• 한국식품저장유통학회지
• /
• 제13권4호
• /
• pp.519-523
• /
• 2006

참다래 술(발효주, 리큐르)을 요리용 맛술로 활용하고자 고등어조림과 쇠고기 연육에 처리하여 대한 관능효과를 조사하였다. 그 결과, 조효소 활성은 참다래 발효주와 참다래 리큐르 각각 91.02와 87.56%로 높게 나타났다. TMA함량은 무첨가구의 고등어조림에서 6.60 mg%로 나타났고, 발효주와 리큐르를 첨가하여 고등어조림을 조리하였을 때 각각 4.80과 5.79 mg%로 나타났다. 고등어조림의 관능검사에서는 참다래 발효주와 리큐르 첨가구간이 대조구에 비해 높은 기호특성을 보였고, 쇠고기의 연육효과에서도 참다래 발효주와 참다래 리큐르 첨가구간이 대조구에 비하여 우수한 연화작용을 하는 것으로 나타나 요리용 맛술로의 활용 가능성이 있는 것으로 나타났다.

• Archives of Pharmacal Research
• /
• 제23권1호
• /
• pp.54-58
• /
• 2000

To elucidate the molecular mechanisms for the suppression of LPS-induced nitric oxide (NO) production by a dehydrocostus lactone (DL) from Saussurea lappa, we examined the preventive effect of this compound on $NF-{\kappa}B$ activation in LPS-treated RAW 264.7 macrophages and U937 human monocytic cells. The results suggest that the suppression of NO production is mediated by the inhibitory action on the i-NOS gene expression through the inactivation of $NF-{\kappa}B$ and this sesquiterpene lactone can act as a pharmacological inhibitor of the $NF-{\kappa}B$ activation.

• 천문학회보
• /
• 제38권2호
• /
• pp.78.2-78.2
• /
• 2013

외계행성 연구는 외계생명체 발견과 밀접한 관계가 있으므로 선진국에서는 국가중점연구로 지정하여 연구에 집중하고 있는 기초학문 연구분야다. 기초학문 연구분야이다. 외계행성 연구는 현재까지 발견을 위주로 행해져 왔고, 그 결과 수백 개의 외계행성이 발견되는 성과를 얻을 수 있었다. 최근에는 지구의 크기와 온도에 근접하는 외계행성이 발견이 언론에 소개 되기도 하였다. 외계행성의 분광 연구는 지금까지 그 밝기가 아주 어두운 관계로 Broad band 관측이 주로 행해졌다 (e.g., Swain et al. 2010). 그러나 최근 3-m급 망원경과 중분산 분광기를 사용한 연구에서 구체적인 적외선 분광구조가 드러나게 되었다 (e.g., Waldmann et al. 2012). 따라서 앞으로 GMT의 분광기를 사용하여 상당히 구체적인 분광구조 관측이 가능하리라고 예측 할 수 있게되었다. 이번 발표에서는 GMT분광기들을 사용한 외계행성 적외선 분광 연구를 원활히 수행하기 위한 준비 단계로 태양계 행성에 대한 국내외 적외선 분광 연구 현황을 논의 하고자 한다.

• Biomolecules & Therapeutics
• /
• 제8권1호
• /
• pp.22-26
• /
• 2000

In order to study the cytotoxic properties of sesquitepenes, dehydrocostus lactone (DL) and costunolide from Saussurea lappa, cytotoxicity was measured by SRB method using various human cancer cell lines. Dehydrocostus lactone(DL) and costunolide exhibited significant cytotoxicity against A-549, SK-OV-3, SK-MEL-2, XF-498 and HCT 15 cells. The U937 human leukemia cells treated with DL showed several apoptotic evidences like chromosome condensation and formation of apoptotic bodies. From the results of FACS analysis, early apoptosis was observed by phosphatidylserine externalization detected by annexin V-FITC. Furethermore, these studies determined hypodiploid contents and effects on the cell phase distribution of DL-treated U937 cells. After exposure of U937 cells to $30\mu\textrm{M}$ DL effectively led to G2/M modified cell cycle distribution within 24hr. These observations suggest that DL can be used efficiently for the cancer treatment.

• Child Health Nursing Research
• /
• 제23권4호
• /
• pp.534-542
• /
• 2017

Purpose: The purpose of this study was to identify the factors that affect nursing students' perception of pediatric safety nursing activities for children during hospitalization. Methods: The study sample included 304 nursing students who had participated in pediatric nursing practice. Data were analyzed using SAS 9.3 program. Results: Regression analysis showed that the model's explanatory power was 37%. Safety policy and procedure, safety priority, disaster experience, and knowing a place of refuge were factors affecting the perception of safety nursing activities for children during hospitalization. Conclusion: Findings show that safety policy and procedures and safety priority are major factors that affect the perception of safety nursing activities and indicate that effective education programs on safety policy and procedure and safety priority are necessary to improve the perception of safety nursing activities.

