A novel gene, designated mgt-6, containing four splicing variants, was isolated from a gene trap clone library of C3H/10T1/2 cells transfected with retroviral promoterless gene-trap vector, ROSAFARY. The transcript variants were differentially expressed in murine tissues and cell lines and differentially responded to diverse stimuli including TGF-${\beta}1$ and mitogen-activated protein kinase (MAPK) inhibitors. The mgt-6 gene encoded a protein of 37 or 11 amino acid residuals with cytoplasmic distribution. However, when C3H/10T1/2 cells were treated with 5-azacytidine, the protein translocated into cell nucleus as indicated by fused LacZ or C-terminally tagged EGFP. Our preliminary results suggest that further study on the role of mgt-6 gene in cell transformation and differentiation may be of significance.
Background: Several large outbreaks have demonstrated the threat of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) in close-contact environments, such as occurs during training and quartering of military recruits training. In South Korea, which is a hospital or healthcare-associated MRSA prevalent area, military service is compulsory for all healthy young men. We surveyed and determined the extent of CA-MRSA colonization in the upper respiratory tracts of Korean military recruits. Methods: The Korean military recruits who were enrolled in a military training facility from November 2004 to March 2005 were eligible for this study. Sputum or nasopharyngeal swap was obtained from randomly selected subjects who displayed upper respiratory tract symptoms. Results: Of the 181 participants, 32 participants (17.7%) were colonized with S. aureus, and 12 participants (6.6%) were colonized with MRSA. Among the cases that were colonized with S. aureus, 37.5% (12/32) were colonized with MRSA. Antimicrobial susceptibility testing showed resistant patterns that were suggestive of the CA-MRSA strains for all of the MRSA isolates. Conclusion: This study of Korean military recruits found a great deal of showed MRSA colonization in them, and the antimicrobial resistant profile that was suggestive of a CA-MRSA strain. Further efforts to prevent the spread of MRSA infections and careful monitoring for CA-MRSA outbreaks are warranted, especially in a high risk group such as military recruits.
Objectives : Military Medicine, as its name suggests, deals with the subject of medicine in military settings. War has always been part of human history, and continues to be so even to this date. As such, many soldiers who take part in battles suffer from, or under the danger of, trauma and disease. Very few records in Korea deal with military medicine. Through a research, however, it was discovered that Euibangyuchwi and Hyangyakjipseongbang contains a number of mentions regarding the subject matter. As such, the paper will review military medicine as mentioned in Euibangyuchwi and Hyangyakjipseongbang. Methods : Bingbushouji as discovered in Euibangyuchwi and Hyangyakjipseongbang was reviewed and its main treatment, origin, usage, and reference were categorized and given considerations. Results : Bingbushouji was referened 29 times in Euibangyuchwi and 22 times in Hyangyakjipseongbang. In most instances, Bingbushouji was used as simple prescription, and its usage mainly revolved around the exterior of human body, such as applying directly on the skin. Conclusions : A study of the texts in Euibangyuchwi and Hyangyakjipseongbang revealed that Bingbushouji was put together to treat the ailments and diseases of the soldiers during wartime, and to provide treatment to soldiers and non-combatants statying in a region where medical expertise is scarce.
During a military service, noise has unusual characteristics, and constitutes a serious hazard to hearing of military servicemen. The purpose of this study is to understand the use of hearing protection and to assess the safety effects of hearing protection by using a ear plug in military. A total of 208(the army : 101, an air force : 107) serviceman were studied utilizing a questionnaire to know how many serviceman use the hearing protection and a total of 202(the army : 110, an air force : 92) serviceman were also studied using a ear fit validation device to assess the safety effects of hearing protection by using a ear plug. The results showed that the army have low used of hearing protection than an air force because of the low frequency of the noise exposure in the army. Personal attenuation rate was increased with 8 dB after fitting education. Therefore, it is recommended that use of proper hearing protection and fitting education was more suitable for military servicemen who were being exposed of the noise in domestic military.
Purpose: In the Korean armed forces, vaccination against tetanus is done when personnel join the military service, but we do not know how many military personnel are vaccinated and how many soldiers have protection against tetanus. We performed a qualitative analysis of the tetanus antibody in Korean military personnel by using the TQS (Tetanus Quick Stick) Methods: This study used a prospective collection method for military personnel visiting to the emergency department of a tertiary armed forces hospital from July 2005 to January 2007. We performed an analysis by using the TQS and asked whether the personnel had been inoculated during military service. Results: The number of enrolled military personnel was 474. Among them, 412 had been vaccinated against tetanus after entering the military service. The positive rate of TQS was 91.3% (373 patients) after vaccination for tetanus. Conclusion: Many military personnel were inoculated with tetanus toxoid during military service and have protective antibodies for tetanus. According as TQS should be used for military personnel who visit the emergency department of an armed forces hospital. Also, anti-tetanus immunoglobulin should not normally be used a positive TQS for tetanus prophylaxis.
Journal of the Korean Society of Physical Medicine
/
v.19
no.3
/
pp.21-27
/
2024
PURPOSE: This study compared the grip strength of young adult male soldiers who had undergone military training with civilian adult males by indirectly examining the impact of military training on the grip strength and overall muscle mass. Grip strength, an essential biomarker for overall health and crucial combat abilities, was explored within the demanding conditions of military service. METHODS: The research measured the grip strength of soldiers actively serving in the military and compared it with data from healthy civilian males in their twenties to determine if a structured training regime significantly enhances grip strength more than a typical civilian lifestyle. The data were analyzed using descriptive statistics with the means and group differences assessed using a t-test (p < .05). An online survey was conducted among the military group to self-assess the changes in grip strength before and after enlistment to gauge the awareness of such changes. RESULTS: Significant differences were observed between the groups, with an observable increase in grip strength with age within the military group, suggesting that military training can positively impact muscle maintenance and enhance daily life. CONCLUSION: Further research will be needed to elucidate the effects of military physical training programs and their broader implications for military readiness and overall health.
