• 제목/요약/키워드: Metachronous gastric neoplasm

검색결과 4건 처리시간 0.016초

The pattern of metachronous recurrence after endoscopic submucosal dissection for gastric adenocarcinoma and dysplasias

  • Sunah Suk;Yeon Joo Seo;Dae Young Cheung;Han Hee Lee;Jin Il Kim;Soo-Heon Park
    • Clinical Endoscopy
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    • 제56권4호
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    • pp.470-478
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    • 2023
  • Background/Aims: Metachronous recurrence incidences and risk factors following endoscopic submucosal dissection (ESD) for gastric adenocarcinoma and dysplasias were investigated. Methods: Retrospective review of electronic medical records of patients who underwent gastric ESD at The Catholic University of Korea, Yeouido St. Mary's Hospital. Results: A total of 190 subjects were enrolled for analysis during the study period. The mean age was 64.4 years and the male sex occupied 73.7%. The mean observation period following ESD was 3.45 years. The annual incidence rate of metachronous gastric neoplasms (MGN) was about 3.96%. The annual incidence rate was 5.36% for the low-grade dysplasia group, 6.47% for the high-grade dysplasia group, and 2.74% for the EGC group. MGN was more frequent in the dysplasia group than in the EGC group (p<0.05). For those with MGN development, the mean time interval from ESD to MGN was 4.1 (±1.8) years. By using the Kaplan-Meier model, the estimated mean MGN free survival time was 9.97 years (95% confidence interval, 8.53-11.40) The histological types of MGN were not related to the primary histology types. Conclusions: MGN following ESD developed in 3.96% annually and MGN was more frequent in the dysplasia group. The histological types of MGN did not correlate with those of primary neoplasm.

Clinicopathologic characteristics and survival rate in patients with synchronous or metachronous double primary colorectal and gastric cancer

  • Park, Ji-Hyeon;Baek, Jeong-Heum;Yang, Jun-Young;Lee, Won-Suk;Lee, Woon-Kee
    • 대한종양외과학회지
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    • 제14권2호
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    • pp.83-88
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    • 2018
  • Purpose: Double primary colorectal cancer (CRC) and gastric cancer (GC) represent the most common multiple primary malignant tumors (MPMT) in Korea. The recognition and screening of hidden malignancies other than the primary cancer are critical. This study aimed to investigate the clinicopathologic characteristics and survival rates in patients with synchronous or metachronous double primary CRC and GC. Methods: Between January 1994 and May 2018, 11,050 patients were diagnosed with CRC (n=5,454) or GC (n=5,596) at Gil Medical Center. MPMT and metastatic malignant tumors were excluded from this study. A total of 103 patients with double primary CRC and GC were divided into two groups: the synchronous group (n=40) and the metachronous group (n=63). The incidence, clinicopathologic characteristics, and survival rate of the two groups were analyzed. Results: The incidence of synchronous and metachronous double primary CRC and GC was 0.93%. Double primary CRC and GC commonly occurred in male patients aged over 60 years with low comorbidities and minimal previous cancer history. There were significant differences between the synchronous and metachronous groups in terms of age, morbidity, and overall survival. Metachronous group patients were 6 years younger on average (P=0.009), had low comorbidities (P=0.008), and showed a higher 5-year overall survival rate (94.8% and 61.3%, P<0.001) in contrast to synchronous group. Conclusion: When primary cancer (CRC or GC) is detected, it is important to be aware of the possibility of the second primary cancer (GC or CRC) development at that time or during follow-up to achieve early detection and better prognosis.

위암 환자에 발생한 동시성과 이시성암의 임상병리학적 특성 (The Clinicopathologic Features of Synchronous and Metachronous Cancer in Patients with Gastric Cancer)

  • 유영선;최은서;김성수;민영돈
    • Journal of Gastric Cancer
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    • 제9권4호
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    • pp.256-261
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    • 2009
  • 목적: 진단 기술의 발전과 함께 위암 환자에서 동시성과 이시성암이 발견되는 빈도가 증가하고 있다. 본 연구에서는 위암에서 발견된 동시성과 이시성암의 임상병리학적 특성과 임상적 의의에 대하여 알아보고자 하였다. 대상 및 방법: 1998년 1월부터 2008년 3월까지 조선대학교병원에서 위암으로 진단된 환자들의 의무기록을 후향적으로 분석하였다. 결과: 1,048명 위암 환자 중 38명(3.6%)에서 동시성과 이시성암이 있었다. 38명 중 16명(42.1%)은 동시성암이었고 22명(57.9%)은 이시성암이었다. 위암과 이차성 원발암 간의 평균 시간간격은 $27.08{\pm}31.25$개월이었다. 가장 흔한 중복암은 폐암(8/38, 21.1%)과 대장암(8/38, 21.1%)이었다. 27명의 환자가 위암에 대하여 수술적 치료를 하였으며 이 중 5명(18.5%)은 동시성암, 22명(81.5%)은 이시성암이었다. 평균 생존 기간은 49.8개월이었으며 동시성암의 경우는 24.6개월 이시성암의 경우는 68.1개월이었고 이들의 3년 생존율은 동시성암, 이시성암 각각 33.3%, 81.1%였다. 결론: 위암에서의 이차성 원발암 진단에 대한 진단에 있어 충분한 수술 전 검사를 통한 동시성암의 발견과 지속적인 추적검사를 통한 이시성암의 발견을 위해 주의를 기울여야 한다.

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위전절제술 후 문합부에 발생된 암에 대한 수술 (Surgery for Cancer Arising at an Anastomotic Site after Radical Total Gastrctomy)

  • 윤호영;이상훈;김충배
    • Journal of Gastric Cancer
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    • 제7권3호
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    • pp.174-179
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    • 2007
  • 진단의 발달과 치료의 발전으로 위암의 치료 성적은 괄목한 성장이 이루어졌으나 근치적 위전절제술 후 암의 발생, 즉 문합부 재발암과 전이 그리고 이시성암이 발생되었을때 외과적 치료에 대한 보고와 결과는 많지 않으며, 특히 문합부에만 국소적으로 발생된 암은 흔치 않다. 근치적 위전절제술 후 문합부에만 국소적으로 발생된 암에 대하여 적극적인 수술을 함으로써 생존이 연장되었다는 보고가 있다. 연구자들은 위선암으로 근치적 위전절제술 후 발생한 문합부 국소재발 1예, 이시성 편평상피암 1예, 림프종 1예에 대하여 원격전이가 없음을 확인한 후 수술을 시행하여 모두 좋은 결과를 얻어 이에 문헌 고찰과 함께 보고하는 바이다.

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