• Biomolecules & Therapeutics
• /
• 제25권6호
• /
• pp.569-577
• /
• 2017

Sepsis is a syndrome characterized by systemic inflammatory responses to a severe infection. Acute hyper-inflammatory reactions in the acute phase of sepsis have been considered as a primary reason for organ dysfunction and mortality, and advances in emergency intervention and improved intensive care management have reduced mortalities in the early phase. However it has been recognized that increased deaths in the late phase still maintain sepsis mortality high worldwide. Patients recovered from early severe illness are unable to control immune system with sepsis-induced immunosuppression such as immunological tolerance, exhaustion and apoptosis, which make them vulnerable to nosocomial and opportunistic infections ultimately leading to threat to life. Based on strategies to reverse immunosuppression, recent developments in sepsis therapy are focused on molecules having immune enhancing activities. These efforts are focused on defining and revising the immunocompromised status associated with long-term mortality.

• 전력전자학회:학술대회논문집
• /
• 전력전자학회 2017년도 전력전자학술대회
• /
• pp.335-336
• /
• 2017

본 논문에서는 대용량 배터리 모듈이 병렬 연결되어 있는 에너지 저장장치 시스템의 초기 기동 조건시 투입 초기의 전류를 추정할 수 있는 방법을 제시한다. 제안된 방법은 배터리 모듈을 구성하고 있는 리튬 배터리 모듈의 단자 전압 및 배터리 모듈 저항 데이터를 이용하여 병렬 연결하고자 하는 배터리의 전류를 예측하는 방법으로써 배터리 모듈의 기동 투입 가능여부 등 온 오프 시퀀스 로직에 적용할 수 있다.

• 대한금속재료학회지
• /
• 제48권8호
• /
• pp.699-704
• /
• 2010

We investigated the cryogenic temperature plasticity of a bulk amorphous alloy. Experiments showed that as temperature decreases, the plasticity of the alloy increases, such that the alloy exhibited ~20% of plastic strain when tested at $-196^{\circ}C$. This enhancement in the plasticity at cryogenic temperatures was associated with the formation of abundant shear bands distributed uniformly over the entire surface of the sample. Nonetheless, the serrations, the characteristic feature of the plastic deformation of amorphous alloys, were unclear at $-196^{\circ}C$. In this study, both the enhanced plasticity and the unclear serrations exhibited by the amorphous alloy at cryogenic temperatures were clarified by exploring shear banding behaviors in the context of the velocity and the viscosity of a propagating shear band.

• 한국가시화정보학회지
• /
• 제15권3호
• /
• pp.14-19
• /
• 2017

Increase of blood viscosity significantly changes the flow resistance and wall shear stress which are related with cardiovascular diseases. For measurement of blood viscosity, microfluidic method has proposed by monitoring pressure between sample and reference flows in the downstream of a microchannel with two inlets. However, it is difficult to apply this method to unknown flow conditions. To measure blood viscosity under unknown flow conditions, a microfluidic method based on micro particle image velocimetry(PIV) is proposed in this study. Flow rate in the microchannel was estimated by assuming velocity profiles represent mean value along channel depth. To demonstrate the measurement accuracy of flow rate, the flow rates measured at the upstream and downstream of a T-shaped microchannel were compared with injection flow rate. The present results indicate that blood viscosity could be reasonably estimated according to shear rate by measuring the interfacial width and flow rate of blood flow. This method would be useful for understanding the effects of hemorheological features on the cardiovascular diseases.

• 천문학회보
• /
• 제39권1호
• /
• pp.66.1-66.1
• /
• 2014

Radiative transfer programs to simulate the 3-micron auroral $CH_4$ emissions of Jupiter have been developed. The formalism of the radiative transfer calculations including the thermal, fluorescent, and auroral emissions of the $CH_4$ bands for an atmospheric layer having an optical depth of ${\tau}_v$ is given by: ${\mu}dI_v/d{\tau}_v=I_v-{\varpi}_v{^*}J_v(1-{\varpi}_v{^*})B_v-{\varpi}{^*}F_{ov}{e}{x}{p}(-{\tau}_v/{\mu}_o)4{\pi}-hv{\varpi}{^*}V/4{\pi}$ where ${\varpi}_v{^*}$ is the single scattering albedo of $CH_4$ consisting of Einstein A coefficient and collisional deexcitation rate. Other terms are usual radiative transfer parameters appearing in textbooks including the terms for scattered ${\varpi}_v{^*}J_v$, thermal $(1-{\varpi}_v{^*})B_v$, and attenuated solar radiations $F_{ov}$ at the certain atmospheric layer. For auroral excitations, we include V, which is the number of excited states per $cm^3$ persec by auroral particle bombardments. We apply this formalism to the high-resolution spectra of the auroral regions observed with GNIRS/Gemini North, and will present preliminary results for the 3 micron auroral processes of Jupiter.