• The Journal of Industrial Distribution & Business
• /
• v.10 no.1
• /
• pp.9-17
• /
• 2019

Purpose - Urban agglomeration construction is one of national strategic plans to accelerate the development of industrialization and urbanization in China, which has threatened the eco-environmental quality at the same time. This paper selected the urban agglomeration in the middle reaches of the Yangtze River as the research area. Research design, data, and methodology - The the slack-based measurement (SBM) model considering undesirable outputs is applied to measure the eco-efficiency of this urban agglomerations during 2006-2015. Results - The empirical results show that average eco-efficiency of the urban agglomeration in the middle reaches of the Yangtze River is 0.595. Regional ecological development is unbalanced. The highest eco-efficiency is recorded at Wuhan Metropolitan Area, and the lowest one is at the Changsha-Zhuzhou-Xiangtan City Group. Energy consumption and waste dust emissions are the key factors led to ecological inefficiency. Based on this, potentials for energy saving and waste dust reducing are calculated. Conclusions - Finally, this study provides policy implications targeted to promote the coordinating development of economy and eco-environment under the construction of urban agglomeration.

• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.3
• /
• pp.1269-1274
• /
• 2014

Breast tubular adenomas are rare benign breast tumors and detailed descriptions of their sonographic appearance are necessary for differential diagnosis from fibroadenomas or breast cancers. This study investigated twenty-one histology-proved tubular adenomas in 17 patients and also included 48 fibroadenomas in 35 patients as a control group. There was no significant difference between the two groups with clinical presentation, which was age, tumor location, tumor number (p>0.05). Statistic analysis showed three significant factors in the differential diagnosis of tubular adenomas and fibroadenomas, including macro-lobulation (p=0.01), "tiny branch like" patterns (p=0.001) and vascularity (p=0.02). Other ultrasonographic features such as echogenicity, border, uniformity of echotexture, posterior acoustic enhancement, lateral wall shadowing were of no clinical significance (p>0.05). Calcifications were seen in three tubular adenomas which were different from those of carcinomas. Although tubular adenomas have some typical characteristics on sonography, surgery and core needle biopsy are still needed for complex cases to exclude progress to malignancy.

• Journal of the Optical Society of Korea
• /
• v.19 no.1
• /
• pp.84-87
• /
• 2015

For large optical elements which are tested by many sub-apertures, it takes too much time for a sub-aperture stitching algorithm to get the stitching result. To solve this problem, we propose a fast sub-aperture stitching algorithm to quickly compensate for piston, tilt, and defocus errors. Moreover, the new algorithm is easy to understand and program. We use partial derivatives of measurement data to separately solve piston, tilt, and defocus errors. First, we show that the new algorithm has a lower time complexity than the currently used algorithm. Although simulation results indicate that the accuracy of the new algorithm is lower than the current algorithm in all 20 simulations, our experimental results validate the algorithm and show it is sufficiently accurate for general use.

• Carbon letters
• /
• v.28
• /
• pp.55-59
• /
• 2018

Transition-metal-embedded carbon nanotubes (CNTs) have been accepted as a novel type of sensing material due to the combined advantage of the transition metal, which possesses good catalytic behavior for gas interaction, and CNTs, with large effective surface areas that present good adsorption ability towards gas molecules. In this work, we simulate the adsorption of $O_2$ and $O_3$ onto Rh-doped CNT in an effort to understand the adsorbing behavior of such a surface. Results indicate that the proposed material presents good adsorbing ability and capacities for these two gases, especially $O_3$ molecules, as a result of the relatively large conductivity changes. The frontier molecular orbital theory reveals that the conductivity of Rh-CNT would undergo a decrease after the adsorption of two such oxidizing gases due to the lower electron activity and density of this media. Our calculations are meaningful as they can supply experimentalists with potential sensing material prospects with which to exploit chemical sensors.

• BMB Reports
• /
• v.47 no.1
• /
• pp.8-14
• /
• 2014

Telomerase plays a pivotal role in the pathology of aging and cancer by maintaining genome integrity, controlling cell proliferation, and regulating tissue homeostasis. Telomerase is essentially composed of an RNA component, Telomerase RNA or TERC, which serves as a template for telomeric DNA synthesis, and a catalytic subunit, telomerase reverse transcriptase (TERT). The canonical function of TERT is the synthesis of telomeric DNA repeats, and the maintenance of telomere length. However, accumulating evidence indicates that TERT may also have some fundamental functions that are independent of its enzymatic activity. Among these telomere-independent activities of hTERT, the role of hTERT in gene transcription has been investigated in detail. Transcriptional regulation is a fundamental process in biological systems. Several studies have shown a direct involvement of hTERT in gene transcription. This mini-review will focus on the role of hTERT in gene transcription regulation, and discuss its possible mechanisms.

