• Journal of Sensor Science and Technology
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• v.13 no.2
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• pp.85-89
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• 2004

This paper represents the development of high sensitivity photo-sensor for the fluorescence detection in the integrated biological analysis system. The finger-type PIN photodiodes were fabricated as the photo-sensor, and had a high sensitivity ($I_{light}/I_{dark}$ = 8720). The interference filter consisted of $TiO_{2}$ and $SiO_{2}$ was directly deposited on the photodiodes. Deposited filter with 95.5% reflection under 532 nm and 98% transmission over 580 nm exceedingly decreased the magnitude of background signal in the detection. The PDMS micro-fluidic channels are bonded on the photodiode by $O_{2}$ plasma treatment. The detection current was proportional to two primary parameters (light intensity, concentration), and the on-chip detection system could detect fluorescence signals down to 100 nM concentration (LOD = Limit of detection of rhodamine).

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2010.11a
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• pp.321-327
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• 2010

A simplified analytical modeling for micro-sized single metal particle combustion in air was conducted in the present study. The metal particle combustion consists of two distinct reaction regimes, ignition and quasi-steady burning, and the thermo-fluidic phenomena in each stage are formulated by virtue of the conservation and transport equations. Reliability of the model is shown by rigorous validation of the method with emphasis laid on the characterizing the commanding parameters. Effects of Initial particle size, initial oxide film thickness, convection, ambient pressure and temperature are examined and addressed with validation.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2011.04a
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• pp.341-350
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• 2011

A simplified analytical study for micro-sized single metal particle combustion in air was conducted in the present study. The metal particle combustion consists of two distinct reaction regimes, ignition and quasi-steady burning, and the thermo-fluidic phenomena in each stage are formulated by virtue of the conservation and transport equations. When particle temperature reaches to 1200 K, ended an ignition stage and was converted at quasi-steady combustion stage. Effects of Initial particle size, convection, ambient pressure and temperature are examined and addressed with validation.

• Journal of the Microelectronics and Packaging Society
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• v.17 no.4
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• pp.1-9
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• 2010

Three-dimensional (3-D) integration is an emerging technology, which vertically stacks and interconnects multiple materials, technologies, and functional components such as processor, memory, sensors, logic, analog, and power ICs into one stacked chip to form highly integrated micro-nano systems. Since CMOS device scaling has stalled, 3D integration technology allows extending Moore's law to ever high density, higher functionality, higher performance, and more diversed materials and devices to be integrated with lower cost. The potential benefits of 3D integration can vary depending on approach; increased multifunctionality, increased performance, increased data bandwidth, reduced power, small form factor, reduced packaging volume, increased yield and reliability, flexible heterogeneous integration, and reduced overall costs. It is expected that the semiconductor industry's paradiam will be shift to a new industry-fusing technology era that will offer tremendous global opportunities for expanded use of 3D based technologies in highly integrated systems. Anticipated applications start with memory, handheld devices, and high-performance computers and extend to high-density multifunctional heterogeneous integration of IT-NT-BT systems. This paper attempts to introduce new 3D integration technologies of the chip self-assembling stacking and 3D heterogeneous opto-electronics integration for realizng the super-chip.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.36 no.5
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• pp.545-551
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• 2012

We investigated the diffusive transport of bupivacaine HCl through the microchannels of microfluidic drug delivery devices. In the biodegradable microfluidic drug delivery devices developed in this research, the drug release rate can be controlled by simply modulating the geometrical parameters of the microchannels, such as the length, number, and cross-sectional area of the microchannels, when the microchannels are used as paths for drug release. However, the hydrophobic nature of a biodegradable polymer, 85/15 poly(lactic-co-glycolic acid), hinders the infiltration of a release medium (phosphate-buffered saline) through the microchannels into the reservoir of a device that contains bupivacaine HCl, at the early stage of drug release. This can have an adverse effect on the early stage release of local analgesic compounds from the device. In this study, microfluidic channels were surface-treated with surfactants such as PEG600 and Tween80, and the effects of the surfactants on the release performance are presented and analyzed.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.33 no.5
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• pp.331-338
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• 2020

In this study, the characteristic of a 3-D micro-woven material, which is one of the newly developed periodic open-cell structure, is analyzed through various computational simulations. To increase the accuracy of the numerical simulations, the distance between each directional wire is parameterized using six design variables, and its model geometry is precisely discretized using tetrahedron elements. Using the improved computational model, the material properties of the mechanical, thermal, and fluidic behavior are investigated using commercial software and compared with the previous experimental results. By changing the space between the x- and y-directional wires, a parametric test is performed to determine the tendency of the change in the material properties. In addition, the correlation between two different material properties is investigated using the Ashby chart. The result can further be used in determining the optimal pattern and wire spacing in 3-D micro-woven materials.

