• 제목/요약/키워드: Missing-step

검색결과 78건 처리시간 0.025초

범주형 자료에서 경험적 베이지안 오분류 분석 (Empirical Bayesian Misclassification Analysis on Categorical Data)

  • 임한승;홍종선;서문섭
    • 응용통계연구
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    • 제14권1호
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    • pp.39-57
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    • 2001
  • 범주형 자료에서 오분류는 자료를 수집하는 과정에서 발생될 수 있다. 오분류되어 있는 자료를 정확한 자료로 간주하여 분석한다면 추정결과에 편의가 발생하고 검정력이 약화되는 결과를 초래하게 되며, 정확하게 분류된 자료를 오분류하고 판단한다면 오분류의 수정을 위해 불필요한 비용과 시간을 낭비해야 할 것이다. 따라서 정확하게 분류된 표본인지 오분류된 표본인지를 판정하는 것은 자료를 분석하기 전에 이루어져야할 매우 중요한 과정이다. 본 논문은 I$\times$J 분할표로 주어지는 범주형 자료에서 두 변수 중 하나의 변수에서만 오분류가 발생되는 경우에 오분류 여부를 검정하기 위해서 오분류 가능성이 없는 변수에 대한 주변합은 고정시키고, 오분류 여부를 가능성이 있는 변수의 주변합을 Sebastiani와 Ramoni(1997)가 제안한 Bound와 외부정보로 표현되는 Collapse의 개념, 그리고 베이지안 방법을 확장하여 자료에 적합한 모형과 사전정보를 고려한 사전모수를 다양하게 설정하면서 재분류하는 연구를 하였다. 오분류에 대한 정보를 얻기 위해서 Tenenbein(1970)에 의해 연구된 이중추출법을 이용하여 오분류 검정을 위한 새로운 통계량을 제안하였으며, 제안된 오분류 검정통계량에 관한 분포를 다양한 모의실험을 통하여 연구하였다.

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단세포 RNA 시퀀싱 데이터를 위한 가중변수 스펙트럼 군집화 기법 (One-step spectral clustering of weighted variables on single-cell RNA-sequencing data)

  • 박민영;박세영
    • 응용통계연구
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    • 제33권4호
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    • pp.511-526
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    • 2020
  • 단세포 RNA 시퀀싱 데이터(single-cell RNA-sequencing data, 이하 단세포 RNA 데이터)는 세포 조직으로부터 추출한 각 단세포 별 유전자의 신호를 기록한 데이터로, 세포 간의 이질성을 파악하는 것을 주요 목적으로 한다. 그러나 단세포 RNA 데이터는 샘플링 및 기술적인 한계로 인해 결측비율이 높고, 노이즈가 크다. 이러한 이유 때문에 기존의 군집화 방법을 적용하는 데에 한계가 존재한다. 본 논문에서는 단세포 RNA 데이터 분석에서 모티브를 얻어 스펙트럼 군집화(spectral clustering) 기반의 방법을 제안한다. 특히 유사도 행렬(similarity matrix) 계산에서 유전자 별로 가중치를 부여하여 기존의 단세포 데이터 분석 방법과 차별화하였다. 제안하는 군집화 방법은 유전자별 가중치를 부여함과 동시에 세포를 군집화한다. 군집화는 반복 알고리즘을 통해 제안하는 비볼록식(non-convex optimization)을 풀어 진행한다. 또한 실데이터 적용과 시뮬레이션을 통해 제안하는 군집화 방법이 기존의 방법보다 군집을 잘 구분하는 것을 보인다.

단기순환림 생산을 위한 삽목 이식기 개발 (Development of Stem-cutting Transplanter for Short-term Rotation Coppice)

