• 대한본초학회지
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• 제32권6호
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• pp.63-69
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• 2017

Objectives : The purpose of this study is to investigate the preventive and therapeutic efficacy of osteoarthritis using a Yeonsan-Ogye egg. so, we researched at effects of Yeonsan-Ogye egg extract on MIA-induced Osteoarthritis animal models. Methods : Yeonsan-Ogye egg extract was administered 500 mg/kg/day, 1000 mg/kg/day and 2000 mg/kg/day to SD-Rat for 2 weeks. After that, osteoarthritis was induced with $60mg/m{\ell}$ of monosodium iodoacetate (MIA) and futher administration was continued for 4 weeks. 3D imaging of cartilage patella were obtained using a Micro-CT system and the pathology change of knee was observed by H&E and safranin-O staining. The weight bearing ratio was measured by incapacitance test meter. MMP-2, MMP-9, COMP, CTX II, calcitonin and glycosaminoglycan level in serum were measured using a ELISA. Results : Micro-CT and Histopathological analysis showed the volume of the patella cartilage and the proteoglycan contents were increased in all groups. also weight bearing ratio was decreased in all groups compared with control group. Calcitonin production was increased in and 2000 mg/kg/day group and glycosaminoglycan production was increased in all groups. In addition, MMP-2, MMP-9, COMP and CTX II production were decreased in 1000 and 2000 mg/kg/day groups respectively in comparison with control. Conclusions : The results for Yeonsan-Ogye egg showed prevention and treatment efficacy against arthritis at serum and the cartilage. These results may be used a remedy for new korea medicine to ease the symptoms mentioned above. also, suggest that Yeonsan-Ogye egg can be used preventive and therapeutic material for osteoarthritis.

• 한국임상수의학회지
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• 제34권6호
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• pp.454-458
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• 2017

A Maltese (case 1) and a Pomeranian (case 2) presented with acute right and left hind limb weight-bearing lameness. On physical examination, they exhibited severe pain and crepitus on the coxofemoral joint of affected hind limb. In addition, decreased thigh girth measurements were noted compared with the opposite leg. Radiological exam revealed necrotic areas in the femoral head of affected hind limb. These dogs were diagnosed with Legg-$Calv{\acute{e}}$-Perthes disease (LCPD). The dogs underwent micro total hip replacement (THR). After surgery, at 3 years (case 1) and 7 months (case 2), both dogs recovered normal activity. The thigh girth and lameness scores were apparently improved in the affected limbs of both dogs. No complications of prosthesis implants, such as loosening, were noted. The clinical outcomes of these cases indicate that dogs with LCPD can be successfully treated with micro THR and have a good prognosis immediately after surgery.

• 열처리공학회지
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• 제21권1호
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• pp.10-19
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• 2008

To investigate the effect of ultrasonic nano-crystalline surface modification (UNSM) treatment on rolling contact fatigue and residual stress properties of bearing steels, this paper carried out a rolling contact fatigue test, measured residual stress and retained austenite, performed a wear test, observed microstructure, measured micro hardness, and analyzed surface topology. After the UNSM treatment, it was found that the surface became minute by over $100{\mu}m$. The micro surface hardness was changed from Hv730~740 of base material to Hv850~880 with about 20% improvement, and hardening depth was about 1.3 mm. The compressive residual stress was measured as high as -700~-900 MPa, and the quantity of retained austenite was reduced to 27% from 34%. The polymet RCF-6 ball type rolling contact fatigue test showed over 4 times longer fatigue lifetime after the UNSM treatment under 551 kgf load and 8,000 rpm. In addition, this paper observed the samples, which went through the rolling contact fatigue test, with OM and SEM, and it was found that the samples had a spalling phenomenon (the race way is decentralized) after the UNSM treatment. However, before the treatment, the samples had excessive spalling and complete exploration. Comparison of the test samples before and after the UNSM treatment showed a big difference in the fatigue lifetime, which seems to result from the complicated effects of micro particles, compressive residual stress, retained austenite, and surface topology.

