• Title/Summary/Keyword: Mild Condition

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Morphologic Study of Renal Arteries in Rats Fed High-salt Diet (과량(過量)의 식염투여(食鹽投與)가 백서(白鼠)의 신동맥(腎動脈)의 형태학적(形態學的) 구조(構造)에 미치는 영향(影響)에 관(關)한 실험적(實驗的) 연구(硏究))

  • Choi, Won-Hee;Lee, Tae-Sook
    • Journal of Yeungnam Medical Science
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    • v.1 no.1
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    • pp.107-113
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    • 1984
  • To evaluate the morphologic changes of the renal arteries in the condition of high-salt diet, we scheduled the control group which fed routine animal diet added 0.06% of Sodium chloride, low-salt group which fed with 2.0% of sodium chloride, and high-Salt group which fed with 8.0% of sodium chloride. The experimental animals were sacrificed every two week until 20 weeks of final experimental week. The results obtained were as follows; 1. Slight intimal thickening of the renal arteries is observed from 16th experimental week and continued the end of the experiment in the rats of control group. 2. In low-salt group slight intimal thickening of the renal arteries is observed from 12th experimental week and continued to the end of the experiment. 3. In high-salt group the intimal thickening began from 6th experimental week and its degree was hasten with week, and provoked moderate to high degree of lesion at the end of the experiment. Medial proliferation and degeneration of the intima and media, though their quality is mild, also associated at the end of the experiment.

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Study on desorption efficiency of naphthalene by adsorbing media and desorbing solvent (흡착관과 탈착용매에 따른 나프탈렌의 탈착효율에 관한 연구)

  • Choi, Jin Hee;Jo, Jihoon;Choi, Seong Bong;Lee, Kwon Seob;Shin, Hyun Hwa;Yang, Jeong Sun
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.19 no.4
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    • pp.403-411
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    • 2009
  • This study was performed to propose appropriate conditions suited to the analysis of naphthalene by comparing desorption efficiencies under various conditions. 1. As to influence by adsorbing media and desorbing solvent on desorption efficiency of naphthalene, when adsorbed by CCT, o-xylene gave the highest desorption efficiency of $73.96{\pm}0.53%$ while the lowest of $1.14{\pm}0.03%$ desorbed by ether. Both XAD-2 and Chromosorb 106 showed around 90% of desorption efficiencies for each solvent, especially desorption efficiencies more than 95% were achieved when adsorbed by Chromosorb 106 and desorbed by $CS_2$ or o-xylene. 2. Desorption efficiencies descended over the storage period in any condition(p<0.05). For all three adsorbing media, while desorption efficiencies showed no significant difference(p>0.05) between room temperature and refrigeration a day of loading, samples kept in room temperature had higher desorption efficiencies than refrigerated ones in 7 and 14 days with significant difference(p<0.05).Also, desorption efficiencies dropped drastically in 7 days, from that point the decreasing tendency went mild. 3. When respective 1 TLV and 0.1 TLV of naphthalene were spiked on CCT and desorbed by CS2($46.45{\pm}0.59%$ vs. $30.15{\pm}0.81%$), o-xylene($73.96{\pm}0.53%$ vs. $67.51{\pm}1.34%$), and ether($1.14{\pm}0.03%$ vs. N.D.) desorption efficiencies increased as the amount of loading increased(p<0.05).On the other hand, naphthalene spiked on XAD-2 and Chromosorb 106 indicated no significant difference(p>0.05) in desorption efficiencies between 1 TLV and 0.1 TLV. In conclusion, in order for favorable desorption efficiencies of naphthalene it is important to select appropriate adsorbing media and desorbing solvent accordingly. The result revealed that adsorbing media of XAD-2 and Chromosorb 106 outperformed CCT and desorbing solvents of $CS_2$ and o-xylene achieved over 90% of desorption efficiencies when adsorbed on XAD-2 and Chromosorb 106. Also, considering the tendency that desorption efficiencies of naphthalene decrease with time, the samples should be analyzed as soon as possible.

