• KOREAN JOURNAL OF CROP SCIENCE
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• v.45 no.6
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• pp.370-373
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• 2000

Acute toxicity of the pigment fraction of Heugjinjubyeo was investigated in male and female mice following oral administration. Major component of pigment fraction was analyzed as cyanidin 3-glucoside (C3G), which composition content was 96%. The pigment fraction as given at the single oral doses of 1000,3000 and 9000mg/kg in male and female mice did not show any abnormal behaviours, body weight loss or other toxic symptoms during observation period of 14 days. There were no dead mice among 6 mice at a single dose of 9000mg/kg. Thus, it is concluded that the minimum lethal doses (MLD) of the pigment extract might be more than 9000 mg/kg p.o., in male and female mice.