• Title/Summary/Keyword: Micro pump

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The Effects of Leukocyte Depleted Priming Solution on the Gastric Mucosal $Co_{2}$ Partial Pressure and Serum IL-8 Level during Cardiopulmonary Bypass in Korean Mongrel Dogs (한국산 잡견에서 백혈구 제거 충진액이 체외순환 중 위점막 이산화탄소 농도와 IL-8 수준에 미치는 영향)

  • Park Kuhn;Lee Jong Ho;Kim Jin Ho;Jin Ung;Kwon Jong Bum;Kim Chi Kyeong;Wang Young Pil
    • Journal of Chest Surgery
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    • v.38 no.12 s.257
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    • pp.807-814
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    • 2005
  • Background: Cardiopulmonary bypass is an essential process to maintain circulation for saving life during the cardiac surgery, But it is a process in which systemic inflammation was evoked inevitably because of the exposure of blood to foreign surface. The injuries to distal organs during the cardiopulmonary bypass were resulted from systemic inflammation and the disturbances of micro-circulations in the organs. We designed this study to research the effects of leukocyte depletion from pump-oxygenator priming solution on the systemic inflammation, and the micro-circulation of gastric mucosa that is suggested by the gastric mucosal $CO_{2}$ partial pressure and acidity. Material and Method: The dogs were divided into three groups according to the different pump-oxygenator priming solutions; non-hemic crystalloid solution; leukocyte-depleted homologous blood; and non leukocyte-depleted homo-logous blood. Each priming solution group contained five dogs. In all three groups, 2 hours of cardiopulmonary bypass, and 4 consecutive hours of general anesthesia was maintained on the mechanical ventilation. Each dog was evaluated for the gastric mucosal pH, $CO_{2}$ partial Pressure, arterial pH, $CO_{2}$ partial pressure, the exhaled air $CO_{2}$ partial pressure and the level of IL-8 on before the cardiopulmonary bypass, 1 hour after the cardiopulmonary bypass, 2 hours after the cardiopulmonary bypass, 2 hours after the restoration of normal circulation, and 4 hours after the restoration of normal circulation after the cardiopulmonary bypass. The levels of IL-8 were measured with ELISA (enzyme linked immunosorbent assay) technique. Result: 1. There were significant differences of gastric mucosal $CO_{2}$ partial pressure between the leukocyte-depleted homologous blood group and other two groups(vs non leukocyte-depleted homologous blood group; P=0.02, vs non-hemic crystalloid solution group; P=0,01). 2. The gastric mucosal pH of leukocyte-depleted homologous blood group was significantly different from non leukocyte-depleted homologous blood group (p=0.01). 3. The levels of IL-8, which examine the systemic inflammation, showed signi- ficantly better results in leukocyte-depleted homologous blood group and non-hemic crystalloid solution group than non leukocyte-depleted homologous blood group (p=0.01, 0.01). Conclusion: Based upon these results, we concluded that the leukocyte depletion from the pump-oxygenator priming solution has a beneficial effects in reducing systemic inflammation and the preserving of gastric mucosal micro-circulation.

The Development of Hemodialysis System Based on Embedded System (임베디드 시스템 기반의 혈액 투석기 시스템의 개발)

  • Ji, Jung-Ho;Lee, Kyoung-Joung;Kim, Young-Ho;Park, Kwang-Li
    • The Transactions of the Korean Institute of Electrical Engineers D
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    • v.51 no.11
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    • pp.521-527
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    • 2002
  • The Hemodialysis system is the device for the patients who have suffered from end stage renal failure as the kidney which removes the waste products in a human body. The existing hemodialysis is based on a 8-bit micro-controller and it is not a touch-screen type but a manual type. This paper is focused on hemodialysis system based on high control and expension embedded system. The whole system consists of main control unit and sub control unit(dialysis control unit, blood control unit, monitoring control unit, networking unit). The dialysis control unit, blood control unit, monitoring control unit are processed by 3 microcontrollers and network unit is for monitoring a renal failure patient's condition. For the evaluation of the system performance, the saline was pured into blood unit and then water removal rate, conductivity and temperature of hemodialysis liquid were measured 10 times in an each state suing the UF pump in the fluid unit varing the quantity of saline to 1000cc, 2000cc, 3000cc and 4000cc. As a result, the rates of water removal are 98.6% in condition of 000cc saline, 96.9% in 2000cc, 98.9% in 3000cc and 98.3% in 4000cc. The conductivities of hemodialysis liquid are 99.6% in the first to third condition and 99.7% in the forth condition. The temperatures of hemodialysis liquid are 99.8% in the first to third condition and 99.6% in th forth condition.

