• Title/Summary/Keyword: Military biomedical research

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Ethics Involving Human Subject Research in Military Medicine (군진의학 연구에서 인간대상 연구윤리)

  • Kwon, Ivo
    • The Journal of KAIRB
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    • v.4 no.2
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    • pp.23-29
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    • 2022
  • The goal of the military medicine is not as same as that of the civil medical practice, and consequently the characteristics of military biomedical researches have their own uniqueness. In front of the prerogative of national defense, some of the human rights ordinarily ensured in normal researches with human subjects are not to be fully guaranteed. The hierarchic system of the military would complicate the issue when the soldiers are enrolled as human subject for the research. Some researches could be classified as a military secret, therefore, the confidentiality issues need to be well addressed. Institutional Review Board and review procedure should be modified for the military purposes. So, it is necessary to establish the appropriate regulatory system for the military biomedical researches with human subject to manage the complicated issues involved in them.

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Impact of the COVID-19 vaccine booster strategy on vaccine protection: a pilot study of a military hospital in Taiwan

  • Yu-Li Wang;Shu-Tsai Cheng;Ching-Fen Shen;Shu-Wei Huang;Chao-Min Cheng
    • Clinical and Experimental Vaccine Research
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    • v.12 no.4
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    • pp.337-345
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    • 2023
  • Purpose: The global fight against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has led to widespread vaccination efforts, yet the optimal dosing schedule for SARS-CoV-2 vaccines remains a subject of ongoing research. This study aims to investigate the effectiveness of administering two booster doses as the third and fourth doses at different intervals to enhance vaccine protection. Materials and Methods: This study was conducted at a military regional hospital operated by the Ministry of National Defense in Taiwan. A cohort of vaccinated individuals was selected, and their vaccine potency was assessed at various time intervals following their initial vaccine administration. The study participants received booster doses as the third and fourth doses, with differing time intervals between them. The study monitored neutralizing antibody titers and other relevant parameters to assess vaccine efficacy. Results: Our findings revealed that the potency of the SARS-CoV-2 vaccine exhibited a significant decline 80 days after the initial vaccine administration. However, a longer interval of 175 days between booster injections resulted in significantly higher neutralizing antibody titers. The individuals who received the extended interval boosters exhibited a more robust immune response, suggesting that a vaccine schedule with a 175-day interval between injections may provide superior protection against SARS-CoV-2. Conclusion: This study underscores the importance of optimizing vaccine booster dosing schedules to maximize protection against SARS-CoV-2. The results indicate that a longer interval of 175 days between the third and fourth doses of the vaccine can significantly enhance the neutralizing antibody response, potentially offering improved protection against the virus. These findings have important implications for vaccine distribution and administration strategies in the ongoing battle against the SARS-CoV-2 pandemic. Further research and largescale trials are needed to confirm and extend these findings for broader public health implications.

Embodiment of living body measure system modelling for rehalibitation treatment of positive simulation for HRV algorithm analysis interface of Mobile base (모바일기반의 HRV 인터페이스에 처리에 대한 생체계측 시스템 모델링의 구현)

  • Kim, Whi-Young
    • Proceedings of the IEEK Conference
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    • 2006.06a
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    • pp.1013-1014
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    • 2006
  • Mobilecomputer offers more fundamental role than role assistance enemy of modern technology equipment and new Information Technology can reconsider, and reconstruct creatively accuracy of physiological concept. That military register symptoms are developed of disease, before far before rehalibitation, offer possibility that can intervene in process that motive change of military register symptoms after rehalibitation. But, that many parameters become analysis target and mathematical settlement and equalization system of neted data of that is huge, same time collection of all datas can lift difficulty etc.. These main weakness puts in structural relation between elements that compose system. Therefore, dynamics research that time urea of systematic adjustment has selected method code Tuesday nerve dynamics enemy who groping of approach that become analysis point is proper and do with recycling bioelectricity signal. Nature model of do living body signal digital analysis chapter as research result could be developed and scientific foundation groping could apply HSS (Hardware-software system) by rehalibitation purpose. Special quality that is done radish form Tuesday of bioelectricity signal formation furthermore studied, and by the result, fundamental process of bodysignal in do structure circuit form of analog - digital water supply height modelling do can

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Association between Blood Mercury and Seafood Consumption in Korean Adults: KoNEHS Cycle 4 (2018~2020)

  • Ji-Eun Oh;Tae-Hyeong Kim;Eun-Hee Lee
    • Biomedical Science Letters
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    • v.30 no.1
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    • pp.24-31
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    • 2024
  • Mercury is a chemical pollutant widely present in the environment. Humans are generally exposed to mercury in the form of organic Hg (methylmercury) through the consumption of seafood. Koreans enjoy eating fish therefore blood mercury concentration is usually higher than in developed countries. By investigating blood mercury concentration according to the frequency of seafood consumption and sociodemographic factors, we aimed to identify recent trends in blood mercury concentration in Korean adults. This study was conducted using KoNEHS cycle 4 (2018~2020) from the National Institute Environmental Research Survey. The geometric mean concentration of blood mercury of the subjects was 2.959 (±1.018) ㎍/L, which was significantly higher in men than in women. It was observed that as the frequency of fish and shellfish consumption increased, the blood mercury concentration increased. In adjusted logistic regression, fish consumption was associated with 36.7% increased risk of blood mercury levels [Odds ratio, 1.367; 95% confidence interval (CI), 1.246~1.500], and shellfish consumption was associated with 26.5% increased risk of blood mercury levels [Odds ratio, 1.265; 95% confidence interval (CI), 1.134~1.410]. Blood mercury concentration was also found to increase as the socioeconomic level increased. In conclusion, the geometric mean concentration of blood mercury was increased compared to the one in the 3rd KoNEHS (2015~2017) and seafood consumption and socioeconomic level were still significantly associated with increasing blood mercury concentration in Korea. Therefore, it is necessary to encourage healthy seafood consumption habits and conduct continuous monitoring considering various factors to reduce blood mercury levels.