To test if exposure history to rifle fire or cannonade training during military duty can induce hearing loss, history of personal military service and histroy of gunshot exposure were asked to 228 male college students with self -administrative questionnaire. Otoscopic examination and Rinne's test were performed if any abnormal finding was detected by pure-tone audiometry. Average hearing threshold levels of 500 Hz, 1,000 Hz, 2,000 Hz, 4,000 Hz and threshold levels at 4,000 Hz were calculated for 112 students who were remained after exclusion of cases with history of ear disease, of ototoxic drug administration, and of neuropsychiatric disease, and mean of those were compared between group of students who have completed military duty (completed group) and group of those who have not (not-completed group), and between group exposed (exposed group) and group unexposed to gunshot sound (unexposed group). Mean of average hearing threshold level and mean of threshold levels at 4,000 Hz of completed group and those of exposed group were higher than those of not-completed group and unexposed group, respectively. Proportion of cases that average threshold level was greater than 40 dB or threshold levels at 4,000 Hz was greater than 50 dB were higher also in completed group and exposed group than in duty not-completed group and unexposed group, respectively Multiple linear regression analysis including age, duration of military service, degree of gunshot sound exposure as independant variables and average hearing threshold level as dependant variable, was performed in order to estimate the effect of age on hearing, and any considerable effect of age on hearing could not be found. In conclusion, hearing impairment can be induced by rifle fire or cannonade training.
Park, Sang-Young;Han, Chang-Huyn;Ahn, Sang-Young;Kwon, Oh-Min;Ahn, Sang-Woo
Journal of Korean Medical classics
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v.23
no.1
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pp.31-46
/
2010
This research is aimed at contriving to expand to its base on the research work Military medicine in East Asia by introducing GunjungUihak(means Military medicine) and adding translations and commentaries to it and propagating to academic circles. GunjungUihak is the only technical book on GunjungUihak which was written for the purpose of treating soldiers in time of war. One of the characteristics shown in its prescription is convenience in medical treatment; the writer of GunjungUihak Wangmyeonghak(王鳴學) edited pills and a powdered medicine to be prescribed in large proportions so that they could be used urgently in the situation of battles at a viewpoint of a general while collecting knowledge of medicine. In addition, this book is compiled with a very short edition with one volume and 18 units. Including only a little amount in the book means that it was compiled by extracting only the contents needed in preparation for the wartime emergency, and such a measure was taken for military surgeons to carry it with facility during the time of war. In addition, much weight of this book was given to the diseases caused by environment with which soldiers came in contact in time of combat, not the wounds by the weapons of war as specified from the beginning of the book, which suggests that the environmental factor of the friendly forces was much more threatening than the arms of enemy troops in the situation of a combat. Like this, GunjungUihak is a material of great value in that it is showing a model of the aspects of Military medicine in East Asia at that time even in its fragmentary writings and it has been preserved by Korea.
Objectives: The aim of this study was to examine the levels of serum 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and evaluate their association with age, body mass index, smoking, military record-based variables, and estimated exposure to Agent Orange in Korean Vietnam veterans. Methods: Serum levels of TCDD were analyzed in 102 Vietnam veterans. Information on age, body mass index, and smoking status were obtained from a self-reported questionnaire. The perceived exposure was assessed by a 6-item questionnaire. Two proximitybased exposures were constructed by division/brigade level and battalion/company level unit information using the Stellman exposure opportunity index model. Results: The mean and median of serum TCDD levels was 1.2 parts per trillion (ppt) and 0.9 ppt, respectively. Only 2 Vietnam veterans had elevated levels of TCDD (>10 ppt). The levels of TCDD did not tend to increase with the likelihood of exposure to Agent Orange, as estimated from either proximity-based exposure or perceived self-reported exposure. The serum TCDD levels were not significantly different according to military unit, year of first deployment, duration of deployment, military rank, age, body mass index, and smoking status. Conclusions: The average serum TCDD levels in the Korean Vietnam veterans were lower than those reported for other occupationally or environmentally exposed groups and US Vietnam veterans, and their use as an objective marker of Agent Orange exposure may have some limitations. The unit of deployment, duration of deployment, year of first deployment, military rank, perceived self-reported exposure, and proximity-based exposure to Agent Orange were not associated with TCDD levels in Korean Vietnam veterans. Age, body mass index and smoking also were not associated with TCDD levels.
Due to Japanese imperialism's invasion of Korea and the policy of exterminating national culture, many independence activists from Korean medicine participated in the Manchurian Independence Army activities and the fight for freedom. Kang Woo-kyu, who threw a bomb at the governor-General of Korea on September 2, 1919, can be cited as a leader who learned East Asian medicine. Kim Kwanje, who organized a secret organization by opening an East Asian medicine clinic in Gimhae, Gyeongsangnam-do, was involved in the struggle of the medical corps while working as a medical student. He is accused of providing a shelter by treating members of the Uiryeoldan. In 1919, the Manchurian Independence Army unit, which launched the March 1st Movement armed struggle, was established, and those who served as military doctors in various organizations can be found. Park Se-jung, who participated as an independent soldier at the age of 47, treated wounded soldiers and patients as a military doctor. A branch office was also created by raising military funds and participating in the Provisional Government of the Republic of Korea. Jang Hyong was able to raise independent military funds, campaign for the provisional government's independence petition, and lecture across the country mostly disguised as an East Asian medicine doctor, which led to several imprisonments for "fraud charges under the guise of similar medical practices".
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