• Title/Summary/Keyword: Migration Women

Search Result 142, Processing Time 0.034 seconds

Inhibition of Cell Migration by Corticotropin-Releasing Hormone (CRH) in Human Natural Killer Cell Line, NK-92MI (Corticotropin-Releasing Hormone (CRH)에 의한 인간 자연 살해 세포(NK-92MI)의 Migration 억제)

  • Cheon, So-Young;Bang, Sa-Ik;Cho, Dae-Ho
    • IMMUNE NETWORK
    • /
    • v.5 no.4
    • /
    • pp.247-251
    • /
    • 2005
  • Background: Natural killer (NK) cells are CD3 (-) CD14 (-) CD56 (+) lymphocytes. They play an important role in the body's innate immune response. They can induce spontaneous killing of cancer cells or virus-infected cells via the Fas/Fas ligand or the granzyme/perforin systems. The corticotropin-releasing hormone (CRH) is an important regulator for the body's stress response. It promotes proliferation and migration of various cancer cells through the CRH type 1 receptor under stress, and also inhibits NK or T cell activity. However, the relationship of CRH and NK cell migration to the target has not been confirmed. Herein, we study the effect of CRH on NK cell migration. Methods: We used the human NK cell line, NK-92MI, and tested the expression of CRH receptor type 1 on NK-92MI by RT-PCR. This was to examine the effect of CRH on tumor and NK cell migration, thus NK cells (NK-92MI) were incubated with or without CRH and then each CRH treated cell's migration ability compared to that of the CRH untreated group. Results: We confirmed that CRH receptor type 1 is expressed in NK-92MI. CRH can decrease NK cell migration in a time-/dose-dependent manner. Conclusion: These data suggest CRH can inhibit NK cell migration to target cells.

Theoretical Exploration of Migrant Women's Location as Multicultural Borderers: Conceptual Application of Borderlands, Intersectionality, and Transposition to the Feminist Migration Study (다문화경계인으로서 이주여성들의 위치성에 대한 이론적 탐색: '경계지대,' 억압의 '교차성,' '변위' 개념에 대한 검토 및 적용)

  • Jung, Hyunjoo
    • Journal of the Korean Geographical Society
    • /
    • v.50 no.3
    • /
    • pp.289-303
    • /
    • 2015
  • This paper is an introductory research to theorize women migrants' positionality in the era of globalization and the feminization of migration. It particularly examines three recent theoretical approaches within feminist studies and their application to the feminist migration study. Migration means a process of continuous negotiations of one's social and material positions within ever changing relations and situations through crossing various borders including national boundaries. Women migrants face multifaceted oppressions due to gendered relation and greater challenges to transform their identities. They embody politics of location through migration. The paper revolves around theories that explore a potential of feminist subjectivation of marginalized women such as female migrants through their identity negotiation and transformation. The theories in questions are Borderlands and the New Mestiza introduced by Gloria $Anzald{\acute{u}}a$, Intersectionality of oppressions, and Transpositions and the Nomadic Subjects by Rosi Braidotti who borrowed the theories of Deleuze and Guattari through feminist critiques. These theories all represent power relations and subject transformations through spatial metaphors. rough spatialized understandings, the paper proposes interlocking relations among space, gender and migration, and explores conceptual tools as well as epistemological insights for Korean migration study.

  • PDF

International Marriage Migrant Women in Korea (결혼 이주 여성의 현황과 문제: 새로운 여성간호 대상자의 출현)

