• Journal of the Korean Home Economics Association
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• v.11 no.4
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• pp.414-423
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• 1973

Before the modern education was introduced in Korea men had the opportunity to be educated. Women's education was limited to a small number of girls belonging to ruling class. It was the men who got a job to earn the money for the family. The customary law prohibited women from being employed. They were to stay at home engaged in household affairs. This phenomenon has undergone a change when modern education was adopted which gave women the equal opportunity in education. The modernization of the country required a lot of educated and skilled labour. Since 1945 when Korea was liberated from the Japanese colonial administration the modernization programme has been worked out in every field such as industry, education, culture and politics, etc. The traditional grand family was transformed to nuclear family. The migration took place from country to town. With the adoption of compulsory education in the primary school the schoolgirls are increased in great number. The number of girls has been increased every year in Middle Schools, High schools and Universities. Even if boys still outnumber girls in all education institutions, the rate of increase of girl students are higher than that of boy students. Accordingly women are given more opportunity than ever for the employment vis-a-vis men. The number of employed women has been increasing greatly in recent years inproportion to the acceleration of industrialization. The type of their job is also various and colorful ranging from factory worker to doctor and lawyer. There are some problems to be solved with respect to the improvement of women's education. The improved women's education should be reviewed light of the fact that inequality still exists between men and women in occupation and wages, and that women is required of good education contributable to the better Korean society.

• Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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• v.6 no.7
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• pp.321-328
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• 2016

This study seeks the applicable value for contemporary multiculturalism based on the women (Hagar, Tamar, Rahab, Ruth, A great woman who lives in Shunem, A nameless servant girl) of the Old Testament who experienced migration. The article critiques uses of scripture that emphasize the roles of the women in the household. It provides a new interpretation through the perspective of feminist criticism, narrative criticism, and reader-response criticism. The article introduces the examples of six migrant women who created peace with people around them through their positive roles despite the fact that women had limited function under patriarchal society at that time. It suggests, while recognizing the difference regarding race, gender, and class between migrants and non-migrants, women and men, that they should not be used as the tools of discrimination. Furthermore, through these women from the Bible, the reader may find role models of independent women who are working for peace and social justice.

• Journal of Family Resource Management and Policy Review
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• v.16 no.4
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• pp.171-194
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• 2012

This study focuses on immigrant women who are married to Korean men and who live in a multicultural family situation in Gyeonggi-do. These women experience acculturative stress and marital conflict and this study aims to determine how social support seeks to mediate the effects of those stressors. The women in this study participated in activities and received services from one of Gyeonggi-do Province's civic organizations, religious organizations, or social service organizations, such as the Social Welfare Agency and the Multicultural Family Support Center. In order to verify the study's hypothesis, the researchers used the following statistical analytical methods : t-test, two-way ANOVA and multi-regression analysis. Analysis of the study's results showed that the highest degree of marital conflict was found in the sub-zones and variables that were personal. Those variable were : the difference in mindset and values (personal domain), economic problems (communal living area), a child's upbringing and education issues (third party area), and the participant's sex life (in the marital relationship). The hypothesis was tested using the research model validation and the results are summarized as follows. First, in order to analyze the relationship between the marriage migration females' acculturative stress and the impact of that stress on marriage conflict, the hierarchical regression analysis was used. It identified that a direct correlation existed between acculturative stress and marriage conflict; where a higher degree of acculturative stress was present, a higher degree of marriage conflict was found. Second, the study found a statistical significance in the correlation and relationship (${\beta}$=.208, p<0.05) between the acculturative stress of the marriage migration female and material support. In other words, the material support can be seen as having a moderating effect on the acculturative stress, which is the independent variable, and the marital conflict, which is the dependent variable.