Correlations between Symptoms of Sleep Apnea and Respiration during Sleep (수면 무호흡의 증상과 수면 호흡의 상관관계)

  • Lee, Sung-Hoon;Lee, Hee-Sang
    • Sleep Medicine and Psychophysiology
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    • v.1 no.2
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    • pp.163-171
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    • 1994
  • Objectives: Symptoms of sleep apnea consisted of insomnia, excessive sleepiness during daytime, impaired cognitive functions and emotional disturbances. It was not so well known how these symptoms are correlated with various parameters of sleep and respiration, and what kind of psychophysiological processes are involved in development of these symptoms. Methods: In sixty patients with sleep apnea, sleep and respiration were studied by polysomnography of one night, also symptoms of sleep apnea were evaluated with the scales of insomnia, daytime sleepiness, emotional disturbance and cognitive impairment We studied correlations between apnea symptoms, and various parameters of sleep and respiration such as sleep efficiency, number severity of apnea, $O_2$ desaturation and number of snoring. Results: The result showing significant correlations are as follows. The patients with better sleep in insomnia scale showed more number of apnea, particularly more central type, and much more snoring in stage 3 sleep and mild desaturation of $O_2$. Excessive sleepiness during daytime correlated significantly with stage 1 sleep and its snoring, but correlated negatively with stage 2 sleep. However, no significant correlation was found with degree of $O_2$ desaturation. Emotional disturbance was more apparent in the patients with severe $O_2$ desaturation and smaller amounts of stage 4 sleep. Cognitive function was more impaired in cases of more REM sleep and less apnea. Conclusions: Symptoms of sleep apnea may occur through different causes and processes. The evaluation of apnea symptoms may be helpful to understand in some degree the condition of sleep and respiration during sleep in clinical setting.

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The Effects of Endurance Training on the Hemogram of the Horse

  • Fan, Y.K.;Hsu, J.C.;Peh, H.C.;Tsang, C.L.;Cheng, S.P.;Chiu, S.C.;Ju, J.C.
    • Asian-Australasian Journal of Animal Sciences
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    • v.15 no.9
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    • pp.1348-1353
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    • 2002
  • The purpose of this study was to evaluate the changes and readjustment capacity in the hematological characteristics of the horse during and after a prolonged training program. One pony and two hot-blooded horses were used in this study. Resting or basal blood parameters were assessed by collecting blood samples of the animals for 1 to 2 months prior to start of the training program. Each animal was subjected to arbitrary exercise for 30 min by an automatic hot trotter and was bled at 0, 15, 30, 45 (15 min of recovery), 60 (30 min of recovery), and 75 min (45 min of recovery) after onset of exercise. All animals were exercised 3 times a week over a fivemonth period. Hematological parameters including average white blood cell counts (WBC, ${\times}$$10^3$/$\mu$l), erythrocyte concentrations (RBC, ${\times}$$10^6$/$\mu$l), hematocrit (HCT, %), mean corpuscular volume (MCV, fl), number of platelets (PLT, ${\times}$$10^4$/$\mu$l), hemoglobin concentration (Hb, g/dl), mean corpuscular hemoglobin (MCH, pg), and mean corpuscular hemoglobin concentration (MCHC, g/dl) were analyzed using an automatic cell counter. All animals showed that RBC, WBC, and HCT were significantly (p<0.05) increasing from 7.09, 8.55, and 43.5 to 8.11, 9.67, and 49.5, respectively, during the 30 min of exercise and were back to or lower than the initial basis (resting and 0 min) 30 min after exercise. However, no significant differences were detected in MCV (50.3-51.3 fl), MCH (17.2-17.4 pg), and MCHC (33.7-34.4 g/dl) values (p>0.05) regardless of the training periods. Similar trends were observed after 1, 3, 4, and 5 months of training when compared to the resting state. When these parameters were analyzed by the effect of training periods (month), mean WBC concentrations significantly reduced in the fourth and fifth month after onset of training compared to that in resting condition or the first month of training program (p<0.05). The RBC values elevated at the second month (9.40) and reaching a significantly low level (p<0.001) at the fifth month (8.62) after training compared to the first month of training (7.89). In conclusion, a mild training program enhances blood parameters gradually in both the horse and the pony. Therefore, an optimized training program is beneficial in promoting the endurance performance of the horse.

