• Title/Summary/Keyword: Micropump

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Development of an Implantable Drug Infusion Pump for Pain Control in Cancer Patients (암 환자 통증 조절을 위한 이식형 약물 주입 펌프 개발)

  • Bach, Du-Jin;Park, Jun-Woo;Hong, So-Young;Lee, Chul-Han;Kim, Kwang-Gi;Jo, Yung-Ho;Kim, Dae-Hyun
    • The KSFM Journal of Fluid Machinery
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    • v.12 no.3
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    • pp.31-37
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    • 2009
  • This paper presents a implantable intrathecal drug infusion pump for pain control in cancer patients. This device consists of micropump module, drug reservoir module and control module. The micropump module using cam-follower mechanism composed of small-sized four cams and four followers. Each followers is driven by a cam and liquid is discharged by a sequential reciprocal motion of the followers. The advantage of this structure is that it allows the pump to be clean and valveless. The drug reservoir module composed of drug chamber, gas chamber and diaphragm. The control module composed of battery, wireless communication unit and controller. To design a small-sized, low power pump some analysis were performed to determine the design parameters. To verify the feasibility of the experiment, a prototype was manufactured and its operating characteristics were investigated. Experimental results were in accordance with the expected results obtained from analysis.

Optimum Design of a Viscous-driven Micropump with Single Rotating Cylinder for Maximizing Efficiency (고효율을 위한 단일 실린더를 가진 점성구동 마이크로펌프의 최적설계)

  • Choi, Hyung-Il;Kim, Jong-Min;Choi, Dong-Hoon;Maeng, Joo-Sung
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.27 no.11
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    • pp.1889-1896
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    • 2003
  • In the microfluidic applications, viscous-driven pumping mechanism is a promising one since the viscous effect increases significantly as the size of device decreases, relative to the inertial effect. However, there exist a few drawbacks we have to improve such as low efficiency and small volume flow rate. In the present study, an optimum design synthesis is proposed to enhance the performance characteristics of the micropump with single rotating cylinder. First, the unstructured grid CFD method is described and validated by comparing its results to the previous results. Next, an automated optimum design synthesis tool is constructed by combining the aforementioned CFD analysis model with the mathematical optimization model. This technique is used to improve the performance characteristics of newly designed viscous-driven pump. The presented results show that the fluid dynamic optimization tool is robust and may be applied to other microfluidic device design applications.

Fabrications and Characteristics of Microfluidic Systems Actuated by Thermopneumatic Method (열공압 방식으로 구동되는 매세 유체 제어 시스템의 제작 및 특성)

  • Yoo Jong-Chul;Kang C. J.;Kim Yong-Sang
    • The Transactions of the Korean Institute of Electrical Engineers C
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    • v.55 no.2
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    • pp.88-92
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    • 2006
  • We present a microfluidic system with microvalves and a micropump that are easily integrated on the same substrate using the same fabrication process. The fabricated microfluidic system is suitable for use as a disposable device and its characteristics are optimized for use as a micro chemical analysis system (micro-TAS) and lab-on-a-chip. The system is realized by means of a polydimethylsiloxane (PDMS)-glass chip and an indium tin oxide (ITO) heater. We demonstrate the integration of the micropump and microvalves using a new thermopneumatic-actuated PDMS-based microfluidic system. A maximum pumping rate of about 730 nl/min is observed at. a duty ratio of 1 $\%$ and a frequency of 2 Hz with a fixed power of 500 mW. The measured power at flow cut-off is 500 mW for the microvalve whose channel width, depth and membrane thickness were 400 $\mu$m, 110 $\mu$m, and 320 $\mu$m, respectively.

An Experimental Study on the Pumping Characteristics of Diffuser-Nozzle Based Thermopneumatic Micropumps with Different Input Voltages and Frequencies (디퓨져와 노즐을 이용한 열공압형 마이크로 펌프의 입력 전압과 주파수에 따른 펌핑 특성에 관한 실험적 연구)

  • Jeong, Jin;Chae, Hee-Moon;Kim, Chang-Nyung
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.19 no.9
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    • pp.654-661
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    • 2007
  • This study has been conducted to investigate the pumping characteristics of diffuser-nozzle based thermopneumatic micropumps with different input voltages and frequencies. In this study, the displacements of the membrane have been obtained changing the input voltage and frequency in load-free state because it is very difficult to measure the displacement of the membrane in an actual load state. It has been found that the amplitude of the membrane displacement increases as the input voltage increases. The pressure head of the thermopneumatic micropump increases almost linearly over some range of the input voltage and decreases almost linearly as the frequency increases. Also, the results show that the thermopneumatic micropump can pump the fluid over a certain input voltage. This study can be utilized as basic data for design and evaluation of thermopneumatic micropumps.

NAVIER-STOKES SIMULATION OF A VISCOUS MICRO PUMP WITH A SPIRAL CHANNEL (스파이럴 채널을 가진 초소형 점성 펌프의 Navier-Stokes 해석)

  • Seo, J.H.;Kang, D.J.
    • Journal of computational fluids engineering
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    • v.16 no.1
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    • pp.90-95
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    • 2011
  • The Navier-Stokes equations are solved to study the flow characteristics of a micro viscous pump. The viscous micropump is consisted of a stationary disk with a spiral shaped channel and a rotating disk. A simple geometrical model for the tip clearance is proposed and validated by comparing computed flow rate with corresponding experimental data. Present numerical solutions show satisfactory agreement with the corresponding experimental data. The tip clearance effect is found to become significant as the rotational speed increases. As the pressure load increases, a reversed flow region is seen to form near the stationary disk. The height of the channel is shown to be optimized in terms of the flow rate for a given rotational speed and pressure load. The optimal height of the channel becomes small as the rotational speed decreases or the pressure load increases. The flow rate of the pump is found to be in proportion to the width of channel.

