• Title/Summary/Keyword: Metabolic quotient

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Saccharomyces cerevisiae의 물질대사에 미치는 중성자의 영향

  • 이민재
    • Journal of Plant Biology
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    • v.7 no.4
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    • pp.9-14
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    • 1964
  • According to the results measured the respiratory quotient of Saccharomyces cerevisiae with neutron radiation by manometric direct method, the respiratory quotient of them was stimulated at the dose(7$\times$106N/$\textrm{cm}^2$/sec) of neutron radiation for 60 seconds, and was inhibited in each group irradiated at the high dose (7$\times$108N/$\textrm{cm}^2$/sec) of neutron. Its physiological effects influenced on neutron had relations with respiratory quotient, reproductive rate and fermentation in the curve of normal logarithmic phase. The multiple reactions which appeared in yeast, indicated that a great deal of physiological function were closely correlated with the irradiated dosage of neutron. The kinds of free amino acid in yeast irradiated with neutron were different from those of unirradiated yeast. The activityof dehydrogenase system accelerated the metabolic function of yeast irradiated at some low dose of neutron. By this results, it may demonstrate that the fact which the phenomena obtained in the stimulation of neutron possess its character for several generation, is dependent on the theory of mutation. Subsequently, it seemed reasonable certain dominant type of microorganisms.

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A Study on Variation and Application of Metabolic Syndrome Prevalence using Geographically Weighted Regression (지리적 가중 회귀를 이용한 대사증후군 유병률의 지역별 변이에 관한 연구 및 적용 방안)

  • Suhn, Mi Ohk;Kang, Sung Hong;Chun, Jin-Ho
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.2
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    • pp.561-574
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    • 2018
  • In this study, regional variations and factors associated with prevalence of metabolic syndrome were grasped using GWR (geographically weighted regression) and methodologies for the efficient management of metabolic syndrome were then set up to resolve health inequalities. Based on the National Health Screening Statistical Yearbook published by the National Health Insurance Service (NHIS), community health survey (KCDC) and other governmental institutions, indicators of social structural and mediation factors related to the regional prevalence of metabolic syndrome were collected. First, the existence of indicators to measure variations in metabolic syndrome were confirmed with the collected data by calculating the EQ (extremal quotient) and CV (coefficient of variations). The GWR, which is able to take spatial variations into consideration, was then adopted to analyze the factors of regional variations in metabolic syndrome. The GWR analysis revealed that severity and management of the main causes need to be prioritized in accordance with the prevalence of metabolic syndrome. Consequently, the order of priority in management of regional prevalence of metabolic syndrome was established, and plans that can increase the effectiveness of management of metabolic syndrome were confirmed to be feasible.

The Development of Convenient RQ Measuring Device for Patients Real Time Monitoring (환자의 실시간 모니터링을 위한 간편한 RQ 측정기기의 개발)

  • Kim, Y.S.;Jeon, H.M.;Choi, S.W.;Shim, E.B.
    • Proceedings of the KSME Conference
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    • 2008.11a
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    • pp.1609-1612
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    • 2008
  • RQ(Respiratory Quotient) value is obtained from the ratio of the consumed oxygen and the produced carbon dioxide during the patient's respiration. To investigate the efficacy of insulin and diagnosis the metabolic disorder in short time, the RQ value can be used as important parameter. The measurement of oxygen and carbon dioxide amounts is needed large chamber and complex sensors. But If the atmospheric oxygen and carbon dioxide concentrations do not change, the expiratory oxygen and carbon dioxide can be used to obtain RQ value. A convenient RQ measuring device has been developed by using two sensors for O2 and CO2. The estimation of RQ devices confirms that the RQ device can obtain accurate data by eliminating uncertain factor such as delay time and remaining gases.

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Effects of Body Build on Metabolic and Physiological Function in Men and Athletes - 1. Especially on the Metabolic Function -

  • Lee, Ok-Hee;Lim, Soon-Gill;Lee, Jung-Hee
    • Nutritional Sciences
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    • v.2 no.2
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    • pp.93-101
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    • 1999
  • The aim of this study was to investigate influence of body build on body composition, energy metabolic state and insulin concentration of blood. 29 male athletes and 36 male non-athletic students were recruited for the study. Anthropometry including chest depth and breadth, fat mass, fat fee mass, tricep skinfold thickness were measured. fasting glucose, lactate, triglyceride, fee fatty acid, and insulin concentration in serum were measured . Body build was assessed using metric index, which calculated by regression equations of Mohr and Greil. The athletic and non-athletic students were allocated to 3 body build, that is leptomorph, mesomorph, and pyknomorph. Resting metabolic rate was calculated. Respiratory quotient was determined through ratio of measured VO$_2$, and V$CO_2$. Most non-athletes have a leptomorphic body build, in contrast to athletes mesomorphic type. The body build type influenced body composition differently between non-athletic group and athletic group. Weight, body mass index, body fat mass and fat mass proportion (%), and fat-free mass increased from leptomorph to pyknormorph in non-athletic group. Pyknormorphic athletes have a significant higher body mass index, fat mass, fat free mass than other body build type. Serum glucose, triglyceride, lactate, insulin showed significant differences only in non-athletic group between leptomorph and mesomorph. RMR increased significantly from leptomorph to mesomorph in non-athletes. There was no significant difference of RQ among 3 body build types in both athletes and non-athletes. This study gives a coherent data on body build and body composition for athletes and non-athletes students. The influence of body builds on energy metabolic status of serum was different between athletes and non-athletes.

