• Journal of the Korea Society of Computer and Information
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• v.29 no.3
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• pp.107-116
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• 2024

In this paper, we analyze the performance of MicroVM when running AI applications on an edge computing environment and whether it can replace current container technology and traditional virtual machines. To achieve this, we set up Docker container, Firecracker MicroVM and KVM virtual machine environments on a Raspberry Pi 4 and executed representative AI applications in each environment. We analyze the inference time, total CPU usage and trends over time and file I/O performance on each environment. The results show that there is no significant performance difference between MicroVM and container when running AI applications. Moreover, on average, a stable inference time over multiple trials was observed on MicroVM. Therefore, we can confirm that executing AI applications using MicroVM instead of container or heavy-weight virtual machine is suitable for an edge computing.

• BMB Reports
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• v.53 no.6
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• pp.291-298
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• 2020

Tumor angiogenesis is an essential process for growth and metastasis of cancer cells as it supplies tumors with oxygen and nutrients. During tumor angiogenesis, many pro-angiogenic factors are secreted by tumor cells to induce their own vascularization via activation of pre-existing host endothelium. However, accumulating evidence suggests that vasculogenic mimicry (VM) is a key alternative mechanism for tumor vascularization when tumors are faced with insufficient supply of oxygen and nutrients. VM is a tumor vascularization mechanism in which tumors create a blood supply system, in contrast to tumor angiogenesis mechanisms that depend on pre-existing host endothelium. VM is closely associated with tumor progression and poor prognosis in many cancers. Therefore, inhibition of VM may be a promising therapeutic strategy and may overcome the limitations of anti-angiogenesis therapy for cancer patients. In this review, we provide an overview of the current anti-angiogenic therapies for ovarian cancer and the current state of knowledge regarding the links between microRNAs and the VM process, with a focus on the mechanism that regulates associated signaling pathways in ovarian cancer. Moreover, we discuss the potential for VM as a therapeutic strategy against ovarian cancer.

• Journal of the Korean Ceramic Society
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• v.30 no.4
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• pp.289-298
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• 1993

Properties in terms of the variation of the glass compositions, which were density (p), molar volume(Vm), atom/ion packing density (Dp), refractive index (nD), transformation temperature (Tg), dilatometric softening point (Td), thermal expansion coefficient (α), Young's modulus (E), and knoop hardness (KHN) were investigated in CaO-SiO2 glasses and CaO-P2O5-SiO2 glasses containing less than 10mole% of P2O5. Those properties were measured by density measurement kit, Abbe refractometer, dilatometer, ultrasonic pulse echo equipment, and micro hardness tester. When CaO content was increased in CaO-SiO2 glasses, p, Dp, nD, Tg, Td, α, E and KHN were increased, while Vm was decreased. When P2O5 was added to the CaO-SiO2 glasses with constant CaO/SiO2 ratio as 1.07, p, Dp, nD, Tg, Td, α, E and KHN were decreased, while Vm was increased. When the amount of P2O5 in glasses was kept constant, the changes of the properties with variation of CaO content in the CaO-P2O5-SiO2 glasses were very similar to those of CaO-SiO2 glasses. These phenomena could be explained by the structural role of P2O5 in the CaO-P2O5-SiO2 glasses, which was polymerization of siicate structures and resulted in [PO4] monomer structure in glasses. Due to this structural characteristics, the bond strength and packing density were changed with compositions. Proportional relationships between 1) np and Dp, 2) Tg, Td, α and CaO content, 3) E and Vm-1, and 4) KHN and P2O5 content were evaluated in this investigation.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.26 no.3D
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• pp.409-416
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• 2006

Real-time traveler information disseminated through Variable Message Signs (VMS) is known to have effects on driver route choice decisions. In the past, many studies have attempted to optimize the system performance using VMS message content as the primary control variable of driver route choice. This research proposes a VMS information provision optimization model which searches the best combination of VMS message contents and display sequence to minimize the total travel time on a highway network considered. The driver route choice models under VMS information provision are developed using a stated preference (SP) survey data in order to realistically capture driver response behavior. The genetic algorithm (GA) is used to find the optimal VMS information provision strategies which consists of the VMS message contents and the sequence of message display. In the process of the GA module, the system performance is measured using micro traffic simulation. The experiment results highlight the capability of the proposed model to search the optimal solution in an efficient way. The results show that the traveler information conveyed via VMS can reduce the total travel time on a highway network. They also suggest that as the frequency of VMS message update gets shorter, a smaller number of VMS message contents performs better to reduce the total travel time, all other things being equal.

