• Title/Summary/Keyword: Micro-forming

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An Experimental Study on the Frost Prevention using Micro Liquid Film of an Antifreezing Solution (마이크로 부동액막을 이용한 착상방지에 관한 실험적 연구)

  • Chang Young- Soo;Yun Won -Nam
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.17 no.5
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    • pp.459-467
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    • 2005
  • The effect of anti freezing solution liquid film on the frost prevention is experimentally investigated. It is desirable that the antifreezing solution spreads widely on the heat exchanger surface forming thin liquid film to prevent frost nucleation and reduce the thermal resistance across the film. A porous layer coating technique is adopted to improve the wettedness of the anti freezing solution on a parallel plate heat exchanger. The antifreezing solution spreads widely on the heat exchanger surface with 100 $\mu$m thickness by the capillary force resulting from the porous structure. It is observed that the antifreezing solution liquid film prevents a parallel plate heat exchanger from frosting. The reductions of heat and mass transfer rate caused by thin liquid film are only $1\~2\%$ compared with those for non-liquid film surface.

MicroRNA-100 Resensitizes Resistant Chondrosarcoma Cells to Cisplatin through Direct Targeting of mTOR

  • Zhu, Zhe;Wang, Cun-Ping;Zhang, Yin-Feng;Nie, Lin
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.2
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    • pp.917-923
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    • 2014
  • Chondrosarcomas are malignant cartilage-forming tumors of bone which exhibit resistance to both chemotherapy and radiation treatment. miRNAs have been well demonstrated to regulate gene expression and play essential roles in a variety of biological processes, including proliferation, differentiation, migration, cell cycling and apoptosis. In this study, we obtained evidence that miR-100 acts as a tumor suppressor in human chondrosarcomas. Interestingly, cisplatin resistant chondrosarcoma cells exhibit decreased expression of miR-100 compared with parental cells. In addition, we identified mTOR as a direct target of miR-100. Overexpression of miR-100 complementary pairs to the 3' untranslated region (UTR) of mTOR, resulted in sensitization of cisplatin resistant cells to cisplatin. Moreover, recovery of the mTOR pathway by overexpression of S6K desensitized the chondrosarcoma cells to cisplatin, suggesting the miR-100-mediated sensitization to cisplatin dependent on inhibition of mTOR. In summary, the present studies highlight miR-100 as a tumor suppressor in chondrosarcoma contributing to anti-chemoresistance. Overexpression of miR-100 might be exploited as a therapeutic strategy along with cisplatin-based combined chemotherapy for the treatment of clinical chondrosarcoma patients.

A Study of Surface Improvement for Automotive Part by Injection Mold of Electronic Heating (전류가열 사출금형에 의한 자동차 부품의 표면개선에 관한 연구)

  • Choi, Dong-Hyuk;Hwang, Hyun-Tae;Son, Dong-Il;Kim, Daeil
    • Journal of the Korean institute of surface engineering
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    • v.51 no.1
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    • pp.40-46
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    • 2018
  • The light-weight of the research and development materials is actively carried out by overseas automobile companies and technology development continues in Korea. For the sake of fuel efficiency, the development of lightweight technology by improving the manufacturing method has been very effective. Recently, to maximize the effects of light weight, automotive interior parts have been applied by the micro-cellular injection molding using supercritical fluids and we call the Mucell manufacturing. This technique causes a problem in the quality of the surface of the products, because the shooting cells are revealed as the surface layer of the products by forming micro cells at the center of the products during injection molding. To overcome these phenomenon, we increased the temperature of injection molding using joule heating until critical value. In this study, we have predicted the problem of Mucell injection molding through the finite element analysis as changed the temperature by joule heating. From the result of finite element analysis, we have determined the optimized process and made the injection mold included electric current heating system with Mucell manufacturing analyzed the surface characteristics of the injection product according to changing mold temperature.

An Experimental Study on Freezing-Thawing and Mechanical Properties of Lightweight Foamed Concrete Using Micro Foaming Agent (기포제를 사용한 경량 콘크리트의 역학적 특성 및 동결융해 평가에 관한 실험적 연구)

  • Min, Tae-Beom;Woo, Young-Je;Lee, Han-Seung
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2009.11a
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    • pp.69-72
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    • 2009
  • This research is focused on the applying of the foaming agent which can make the independent pore in the concrete structure in order to make a lightweight concrete structure. This lightweight foamed concrete can satisfy both the required strength and the mechanical properties as structural members. In addition, anti freezing-thawing properties also required. As a result of the unit volume-weight measurement, when the foaming agent mixed at 0.5% to 1%, the lightweight foamed concrete can be applied for the structural member. Also the density and compressive strength measurement results reveals that it will be suitable as structural member with 21MPa strength, when the density is betweenity8 to 1.9 and foaming agent quantities are 0.5% to 1%. Finally the result of freezing-thawing experiment, the effect freezing-thawing damage reduced according to adding foaming agent because those foaming agent make micro-pores in the structure which are not seen in the ordinary concrete structure.