Design of waste Sludge/Food Waste Biological Treatment Process using Closed ATAD System (밀폐형 ATAD system을 이용한 하수슬러지/음식물쓰레기 통합처리 공정 설계)

  • Kwon, Hyeok-Young;Ji, Young-Hwan;Song, Han-Jo;Kim, Seong-Jung
    • Journal of the Korea Organic Resources Recycling Association
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    • v.8 no.4
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    • pp.129-137
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    • 2000
  • In this study, biological treatment process of MWWT(Municipal wet-waste Treatment) has been developed through a moduling of the containerized closed ATAD(Auto thermal aerobic digestion) system & closed vertical dynamic acerator, which were used for food waste and cattle manure, respectively. Though biological process has several advantages such as low concentrations of heavy metals and salts, proper and stable C/N ratio and constant reaction rate against the process treating two wastes separately, it has a obstacles of salt concentration and much usage of bulking agent such as wood chip. After rapid oxidation in the boxed tower reactor for 5 days, the content of sewage sludge would be reduced 65% on around, might be mixed with the food waste that had been treated in the static closed reactor during 6 days and put in the secondary static reactor for curing. During composting process, the odor contained in the gas generated from the reactor was removed by passing it through a biofilter as well as the leachate was treated in the wastewater treatment facility. Consequently, it seemed to be possible to compost sewage sludge at mild and stable operating condition and at low cost through the biological ATAD process resulting in the production of organic compost satisfying the specifications regulated by itself.

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Monitoring of white striping and wooden breast cases and impacts on quality of breast meat collected from commercial broilers (Gallus gallus)

  • Malila, Yuwares;U-chupaj, Juthawut;Srimarut, Yanee;Chaiwiwattrakul, Premsak;Uengwetwanit, Tanaporn;Arayamethakorn, Sopacha;Punyapornwithaya, Veerasak;Sansamur, Chalutwan;Kirschke, Catherine P.;Huang, Liping;Tepaamorndech, Surapun;Petracci, Massimiliano;Rungrassamee, Wanilada;Visessanguan, Wonnop
    • Asian-Australasian Journal of Animal Sciences
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    • v.31 no.11
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    • pp.1807-1817
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    • 2018
  • Objective: This study aimed at investigating white striping (WS) and wooden breast (WB) cases in breast meat collected from commercial broilers. Methods: A total of 183 breast samples were collected from male Ross 308 broilers slaughtered at the age of 6 weeks (n = 100) and 7 weeks (n = 83). The breasts were subjected to meat defect inspection, meat quality determination and histology evaluation. Results: Of 183, 4 breasts from 6-week-old broilers were classified as non-defective while the others exhibited the WS lesion. Among the 6-week-old birds, the defective samples from the medium size birds (carcass weight ${\leq}2.5kg$) showed mild to moderate WS degree with no altered meat quality. Some of the breasts from the 6-week-old birds with carcass weight above 2.5 kg exhibited WB in accompanied with the WS condition. Besides of a reduction of protein content, increases in collagen matter and pH values in the defective samples (p<0.05), no other impaired quality indices were detected within this group. All 7-week-old broilers yielded carcasses weighing above 2.5 kg and showed abnormal characteristics with progressive severity. The breasts affected with severe WS and WB showed the greatest cook loss, hardness, springiness and chewiness (p<0.05). Development of WB induced significantly increased drip loss in the samples (p<0.05). Histology indicated necrotic events in the defective myofibers. Based on logistic regression, increasing percent breast weight by one unit enhanced the chance of WS and WB development with advanced severity by 50.9% and 61.0%, respectively. Delayed slaughter age from 6 to 7 weeks increased the likelihood of obtaining increased WS severity by 56.3%. Conclusion: Cases of WS and WB defects in Southeast Asia have been revealed. Despite few cases of the severe WS and WB, such abnormal conditions significantly impaired technological properties and nutritional quality of broiler breasts.