  • 김동화;김대철;김상헌;신범수
    • Journal of Biosystems Engineering
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    • 제35권1호
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    • pp.37-45
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    • 2010
  • Since SRC (Short-term Rotation Coppice) such as poplar and willow can be harvested in three years, they are known to be a potential forest biomass as fuel for a power plant. The production system including transplanting and harvesting is, however, necessary to be mechanized because such a biomass should be handled in a massive volumetric size. A pull-type stem-cutting transplanter was developed in the research as the first step to realize the production of SRC. A needle-like transplanting device pushes a stem-cutting into the prepared soil bed by a pneumatic cylinder, and another device firms soil around a stem-cutting transplanted. Since this is an intermittent operation, it was necessary to develop a zero horizontal velocity mechanism which enabled only the transplanting needle part to continue a zero horizontal movement relative to the ground during the transplanting operation even when the tractor kept moving forward. The 2-row transplanter can transplant stem-cuttings at the rate of 6.5 seconds per row without missing a single attempt. The planting depth and distance were well maintained and controlled. Their CVs were between 2.1~3.4% and 0.87~1.7% for the depth and the distance, respectively. Although, the transplanted stem-cuttings tended to lean outward from the back-view and forward from the side view, they were planted within the range of $3^{\circ}$ from the upright position.

국가재난의료체계에 대한 정책적 고찰 (A Strategic Study on National Disaster Medical System)

  • 백홍석
    • 한국응급구조학회지
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    • 제7권1호
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    • pp.235-246
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    • 2003
  • Due to major disasters Korea has been damaged, and they caused lots of casualties: for last ten years natural disasters caused 1288 deaths including missing people; human disasters including industrial disasters brought as many as 4,512.148 casual ties (126,372 deaths with 4,385,400 injuries); and they cost 44.1 trillion property damage. However, even though major disasters have brought about tremendous human loss and property damage, Koreas National Disaster Medical System to rescue casualties is insufficient, and it has not been activated. Fortunately, through major disaster management process, the National Disaster Management System has been developed, increasing its own efficiency, and resulting in to organize an Office of Firefighting and Prevention of Disasters under the central government. Considering the value of human lives, the disaster medical part, in the U.S.A. as well as in Korea, must have an independent organization in the government, not as one sector of the government department. It will have its own organizational structure, such as disaster planning, operation, and logistics, and interact with central and local government or between local government agencies. So each agency will cooperate and supply resources interchangeably. Also, with the system of disaster management and restoration, the disaster medical system must be advanced in keeping step. Its role must be extended due to the possibility of biological terror or SARS around the world, resulting in severe casualties. Korea has the Emergency Medical Service System based on the regulation of emergency medical care, yet it is a part of the National Disaster Management System. It must be managed independently apart from it. As we see the emergency medical technicians playing as the backbone in disaster medical care in the US, we should have legal foundations for Koreas emergency medical technicians, emergency medical providers, to participate in rescue operation actively. At the same time, we need to have a national register system to classify disaster medical resources, and a total plan to place resources according to the impact of disaster, and how to organize teams. We also need to draw up a scheme to activate civil disaster medical resources, as integrating public and private or voluntary organizations.

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한국(韓國)의 운기학(運氣學)에 관(關)한 연구(硏究) (A Study on Woongihak on Korea)

  • 홍진임;윤기령;윤창열
    • 대한한의학원전학회지
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    • 제30권4호
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    • pp.1-17
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    • 2017
  • Objective : Establishment and development of Woongihak on Korea requires detailed study into its contents including each period's Woongihak theory and clinical practices. Method : Woongihak is assumed to have been introduced during the Coreyo Dynasty. Then its development stage is divided into early, middle, later periods in Chosun dynasty, and the category further developed into the Japanese colonial period and then the post-liberation era. These periods were given respect to while medical textx and data related to Woongihak were collected and analyzed. Result & Conclusion : The general consensus is that Woongihak was introduced for the first time during the early period of Coryeo Dynasty, but there was no text around this era regarding Woongihak could have been found. Woongihak was found in Uibang-yuchwi, which entered Chosun Dynastyin early period and was published, where it annotated Sanghanjiggyeog, Saminbang, and eumjeungyaglye. Donguibogam, which was published during the middle period, introduced Woongi by hosting a sentence of Cheonjiungi, and Chochanggyeol was published during the late period and brought the level of Woongihak in Korea a step further. Lectures on Diagram of Woongihakw as published during the Japanese colonial era, but it lacks uniqueness since it was a translation of Suwenrushiyunqilunao. Another book published during this period was OunyukgiUihakbogam by Cho Wonhui. It brought a heavy influence on the generations to come because it drew up prescriptions through the Gaegun and Gaeggi or Date of Birth of Date of impregnation. It was easy to use and highly potent. The author of this paper also collected about 55 types of Woongi texts published after the liberation of Korea, but there are sure to be many that is missing from the collection.