Performance Evaluation of Backwash Hydrodynamic Separator Filter for Treatment of Micro Particles (역세척 Hydrodynamic Separator Filter를 이용한 미세입자 제거 특성 분석)

  • Lee, Jun-Ho;Bang, Ki-Woong
    • Journal of Korean Society of Environmental Engineers
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    • v.34 no.10
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    • pp.694-701
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    • 2012
  • The main purpose of this study is to evaluate of backwash system of hydrodynamic separator filter (HSF) with solar powered submerged pumps. It consists of a photovoltaic solar array, control electronics, battery, and two submersible pump powered by a 12 voltage DC motor. The laboratory scale study on treatable potential of micro particles using backwash HSF that was a combined with perlite filter cartridge and backwash nozzles. Since it was not easy to use actual storm water in the scaled-down hydraulic model investigations, it was necessary to reproduce ranges of particle sizes with synthetic materials. The synthesized storm runoff was made with water and addition of particles; ion exchange resin partices, silica gel particles, and commercial area manhole sediment particles. HSF was made of acryl resin with 250 mm of diameter filter chamber and overall height of 800 mm. Four case test were performed with different backwashing conditions and determined the SS removal efficiency with various surface loading rates. The operated range of surface loading rate was about 308~$1,250m^3/m^2/day$. It was found that SS removal efficiency of HSF using two submersible pumps improved by about 18% compared with HSF without backwash. Nonpoint control devices with solar water pumping systems would be useful for backwashing the filter in areas with not suppling electricity and reduce filter media exchange cost.

A Micro Solar Energy Harvesting Circuit with MPPT Control (MPPT 제어기능을 갖는 마이크로 빛에너지 하베스팅 회로)

  • Yoon, Eun-Jung;Park, Jong-Tae;Yu, Chong-Gun
    • Journal of the Institute of Electronics and Information Engineers
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    • v.50 no.6
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    • pp.105-113
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    • 2013
  • In this paper a micro solar energy harvesting system with MPPT(Maximum Power Point Tracking) control using a miniature PV(photovoltaic) cell of which the output is less than 0.5V is proposed. The MPPT control is implemented using linear relationship between the open-circuit voltage of a PV cell and its MPP(Maximum Power Point) voltage such that a pilot PV cell can track the MPP of the main PV cell in real time. The proposed circuit is designed in 0.18um CMOS process. The designed chip area is $900um{\times}1370um$ including a load charge pump and pads. Measured results show that the designed system can track the MPP voltage changes with variations of light intensity. The designed circuit with MPPT control delivers MPP voltages to load even though the load is heavy such that it can supply more power when the MPPT control is applied. The proposed circuit does not require any precharged battery resulting in more suitability for miniaturized self-powered systems compared to the existing works.

Encapsulation of Agro-Probiotics for Promoting Viable Cell Activity (생균력 증진을 위한 농업용 미생물제 미세캡슐화)