TISSUE CHANGE AFTER EMBEDDING GELATIN MATRIX IMPLANT(FFIBREL®) IN SUBCUTANEOUS TISSUE OF RATS;HISTOLOGIC, IMMUNOHISTOCHEMICAL AND SCANNING ELECTRON MICROSCOPIC STUDY (백서의 피하조직에 Gelatin Matrix Implant (Fibrel®) 매식시 조직변화에 관한 연구)

  • Kim, Hong-Jin;Lee, Chong-Heon;Kim, Kyung-Wook
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.20 no.4
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    • pp.341-354
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    • 1998
  • GMI (Fibrel${(R)}$) is one of the dermal filling substances which have been successfully used for the treatment of depressed cutaneous scar and wrinkles. It's major components are; Gelatin powder, which provides a framework for the clot to form and remains stable under the scar, and ${\varepsilon}$-aminocaproic acid, which inhibits the production of fibrinolysin, and Plasma, which provides the necessary ingredients for collagen synthesis. GMI has advantages of low immunogenicity and increased longevity. It has been known to induce fibroblast activity and promote new collagen synthesis. We used 34 Sprague-Dawley rats which were bred under the same condition and duration. 18 of experimental animals were undergone cardiac puncture, and their blood were collected, centrifugated, and stored in freezer. Out of 16 animals, control group were injected with 2ml plasma into the subcutaneous tissue of Lt. scapular, while experimental group were implanted of 2 ml GMI into the Rt. same area. Experimental animals were sacrificed at the 3rd day, 5th day, 1st week and 2nd week respectively after implantation of GMI. To observe the histopathologic change of GMI and surrounding tissue reaction of GMI, we had examined with H&E staining, immunohistochemical staining with vimentin, ${\alpha}$-SMA, S-100 under LM and SEM. The obtained results were as follows ; 1. In LM study, the inflammatory cell infiltrations and granulation tissue formation were observed, and muscle tissues were well attached with adipose tissues in the control group. In the experimental group, inflammatory cell infiltrations had been observed by the 2nd week and irregular adipiose tissues and well differentiated mesenchymal tissues were examined. 2. In immunohistochemical study, the experimental group of ${\alpha}$-SMA study, there were a prominent positive response on endothelial development of granulation tissues and mesenchymal tissues compare with the control group. In vimentin study, positive response on mescenchymal fibroblast continued to 2nd week, but negative in the control group. In S-100 study, both groups were positively responded on irregular adipose tissues. 3. In SEM study, collagen fibers were embedded by the plasma by the 5th day in the control group, and in the 3rd day experiment GMI were resorved but communited with collagen fiber till the 1st week. Collagen fibers were infilt-rated into GMI at the 2nd week and the infilltrated GMI were conglomerated with the mature adipose cells and the collagen fibers. From the above results, GMI implantation in the subcutaneous tissue of Sprague-Dawley rat, the mild infiltration of inflammatory cells were showed till 2nd week and the granulation tissues were observed. GMI were nearly resorbed till 2nd week, but well attached with adipose tissue and collagen fibers. The endothelium and fibroblasts were actively proliferated. Adipose tissues and mesenchymal tissue cells were observed. As already expressed, GMI showed resorptive change in course of time without any early immune reaction, and seemed to induce fibroblast activity and promote new collagen synthesis.

