• Journal of Advanced Marine Engineering and Technology
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• v.34 no.1
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• pp.147-153
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• 2010

MiTS Communication Protocol is a standard for the integrated processing and exchange of information on shipboard. It is specified in the form of state transitions as normal communication protocols. The design and implementation of such communication protocol require huge amount effort and time. To alleviate such burden, some systematic methodologies need to be devised. The design pattern may be the most adoptable one. This paper describes an object-oriented design and C++ implementation of MiTS Communication Protocol by adopting such methodology.

• Journal of Advanced Marine Engineering and Technology
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• v.34 no.1
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• pp.141-146
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• 2010

In this paper, we design and implement middleware service modules of MiTS system architecture which is proposed for integrated shipboard information management. The MiTS system is divided to three layers that are gateway, middleware server and application. The gateway collects and parses information and data, the middleware server integrates the data and stores to a database, and the application displays visual data to users. The service modules provide MiTS middleware services to gateways and applications. We implement the service modules based on international standard IEC61162-4 series and test those.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.14 no.2
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• pp.360-368
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• 2010

MiTS communication is a protocol for the exchange of various information among shipboard systems. It also specifies more than 30 specialized message formats for the information exchange. To build MiTS systems, therefore, the messages should be processed consistently. This paper proposes the design and implementation of such message processing modules. It also describes the test results of the implemented modules.

• Journal of Advanced Marine Engineering and Technology
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• v.34 no.8
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• pp.1172-1179
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• 2010

In this paper, we analyze and design requirements of Network Function block and System Function block of MiTS network protocol based on Light-Weight Ethernet, also implement and test the protocol and library files. Light-Weight Ethernet Protocol consists of Network Function block and System Function block. NF receives and sends datagram based on UDP multi-casting communication. SF processes messages after distinguished Sentence and Binary Image Data.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.6
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• pp.2943-2948
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• 2012

Arsenic exposure is a serious health hazard worldwide. We have previously established that it may result in immune suppression by upregulating Th2 cytokines while downregulating Th1 cytokines and causing lymphocytic death. Treatment modalities for arsenic poisoning have mainly been restricted to the use of chelating agents in the past. Only recently have combination therapies using a chelating agent in conjunction with other compounds such as anti-oxidants, micronutrients and various plant products, been introduced. In the present study, we used T11TS, a novel immune potentiating glycopeptide alone and in combination with the sulfhydryl-containing chelator, mono-iso-amyl-dimarcaptosuccinic acid (MiADMSA) as a therapeutic regimen to combat arsenic toxicity in a mouse model. Results indicated that Th1 cytokines such as TNF-${\alpha}$, $IFN{\gamma}$, IL12 and the Th2 cytokines such as IL4, IL6, IL10 which were respectively downregulated and upregulated following arsenic induction were more efficiently restored to their near normal levels by T11TS alone in comparison with the combined regimen. Similar results were obtained with the apoptotic proteins studied, FasL, BAX, BCL2 and the caspases 3, 8 and 9, where again T11TS proved more potent than in combination with MiADMSA in preventing lymphocyte death. The results thus indicate that T11TS alone is more efficient in immune re-establishment after arsenic exposureas compared to combination therapy with T11TS+MiADMSA.

• Journal of the Korean Chemical Society
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• v.45 no.1
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• pp.96-99
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• 2001

• Korean Journal of Remote Sensing
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• v.17 no.2
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• pp.111-119
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• 2001

This study analyzes time variability of the normalized difference vegetation index (NDVI), the leaf area index (LAI) and surface temperature (Ts) estimated from AVHRR data collected from across the Korean peninsula from 1981 to 1994. In the present study, LAI defined as vegetation density, as a function of NDVI applied for the vegetation types and Ts defined by the split-window formulation of Becker and Li (1990) with emissivity of a function of NDVI, are used. Results of the inter-annual, intra-annual and intra-seasonal variabilities in Korea show: (1) Inter-annual variability of NDVI is generally larger in the southem and eastern parts of the peninsula than in the western part. This large variability results from the significant mean variation. (2) Inter-annual variability of Ts is larger in the areas of smaller NDVI. This result shows that the NDVI play a small role in emissivity. (3) Inter-annual variability of LAI is larger in the regions of higher elevation and urban areas. Changes in LAI are unlikely to be associated with NDVI changes. (4) Changes in NDVI and Ts are likely dominant in July and are relatively small in spring and fall. (5) Urban effect would be obvious on the time-varying properties of NDVI and Ts in Seoul and the northern part of Taejon, where NDVI decreases and Ts increases with a significant magnitude.

• Journal of Advanced Marine Engineering and Technology
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• v.34 no.8
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• pp.1180-1187
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• 2010

In these days, data processing rate is increasing on shipboard. To solve the problems on the rate, Ethernet based IEC 61162-4 series standard established for integrated information management. But the standard is difficult to implement, so it is changed into Light-weight Ethernet standard. In this paper, we analyze the existing standard and compare it with Light-weight Ethernet standard. As a result, we draw its service requirements. Also we propose the services, and design and implement the service modules.

• Toxicological Research
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• v.31 no.4
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• pp.371-392
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• 2015

TS-DP2 is a recombinant human granulocyte colony stimulating factor (rhG-CSF) manufactured by TS Corporation. We conducted a four-week study of TS-DP2 (test article) in repeated intravenous doses in male and female Sprague-Dawley (SD) rats. Lenograstim was used as a reference article and was administered intravenously at a dose of $1000{\mu}g/kg/day$. Rats received TS-DP2 intravenously at doses of 250, 500, and $1000{\mu}g/kg/day$ once daily for 4 weeks, and evaluated following a 2-week recovery period. Edema in the hind limbs and loss of mean body weight and body weight gain were observed in both the highest dose group of TS-DP2 and the lenograstim group in male rats. Fibro-osseous lesions were observed in the lenograstim group in both sexes, and at all groups of TS-DP2 in males, and at doses of TS-DP2 $500{\mu}g/kg/day$ and higher in females. The lesion was considered a toxicological change. Therefore, bone is the primary toxicological target of TS-DP2. The lowest observed adverse effect level (LOAEL) in males was $250{\mu}g/kg/day$, and no observed adverse effect level (NOAEL) in females was $250{\mu}g/kg/day$ in this study. In the toxicokinetic study, the serum concentrations of G-CSF were maintained until 8 hr after administration. The systemic exposures ($AUC_{0-24h}$ and $C_0$) were not markedly different between male and female rats, between the administration periods, or between TS-DP2 and lenograstim. In conclusion, TS-DP2 shows toxicological similarity to lenograstim over 4-weeks of repeated doses in rats.

• Food Science and Biotechnology
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• v.17 no.5
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• pp.1066-1073
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• 2008

Sensitivity to 6-n-propylthiouracil (PROP) tasting predicts sensitivity to food qualities as well as rejection of some strong tasting foods. Using consumer rejection threshold (CRT) method, this study aimed to assess whether systematic changes in the taste intensities of familiar foods would lead to earlier rejection of these products by PROP tasters than by PROP non-tasters. Subjects rated the intensity of PROP solution and were divided into tasters (Ts) and non-tasters (NTs). And Ts were further divided into medium-tasters (MTs) and super-tasters (STs). Difference thresholds and CRTs were then evaluated for caffeine in coffee, citric acid in orange juice, and for NaCl in beef soup. For each food, Ts were more sensitive to variations in tastants than NTs. Ts also rejected more bitter coffee, more sour orange juice, and less salty beef soup more readily than did NTs. Comparisons among NTs, MTs, and STs gave fewer clear differences.