• Genomics & Informatics
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• v.11 no.4
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• pp.224-229
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• 2013

Receptor for advanced glycation endproducts (RAGE) is a multi-ligand receptor that is able to bind several different ligands, including advanced glycation endproducts, high-mobility group protein (B)1 (HMGB1), S-100 calcium-binding protein, amyloid-${\beta}$-protein, Mac-1, and phosphatidylserine. Its interaction is engaged in critical cellular processes, such as inflammation, proliferation, apoptosis, autophagy, and migration, and dysregulation of RAGE and its ligands leads to the development of numerous human diseases. In this review, we summarize the signaling pathways regulated by RAGE and its ligands identified up to date and demonstrate the effects of hyper-activation of RAGE signals on human diseases, focused mainly on renal disorders. Finally, we propose that RAGE and its ligands are the potential targets for the diagnosis, monitoring, and treatment of numerous renal diseases.

• Annual Conference of KIPS
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• 2021.05a
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• pp.66-69
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• 2021

최근 실시간 응답 및 처리에 민감한 서비스들이 급증하면서 멀티액세스 엣지 컴퓨팅(MEC)이 차세대 기술로 주목받고 있다. 사용자들의 잦은 이동성 때문에 MEC 서버들 사이에서의 마이그레이션은 중요한 문제로 다뤄진다. 본 논문에서는 이동성이 많은 차량 엣지 컴퓨팅 환경을 고려하였으며, 강화학습 기법인 Q-learning 을 사용하여 마이그레이션 여부 및 대상을 결정하는 기법을 제안하였다. 제안 기법의 목적은 지연 제약조건을 만족시키면서 차량 엣지 컴퓨팅 서버(VECS) 사이의 로드 밸런싱을 최적화하는 것이다. 제안 기법의 성능 비교를 통하여 다른 기법들보다 로드 밸런싱 측면에서 약 22-30%, 지연 제약조건 만족도 측면에서 약 20-31%로 더 좋은 성능을 보임을 확인하였다.

• Annual Conference of KIPS
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• 2022.05a
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• pp.74-77
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• 2022

최근 사물 인터넷(IoT)의 발전으로 계산 집약적이거나 지연시간에 민감한 태스크가 증가하면서, 모바일 엣지 컴퓨팅 기술이 주목받고 있지만 지상에 고정되어 있는 MEC 서버는 사용자의 요구사항 변화에 따라 서버의 위치를 변경하거나 유연하게 대처할 수 없다. 이 문제를 해결하기 위해 UAV(Unmanned Aerial Vehicle)를 추가로 이용해 엣지 서비스를 제공하는 기법이 연구되고 있다. 그러나 UAV는 지상 MEC와는 달리 배터리 용량이 제한되어 있어 태스크 마이그레이션을 통해 에너지 사용량을 최소화하는 것이 필요하다. 본 논문에서는 MEC 서버들 사이의 로드 밸런싱과 UAV MEC 서버의 에너지 효율성을 최적화하기 위해 강화학습 기법인 Q-learning을 이용한 태스크 마이그레이션 기법을 제안한다. 제안 시스템의 성능을 평가하기 위해 UAV의 개수에 따라 실험을 진행하여 잔여 에너지와 로드 밸런싱 측면에서 성능을 분석한다.

• Biomolecules & Therapeutics
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• v.17 no.3
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• pp.288-292
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• 2009

Interactions between tumor cells and the extracellular matrix (ECM) strongly influence tumor development, affecting cell survival, proliferation and migration. Fibronectin, a major component of ECM, has been shown to interact with integrins especially the ${\alpha}5{\beta}1$ integrin. Cell invasion and metastasis are often associated with matrix metalloproteinases (MMPs) which are capable of digesting the different components of the ECM and basement membrane. MMP-2 is produced as a latent pro-MMP-2 (72 kDa) to be activated, resulting the 62 kDa active MMP-2. In this study, we investigated the effect of fibronectin on activation of pro-MMP-2 and the cellular invasiveness in H-Ras-transformed MCF10A human breast epithelial cells. Here we show that fibronectin induces activation of pro-MMP-2 and up-regulation of MT1-MMP and TIMP-2 in H-Ras MCF10A cells. These results demonstrate that H-Ras MCF10A cells secrete high levels of active MMP-2 when cultured with fibronectin, suggesting a possible interaction between the ECM network and H-Ras MCF10A cells to generate active MMP-2 which is important for proteolysis and ECM remodeling. Invasive and migratory abilities of H-Ras MCF10A cells were enhanced by fibronectin. Fibronectin up-regulated the expression of ${\beta}1$ integrin which may play a role in cellular responses exerted by fibronectin. Since acquisition of pro-MMP-2 activation can be associated with increased malignant progression, this study provides a mechanism for the cell surface-matrix degrading effect of fibronectin which will be crucial to breast cell invasion and migration.