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Varied Flow Analysis for Linear Drainage Channels (선형 배수로에 대한 부등류 해석)

  • Ku, Hye-Jin;Jun, Kyung-Soo
    • Journal of Korea Water Resources Association
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    • v.41 no.8
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    • pp.773-784
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    • 2008
  • The present study was carried out to examine flow properties in linear drainage channels such as road surface drainage facilities. The finite difference formulation for the varied flow analysis was solved for flow profiles in the channels. Starting the first step at the control section, the Newton-Raphson method was applied for producing numerical solutions of the equation. We considered two types of linear drainage channels, a channel with one outlet at downstream end and a channel with two outlets at both ends. Moreover, the flow analysis for various channel slopes was performed. However, we considered channels with the two outlets of slopes satisfying the condition that the both ends are the control section. The maximum of those slopes was decided from the relation between the channel slope and the location of control section. The flow of a channel with one outlet was calculated upward and downward from the control section existing in channel or upward from the control section at downstream end. The flow of a channel with two outlets at both ends were calculated for upstream and downstream channel segments divided by the water dividend, respectively and the flow analysis was completed when the water depth at the water dividend calculated from upstream end was equal to that calculated from downstream end. If the slope was larger than the critical slope, the channel with two outlets was likely to behave like the channel with one outlet. The maximum water depth was investigated and compared with that calculated additionally from the uniform flow analysis. The uniform flow analysis was likely to lead a excessive design of a drainage channel with mild slope.

Production of Fermentable Sugar from Lipid Extracted Algae using Hot Water Pretreatment (열수전처리를 이용한 탈지미세조류로부터 발효당 생산 공정 개발)

  • Lee, Jihyun;Shin, Seulgi;Choi, Kanghoon;Jo, Jaemin;Kim, JinWoo
    • Korean Chemical Engineering Research
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    • v.54 no.4
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    • pp.443-447
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    • 2016
  • The microalgae have cellulose as a main structural component of their cell wall and the lignin content in microalgae is much lower than other lignocellulosic biomass. Therefore, fermentable sugar production from microalgae (Tetraselmis KCTC 12236BP) can be carried out under pretreatment without high temperature and high pressure. It was investigated that the effect of hot-water pretreatment using sulfuric acid for lipid extracted algae which is expected to be a next generation biomass. The effects of three major variables including extraction temperature, acid concentration and time on the enzymatic hydrolysis were investigated. Among the tested variables, temperature and acid concentration showed significant effects and optimum pretreatment conditions for the economic operation criteria were obtained as follows: reaction temperature of $120^{\circ}C$, sulfuric acid concentration of 2 mol and pretreatment time of 40 min. Under the optimum conditions of acidic hot water pretreatment, experimentally obtained hydrolysis yield were 95.9% which showed about 2.1 fold higher compared with enzymatic hydrolysis process. Therefore, acid pretreatment under mild condition was proven to be an effective method for fermentable sugar production from lipid extracted microalgae.

A Study on Depressive disposition by Convergence approach of Leisure History and Family situation in Elderly Women (융복합적 접근을 통한 여성노인의 여가력, 가족상태에 따른 우울경향성 연구)

  • Choi, Hye-Jung;Back, Soon-Gi
    • Journal of the Korea Convergence Society
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    • v.6 no.5
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    • pp.295-302
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    • 2015
  • The purpose of this study is to convergence approach analyse the depression tendency by family situation and leisure history in the elderly who live in town house in Gyeonggi-do. This study analysed factors such as family situation, leisure history related to the depression tendency. This study selected 20 elderly people over 65 as research subjects and all data analysis was to conduct analyze by multi-variables independent t-test and one-way ANOVA. The results of GDS showed 11 people(55%) presented with mild depression tendency(M=13.0) and 1 person(5%) showed severe depression tendency. 11 out of 30 questions in GDS had a significant difference among the depression degree. Individual disease type had a significant difference in depression tendency statistically(F(3, 16)=4.534, p<.05). Past leisure satisfaction among total leisure history factors had a significant difference in depression tendency(F(2,17)=3.989, p<.05). The participants whose leisure activity was absent in the past and present showed a regressive depression tendency. Participants with no social companions also presented with the same. The study concluded to grasp the real condition of depression, and make practical alternatives for that, multilateral depression tendency analysis using diverse methods are necessary in the near future for improving reliability of tools.