultural teaching efficacy. Multicultural sensitivity exerted the largest influence on multicultural teaching efficacy. Among the four perceptions of the purpose of multicultural education, caring-centered perception and social action-centered one turned out to have an impact on the subvariables of multicultural teaching efficacy. This study will provide basic information to prepare some solutions that enforce ealry childhood teachers' mulitucultutral education ability by improving their multicultural teaching efficacy.