• International Journal of Control, Automation, and Systems
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• 제2권2호
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• pp.228-237
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• 2004

This paper provides a motion analysis of soft-fingertip object manipulation tasks by presenting a dynamic model of multi-fingered object manipulations with soft fingertips. It is fundamentally observed that soft fingertips employed in a multi-fingered hand generate some deformation effects during the manipulation process and also that those effects are closely related to the behavior of the manipulated object. In order to analyze the motion of using soft fingertips, a dynamic manipulation control scheme is presented. Simulation and experimental results demonstrate the motion of soft-fingertips applied in object manipulating tasks and are further used to discuss the characteristics of soft-fingertip motions.

• International Journal of Contents
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• 제8권1호
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• pp.10-15
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• 2012

Since MegaStudy started e-learning business for Korean high school students, the Korean e-learning industry began to expand and steadily gain attention. This paper focused on the analysis of the development of the Korean e-learning business for teens and the growth of MegaStudy. The three institutional mechanisms were used to examine the factors that aided the development of the business. The regulatory mechanism was the government policy to prevent the expansion of the offline private education sector, which greatly aided the growth of the e-learning business. The mimetic mechanism was the notion to mimic the characteristics of the Korean e-business initiatives. The normative mechanism involved the widespread social norm suggesting that every student should be given an equal opportunity of private education. This paper also examined the case of MegaStudy as a successful case of the e-learning companies. It analyzed the business model of MegaStudy, which is based on its advantage as the front-runner and its high-quality contents and services.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2014년도 제46회 동계 정기학술대회 초록집
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• pp.132.1-132.1
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• 2014

Fluorescent-magnetic nanoclusters were synthesized for biomedical applications. The nanoclusters consisted of superparamagnetic core-nanoclusters, highly fluorescent shell of nanocrystals, and lipid A. Magnetic cores were used for both magnetic resonance imaging (MRI) and cell separation. Fluorescent shell was used for optical imaging. The lipid-A-loaded nanoclusters were up-taken by dendritic cells via phagocytosis, which successfully activated dendritic cells. The dendritic cells were migrated to lymph nodes and spleen of mice. The results showed that our novel nanoclusters can play a role as an efficient optical and magnetic imaging, a cell separating and a pathogen mimetic agent at the same time. Additionally, synthesis of wavelength conversion nanowires will be discussed, which may be used as an optical nanoprobe in biological studies.

• International Journal of Fuzzy Logic and Intelligent Systems
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• 제9권4호
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• pp.333-338
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• 2009

This paper presents a task-based analysis on the number of independent robotic fingers required for compliant manipulations. Based on the stiffness relation between operational space and fingertip space of a multi-fingered object manipulating system, we describe a technique for modulation of the fingertip stiffness without inter-finger coupling so as to achieve the desired stiffness specified in the operational space. Thus, we provides a guide line how many fingers are basically required for successful multi-fingered compliant tasks. Consequently, this paper enables us to assign effectively the number of fingers for various compliant manipulations by robot hands.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2014년도 추계학술발표대회
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• pp.913-916
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• 2014

본 논문의 수중로봇 도미(Domi) ver1.0는 관상어용 물고기 로봇 개발을 목표로 연구 개발되었다. 물고기 로봇은 머리, 1단, 2단 몸체와 꼬리부분과 2개의 구동 관절로 구성되어 있다. 물고기 로봇의 추력에 적합한 구동부 선정을 위하여 물고기 로봇 모델링과 유영 해석을 통하여 관절 구동부가 설계되었다. 또한 물고기 로봇의 유영알고리즘은 Lighthill 운동학 해석을 기초로 생체 모방의 유영 근사화 방법을 적용하였다. 설계된 물고기는 수동유영 및 자율운영모드로 동작된다. 수동유영모드는 RF 송수신에 의하여 구현된다. 본 설계된 물고기로봇 도미 ver1.0은 수중 현장시험 평가을 통하여 추력, 내구성, 방수성 등의 성능이 우수함을 확인하였다.

• Archives of Pharmacal Research
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• 제26권9호
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• pp.723-726
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• 2003

Five coumarins, isoimperatorin (1), pabulenol (2), isooxypeucedanin (3), oxypeucedanin hydrate (4) and osthol (5) were isolated from the MeOH extract of Angelica genuflexa in the course of searching for anti-platelet and anti-coagulant components from plants. Pabulenol (2) was isolated from A. genuflexa for the first time. The five compounds isolated from A. genuflexa, together with decursinol angelate (6), decursin (7) and nodakenin (8) from A. gigas were evaluated for their effects on platelet aggregation and blood coagulation. Compounds 2, 5, 6 and 7 were observed to be either equally effective or 2∼4 times more inhibitory than ASA in both arachidonic acid and U46619 ($TXA_2$ mimetic) induced platelet aggregations.