• Journal of Mechanical Science and Technology
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• 제20권1호
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• pp.51-58
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• 2006

To compensate for the motion errors in hydrostatic tables, a method to actively control the clearance of a bearing corresponding to the amount of error using actively controlled capillaries is introduced in this paper. The design method for an actively controlled capillary that considers the output rate of a piezo actuator and the amount of error that must be corrected is described. The basic characteristics of such a system were tested, such as the maximum controllable range of the error, micro-step response, and available dynamic bandwidth when the capillary was installed in a hydrostatic table. The tests demonstrated that the maximum controllable range was $2.4\;{\mu}m$, the resolution was 27 nm, and the frequency bandwidth was 5.5 Hz. Simultaneous compensation of the linear and angular motion errors using two actively controlled capillaries was also performed for a hydrostatic table driven by a ballscrew and a DC servomotor. An iterative compensation method was applied to improve the compensation characteristics. Experimental results showed that the linear and angular motion errors were improved to $0.12{\mu}m$ and 0.20 arcsec, which were about $1/15^{th}$ and $1/6^{th}$ of the initial motion errors, respectively. These results confirmed that the proposed compensation method improves the motion accuracy of hydrostatic tables very effectively.

• 한국생산제조학회지
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• 제22권4호
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• pp.747-754
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• 2013

This study introduces a recently designed desktop-sized NC turning system and its components. This machine is designed for the ultra-precise turning of parts with a diameter of 0.5-20 mm with minimum space usage for the machine. This study aims to achieve submicron-level accuracy of movements and good rigidity of the machine for precision machining using the desktop-sized machine. The components such as the main machine structure, air bearing servo spindle, and XZ stage with needle roller guides are designed, and the designed machine is built with a PC-based CNC controller. Its static and dynamic stiffness performances and positioning resolutions are tested. Through machining tests with single-crystal diamond tools, a form error less than $0.8{\mu}m$ and surface roughness (Ra) of $0.03{\mu}m$ for workpieces are obtained.

• 한국정밀공학회지
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• 제25권10호
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• pp.115-121
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• 2008

This paper presents bisymmetric dual iron core lineal motor stage for heavy-duty high precision applications such as large area micro-grooving machines or high precision roll die machines. In this stage, two iron core linear motors are installed in laterally symmetric way to cancel out the attractive forces. Main focus was given to analyzing the effect of cogging force and moment for two different layouts, which are symmetric and half-pitch shifted ones. Experimental results showed that the symmetric layout is more adequate for high precision applications because of its clear moment cancellation effect. It was also verified that the effect of the residual cogging moment can be suppressed further by increasing the bearing stiffness. One problem of the symmetric layout is added cogging force which hinders smooth motion, but its effect was relatively small compared with that of moment cancellation.

• Structural Engineering and Mechanics
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• 제55권2호
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• pp.315-334
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• 2015

This study's primary aim is to check the existence of a representative volume element for granular materials and determine the link between the properties (responses) of macro structures and the size of the discrete particle assembly used to represent a constitutive relation in a two-scale model. In our two-scale method the boundary value problem on the macro level was solved using finite element method, based on the Cosserat continuum; the macro stresses and modulus were obtained using a solution of discrete particle assemblies at certain element integration points. Meanwhile, discrete particle assemblies were solved using discrete element method under boundary conditions provided by the macro deformation. Our investigations focused largely on the size effects of the discrete particle assembly and the radius of the particle on macro properties, such as deformation stiffness, bearing capacity and the residual strength of the granular structure. According to the numerical results, we suggest fitting formulas linking the values of different macro properties (responses) and size of discrete particle assemblies. In addition, this study also concerns the configuration and displacement fluctuation of discrete particle assemblies on the micro level, accompanied with the evolution of bearing capacity and deformation on the macro level.

• 한방재활의학과학회지
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• 제24권2호
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• pp.65-81
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• 2014

