• Proceedings of the Korean Society of Toxicology Conference
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• 2002.11b
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• pp.190-190
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• 2002

Methamphetamine (META) is a psychostimulant and has become popular recreational drug of abuse in many countries. The neurotoxic damage caused by METH is characterized by degeneration of the dopaminergic and serotonergic systems in striatum and hippocampus.(omitted)

• Proceedings of the Korea Information Processing Society Conference
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• 2013.05a
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• pp.722-725
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• 2013

최근 시퀀싱 기술의 발전으로 생물 데이터는 폭발적으로 증가되고 있으며 이로 인하여 우리는 지놈 시대를 지나 특정 환경 내에 존재하는 생물체들의 총체적인 지놈을 다루는 메타지놈 시대에 살고 있다. 그러나 메타지노믹 데이터의 증가속도에 비해 이를 효율적으로 분석, 검토, 판별할 수 있는 파이프라인 형태의 프로그램은 전무한 실정이다. 또한, 기존 프로그램은 대부분의 관련연구자들이 다루기 힘든 리눅스 환경의 커맨드 라인 방식이며 대용량 데이터를 처리할 수 없는 제한과 처리 속도의 한계성을 가지고 있다. 이러한 문제점들을 해결하고자 윈도우 환경의 직관적인 그래픽 사용자 인터페이스로 유기적인 데이터 분석이 가능한 메타지노믹 데이터 분석 파이프라인을 설계하고 구현하였다.

• Food Science and Industry
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• v.51 no.1
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• pp.61-71
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• 2018

The evaluation of food taste is one of the important activities of human consciousness and it is practiced by sensory analysis using 5 terminal sensorial consciousness among many other functions. These consciousness activities may be conducted by 3 way branching transformation (3-WBT) logic, which choose one out of 3 options under the multi-layered consciousness decision making system. On the basis of this logic, cognitive sensory evaluation (CSE) method was developed to carry out questionnaire survey covering objective and subjective issues during consumption of food for pregnant women. The results of the CSE for several food items was presented with the Table-pattern called CSET covering consciousness factors and their effects on the food consumers.

• International Journal of Advanced Culture Technology
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• v.10 no.3
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• pp.39-46
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• 2022

This study is an attempted content analysis study to analyze recent studies on clinical practice of nursing college students to identify problems with clinical practice and provide evidence for desirable clinical practice. For data collection, a total of 14 papers published in academic journals between 2017 and 2021 were selected. The analysis method was performed according to the systematic review reporting guidelines presented by Cochrane Collaboration and the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) group. As a result of the analysis, two themes, Four sub-themes, and seventeen concepts were derived, and the clinical practice study of nursing college students showed the necessity of standardized clinical practice protocol regulations for nursing college students and respect for patient human rights. Based on the above research results, it is proposed to prepare a nursing and clinical practice protocol that can clearly present the role of nursing college students during clinical practice.

• International Journal of Computer Science & Network Security
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• v.22 no.6
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• pp.139-144
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• 2022

Technological advancements taken the health care industry by a storm by embedding sensors in human body to measure their vitals. These smart solutions provide better and flexible health care to patients, and also easy monitoring for the medical practitioners. However, these innovative solutions provide their own set of challenges. The major challenge faced by embedding sensors in body is the issue of lack of infinite energy source. This work presents a meta-heuristic based routing model using modified PSO, and adopts an energy harvesting scheme to improve the network lifetime. The routing process is governed by modifying the fitness function of PSO to include charge, temperature and other vital factors required for node selection. A reactive routing model is adopted to ensure reliable packet delivery. Experiments have been performed and comparisons indicate that the proposed Energy Harvesting and Modified PSO (EHMP) model demonstrates low overhead, higher network lifetime and better network stability.

• Journal of Microbiology and Biotechnology
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• v.33 no.12
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• pp.1552-1562
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• 2023

Soybean (Glycine max) is an important ingredient of cuisines worldwide. While there is a wealth of evidence that soybean could be a good source of macronutrients and phytochemicals with healthpromoting effects, concerns regarding adverse effects have been raised. In this work, we reviewed the current clinical evidence focusing on the benefits and risks of soybean ingredients. In breast, prostate, colorectal, ovarian, and lung cancer, epidemiological studies showed an inverse association between soybean food intake and cancer risks. Soybean intake was inversely correlated with risks of type 2 diabetes mellitus (T2DM), and soy isoflavones ameliorated osteoporosis and hot flashes. Notably, soybean was one of the dietary protein sources that may reduce the risk of breast cancer and T2DM. However, soybean had adverse effects on certain types of drug treatment and caused allergies. In sum, this work provides useful considerations for planning clinical soybean research and selecting dietary protein sources for human health.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.21
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• pp.9295-9300
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• 2014

