• 한국정보통신학회논문지
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• 제18권12호
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• pp.2975-2981
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• 2014

기존 유선기반의 미소자기감지 시스템은 자기신호를 전기신호로 변환하여 신호처리부로 송신하는 과정에서 AC성 노이즈가 유입되고, 필터링 과정에서 과도한 신호의 시간 및 위상 지연 현상이 발생한다. 본 논문에서는 컨베어 이송장치에서의 무선통신 기술을 적용한 미소자기감지 시스템을 설계하고 구현한다. 무선미소자기시스템은 자기센서 검출부, 신호처리부, 무선센서네트워크부, 시스템 제어부 및 모니터링부로 구성하고, 무선 미소자기감지 시스템을 통해 밸브바디 내에 스틸볼이 삽입되어 있는 경우 자기센서 전압 값이 변화하는 것으로 감지하였다. 기존 유선기반의 시스템에 비해 검출 정확도 및 시간 지연 감소 등 성능이 향상됨을 평가를 통해 나타났으며, 패킷수신률 분석을 통해 미소자기시스템의 무선 적용 가능성을 확인하였다.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2014년도 춘계학술대회
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• pp.402-403
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• 2014

미소자기감지 시스템은 자기신호를 전기신호로 변환하여 신호처리부로 송신하는 과정에서 AC성 노이즈가 유입되고, 필터링 과정에서 과도한 신호의 시간 및 위상 지연 현상이 발생한다. 본 논문에서는 상기의 문제점을 해결하기 위하여 무선통신 기술을 적용한 미소자기 감지 시스템을 설계하고 구현하였다. 미소자기시스템은 자기 센서 검출부, 신호처리부, 무선센서네트워크부, 시스템 제어부 및 모니터링부로 구성하였으며, 무선센서네트워크 기반의 센서의 무선화 적용을 통해 신호 노이즈 및 신호 지연을 최소화 하는 결과를 얻을 수 있었다.

• 한국자기학회:학술대회 개요집
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• 한국자기학회 2015년도 임시총회 및 하계학술연구발표회
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• pp.161-163
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• 2015

The micro device, coil, and channel for the biosensor integrated with the GMR-SV device based on the antiferromagnetic IrMn layer was fabricated by the light lithography process. When RBCs coupled with several magnetic beads with a diameter of $1{\mu}m$ passed on the micro channel, the movement of RBC + ${\mu}Beads$ is controlled by the electrical AC input signal. The RBC + ${\mu}Beads$ having a micro-magnetic field captured above the GMR-SV device is changed as the output signals for detection status. From these results, the GMR-SV device having the width magnitude of a few micron size can be applied as the biosensor for the analysis of a new magnetic property as the membrane's deformation of RBC coupled to magnetic beads.

• 한국소성가공학회:학술대회논문집
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• 한국소성가공학회 2009년도 춘계학술대회 논문집
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• pp.68-69
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• 2009

Heat Assisted Magnetic Recording (HAMR) is one of the most promising candidates for high density magnetic storages over 1 Tb/$in^2$ areal density. Since the precise light delivery to the head is a key factor to realize HAMR application, it is required to establish the light delivery using micro laser module and micro actuator. For the careful control of micro actuator, a laser module was designed including laser diode, optical fiber, collimating lens, and fabricated V-groove substrate. In addition, the basic aligning method between the laser module and HAMR head was studied by the detection of current change in photo diode due to the amount of reflected light from the head.

• 한국자기학회지
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• 제25권1호
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• pp.16-21
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• 2015

광 리소그래피 공정을 이용하여 GMR-SV(Giant magnetoresistance-Spin valve) 다층박막 위에 마이크로 크기의 바이오센서용 소자와 코일-채널을 적층으로 각각 제작하였다. 직경 $1{\mu}m$ 크기인 여러 개의 자성비드가 결합된 적혈구가 마이크로 채널로 지나갈 때 코일에 인가하는 AC 신호로 정지 또는 통과하는 적혈구 움직임을 조절하였다. GMR-SV 소자 위에 포획된 적혈구-자성비드가 갖는 미세자기장은 자기저항비를 변화시켜 검출용 출력신호 특성으로 나타났다. 이것을 이용하여 자성비드를 결합한 적혈구의 막 변형에 따른 운동 특성을 분석하는 바이오센서로 활용할 수 있음을 보여주었다.

• KEPCO Journal on Electric Power and Energy
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• 제8권2호
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• pp.93-96
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• 2022

The boiler tubes of thermal power plants are exposed to harsh environment of high temperature and high pressure, and the deterioration state of materials rapidly increases. In particular, parent material and welds of the materials used are subjected to a temperature change and various constraints, resulting in deformation and its growth, resulting in frequent leakage accidents caused by tube failure. The power plant checks the integrity of boiler tubes through non-destructive testing as it may act as huge costs loss and limitation of power supply during power station shutdown period due to boiler tube leakage. However, the current non-destructive testing is extremely limited in the field to detect micro cracks. In this study, the ability of metal magnetic memory technique to detect flaws of size that are difficult to inspect by the visual or general non-destructive methods was verified in the early stage of their occurrence.