• Journal of the Korean association of regional geographers
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• v.14 no.4
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• pp.347-366
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• 2008

With the advent of the global era in earnest, and with the transnational migration and exchanges of capital, goods and cultures being actively progressed at regional level, the importance of a region as the immediate stage for such migration and exchanges is brought into relief. This study aimed to analyze the multicultural policies being implemented by Goryeong gun county and draw out points and problems by focusing on immigrant women on marriage who are the main subjects of the discourse on multiculturalism in Korea. According to this research, the supports for the multicultural families in Goryeong-gun were provided mainly by Goryeong-gun Office and Goryeong Office of Education and many similar contents in supporting activities overlapped. However, the related agencies were not linked sufficiently, and there were little efforts made to improve the contents of the supporting activities. In order to recognize accurately the multicultural phenomena in a region and make appropriate response and support for them, the regional government wi]] have to become the center for the support of multiculturalism and implement an integration policy so that the resources and people within the region can be used in the right place.

• Molecules and Cells
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• v.37 no.1
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• pp.59-65
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• 2014

Eph receptors and their ligands ephrins have been implicated in guiding the directed migration of neural crest cells (NCCs). In this study, we found that Wnt1-Cre-mediated expression of ephrinA5-Fc along the dorsal midline of the dien- and mesencephalon resulted in severe craniofacial malformation of mouse embryo. Interestingly, expression of cephalic NCC markers decreased significantly in the frontonasal process and branchial arches 1 and 2, which are target areas for the migratory cephalic NCCs originating in the dien- and mesencephalon. In addition, these craniofacial tissues were much smaller in mutant embryos expressing ephrinA5-Fc. Importantly, EphA7-positive cephalic NCCs were absent along the dorsal dien- and mesencephalon of mutant embryos expressing ephrinA5-Fc, suggesting that the generation of cephalic NCCs is disrupted due to ephrinA5-Fc expression. NCC explant experiments suggested that ephrinA5-Fc perturbed survival of cephalic NCC precursors in the dorsal midline tissue rather than affecting their migratory capacity, which was consistent with our previous report that expression of ephrinA5-Fc in the dorsal midline is responsible for severe neuroepithelial cell apoptotic death. Taken together, our findings strongly suggest that expression of ephrinA5-Fc decreases a population of cephalic NCC precursors in the dorsal midline of the dien- and mesencephalon, thereby disrupting craniofacial development in the mouse embryos.

• BMB Reports
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• v.52 no.2
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• pp.139-144
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• 2019

Breast cancer (BRC) is the most invasive cancer in women. Although the survival rate of BRC is gradually increasing due to improved screening systems, development of novel therapeutic targets for inhibition of BRC proliferation, metastasis and recurrence have been constantly needed. Thus, in this study, we identified overexpression of SETDB1 (SET Domain Bifurcated 1), a histone methyltransferase, in RNA-seq data of BRC derived from TCGA portal. In Gene Ontology (GO) analysis, cell migration-related GO terms were enriched, and we confirmed down-regulation of cell migration/invasion and alteration of EMT /MET markers after knockdown of SETDB1. Moreover, gene network analysis showed that SMAD7 expression is regulated by SETDB1 levels, indicating that up-regulation of SMAD7 by SETDB1 knockdown inhibited BRC metastasis. Therefore, development of SETDB1 inhibitors and functional studies may help develop more effective clinical guidelines for BRC treatment.