Interleukin-17A (IL-17A) is a multifunctional cytokine which plays a crucial role in the initiation and progression of cancer. To date, several studies have investigated associations between IL-17A -197G>A (rs2275913) polymorphism and digestive cancer risk, but the results remain conflicting. We here aimed to confirm the role of this single nucleotide polymorphism (SNP) in susceptibility to digestive cancer through a systemic review and meta-analysis. Ten eligible case-control studies were identified by searching electronic databases, involving 3,087 cases and 3,815 controls. Odds ratios (ORs) and corresponding 95% confidence intervals (CIs) were used to estimate the strength of the association. The results of overall analyses indicated that the variant A allele was associated with an increased risk of digestive cancer (AA vs GG: OR=1.51, 95%CI=1.18-1.93; AA vs GG+GA: OR=1.45, 95%CI=1.12-1.87; A vs G: OR=1.21, 95%CI=1.05-1.39). In subgroup analysis stratified by specific cancer type, elevated risk among studies of gastric cancer was found (AA vs GG: OR=1.68, 95%CI=1.24-2.28; AA vs GG+GA: OR=1.62, 95%CI=1.16-2.26; A vs G: OR=1.23, 95%CI=1.04-1.46). According to ethnicity, there was evidence in the Asian populations for an association between this polymorphism and cancer risk (GA vs GG: OR=1.19, 95%CI=1.05-1.36; AA vs GG: OR=1.56, 95%CI=1.15-2.12; AA+GA vs GG: OR=1.28, 95%CI=1.13-1.44; AA vs GG+GA: OR=1.42, 95%CI=1.01-2.00; A vs G: OR=1.24, 95%CI=1.08-1.44), while in the Caucasian populations an association was found in the recessive model (AA vs GG+GA: OR=1.62, 95%CI=1.17-2.24). In conclusion, the results of this meta-analysis suggest that the IL-17A -197G>A polymorphism contributes to an increased risk of human digestive cancer, both in the Asian and Caucasian populations and especially for gastric cancer.

• Korean small business review
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• v.42 no.2
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• pp.43-67
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• 2020

Studies on technological innovation of SMEs have made remarkable growth both qualitatively and quantitatively, but each study has a limitation to generalize due to lack of data, diversity of methodologies and variables. Therefore, a systematic and comprehensive statistical approach to obtain generalized conclusions through numerous empirical studies can help both the strategic decision making of SMEs and the government's innovation policies. The purpose of this study is to comprehensively analyze the technological innovation process of SMEs through meta-analysis. For this, the antecedents of technological innovation, the relationship between technological innovation and management performance of SMEs were analyzed. The results of using 62,512 samples from 111 domestic empirical studies were as follows; First, to improve the technological innovation of SMEs, internal cooperation, innovation culture, dynamic capabilities, and absorptive capacity were important antecedents. Second, in terms of IP performance, which was introduced as a proxy for technological innovation, human resource management, technological opportunities, commercialization capabilities, financial resources, and R&D expenditure. Third, technological innovation has a medium-sized effect on financial performance, however the effect of IP performance has a small effect size. Lastly, in the relationship between technological innovation and financial performance, the method of measurement and publication type showed statistically significant moderating effects.

• Journal of Music and Human Behavior
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• v.20 no.2
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• pp.115-142
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• 2023

The purpose of this study was to analyze and evaluate music intervention research conducted with high-risk neonates in NICUs in both domestic and international settings. Seventeen music intervention studies were identified, and their characteristics, including type of music, music provider, and treatment frequency, and outcomes (i.e., neonatal vital signs) were reviewed and analyzed along with meta-analysis. For music interventions targeting high-risk neonates in NICUs, the effect sizes of the neonates' vital signs were classified as either medium or large. In addition, larger effect sizes were associated with a combination of live and recorded music, nonmusical therapists as the music providers, and treatment frequency of one to five sessions per week. These research findings verify the clinical value of music for high-risk neonates and provide insights into the selection of music elements, music delivery methods, and music providers in NICU music interventions.

• Sijohaknonchong
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• v.25
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• pp.49-73
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• 2006

The poetic theme is a unified principle of which a poet writes poems out in his work. Theme is a poet's central thought expressed in his works. And it was described on the basis of writer's view of the world and life. In this study, I divided the themes of modern Sijo into three kinds according to the materials for a poem. Especially I am interested not so much in the poems taking outer problems of human life for the subject of a poem as in poems dealing with fundamental problems of human life such as self-consciousness, death, God's presence. Firstly, in modern Sijo which deals with poet's self-reflection and self-consciousness as a poet, poets examine himself. And he intends to write poems more severely. The more poet reflects self-consciousness, the more earnestly he tries hard to write good poems. As a poet. he feels complication between real-self and ideal self, so he tries to conquer the shame made in the gab of them. And he takes writing poems into his divinely appointed work in life. A kind of meta-Sijo is written in this circumstances. Secondly, there are modern Sijo, which shows deep concerns in death problems of human life. Thanatopsis expressed in modern Sijo is connected with poet's personal experiences. In most cases, poet describes fragmentary thoughts, sorrows and agony after death of his intimate persons. In Sijo, however, poets don't dig Into the death problem deep enough because of the characteristics of genre. But it is very significant work to take various materials of death into poetic themes in Sijo in that it makes us to reflect of human attitude of life. Thirdly, the poetic themes of dealing with fundamental problems of human and God are expressed in Sijo based on Christian view of the world. In such a poems, poet complains to God who looks in illogical human situations as a spectator of vulgar realities of life. But ultimately. poet expresses deep affirmation and obedience of God in his poems. So he manifests Christianity by the poetic paradox. Such poems change over the theme of modern Sijo the superficial Problems of reality to the deep situation of life.