비골을 이용한 3차원적 하악골 재건 시 가상모의수술 및 입체조형기법을 이용한 골절단 가이드의 활용: 증례보고 (Virtual Surgical Planning and Stereolithography-guided Osteotomy for 3 Dimensional Mandibular Reconstruction with Free Fibula Osseous Flaps: A Case Report)

  • 남웅
    • Maxillofacial Plastic and Reconstructive Surgery
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    • 제34권5호
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    • pp.337-342
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    • 2012
  • The osseous or osteocutaneous free fibula flap has become the gold standard for most mandibular reconstructions because of its favorable osseous characteristics. However, disadvantages, such as the time-consuming reconstructive step, difficulty in performing the osteotomies to precisely recreate the shape of the missing segment of mandible and poor bone-to-bone contact play a role in making the surgeons look for alternative flaps. With the advent of computerized design software, which accurately plans complex 3-dimensional reconstructions, has become a process that is more efficient and precise. However, the ability to transfer the computerized plan into the surgical field with stereolithographic models and guides has been a significant development in advancing reconstruction in the maxillofacial regions. The ability to "pre-plan" the case, mirror and superimpose natural structures into diseased and deformed areas, as well as the ability to reproduce these plans with good surgical precision has decreased overall operative time, and has helped facilitate functional and esthetic reconstruction. We describe a complex case treated with this technique, showing the power and elegance of computer assisted maxillofacial reconstruction from the University of Michigan, Oral and Maxillofacial Surgery.

에지 방향성과 시공간 밝기 변화율을 고려한 시공간 De-Interlacing (Saptio-temporal Deinterlacing Based on Edge Direction and Spatio-temporal Brightness Variations)

  • 정지훈;홍성훈
    • 방송공학회논문지
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    • 제16권5호
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    • pp.873-882
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    • 2011
  • 본 논문에서는 시공간 밝기 변화량에 따라 공간적 보간과 시간적 보간 결과를 가중합하여 주사선을 보간하는 효율적인 디인터레이싱 알고리즘을 제안한다. 공간적 보간에서는 에지 방향성 보정 기능을 포함한 새로운 에지기반 공간적 보간 기법을 적용한다. 일반적으로 기존의 에지를 고려한 공간적 디인터레이싱 알고리즘은 에지의 방향을 잘못 추정할 경우 보간된 영상에서 심각한 화질저하가 발생한다. 이를 보완하고 정확한 에지의 방향을 찾아내기 위해 밝기 차만을 이용한 기존 방법들과는 달리 제안된 방법은 에지 방향성을 검출하고 그 정보에 따라 가중최대빈도수 필터를 이용하여 보간될 화소의 에지의 방향성을 보정한다. 또한, 시간적 변화량 검출 오류를 줄이기 위해 미디언 필터를 적용하여 움직임 검출 성능을 향상시키고, 최종 화소 보간과정에서 시공간적인 밝기 변화량에 따라 공간적 보간과 시간적 보간 결과값의 가중합을 사용하여 움직임이 적은 영역에서의 화질을 향상시킨다. 실험결과 제안된 방법은 기존의 디인터레이싱 방법들에 비하여 주관적 화질뿐만 아니라 객관적인 성능도 우수함을 알 수 있다.

정보 융합 기반 퍼지-베이지안 네트워크 공중 위협평가 방법 (Air Threat Evaluation System using Fuzzy-Bayesian Network based on Information Fusion)