A Fabrication and Experiment of Induction-type EHD Micropump with Temperature Gradient (온도차를 이용한 유도형 마이크로 EHD 펌프의 제작 및 실험)

  • Youn, Yong-Kyu;Kim, Yong-Kweon
    • Proceedings of the KIEE Conference
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    • 1993.11a
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    • pp.198-200
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    • 1993
  • This paper represents the experimental results of electrohrdrodynamic(EHD) micropump driven by traveling- wave voltage. We fabricated 60 electrodes array with $100{\mu}m$ width and $100{\mu}m$ interval on the pyrex glass. On that glass we fabricated the micro channel which had the cross section of 3mm by 0.5mm. This pump was driven by 6 phase square traveling-wave voltage. We used the corn oil for experiments and increased the temperature of fluid by resistive heater. An optical microscope with CCD camera and monitor was used for observation. The fluid velocity was large for the large driving voltage and the high temperature. This EHD pump had the fluid velocity in specific frequency (near 1Hz) which had relation to the charge relaxation time in that oil.

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SIMULATION OF A MICROPUMP WITH STEP ELECTRODES (계단 모양 전극을 가진 미세펌프 해석)

  • Kim, Byoung-Jae;Lee, Seung-Hyun;Sung, Hyung-Jin
    • Journal of computational fluids engineering
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    • v.15 no.4
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    • pp.40-45
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    • 2010
  • The flow rate is higher in ACEO micro-pumps with step electrodes than in micro-pumps with planar asymmetric electrodes. In the present study, numerical simulations were made of a ACEO micro-pump with step electrodes to investigate the effects of electrode design parameters on the pumping flow rate. The electrical charge at the electrodes, the fluid flow, and potential were solved, taking into account the finite size of ions, that is, the steric effect. This effect is recognized to be capable of quantifying the electrical charge more accurately in the electrical double layer subject to high voltages. Geometrical parameters such as heights, widths, and gaps of three-dimensional electrodes were optimized to enhance the pumping flow rate. Moreover, the effect of amplitude and frequency of AC was studied.

Electrohydrodynamic Micropump Driven by Traveling Electric Fields

  • Park, Jin-Woo;Kim, Yong-Kweon
    • Journal of Electrical Engineering and information Science
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    • v.2 no.3
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    • pp.99-104
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    • 1997
  • A novel driving theory on the electrohydrodynamic (EHD) pump driven by traveling electric fields without the temperature gradient is proposed. The equations of the generating pressure and the flow rate are derived. The EHD micropump is fabricated by micromachining technology and tested. The channel heights are 50$\mu\textrm{m}$, 100$\mu\textrm{m}$ and 200$\mu\textrm{m}$ are respectively an the channel width is 3 mm. The spacing and width of the electrodes are both 40$\mu\textrm{m}$. The maximum pressure is 70.3 Pa, 35.4 Pa and 17.2 pa at he frequency of 0.2Hz for each channel height (50$\mu\textrm{m}$, 100$\mu\textrm{m}$ and 200$\mu\textrm{m}$) and the maximum flow rate is 0.90x10\ulcorner ${\mu}$$\ell$/min, 1.88x10\ulcorner ${\mu}$$\ell$/min and 4.85x10\ulcorner ${\mu}$$\ell$/min at the frequency of 0.4H for each channel height.

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Development of System For Cell Fusion Detection (세포 전기 융합 감지 장치에 관한 연구)

  • Kwon, Ki-Jin;Kim, Min-Soo;Park, Se-Kwang
    • Proceedings of the KIEE Conference
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    • 1994.07b
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    • pp.1336-1338
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    • 1994
  • Cell fusion device is an artificial equipment which fuses electrically two types of cells fed from the respective micropump to the fusion chamber by electric pulses. In this case, the detective sensor of flowing cell, along with passage, is required to control the time of pulses applied to cell and the injection of cells which are fed from inlet to micropump. There are two methods of detection of flowing cell; optical, impedance method. The difference of output for optical sensor is about 426mV for 805nm wavelength. about 37mV for 665nm wavelength. In impedance method, sensor output is 132.33mV at middle point and 117.10mV at edge point in the channel. Experimental results show that the optimal frequency range of sensor output is Iron 50Hz to 400Hz.

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Effect of Inlet and Outlet Position on the Pumping Characteristics of a Diffuser/Nozzle Based Piezoelectric Micropumps (디퓨저/노즐을 이용한 압전형 마이크로 펌프의 펌핑 특성에 미치는 입출구 위치의 영향)

  • Jang, Hun-Hee;Kim, Chang-Nyung;Jung, Jin
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.19 no.5
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    • pp.411-417
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    • 2007
  • This study has been conducted to investigate pumping characteristics of diffuser/nozzle based piezoelectric micropumps. The micropumps include a piezo disk (an actuator), a chamber and a set of diffuser and nozzle. Flow in the current micropumps is controlled by a set of diffuser and nozzle, not by a nap valve. The diffuser/nozzle based micropumps are more reliable in operation and are easier in manufacturing than the flap valve based micropumps. The flow rates of the piezoelectric micropumps have been closely analyzed with a numerical calculation. It has been found that the positions of the inlet and outlet of the micropump can influence the performance of the diffuser/nozzle based piezoelectric micropumps. This study may provide fundamental understanding for the design and analysis of the piezoelectric micropumps.