  • Kim, Hyun-Sil
    • Women's Health Nursing
    • /
    • v.14 no.4
    • /
    • pp.248-256
    • /
    • 2008
  • Purpose: The findings of various studies and policy reports on marriage change, international marriage migrant women and its issues are presented in this study. Method: Research objectives were accomplished by conducting a literature review. The main areas of the literature review included married migrant women, its challenges, and current policies for international marriage migrant women. Result: Women migrating through international marriage are known to face various difficulties due to their migration. Some important obstacles women migrants face in the Republic of Korea are cultural differences in daily lifestyle, language, food, health care services, cultural assumptions, gender structure, family relationships, expected roles within family, interpersonal relationships and more. The plights of married migrant women include commercialization of international marriage, false information regarding the spouse, family abuse, insecure nationality, economic difficulty and unemployment, racial prejudice, and cultural maladjustment. Current support policies for migrant women living in Korea are suggested. Conclusion: This study concluded with policy implications and recommendations for future study. In addition, the author suggests the necessity of programs and policies for the improvement of married migrant women's well-being based on women's health and family nursing dimensions.

  • PDF

Transforming Growth Factor-${\beta}$ (TGF-${\beta}$) Induces Invasion and Migration of Ras- Transformed MCF10A Human Breast Epithelial Cells

  • Kim, Mi-Sung;Moon , A-Ree
    • Proceedings of the PSK Conference
    • /
    • 2002.10a
    • /
    • pp.327.3-328
    • /
    • 2002
  • Transforming growth factor-${\beta}$ (TGF-${\beta}$), a hormonally active polypeptide found in normal and transformed tissues. regulates cellular growth and phenotyphic plasticity. We have previously shown that H-ras. but not N-ras. induces invasive phenotype in MCF10A human breast epithelial cells. In this study. we wished to examine the effect of TGF-${\beta}$ on H-ras-induced invasion and motility in MCFI 10A cells by performing in vitro invasion assay and wound migration assay. (omitted)

  • PDF

Involvement of MAPKs in GDNF-induced Proliferation and Migration in Hs683 Glioma Cells

  • Song, Hyun;Moon, A-Ree
    • Proceedings of the PSK Conference
    • /
    • 2003.04a
    • /
    • pp.223.2-224
    • /
    • 2003
  • Glial cell-derived neurotrophic factor (GDNF) is a potent neurotrophic factor that enhances survival of midbrain doparminergic neuron. GDNF and its receptors are widely distributed in brain and are believed to be involved in the control of neuron survival and differentiation. GDNF increased proliferation and migration of Hs683 human giloma and C6 rat giloma cells in a dose-dependent manner. (omitted)

  • PDF

Vertical Migration and Horizontal Distribution of Chaoborus Larvae in Lake Fukami- ike, Japan

  • Nagano, Mariko;Tanaka, Masaaki;Yagi, Akihiko
    • Korean Journal of Ecology and Environment
    • /
    • v.38 no.spc
    • /
    • pp.27-30
    • /
    • 2005
  • Diel vertical migration (DVM) and horizontal distribution of Chaoborus flavicans larvae were studied in Lake Fukami-ike (maximum depth 7.75 m, Central Japan). The larvae showed a clear migration in the 4 ${\sim}$ 7 m layer during the day and throughout the water column at night. It should be noted that, while old instar distributed throughout the column during the night. Young instar was found only in the 1 ${\sim}$ 4 m layer. An examination of horizontal distribution revealed that larval stage was clearly related with the depth. It suggests that Chaoborus appear to exist in the deeper area during the larval stage.

GDNF Enhances Hs683 Human Glioma Cell Migration: Possible Involvement of MAPKs

  • Song , Hyun;Chung, Dong-June;Choung, Pill-Hoon;Moon , A-Ree
    • Proceedings of the PSK Conference
    • /
    • 2002.10a
    • /
    • pp.326.2-327
    • /
    • 2002
  • Glial cell-derived neurotrophic factor (GDNF) is a potent neurotrophic factor that enhances survival of midbrain doparminergic neuron. GDNF and its receptors are widely distributed in brain and are believed to be involved in the control of neuron survival and differentiation. In this study, we examined the effect of GDNF on proliferation and migration of Hs683 human glioma cells. GDNF markedly enhances proliferation and migration of Hs683 cells in a dose-dependent manner. (omitted)

  • PDF