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A Study on Resin flow Analysis and Free Surface forming at Micro-stereolithography using a Dynamic Pattern Generator (동적 패턴 생성기를 이용한 마이크로 광 조형 시스템에서 수지 유동 해석 및 자유표면 형성에 관한 연구)

  • Won M.H.;Choi J.W.;Ha Y.M.;Lee S.H.;Kim H.C.
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2005.10a
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    • pp.878-881
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    • 2005
  • A Stereolithography technology is based on stacking of sliced layer from STL file that is converted from 3-dimensional CAD data. A microstereolithography technology is evolved from conventional stereolithography to fabricate microstructures. In this technology, we have to consider influence of resin flow to make refresh surface. To generate new resin surface, stage has to be moved downward deeply and upward to desired position. At this time, resin flow affects to refresh surface of resin. And resin viscosity is the key factor in simulation of resin flow. By setting optimal refresh time for resin surface, total fabrication time is reduced and there is no damage to fabricated layers. In this research, we simulate resin flow using CFD software and derive optimal stage moving time and dwelling time.

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Synthesis of LaMnO3-Diamond Composites and Their Photocatalytic Activity in the Degradation of Weak Acid Red C-3GN

  • Huang, Hao;Lu, Benqian;Liu, Yuanyuan;Wang, Xeuqian;Hu, Jie
    • Nano
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    • v.13 no.10
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    • pp.1850121.1-1850121.11
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    • 2018
  • In this study, a series of $LaMnO_3$-diamond composites with varied $LaMnO_3$ mass contents supported on micro-diamond have been synthesized using a sol-gel method. The as-prepared composites were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), Raman spectroscopy and the Fourier transform infrared spectra (FTIR). Meanwhile, the photocatalytic performances were also tested by photoluminescence (PL) spectroscopy, ultraviolet-visible diffuse reflection spectra (UV-Vis DRS) and the degradation of weak acid red C-3GN (RC-3GN). Results show that the peak position of $LaMnO_3$ is shifted to low angle after the introduction of diamond, and perovskite particles uniformly distributed on the surface of diamond, forming a network structure, which can increase the active sites and the absorption of dye molecules. When the mass ratio of $LaMnO_3$ and diamond is 1:2 (LMO-Dia-2), the composite shows the most excellent photocatalytic activity. This result offers a sample route to enlarge the range of the application of micro-diamond and provide a new carrier for perovskite photocatalysts.

Characteristics of Nano-structured SiO2:Zn Hollow Powders Prepared in the Micro Drop Fluidized Reactor (MDFR) Process (미세액적 유동반응기 공정에서 연속제조된 나노구조 SiO2:Zn 원환형 입자의 특성)

  • Yang, Si Woo;Kang, Yong;Kang, Ho
    • Korean Chemical Engineering Research
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    • v.56 no.4
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    • pp.585-591
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    • 2018
  • Characteristics of nano-structured $SiO_2:Zn$ hollow powders prepared in the micro drop fluidized reactor process were investigated with respect to bandgap energy and surface activity. The $SiO_2:Zn$ hollow powders were successfully prepared continuously in the one step process with reasonable production efficiency, with varying the amount of THAM (tris(hydroxymethyl)-aminomethane) additive and concentration of $Zn^{2+}$ ions. The doping of $Zn^{2+}$ ions into $SiO_2$ lattice led to the reduction of bandgap energy by forming the acceptor level of $Zn^{2+}$ below the conduction band of $Si^{4+}$ ions. The hollow shape also contributed to reduce the bandgap energy of $SiO_2:Zn$ powders. The doping of $Zn^{2+}$ ions into $SiO_2$ hollow powders could enhance the surface activity by forming SiO-H stretching and oxygen vacancies at the surface of $SiO_2:Zn$ powders.