• 비교문화연구
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• 제21권
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• pp.289-306
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• 2010

In Jamaica Kincaid's novel Lucy, the narrator grows up with the burden of colonial legacies embedded with Englands' imperial disciplinary projects, its language, educational institutions, discourses. Colonial education interpellates the narrator into a colonial subject through its multiple ideological discourses and systems. Teaching the literature of England is the most insidious form of the Empire's disciplinary colonial projects, more powerful than military enforcement: Its mode of operation is creating phantasy and instigating and planting desire for such phantasy. As Homi Bhabha aptly theorizes as colonial mimicry and ambivalence, the narrator as colonial subject grows up split and confused as an ambivalent subject, simultaneously mimicking and desiring for the phantasized England as real, while resisting and criticizing such up-bringing and mimetic desire. This paper explores Kincaid's rhetorical strategy of employing Wordsworth's poem, "I Wandered as a Lonely Cloud," especially her use of the flower "daffodil." Employing the concept of "daffodil gap" suggested by postcolonial critics, this paper closely examines two episodes involving the flower daffodil in the novel, one in a colonial classroom and the other in a garden in a new world and suggests that Kincaid accomplishes intertextual critique of colonial education and imperial projects.

• Bulletin of the Korean Chemical Society
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• 제19권2호
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• pp.189-193
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• 1998

Carboxypeptidase-B (CPB) is involved in the biosynthesis of numerous peptide hormones and neurotransmitters. CPB catalyzes hydrolysis of the basic amino acids from the C-terminal position in polypeptides during posttranslational prohormonal processing. Various peptides containing thiaarginine residue at C-terminal position were synthesized and tested for their hydrolysis by CPB. A colorimetric assay, employing Ellman's reagent to detect the thioguanidine released upon hydrolysis of the dipeptide substrates, showed that thiaarginine is a suitable mimetic for arginine. Kinetic studies on the four substrates, Z-L-Ala-DL-thia-Lys, Z-L-Ala-DL-thia-Arg, Z-L-Lys-DL-thia-Arg, and Z-L-Lys(Boc)-DL-thia-Arg, gave Km (mM) of 0.66, 5.08, 0.024, and 0.006 and kcat (min-1) of 340, 5200, 151 and 335, respectively.

• International Journal of Stem Cells
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• 제16권3호
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• pp.251-259
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• 2023

Mesenchymal stromal cells (MSCs) have attracted scientific and medical interest due to their self-renewing properties, pluripotency, and paracrine function. However, one of the main limitations to the clinical application of MSCs is their loss of efficacy after transplantation in vivo. Various bioengineering technologies to provide stem cell niche-like conditions have the potential to overcome this limitation. Here, focusing on the stem cell niche microenvironment, studies to maximize the immunomodulatory potential of MSCs by controlling biomechanical stimuli, including shear stress, hydrostatic pressure, stretch, and biophysical cues, such as extracellular matrix mimetic substrates, are discussed. The application of biomechanical forces or biophysical cues to the stem cell microenvironment will be beneficial for enhancing the immunomodulatory function of MSCs during cultivation and overcoming the current limitations of MSC therapy.

• 만화애니메이션 연구
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• 통권30호
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• pp.169-199
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• 2013

만화에서의 다양한 연출은 웹툰의 대중화와 함께 세로 스크롤 연출이 기존의 출판만화의 페이지 연출과 대립하는 양상을 보이며 새로운 장르를 구축해냈다. 많은 출판만화의 연구가 페이지를 위시한 컷 연출에 초점을 두고 있지만, 웹툰에는 페이지의 개념이 없다. 대중 지향의 만화는 시대의 변화에 따라 구심점이 지면에서 컴퓨터 모니터로 옮겨가며 매체의 특성 또한 달라졌으며, 매체는 점점 다원화되고 있다. 스마트폰의 유행으로 인한 모바일의 강세, 공교육에서의 태블릿 PC의 보급화 전망과 같이, 만화는 급변하는 매체환경에 속해있다. 이러한 상황에서도 만화의 변하지 않는 중요한 정체성중의 하나를 꼽자면 그림과 텍스트의 조합이 만들어 내는 연출이다. 이 논문에서는 허영만의 작품을 중심으로 만화 의태어인 효과태가 가진 상징어적인 특성과 효용가치를 분석하였다. 효과태는 단지 소리뿐만이 아니라 모양, 느낌, 상태 등을 전달하며 문학적 상상구조를 발동시킴으로써 함축적 특성을 가진다. 현대국어의 장점인 다양한 언어 표현과 자모체계는 미세한 어감과 정서의 차이점을 느끼게 해주며 직접 경험과 간접 경험을 통한 기억을 떠올려서 뉘앙스화하기 때문이다. 이러한 특징들로 인해서 허영만의 대표작들은 상업성과 작가성을 동시에 지니고 오랜 세월동안 대중과의 소통을 해왔으며 한국적인 만화의 소양을 풍부하게 가지고 있다. 허영만의 만화에 나타난 효과태의 특징은 만화의 표현과 전달에 있어서 일반적인 기대 이상으로 효과태가 미치는 영향이 크다는 것을 알 수가 있다. 피수용자인 독자는 그림과 글 사이에서 적극적으로 지적인 추리를 하면서 그 과정 자체를 즐기며, 그러한 과정에 대사 텍스트 이상으로 상상력을 자극하는 장치가 효과태이며, 효과태는 상징적 구조를 장점으로 하는 독자의 능동적 참여 장치이다.