• 한국생물공학회:학술대회논문집
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• 한국생물공학회 2005년도 생물공학의 동향(XVI)
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• pp.19-19
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• 2005

This paper reports a novel magnetic force-based microfluidic immunoassay using microbeads and magnetic nanoparticles. The magnetic force-based immunoassay was devised first and successfully applied to detect the rabbit IgG as the model analyte of microfluidic sandwich immunoassay. The microchannels were fabricated by poly(dimethysiloxane) (PDMS) molding processes and bonded on a slide glass by plasma treatment. At the part of the inlet, sample solution was hydrodynamically focused. The focused microbeads of sample solution were flowed through the 150 ${\mu}m$ width channel of outlet. However, when the microbeads are conjugated with the superparamagnetic nanoparticles under the applied magnetic fields, they will switch their flow path and flow through the 95 ${\mu}m$ width channel of outlet. The movements of microbeads conjugated with magnetic nanoparticles were demonstrated by magnetic field $gradients.^{1)}$ High magnetic field gradients using micro electromagnets could be applied to this detection method for high sensitivity and lower detection limit. In addition, the multiplexed $immunoassay^{2)}$ using an encoded microbead which is immobilized with a certain antibody could be possible using this detection principle.

• 한국생물공학회:학술대회논문집
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• 한국생물공학회 2003년도 생물공학의 동향(XIII)
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• pp.717-720
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• 2003

A chromogenic biosensor employing microfluidics on a chip has been developed for the determination of high-density lipoprotein (HDL) cholesterol (HDL-C) in human serum. We have investigated a plain and effective method to immobilize enzymes within the microchip without chemically modifying micro-channel or technically micro-fabricating column reactor and fluid channel network. In assessing risk factors of coronary heart disease, a micro-chip system would minimize requirements of instrument and reagent handling.

• Tribology and Lubricants
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• 제11권5호
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• pp.128-135
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• 1995

Atomic force microscopy/friction force microscopy (AFM/FFM) techniques are increasingly used for tribological studies of engineering surfaces at scales, ranging from atomic and molecular to microscales. These techniques have been used to study surface roughness, adhesion, friction, scratching/wear, indentation, detection of material transfer, and boundary lubrication and for nanofabrication/nanomachining purposes. Micro/nanotribological studies of single-crystal silicon, natural diamond, magnetic media (magnetic tapes and disks) and magnetic heads have been conducted. Commonly measured roughness parameters are found to be scale dependent, requiring the need of scale-independent fractal parameters to characterize surface roughness. Measurements of atomic-scale friction of a freshly-cleaved highly-oriented pyrolytic graphite exhibited the same periodicity as that of corresponding topography. However, the peaks in friction and those in corresponding topography were displaced relative to each other. Variations in atomic-scale friction and the observed displacement has been explained by the variations in interatomic forces in the normal and lateral directions. Local variation in microscale friction is found to correspond to the local slope suggesting that a ratchet mechanism is responsible for this variation. Directionality in the friction is observed on both micro- and macro scales which results from the surface preparation and anisotropy in surface roughness. Microscale friction is generally found to be smaller than the macrofriction as there is less ploughing contribution in microscale measurements. Microscale friction is load dependent and friction values increase with an increase in the normal load approaching to the macrofriction at contact stresses higher than the hardness of the softer material. Wear rate for single-crystal silicon is approximately constant for various loads and test durations. However, for magnetic disks with a multilayered thin-film structure, the wear of the diamond like carbon overcoat is catastrophic. Breakdown of thin films can be detected with AFM. Evolution of the wear has also been studied using AFM. Wear is found to be initiated at nono scratches. AFM has been modified to obtain load-displacement curves and for nanoindentation hardness measurements with depth of indentation as low as 1 mm. Scratching and indentation on nanoscales are the powerful ways to screen for adhesion and resistance to deformation of ultrathin fdms. Detection of material transfer on a nanoscale is possible with AFM. Boundary lubrication studies and measurement of lubricant-film thichness with a lateral resolution on a nanoscale have been conducted using AFM. Self-assembled monolyers and chemically-bonded lubricant films with a mobile fraction are superior in wear resistance. Finally, AFM has also shown to be useful for nanofabrication/nanomachining. Friction and wear on micro-and nanoscales have been found to be generally smaller compared to that at macroscales. Therefore, micro/nanotribological studies may help def'me the regimes for ultra-low friction and near zero wear.

• Journal of Microbiology and Biotechnology
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• 제31권9호
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• pp.1323-1329
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• 2021

Micro-scale magnetic beads are widely used for isolation of proteins, DNA, and cells, leading to the development of in vitro diagnostics. Efficient isolation of target biomolecules is one of the keys to developing a simple and rapid point-of-care diagnostic. A zinc finger protein (ZFP) is a double-stranded (ds) DNA-binding domain, providing a useful scaffold for direct reading of the sequence information. Here, we utilized two engineered ZFPs (Stx2-268 and SEB-435) to detect the Shiga toxin (stx2) gene and the staphylococcal enterotoxin B (seb) gene present in foodborne pathogens, Escherichia coli O157 and Staphylococcus aureus, respectively. Engineered ZFPs are immobilized on a paramagnetic bead as a detection platform to efficiently isolate the target dsDNA-ZFP bound complex. The small paramagnetic beads provide a high surface area to volume ratio, allowing more ZFPs to be immobilized on the beads, which leads to increased target DNA detection. The fluorescence signal was measured upon ZFP binding to fluorophore-labeled target dsDNA. In this study, our system provided a detection limit of ≤ 60 fmol and demonstrated high specificity with multiplexing capability, suggesting a potential for development into a simple and reliable diagnostic for detecting multiple pathogens without target amplification.