  • 윤종민;최보민;한명묵;김수현
    • 인터넷정보학회논문지
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    • 제13권5호
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    • pp.21-31
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    • 2012
  • 정보 기술의 발전과 더불어 전장상황에서도 정보 시스템들의 고도화가 이루어짐으로써 적기에 대한 정보 획득 및 상황분석은 전장상황에서 주요한 요소가 되었다. 전장상황 분석의 핵심 요소인 위협평가는 피아식별을 통해 식별된 항공 정보를 가지고 해당 상황에 대한 위협치를 평가하여 무기할당에 정보를 제공하는 기술로써, 전장상황의 어느 단계 보다 확실한 정보를 요구하는 단계이다. 전장상황에서 대부분의 위협평가 데이터들은 감지된 센서 값에 의해 연산되어 전달되는데, 기존의 기법들에서 발생할 수 있는 센서 데이터들의 잘못된 연관관계 표현 및 데이터 누락은 전장상황에서의 의사결정에 혼란을 야기 시킬 수 있다. 따라서 각종 센서 데이터들의 연관 관계를 올바르게 정의하고, 센서데이터 누락에 따른 예측 불가능한 전투상황에 대한 신뢰도 높은 위협치 연산 알고리즘을 이용하는 효율적인 의사결정 위협평가 시스템이 필요하다. 본 논문에서는 JDL 정보 융합 모델을 기반으로 애매모호한 관계성을 표현하는데 유리한 퍼지 이론, 데이터 습득의 불확실한 전장상황에서 위협치를 추론하고 상황에 대한 학습이 가능한 베이지안 네트워크를 하이브리드하여 새로운 위협평가 방법을 제안한다. 또, 제안된 방법을 이용하여 가상의 전장 시나리오에 따른 위협평가 결과를 보였다.

레이어 법칙을 활용한 긴 머리형과 중간 머리형의 디자인 연구 (A Study on Layer's Method Applied Long & Middle Hair Design)

  • 박상국;서윤경
    • 한국생활과학회지
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    • 제18권3호
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    • pp.793-798
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    • 2009
  • Hair cut is one of the best useful technical tool for hair styling. In this study using the rule of the layers of hair design, balanced for visual art, perceptual ability and form created by the principles of analysis and offer hair cuts and hair design of the representation of regions and even hair design as the basis of a student of Hair Beauty and all the people working in the field can create a variety of hair design puts the purpose to establish a basis. The result of this study can be outline as follows: First, the step line and the movement of the relationship between the law of the layers above and below the length of the same layer techniques, the same consists of a vertical cross-section of the overall round shape of the cut same layer is created and the appropriate volume and movement, the movement of low-layer round a little bit more feeling and expression is used when you want. High-layer used to want to move a lot of light and could see that. Second, the layer of the Law and over direction, lifting, section, the line control. weight control and analyzed by principle and the principle of the process of forming the written form was unknown. Third, hair design, the expansion of the expressive power of the law of the layers, and the section of the over direction depends on the presence of line control to express the length of the outline I had to, lifting the weight to adjust form controls, and the expression of Hair Design will be expanding the width. A hair designer, a layer style to create a zone he thought the law of the first layer formative area To further the reach will be a lot of research, leading up formative aspects of this research thesis do not have missing parts, or as a result of the Beauty of Hair Design and the width of a hair design education in the field can perform to help feed the reference materials that will be.

Oxidation-induced conformational change of Hsp33, monitored by NMR

  • Lee, Yoo-Sup;Kim, Ji-Hoon;Seo, Min-Duk;Ryu, Kyoung-Seok;Kim, Eun-Hee;Won, Hyung-Sik
    • 한국자기공명학회논문지
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    • 제19권3호
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    • pp.99-105
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    • 2015
  • Hsp33 is a prokaryotic molecular chaperon that exerts a holdase activity upon response to an oxidative stress at raised temperature. In particular, intramolecular disulfide bond formation between the four conserved cysteines that bind a zinc ion in reduced state is known to be critically associated with the redox sensing. Here we report the backbone NMR assignment results of the half-oxidized Hsp33, where only two of the four cysteines form an intramolecular disulfide bond. Almost all of the resolved peaks could be unambiguously assigned, although the total assignments extent reached just about 50%. Majority of the missing assignments could be attributed to a significant spectral collapse, largely due to the oxidation-induced unfolding of the C-terminal redox-switch domain. These results support two previous suggestions: conformational change in the first oxidation step is localized mainly in the C-terminal zinc-binding domain, and the half-oxidized form would be still inactive. However, some additional regions appeared to be potentially changed from the reduced state, which suggest that the half-oxidized conformation would be an intermediate state that is more labile to heat and/or further oxidation.