  • Choi, So-Young;Yoon, Min-Ho;Whang, Kyung-Sook
    • Korean Journal of Soil Science and Fertilizer
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    • v.38 no.5
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    • pp.287-293
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    • 2005
  • In this work, to develop soil inoculant which maintains stable viable cells and normalized quality, studies on micro-encapsulation with bacteria and yeast cells were performed by investigating materials and methods for micro-encapsulation as well as variation and stability of encapsulated cells. Preparation of capsule was conducted by application of extrusion system using micro-nozzle and peristaltic pump. K-carragenan and Na-alginate were selected as best carrier for gelation among K-carageenan, Na-alginate, locust bean gum, cellulose acetate phthalate (CAP), chitosan and gelatin tested. Comparing the gels prepared with Bacillus sp. KSIA-9 and carriers of 1.5% concentration, although viable cell of K-carragenan and Na-alginate was six times higher than those of other, Na-alginate was finally selected as carrier for gelation because it is seven times cheaper than K-carragenan. The gel of 1.5% Na-alginate was also observed to have the best morphology with circular hardness polymatrix and highest viable cell. When investigating the stability of encapsulated cells and the stabilizer effect, free cells were almost dead within 30 or 40 days whereas encapsulated cells decreased in 10% after 30 days and 15-30% even after 120 days. As stabilizer for maintaining viable cell, both 1% starch and zeolite appeared to possess the level of 70-80% cell for bacteria and yeast until after 120 days.

Experimental Study on Millimeter Scale Two Phase Catalytic Reactor (밀리미터 스케일의 이상 분해 반응기에 대한 실험적 연구)

  • Cho, Chung-Hun;Lee, Dae-Hoon;Kwon, Se-JIn
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.28 no.3
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    • pp.265-270
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    • 2004
  • Experiment study on a down scaled two-phase catalytic reactor is presented. As a preliminary step for the development of catalytic reactor, nano-particulate catalyst was prepared. Perovskite La$\_$0.8/Sr$\_$0.2/CoO$_3$is chosen and synthesized as a catalyst considering superior catalytic performance in reduction and oxidation process where oxygen is involved among the reagent. Reactor that has a scale of 2${\times}$10${\times}$25mm was made by machining of A1 block as a layered structure considering further extension to micro-machining. Hydrogen peroxide of 70wt% was adopted as reactant and was provided to the reactor loaded with 1.5 g of catalyst. Reactant flow rate was varied by precision pump with a range of 0.15cc/min to 17.2cc/min. Temperature distribution within reactor was recorded by 3 thermocouples and total amount of liquid product was measured. Temperature distribution and factors that affect temperature were observed and relation between temperature distribution and production rate was also analyzed. Relative time scale plays a significant role in the performance of the reactor. To obtain steady state operation, appropriate ratio of flow rate, catalyst mass and reactor geometry is required and furthermore to get more efficient production rate temperature distribution should be evenly distributed. The database obtained by the experiment will be used as a design parameter for micro reactor.

Fieldbus Communication Network Requirements for Application of Harsh Environments of Nuclear Power Plant (원전 극한 환경적용을 위한 필드버스 통신망 요건)

  • Cho, Jai-Wan;Lee, Joon-Koo;Hur, Seop;Koo, In-Soo;Hong, Seok-Boong
    • Journal of Information Technology Services
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    • v.8 no.2
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    • pp.147-156
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    • 2009
  • As the result of the rapid development of IT technology, an on-line diagnostic system using the field bus communication network coupled with a smart sensor module will be widely used at the nuclear power plant in the near future. The smart sensor system is very useful for the prompt understanding of abnormal state of the key equipments installed in the nuclear power plant. In this paper, it is assumed that a smart sensor system based on the fieldbus communication network for the surveillance and diagnostics of safety-critical equipments will be installed in the harsh-environment of the nuclear power plant. It means that the key components of fieldbus communication system including microprocessor, FPGA, and ASIC devices, are to be installed in the RPV (reactor pressure vessel) and the RCS (reactor coolant system) area, which is the area of a high dose-rate gamma irradiation fields. Gamma radiation constraints for the DBA (design basis accident) qualification of the RTD sensor installed in the harsh environment of nuclear power plant, are typically on the order of 4 kGy/h. In order to use a field bus communication network as an ad-hoc diagnostics sensor network in the vicinity of the RCS pump area of the nuclear power plant, the robust survivability of IT-based micro-electronic components in such intense gamma-radiation fields therefore should be verified. An intelligent CCD camera system, which are composed of advanced micro-electronics devices based on IT technology, have been gamma irradiated at the dose rate of about 4.2kGy/h during an hour UP to a total dose of 4kGy. The degradation performance of the gamma irradiated CCD camera system is explained.