Objectives This study was carried out to find out the anti-osteoarthritic effects of Mahwangbujaseshin- tang (Mahuangfuzixixintang ) on the monosodium iodoacetate (MIA)-induced osteoarthritis rats. Methods Osteoarthritis was induced by injecting MIA ($50{\mu}l$) into the knee joint of rats. Rats were divided into a 3 groups (n=7). The injection did not fit the normal group. A week later, after the injection of MIA, while control group took normal saline 2 ml, the extract of Mahwangbujaseshin-tang (Mahuangfuzixixintang ) (MBST) (200 mg/kg) was injected to treated group. After that, we examined hind paw weight bearing ability, functions of liver and kidney, serum TNF-$\alpha$, IL-$1{\beta}$, IL-6, $PGE_2$, $LTB_4$, TIMP-1, MMP-9 and hematology. Volume of cartilage was measured by micro CT arthrography. Injury of synovial tissue was measured by H & E, Safranin-O immunofluorescence. Results 1) DPPH and ABTS free radical scavenging activity of MBST was increased according to concentration of MBST and total phenolic contents were in high level. 2) In RAW 264.7 cells, ROS production was significantly decreased in MBST (at 10, $100{\mu}g/ml$) and NO was also decreased but meaningless in MBST (at $100{\mu}g/ml$). 3) In RAW 264.7 cells, IL-6 production was significantly decreased in MBST (at $100{\mu}g/ml$) and TNF-$\alpha$ and IL-$1{\beta}$ production were also decreased but meaningless in MBST (at $100{\mu}g/ml$). 4) In hind legs weight-bearing measurement, level of weight-bearing was increased. 5) Functions of liver and kidney were not affected. 6) TNF-$\alpha$, IL-$1{\beta}$, IL-6, $PGE_2$, $LTB_4$, MMP-9 and TIMP-1 production were significantly decreased. 7) In hematology, the levels of neutrophils, monocytes were significantly decreased and the levels of white blood cells, lymphocytes were also decreased but meaningless. 8) In micro CT-arthrography, cartilage volume was significantly increased. 9) Histopathologically, injury on cartilage and synovial membrane of MBST group was decreased. Conclusions Based on all results mentioned above, Mahwangbujaseshin-tang (Mahuangfuzixixintang) is believed to be meaningful for suppressing the progress of osteoarthritis. And it is related to inhibiting the activity of inflammatory cytokine and injury of volume in cartilage.

• 한국안전학회지
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• 제32권1호
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• pp.15-20
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• 2017

A large amount of research has been performed on the rolling contact fatigue(RCF) life of bearings, since it directly affects the safety and reliability of mechanical systems. It is well known that rolling contact fatigue life is influenced by several parameters including contact pressure, oil contamination by water or metal particles, and the surface conditions of bearings. However, the detailed damage mechanisms involved in rolling contact fatigue have not been clearly identified yet. In this paper the effects of water contamination of the lubricant and surface roughness of bearing steel on the rolling contact fatigue life were investigated. Two types of specimens with different surface roughness values were prepared through turning and lapping operations. They were tested under two different lubrication conditions, i.e. oil lubricant with 100% of oil and the water contaminated condition with 80% of oil and 20% of water using the rolling contact fatigue testing machine. The surface damage induced by the rolling contact fatigue was observed by using atomic force microscope(AFM). Experimental results show that the rolling contact fatigue life, $L_{10}$ was reduced by 24 to 33% depending on the lubrication condition. The reduction of fatigue life in the range of 53 to 57% was also observed at different surface roughness conditions.

• Tribology and Lubricants
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• 제36권4호
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• pp.193-198
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• 2020

Fluid film bearings are among the best devices used for overcoming friction and reducing wear. Surface texturing is a new surface treatment technique used for processing grooves and dimples on the lubricated surface, and it helps to minimize friction further and improve the wear resistance. In several studies, parallel surfaces, such as thrust bearings and mechanical face seals, have been investigated, but most sliding bearings have a convergent film shape. This paper presents the third part of a recent study and focuses on the effect of the groove shape on the lubrication performance of inclined slider bearings, following the two previous papers on the effects of the groove position and depth. We adopted the continuity and Navier - Stokes equations to conduct numerical analyses using FLUENT, which is a commercial computational fluid dynamics code. The groove shape adopted in the numerical analysis is rectangular and triangular, and its depth is varied. The results show that the streamlines, pressure distributions, and groove shape significantly influence the lubrication performance of the inclined slider bearing. For both shapes, the load-carrying capacity (LCC) is maximum near the groove depth, where vortices occur. In the shallow grooves, the LCC of the rectangular shape is higher, but in deeper grooves, that of the triangular shape is higher. The deeper the rectangular groove, the higher the decrease in the frictional force. The results of this study can be used as design data for various sliding bearings.