• Structural Engineering and Mechanics
• /
• v.74 no.5
• /
• pp.589-600
• /
• 2020

The bonding interface of the concrete slab track and cement-asphalt mortar layer plays an important role in transferring load and restraining the track slab's deformation for slab track structures without concrete bollards in high-speed railway. However, the interfacial bond-slip behavior is seldom considered in the structural analysis; no credible constitutive model has been presented until now. Elaborating the field tests of concrete to cement-asphalt mortar interface subjected to longitudinal and transverse shear loads, this paper revealed its bond capacity and failure characteristics. Interfacial fractures all happen on the contact surface of the concrete track slab and mortar-layer in the experiments. Aiming at this failure mechanism, an interfacial mechanical model that employed the bilinear local bond-slip law was established. Then, the interfacial shear stresses of different loading stages and the load-displacement response were derived. By ensuring that the theoretical load-displacement curve is consistent with the experiment result, an interfacial bond-slip constitutive model including its the corresponding parameters was proposed in this paper. Additionally, a finite element model was used to validate this constitutive model further. The constitutive model presented in this paper can be used to describe the real interfacial bonding effect of slab track structures with similar materials under shear loads.

• Asian-Australasian Journal of Animal Sciences
• /
• v.13 no.12
• /
• pp.1779-1787
• /
• 2000

Southern and south-western Australia is a typical mediterranean environment, characterised by wet, cold winters and dry, hot summers. The evaporation rate varies significantly in summer, resulting in a high salinity of drinking water for grazing animals. In addition, a large amount of land in the cropping areas is affected by salt. Puccinellia, tall wheat grass and saltbushes have been planted to improve the soil condition and to supply feed for grazing animals. Animals grazing these areas often ingest an excessive amount of salt from soil, forage and drinking water which can reduce feed intake, increase the water requirement, depress growth and affect body composition as demonstrated in sheep. While the deer industry has been successfully developed in these regions, the potential impact of excessive salt intake on deer production is unknown. The salt tolerance has been well defined for sheep, cattle and other livestock species, but the variation between animal species, breeds within species, maturity status and grazing environments makes it impossible to apply these values directly to deer. To optimise deer production and effectively use natural resources, it is essential to understand the salt status of grazing deer and the impact of excessive salt intake on growth and reproduction of deer.

• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.18
• /
• pp.7913-7917
• /
• 2014

Apoptotic cell death plays a predominant role in histone deacetylase (HDAC) inhibitor-induced cytotoxicity. Nuclear morphological changes and activation of apoptotic executors are involved in CTS203-induced cell death. However, emerging issues of HDAC inhibitor-resistance have been observed in patients. Herein, MCF-7 cells were continuously exposed to CTS203 until the derived cells could proliferate normally in its presence. The newly obtained CTS203-resistant cells were nominated as MCF-7/203R. Compared to MCF-7 original cells, the MCF-7/203R cells were less sensitive to CTS203-induced apoptosis, with a minimal 6-fold higher $IC_{50}$ value. In contrast, the expression of Beclin-1 was dramatically up-regulated, positively correlated to the acquisition of CTS203-resistance. Our results revealed the participation of autophagy in acquired HDAC inhibitor-resistance and further identified Beclin-1 as a promising target for anti-drug resistance.

• Journal of the Optical Society of Korea
• /
• v.20 no.1
• /
• pp.101-106
• /
• 2016

A pupil filter is a useful technique for modifying the light intensity distribution near the focus of an optical system to realize depth of field (DOF) extension and superresolution. In this paper, we proposed a new design of the phase only pupil filter by using Zernike polynomials. The effect of design parameters of the new filters on DOF extension and superresolution are discussed, such as defocus Strehl ratio (S.R.), superresolution factor (G) and relative first side lobe intensity (M). In comparison with the other two types of pupil filters, the proposed filter presents its advantages on controlling both the axial and radial light intensity distribution. Finally, defocused imaging simulations are carried out to further demonstrate the effectiveness and superiority of the proposed pupil filter on DOF extension and superresolution in an optical imaging system.

• Journal of the Optical Society of Korea
• /
• v.18 no.4
• /
• pp.341-344
• /
• 2014

This study proposes a modified sub-aperture stitching algorithm, which uses an image sharpening algorithm and particle swarm optimization to improve the stitching accuracy. In sub-aperture stitching interferometers with high positional accuracy, the high-frequency components of measurements are more important than the low-frequency components when compensating for position errors using a sub-aperture stitching algorithm. Thus we use image sharpening algorithms to strengthen the high-frequency components of measurements. When using image sharpening algorithms, sub-aperture stitching algorithms based on the least-squares method easily become trapped at locally optimal solutions. However, particle swarm optimization is less likely to become trapped at a locally optimal solution, thus we utilized this method to develop a more robust algorithm. The results of simulations showed that our algorithm compensated for position errors more effectively than the existing algorithm. An experimental comparison with full aperture-testing results demonstrated the validity of the new algorithm.