The Influence of (Pd+Ag) Additions on the Glass Forming Ability of Zr-Al-Cu-Ni based Alloys (Zr-Al-Cu-Ni계 합금의 비정질형성능에 미치는 Pd과 Ag 복합첨가의 영향)

  • Kim, Mi-Hye;Lee, Byung-Woo;Kim, Sung-Gyu;Bae, Cha-Hurn;Jeong, Hae-Yong
    • Journal of Korea Foundry Society
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    • v.24 no.1
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    • pp.40-44
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    • 2004
  • The influence of Pd and Ag additions on the thermal stability, the glass forming ability (GFA) and mechanical property of $Zr_{55}Al_{10}Cu_{20}Ni_{10}Pb_{(5-x)}Ag_x$ (x = $0{\sim}5at%$) alloys obtained by melt spun and injection casting method have been investigated by using of X-ray diffraction, thermal analysis (DTA, DSC) and micro-Vickers hardness(Hv) testing. The thermal properties of melt-spun $Zr_{55}Al_{10}Cu_{20}Ni_{10}Pb_{(5-x)}Ag_x$ (x = $0{\sim}5at%$) alloys exhibit a supercooled liquid region(${\Delta}T_x$) exceeding 91 K before crystallization. The largest ${\Delta}T_x$ reaches as large as 126 K for the $Zr_{55}Al_{10}Cu_{20}Ni_{10}Pb_5$ alloy. The reduced glass transition temperature, $T_{rg}$ increased with increasing Ag content. The largest $T_{rg}$ is obtained for the $Zr_{55}Al_{10}Cu_{10}Ni_{10}Ag_5$ alloy. The $Zr_{55}Al_{10}Cu_{10}Ni_{10}Ag_5$ bulk amorphous alloy rod with 3 mm in diameter was fabricated by injection casting. Hv increased with increasing Ag content and the largest value was obtained for the $Zr_{55}Al_{10}Cu_{10}Ni_{10}Ag_5$ bulk amorphous alloy.

A Study on Plasma Display Panel Barrier Rib Fabrication by Mold and Electromagnetic Wave (몰드와 전자기파에 의한 PDP격벽의 성형에 관한 연구)

  • Son, Jae-Hyeok;Im, Yong-Gwan;Jeong, Yeong-Dae;Jeong, Seong-Il;Jeong, Hae-Do
    • Journal of the Korean Society for Precision Engineering
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    • v.19 no.6
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    • pp.176-183
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    • 2002
  • Plasma Display Panel(PDP) is a type of flat panel display utilizing the light emission produced by gas discharge. Barrier Ribs of PDP separating each sub-pixel prevents optical and electrical crosstalks from adjacent sub-pixels. The mold for forming the barrier ribs has been newly researched to overcome the disadvantages of conventional manufacturing processes such as screen printing, sand-blasting and photosensitive glass methods. The mold for PDP barrier ribs have stripes of micro grooves transferring glass-material wall. In this paper , Stripes of grooves of which width 48$\mu$m, depth 124$\mu$m , pitch 274$\mu$m was acquired by machining of single crystal silicon with dicing saw blade. Maximum roughness of the bottom of the grooves was 59.6 nm Ra in grooving Si. Barrier ribs were farmed with silicone rubber mold, which is transferred from grooved Si forming hard mold. Silicone rubber mold has the elasticity, which enable to accommodate the waviness of lower glass plate of PDP. The methods assisted by the microwave and UV was adopted for reducing the forming time of glass paste.

Investigation on the Size Effects of Polycrystalline Metallic Materials in Microscale Deformation Processes (미세성형 공정에서 다결정 금속재료의 크기효과에 관한 연구)

  • Kim, Hong-Seok;Lee, Yong-Sung
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.34 no.10
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    • pp.1463-1470
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    • 2010
  • Microforming, which exploits the advantages of metal forming technology, appears very promising in manufacturing microparts since it enables the production of parts using various materials at a high production rate, it has high material utilization efficiency, and it facilitates the production of parts with excellent mechanical properties. However, the conventional macroscale forming process cannot be simply scaled down to the micro-scale process on the basis of the extensive results and know-how on the macroscale process. This is because a so-called "size effect" occurs as the part size decreases to the microscale. In this paper, we attempt to develop an effective analytical and experimental modeling technique for explaining the effects of the grain size and the specimen size on the behavior of metals in microscale deformation processes. Copper sheet specimens of different thicknesses were prepared and heat-treated to obtain various grain sizes for the experiments. Tensile tests were conducted to investigate the influence of specimen thickness and grain size on the flow stress of the material. In addition, an analytical model was developed on the basis of phenomenological experimental findings to quantify the effects of the grain size and the specimen size on the flow stress of the material in microscale and macroscale forming.