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Chemical and Biological Indicators of Soil Quality in Conventional and Organic Farming Apple Orchards

  • Lee, Yoon-Jung;Chung, Jong-Bae
    • Journal of Applied Biological Chemistry
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    • v.50 no.2
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    • pp.88-96
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    • 2007
  • Organic farming systems based on ecological concepts have the potential to produce sustainable crop yields with no decline in soil and environmental qualities. Recent expansion of sustainable agricultural systems, including organic farming, has brought about need for development of sustainable farming systems based on value judgments for key properties of importance for farming. Chemical and microbiological properties were chosen as indicators of soil quality and measured at soil depth intervals of 5-20 and 20-35 cm in conventional and organic-based apple orchards located in Yeongchun, Gyeongbuk. The orchards were two adjacent fields to ensure the same pedological conditions except management system. Soil pH in organic farming was around 7.5, whereas below 6.0 in conventional farming. Organic farming resulted in significant increases in organic matter and Kjeldahl-N contents compared to those found with conventional management. Microbial populations, biomass C, and enzyme activities (except acid phosphatase) in apple orchard soil of organic farming were higher than those found in conventional farming. Higher microbial quotient ($C_{mic}/C_{org}$ ratio) and lower microbial metabolic quotient for $CO_2(qCO_2)$ in organic farming confirmed that organic farming better conserves soil organic carbon. Biological soil quality indicators showed significant positive correlations with soil organic matter content. These results indicate organic-based farming positively affected soil organic matter content, thus improving soil chemical and biological qualities.

Outcomes into Adulthood of Survivors Born Either Extremely Low Birthweight or Extremely Preterm

  • Doyle, Lex W
    • Neonatal Medicine
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    • v.25 no.1
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    • pp.7-15
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    • 2018
  • We need to understand the outcomes into adulthood for survivors born either extremely low birthweight (ELBW; <1,000 g) or extremely preterm (EP; <28 weeks' gestational age), particularly their blood pressure and cardiovascular metabolic status,respiratory function, growth, psychological and mental health performance, and functional outcomes. Blood pressure is higher in late adolescence and early adulthood in ELBW/EP survivors compared with controls. In some studies, expreterm survivors have higher insulin and blood lipid concentrations than controls, which may also increase their risk for later cardiovascular disease. ELBW/EP survivors have more expiratory airflow obstruction than do controls. Those who had bronchopulmonary dysplasia (BPD) in the newborn period have even worse lung function than those who did not have BPD. As a group, they are unlikely to achieve their full lung growth potential, which means that more of them are likely to develop chronic obstructive airway disease in later life. Although they are smaller than term born controls, their weight gradually rises and ultimately reaches a mean z-score close to zero in late adolescence, and they ultimately attain a height z-score close to their mid-parental height z-score. On average, ex-preterm survivors have intelligence quotient (IQ) scores and performance on tests of academic achievement approximately 2/3 SD lower than do controls, and they also perform less well on tests of attention and executive function. They have similar high rates of anxiety and depression symptoms in late adolescence as do controls. They are, however, over-represented in population registries for rarer disorders such as schizophrenia and Autism Spectrum Disorder. In cohort studies, ex-preterm survivors mostly report good quality of life and participation in daily activities, and they report good levels of self-esteem. In population studies, they require higher levels of economic assistance, such as disability pensions, they do not achieve education levels as high as controls, fewer are married, and their rates of reproduction are lower, at least in early adulthood. Survivors born ELBW/EP will present more and more to health carers in adulthood, as they survive in larger numbers.