• Journal of the Korean Society for Precision Engineering
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• v.29 no.2
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• pp.214-221
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• 2012

Recently, the biochip which is a prime representation of NT, IT, BT, as an example of convergence technology, has been frequently mentioned. With the recent rapid advance in biotechnology, these compact devices, such as lab-on-a-chip or u-TAS, have been developed, and more research is needed. These compact devices typically use the micro-channel in order to shed or detach and mix a variety of materials. Specially, in micro-fluidic systems, a mixer is necessary to produce a mixture because only laminar flow occurs at a low-Reynolds number. To solve this problem, HVM a micromixer that induces a horizontal and vertical multi-mixing flow motion, is proposed. The mixing performance was analyzed and verified by optimizing the shape through the CFD analysis and evaluating the structural analysis and the soundness with material properties that are obtained through the basic experiment.

• Journal of Welding and Joining
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• v.35 no.2
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• pp.58-62
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• 2017

A319 aluminum alloy containing 6.5% Si and 3.5% Cu as major alloying elements has been widely used in machinery parts because of its excellent castability and crack resistance. However it needs more wear resistance to extend its usage to the severe wear environments. It has been known that hyper-eutectic Al-Si alloy having more than 12.6% Si contains pro-eutectic Si particles, which give better wear resistance and lubrication characteristics than hypo-eutectic Al-Si alloy like A319 alloy. In this study, it was tried to clad hyper-eutectic Al-Si alloy on the surface of A319 alloy. In the experiments, Al-36%Si alloy powder was mixed with organic binder to make a fluidic paste. The paste was screen-printed on the A319 alloy surface, melted by pulsed Nd:YAG laser and alloyed with the A319 base alloy. As experimental parameters, the average laser power was changed to 111 W, 202 W and 280 W. With increasing the average laser power, the melting depth was changed to $142{\mu}m$, $205{\mu}m$ and $245{\mu}m$, and the dilution rate to 67.2 %, 72.4 % and 75.7 %, and the Si content in the cladding layer to 16.2 %, 14.6 % and 13.7 %, respectively. The cross-section of the cladding layer showed very fine eutectic microstructure even though it was hyper-eutectic Al-Si alloy. This seems to be due to the rapid solidification of the melted spot by single laser pulse. The average hardness for the three cladding layers was HV175, which was much higher than HV96 of A319 base alloy. From the block-on-roll wear tests, A319 alloy had a wear loss of 5.8 mg, but the three cladding layers had an average wear loss of 3.5 mg, which meant that an increase of 40 % in wear resistance was obtained by laser cladding.

• Journal of Sensor Science and Technology
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• v.17 no.5
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• pp.369-374
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• 2008

A novel fiber optic surface plasmon resonance (SPR) sensor using cyclic olefin copolymer (COC) prism with the spectral modulation is presented. The SPR sensor chip is fabricated using the SU-8 photolithography, Ni-electroplating and COC injection molding process. The sidewall of the COC prism is partially deposited with Au/Cr (45/2.nm thickness) by e-beam evaporator, and the thermal bonding process is conducted for micro fluidic channels and optical fibers alignment. The SPR spectrum for a phosphate buffered saline (0.1.M PBS, pH.7.2) solution shows a distinctive dip at 1300.nm wavelength, which shifts toward longer wavelength with respect to the bovine serum albumin (BSA)concentrations. The sensitivity of the wavelength shift is $1.16\;nm{\cdot}{\mu}g^{-1}{\cdot}{\mu}l^{-1}$. From the wavelength of SPR dips, the refractive indices (RI) of the BSA solutions can be theoretically calculated using Kretchmann configuration, and the change rate of the RI was found to be $2.3{\times}10^{-5}RI{\cdot}{\mu}g^{-1}{\cdot}l^{-1}$. The realized fiber optic SPR sensor with a COC prism has clearly shown the feasibility of a new disposable, low cost and miniaturized SPR biosensor for biochemical molecular analyses.

• Korean Chemical Engineering Research
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• v.57 no.5
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• pp.730-734
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• 2019

Thermophoresis is a transport phenomenon of particles driven by a temperature gradient of a medium. In this paper, we discuss the thermophoresis of particles in microfluidic channels. In a non-fluidic, stagnant channel, the thermophoretic transport of micro-particles was found to be larger in proportion to the voltage applied to the platinum wire heat source installed in the channel. The variation of the temperature around the platinum wire depending on the voltage was estimated, by using the Callendar-van Dusen equation. The thermophoretic behavior of nano-particles in the same system was observed, which is similar to that of the microparticles. Finally, we fabricated a Y-shaped microfluidic channel with a platinum wire heat source installed in the channel, to realize the thermophoretic phenomenon of the particles in the suspension flowing through the channel. It is shown that the flow of the suspension can be controlled based on the thermophoretic principle.