• Proceedings of the Korean Society of Computer Information Conference
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• 2011.01a
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• pp.191-194
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• 2011

본 연구에서는 Atmel사의 AVR 마이크로프로세서에 적합하게 개발된 Java 바이트코드 인터프리터인 NanoVM을 자체 개발한 마이크로로봇에 이식하여 Java 언어 전용 로봇을 구현하였다. 따라서 마이크로프로세서의 구조와 회로를 모르는 학생들도 로봇을 프로그래밍하면서 Java 언어를 효율적으로 학습할 수 있다. 더욱이 최근 학생들의 프로그래밍언어 학습 능력이 떨어지면서 컴퓨터 관련학과의 프로그래밍언어 교육이 많은 어려움을 겪고 있다. 따라서 학생들의 프로그래밍언어 학습 동기를 부여하고 창의 공학적 프로그래밍언어 교육프로그램의 도입이 필요한 시점에서 본 연구에서 개발한 Java 로봇은 많은 기여를 할 것으로 기대된다.

• BMB Reports
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• v.52 no.3
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• pp.214-219
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• 2019

The role of tumor-proximal factors in tumor plasticity during chemoresistance and metastasis following chemotherapy is well studied. However, the role of endothelial cell (EC) derived paracrine factors in tumor plasticity, their effect on chemotherapeutic outcome, and the mechanism by which these paracrine factors modulate the tumor microenvironment are not well understood. In this study, we report a novel mechanism by which endothelial miR-125a and let-7e-mediated regulation of interleukin-6 (IL-6) signaling can manipulate vasculogenic mimicry (VM) formation of MDA-MB-231 breast cancer cells. We found that endothelial IL-6 levels were significantly higher in response to cisplatin treatment, whereas levels of IL-6 upon cisplatin exposure remained unchanged in MDA-MB-231 breast cancer cells. We additionally found an inverse correlation between IL-6 and miR-125a/let-7e expression levels in cisplatin treated ECs. Interestingly, IL-6, IL-6 receptor (IL-6R), and signal transducer and activator of transcription 3 (STAT3) genes in the IL-6 pathway are closely regulated by miR-125a and let-7e, which directly target its 3' untranslated region. Functional analyses revealed that endothelial miR-125a and let-7e inhibit IL-6-induced adhesion of monocytes to ECs. Furthermore, conditioned medium from cisplatin treated ECs induced a significantly higher formation of VM in MDA-MB-231 breast cancer cells as compared to that from intact ECs; this effect of cisplatin treatment was abrogated by concurrent overexpression of miR-125a and let-7e. Overall, this study reveals a novel EC-tumor cell crosstalk mediated by the endothelial miR-125a/let-7e-IL-6 signaling axis, which might improve chemosensitivity and provide potential therapeutic targets for the treatment of cancer.

• Journal of Digital Contents Society
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• v.19 no.4
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• pp.809-814
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• 2018

With the proliferation of cloud computing infrastructures, service providers are able to deploy services in on-demand manner. Recently, microservice architecture has been attracting attention in order to maximize the efficiency of resource expansion in cloud infrastructure. Instead of implementing all of the service functions in a single software, service providers can easily and autonomously implement the necessary services by interconnecting the necessary services through an efficiently designed application programming interface (API). Moreover service developer can freely choice programming languages and define software, and functional structures to meet their functional requirements. In this paper, we propose virtual infrastructure manager service based on microservice architecture and evaluates its performance in scalability perspective.

• Journal of Satellite, Information and Communications
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• v.12 no.3
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• pp.108-113
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• 2017

The OBCP called 'operator on board' is that of a procedure to be executed on-board, which can be easily be loaded, executed, and also replaced, without modifying the remainder of the FSW. The use of OBCP enhances the on-board autonomy capabilities and increases the robustness to ground stations outages. The OBCP engine which is the core module of OBCP component in the FSW interprets and executes of the procedures based on script language written using a high-level language, possibly compiled, and it is relying on a virtual machine of the OBCP engine. FSW team in KARI has studied OBCP since 2010 as FSW team's internal projects, and made some OBCP engines such as Java KVM, RTCS/C and KKOMA on ERC32 processor target only for study. Recently we have been studying ESA's OBCP standard and implementing Lua and MicroPython on LEON2-FT/AT697F processor target as the OBCP engine. This paper presents the design and implementation of Lua for the OBCP engine on AT697F processor with VxWorks RTOS, and describes the evaluation result and performance of the OBCP engine.