Design optimization of a fixed wing aircraft

  • Yayli, Ugur C.;Kimet, Cihan;Duru, Anday;Cetir, Ozgur;Torun, Ugur;Aydogan, Ahmet C.;Padmanaban, Sanjeevikumar;Ertas, Ahmet H.
    • Advances in aircraft and spacecraft science
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    • v.4 no.1
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    • pp.65-80
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    • 2017
  • Small aircrafts, Unmanned Aerial Vehicles (UAVs), are used especially for military purposes. Because landing fields are limited in rural and hilly places, take-off or landing distances are very important. In order to achieve a short landing or take-off distance many parameters have to be considered, for instance the design of aircrafts. Hence this paper represents a better design to enlarge the use of fixed wing aircrafts. The document is based on a live and simulated experiments. The various components of designed aircraft are enhanced to create short take-off distance, greater lift and airflow without the need for proper runway area. Therefore, created aerodynamics of the remotely piloted aircraft made it possible to use fixed wing aircrafts in rural areas.

Embodiment of living body measure system modelling for rehalititation treatment of simulation for HRV analysis interface of PDA base (PDA기반의 HRV분석 인터페이스에 대한 시뮬레이션의 재활치료용 생체계측 시스템 모델링의 구현)

  • Kim, Whi-Young;Choe, Jin-Yeong;Park, Seong-Jun;Kim, Jin-Yeong;Park, Seong-Jun;Kim, Hui-Je
    • Proceedings of the KIEE Conference
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    • 2006.07d
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    • pp.2167-2168
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    • 2006
  • Mobilecomputer of offers more fundamental role than role assistance enemy of modem technology equipment and new Information Technology can reconsider, and reconstruct creatively accuracy of physiological concept. That military register symptoms are developed of disease, before far before rehalibitation, of for possibility that can intervene in process that motive change of military register symptoms after rehalibitation. But, that many parameters become analysis target and mathematical settlement and equalization system of noted data of that is huge, same time collection of all datas can lift difficulty etc.. These main weakness puts in structural relation between elements that compose system. Therefore, dynamics research that time urea of systematic adjustment has selected method code Tuesday nerve dynamics enemy who groping of approach that become analysis point is proper and do with recycling bioelectricity signal. Nature model of do living body signal digital analysis chapter as research result could be developed and scientific foundation groping could apply HSS (Hardware-software system) by rehalibitation purpose. Special quality that isdone radish form Tuesday of bioelectricity signal formation furthermore studied, and by the result, fundamental process of bodysignal in do structure circuit form of analog - digital water supply height modelling do can.

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Research of the Objective Quality Comparison of Underwater Cameras (수중 촬영용 카메라의 객관적 화질 비교에 관한 연구)

  • Ha, Yeon-Chul;Park, Jun-Mo
    • Journal of the Institute of Convergence Signal Processing
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    • v.21 no.2
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    • pp.92-100
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    • 2020
  • Currently, the demand for underwater or underwater photography is growing very fast. Its coverage of underwater shooting for broadcasting, leisure and sports, and military and operational use is also growing rapidly. Among them, we specifically select the best camera to be used in underwater drones to photograph and inspect marine life attached to the ship's hull. To compare three cameras performance, they are compared and evaluated using objective and subjective criteria in special circumstances such as underwater shooting. This study checks whether performance criteria, such as resolution of a camera, meet objective and subjective standards in the unusual situation of underwater shooting. And it shows that in addition to the filter that calibrates the image, proper camera selection is important for providing good picture quality. Even after this study, research using more diverse cameras could provide an appropriate standard for comparison of underwater camera quality.

Gait Type Classification Based on Kinematic Factors of Gait for Exoskeleton Robot Recognition (외골격 로봇의 동작인식을 위한 보행의 운동학적 요인을 이용한 보행유형 분류)

  • Cho, Jaehoon;Bong, wonwoo;Kim, donghun;Choi, Hyeonki
    • Journal of Biomedical Engineering Research
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    • v.38 no.3
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    • pp.129-136
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    • 2017
  • The exoskeleton robot is a technology developed to be used in various fields such as military, industry and medical treatment. The exoskeleton robot works by sensing the movement of the wearer. By recognizing the wearer's daily activities, the exoskeleton robot can assist the wearer quickly and efficiently utilize the system. In this study, LDA, QDA, and kNN are used to classify gait types through kinetic data obtained from subjects. Walking was selected from general walking and stair walking which are mainly performed in daily life. Seven IMUs sensors were attached to the subject at the predetermined positions to measure kinematic factors. As a result, LDA was classified as 78.42%, QDA as 86.16%, and kNN as 87.10% ~ 94.49% according to the value of k.