• Maxillofacial Plastic and Reconstructive Surgery
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• v.33 no.5
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• pp.430-434
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• 2011

Extraskeletal osteochondroma is an uncommon benign tumor that arises in soft tissues lacking continuity with an adjacent bone and joint. Due to similar histopathological findings, extraskeletal osteochondroma is often misdiagnosed for a conventional osteochondroma, the most common benign tumor that arises from the epiphyseal plates of long bones. The pathogenesis of extraskeletal osteochondroma is unclear, but metaplasia of synovial mesenchymal tissue is the best supported etiology. The most common sites of extraskeletal osteochondroma are the hands and feet, and it is rarely found in the maxillofacial area. We present a case of a two-year-old boy with a giant extraskeletal osteochondroma that developed in the masticatory space of the mandible along with a review of the relevant literature.

• 대한세포병리학회:학술대회논문집
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• 1992.06a
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• pp.23-23
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• 1992

• Imaging Science in Dentistry
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• v.32 no.1
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• pp.41-47
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• 2002

Osteochondroma is a benign lesion of osseous and cartilagenous origin. It is a relatively common benign tumor of the skeleton, occurring most often in the metaphyseal region of long bone. However, it is rare in the facial bones. Reported foci in the mandible were the condyle, coronoid process, and symphysis region. Synovial chondromatosis is an uncommon benign condition of unknown etiology which affects the articular joints. Foci of cartilage develop through metaplasia in the underlying connective tissue of the synovial membrane. These cartilagenous foci and fragments may undergo calcification and ossification. We experienced 4 patients with abnormal appearance of mandibular condyle. This report describes 3 cases of osteocondroma and 1 case of synovial chondromatosis of the mandibular condyle with review of the literature.

• Journal of Korean Neurosurgical Society
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• v.44 no.4
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• pp.256-258
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• 2008

We report a rare case of symptomatic Rathke's cleft cyst with thick calcified wall. Brain CT scans revealed a large cystic mass with round thick calcified wall. In this case, we selected the pterional approach instead of transsphenoidal approach due to the possibility of cystic craniopharyngioma. Histopathologically, it was calcified Rathke's cleft cyst with focal epithelial metaplasia. This case illustrates that calcification of the suprasellar cyst does not always suggest craniopharyngioma and the calcification pattern of Rathke's cleft cyst is different from that of the craniopharyngioma.

• Applied Microscopy
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• v.11 no.1
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• pp.21-28
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• 1981

Gastric xanthoma which is not a true neoplasm and clinically insignificant consists of the small yellowish lesion of the gastric mucosa, frequently of multiple occurrence. Histologically the lesion shows chronic superficial gastritis with intestinal metaplasia and occasional collections of foam cells within the lamina propria. Electron microscopically. the xanthoma, cells are composed of. lipid-laden histiocytes with. many autophagocytic Iysosomes surrounding the cytoplasmic lipid vacuoles. Many residual bodies are also noted. The pathogenesis of the gastric xanthoma is obscure, however it is thought that a previous focal lesion of the gastric mucosa may have been a factor. One case of gastric xanthoma is reported here and a brief review of literature is also made.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.32 no.3
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• pp.270-275
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• 2010

Although synovial chondromatosis is most frequently found in the knee, they have been reported in temporomandibular joint. Synovial chondromatosis is a cartilaginous metaplasia of the mesenchymal remnants of the synovial tissue of the joint. It is characterized by the formation of cartilaginous nodules (loose bodies) in the synovium and within the articular space. Pain and swelling are the most common symptoms of the synovial chondromatosis and somtimes deviation of the mandible toward the unafected side during motion may occur. When these lesions becom symptomatic, they should be removed surgically.

• Proceedings of the Korean Society of Applied Pharmacology
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• 2003.11a
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• pp.95-95
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• 2003

Mycoplasmas resemble H. pylori in production of ammonia and induction of inflammatory cytokines from immune and non-immne cells. In Republic of Korea infection rate of H. pylori is relatively high but only a proportion of them invite additional inflammation and progress into gastric cancers. Therefore, additional risk factors cannot be excluded. The presence and identification of mycoplasma were confirmed by semi -nested PCR and sequencing and the results were compared with pathological data. Fifty-six samples collected from Korean chronic gastritis patients were used for the study. Twenty-three (41.1%) were positive to mycoplasmas and all of them were identified as human mycoplasmas, M. faucium, M. fermentans, M. orale, M. salivarium and M. spermatophilum. Mycoplasma-infected chronic gastritis samples showed more severe, additional infiltration of neutrophils than non-infected samples and the difference was significant (P < 0.05). In conclusion human mycoplasma infection may playa role in progression of chronic gastritis to metaplasia by inducing additional inflammation.

• The Korean Journal of Cytopathology
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• v.4 no.2
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• pp.100-104
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• 1993

Sputum smears of 116 cases in 55 pulmonary tuberculosis patients with the demonstration of acid-fast bacilli in sputum were retrospectively reviewed to investigate the cytologic diagnosis of pulmonary tuberculosis in sputum. Epithelioid cells, multinucleated giant cells of Langhans or nonspecific type, or necrotic materials of caseation or nonspecific nature were found in 40% of the cases, but in 60% of the cases, only nonspecific findings including squamous metaplasia were found. Only in 6% of the cases, the cytologic diagnosis of tuberculosis was possible with the findings of epithelioid cells and muitlnucleated giant cells in a necrotic background.

• Parasites, Hosts and Diseases
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• v.41 no.1
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• pp.63-67
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• 2003

A 69-year-old Korean man was admitted to emergency room with complaints of abdominal pain, vomiting, and diarrhea, Laboratory tests revealed eosinophilia, anemia, hypoproteinemia, and hyponatremia. The gastric mucosa showed whitish mottled and slightly elevated lesions on the body angle of antrum. Microscopically, chronic gastritis with incomplete intestinal metaplasia was observed. Many adult worms, larvae, and eggs in cross sections were located in the crypts. Furthermore, the filariform larvae of Strongyloides stercoralis with a notched tail were detected through the culture.

• Korean Journal of Veterinary Research
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• v.35 no.2
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• pp.353-360
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• 1995

Gross and light microscopic findings are described for 34 canine sweat gland neoplasms including tumors derived from apocrine gland in anal sac and ceruminous gland in ear. Affected dogs are usually 5.2 years and sex predilection have not been seen. Sweat gland carcinoma(n=19) is predominant type for sweat gland neoplsm, while papillary syringadenoma(n=2) and spiradenoma(n=2) are rare type in this study. Distinct patterns identified in cutaneous sweat gland carcinoma are tubular(n=7), solid(n=5), mixed(n=4), papillary(n=2) and signet-ring(n=1). Mixed tumors which are characterized by myxomatous and chondroid metaplasia are seen in cutaneous sweat and ceruminous gland. The carcinoma derived apocrine gland of the anal sac induces humoral hypercalcemia of malignancy in two dogs in this study. Histologically, apocrine gland carcinoma of the anal sac has distinct rossette formation.