Micro-scale Solar Energy Harvesting System with a New MPPT control (새로운 MPPT 제어기능을 갖는 마이크로 빛에너지 하베스팅 회로)

  • Yoon, Eun-Jung;Yoon, Il-Young;Choi, Sun-Myung;Park, Youn-Soo;Yu, Chong-Gun
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.17 no.11
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    • pp.2627-2635
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    • 2013
  • In this paper micro-scale solar energy harvesting system with a new MPPT control are proposed. In conventional solar energy harvesting systems, continuous perturbation techniques of the clock frequency or duty cycle of a power converter have been used to implement MPPT(Maximum Power Point Tracking) control. In this paper, we propose a new MPPT technique to control the duty cycle of a power switch powering a power converter. The proposed circuit is designed in $0.35{\mu}m$ CMOS process, and the designed chip area including pads is $770{\mu}m{\times}800{\mu}m$.

Study on Heat Transfer Characteristics of Internal Heat Exchanger for $CO_2$ Heat Pump under Heating Operating Condition (난방운전 조건하에서 $CO_2$ 열펌프용 내부 열교환기의 열전달 특성에 대한 연구)

  • Kim, Dae-Hoon;Lee, Sang-Jae;Choi, Jun-Young;Lee, Jae-Heon;Kwon, Young-Chul
    • Journal of Energy Engineering
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    • v.17 no.2
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    • pp.116-123
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    • 2008
  • In order to study the heat transfer, effectiveness and pressure drop of an internal heat exchanger (IHX) for $CO_2$, heat pump under heating condition, the experiment and numerical analysis were performed. Four kinds of IHXs were used. The section-by-section method and Hardy-Cross method were used for the numerical analysis. The effects of IHX on the flow rate of refrigerant, the IHX length, the operating condition of a gas-cooler and an evaporator and the type of IHXs were investigated. With increasing the flow rate, the heat transfer rate increased about 25%. The heat transfer of the micro-channel tube was larger about 100% than that of the coaxial tube. With increasing the IHX length, the heat transfer rate decreased. The low-side pressure drop was larger compared with that of the high-side. And the pressure drop of the microchannel tube was larger about 100% than that of the coaxial tube. With increasing the high-side temperature and decreasing the low-side temperature, the heat transfer rate increased about 3%. From this study, we can see that new correlation on $CO_2$ heat transfer characteristics and tube type is necessary.

Analysis of Volatile Fatty Acids in Air by Dynamic SPME (Dynamic SPME를 이용한 공기 중 지방산 분석)

  • Yu, Mee-Seon;Yang, Sung-Bong;Ha, Nam-Ki
    • Journal of Environmental Science International
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    • v.19 no.12
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    • pp.1447-1454
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    • 2010
  • In this study, the detection limits of lower fatty acids in air were investigated by using Dynamic SPME(Solid Phase Micro-Extraction), i.e. improved Head Space - SPME method(HS-SPME). This Dynamic SPME, called SPDE(Solid Phase Dynamic Extraction), is the analytical method for volatile compounds in air with the extraction by using a stainless steel needle of which inner surface is coated with adsorption material and following the gas chromatographic analysis by inserting the needle into a injection port of GC and subsequently, desorption of the volatile compounds into a gas-chromatographic column. Extraction was carried out by passing the sample air through the needle with a suction pump which has been used for a detection tube. The result of measurement for the 6 lower fatty acids showed that the detection limits ranged from 0.10 ppm to 0.44 ppm and the linear correlation coefficients were over 0.99. Relative standard deviations obtained from 5 analytical repetition of a ca. 1.6 ppm standard mixture were in the range of 1.87%~2.47%. This method has been shown to be a adequate for the measuring C2~C5 fatty acids in air in the concentrations of over several hundreds ppb.