Economic Production of $\gamma$-Interferon from Recombinant Human Cells in Serum Free Medium by a Moving Aeration Membrane Bioreactor (교반형 막 반응기를 이용한 재조합 인간 세포의 무혈청 배지에 의한 $\gamma$-Interferon의 생산)

  • Park, Young-Shik;Kim, Hyun-Kyu;Lim, Seo-Kyu;Park, Kyung-You;Lee, Hyeon-Yong
    • Microbiology and Biotechnology Letters
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    • v.22 no.4
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    • pp.389-394
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    • 1994
  • 8 X 10$^{6}$(viable cells/ml) of maximum cell density and 9000(IU/ml) of $\gamma$-IFN production were obtained at 55(ml/hr) of a perfusion rate by cultivating HSF cells using a moving membrane aeration bioreactor. This system proves to be an efficient culture process by maintaning 90% of viable cells during the whole cultivation periods. The metabolic molar quotient of glucose to lactate was 0.81 for overall ranges of glucose consumed while the evolution of ammonia was not linearly related to the consumption of glutamine. Low molar conversion ratio was observed in low consumptions of glutamine and high molar conversion ratio in high comsumptions. It also shows that the glutamolysis plays important role in the steady state conditions by evolving larger quantities of ammonia than lactate. At the above of 50 rpm, which is the optimum agitation speed for this bioreactor, the cell growth was severely affected while the IFN production was less decrea- sed, maintaing 1.5 X 10$^{-3}$(IU/cell/day) specific IFN production rate. The cumulatvie $\gamma$-IFN production was 7.2 X 10$^{8}$(IU) for 70 days of the cultivation, which yields 1 X 10$^{7}$ (IU/day) of IFN production rate. Therefore, a commercial production of $\gamma$-IFN by this culture process can be achievable by maintaining the above IFN productivity in a scaled-up culture system.

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Effects of Metal and Metalloid Contamination on Microbial Diversity and Activity in Agricultural Soils

  • Tipayno, Sherlyn C.;Chauhan, Puneet S.;Woo, Sung-Man;Hong, Bo-Hee;Park, Kee-Woong;Chung, Jong-Bae;Sa, Tong-Min
    • Korean Journal of Soil Science and Fertilizer
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    • v.44 no.1
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    • pp.146-159
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    • 2011
  • The continuous increase in the production of metals and their subsequent release into the environment has lead to increased concentration of these elements in agricultural soils. Because microbes are involved in almost every chemical transformations taking place in the soil, considerable attention has been given to assessing their responses to metal contaminants. Short-term and long-term exposures to toxic metals have been shown to reduce microbial diversity, biomass and activities in the soil. Several studies show that microbial parameters like basal respiration, metabolic quotient, and enzymatic activities, including those of oxidoreductases and those involved in the cycle of C, N, P and other elements, exhibit sensitivity to soil metal concentrations. These have been therefore, regarded as good indices for assessing the impact of metal contaminants to the soil. Metal contamination has also been extensively shown to decrease species diversity and cause shifts in microbial community structure. Biochemical and molecular techniques that are currently being employed to detect these changes are continuously challenged by several limiting factors, although showing some degree of sensitivity and efficiency. Variations and inconsistencies in the responses of bioindicators to metal stress in the soil can also be explained by differences in bioavailability of the metal to the microorganisms. This, in turn, is influenced by soil characteristics such as CEC, pH, soil particles and other factors. Therefore, aside from selecting the appropriate techniques to better understand microbial responses to metals, it is also important to understand the prevalent environmental conditions that interplay to bring about observed changes in any given soil parameter.

Food Habits and Dietary Quality by the Presence of Perceived Major Chronic Disease among Male Manufacturing Company Workers in Their 40s (40대 남자 생산직 근로자의 주요 만성질환 유병 인지 상태에 따른 식습관 및 식사의 질)

  • Eun Jeong Han;Mi-Hyun Kim
    • Journal of the Korean Dietetic Association
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    • v.29 no.4
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    • pp.230-247
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    • 2023
  • This study aimed to investigate the association between awareness of having a chronic disease with food habits and dietary quality among 320 male manufacturing workers in their 40s. Participants were categorized into groups. The first group comprised workers who were aware of having chronic diseases (ACD, n=160) and had been diagnosed with any one or more of the following major chronic diseases: Metabolic syndrome, hyperlipidemia, hypertension, obesity, and cardiovascular disease. The second group comprised those who had experienced none of the above diseases were classified as a group of people who were a ware of not having chronic diseases (ANCD, n=160). The mean age of the subjects was 44.2 years. The mean weight (P<0.001) and body mass index (BMI; P<0.01) were significantly higher in the ACD than in the ANCD group. The frequency of alcohol consumption and the number of current smokers were not significantly different between the two groups. Dietary attitudes were not significantly different between the two groups. The frequency of egg consumption was significantly higher in the ACD group (P<0.05). Picky eating, vegetable intake, checking nutrition labels, and healthy eating behavior were not significantly different between the two groups. The frequency of exercise was significantly lower in the ACD group compared to the ANCD group (P<0.05). The mean nutrition quotient (NQ) score was 51.9, with no significant difference between the two groups. Based on these results, the awareness of suffering from chronic diseases was not significantly related to dietary attitudes, food habits, and overall dietary quality among production workers. Therefore, there is a need to develop and implement nutrition education programs to inculcate an awareness of health status that can lead to dietary changes.